Search Results for compounds

Matched symptoms: … The predicted effects of acute overexposure by inhalation of Isoflurane, USP include headache, dizziness or (in extreme cases) unconsciousness. (L1471) …
Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched treatment: … Stop drug administration, establish a clear airway, and initiate assisted or controlled ventilation with pure oxygen. (L1712) …
Matched description: … subunit of ATP synthase and NADH dehydogenase. Isoflurane also binds to the GABA receptor, the large ... induces a reduction in junctional conductance by decreasing gap junction channel opening times and ... sarcoplasmic reticulum by increasing the fluidity of the lipid membrane. Also appears to bind the D …

Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched treatment: … a general rule, medical observation and supportive care are the mainstay of treatment of ... with activated charcoal is not beneficial in pure benzodiazepine overdose as the risk of adverse ... General supportive measures should be employed, along with intravenous fluids, and an adequate …
Matched description: … , thienotriazolodiazepines. This new class is easily oxidized, rapidly metabolized, and has a lower risk of ... asleep, an increase in total sleep time and a reduction in the number of awakenings. During tests ... there were not substantial changes in deep sleep. There is a reduction of REM sleep. In EEG tests of …

Matched symptoms: … Burning sensation, cough, drowsiness, headache, nausea, shortness of breath, and vomiting can ... lead to redness and pain of the contact surface. Vapors may cause irritation to skin, nose, throat ... follow inhalation or ingestion of 1,4-DCB. Moreover, its ingestion can cause diarrhoea. Eye exposure can …
Matched treatment: … for respiratory tract irritation, bronchitis, or pneumonitis. Administer oxygen and assist ventilation ... as required. Treat bronchospasm with inhaled beta2 agonist and oral or parenteral corticosteroids ... . After eye exposure, irrigate exposed eyes with copious amounts of room temperature water for at …
Matched description: … probable mechanism for the carcinogenic effects of mothballs and some types of air fresheners containing p-DCB has been identified. ... . This colorless solid has a strong odor. In terms of its structure, the molecule consists of two ... and a deodorant, most familiarly in mothballs in which it is a replacement for the more traditional …

Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched description: … risk of leaching to groundwater and is non-volatile. It is not persistent in soil or water. Whilst it ... diseases including downy mildew and blights on fruiting vegetables, tomatoes, potatoes, curcurbits ... , lettuce and grapes. It is used in combination with cymoxanil. It has a low aqueous solubility, low …

Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched treatment: … swelling and 3) not scratching the area as it can become infected. If the symptoms of a systemic ... Minor bites and stings can be treated by: 1) washing the affected area with soap and water; 2 …
Matched description: … substances which could lead to the development of insecticides and new types of muscle-relaxing ... compounds. Poneratoxin causes slow and long-lasting contractions of mammalian smooth muscles, blocks ... synaptic transmission by changing the kinetics of the voltage-dependent sodium channels and affects the …

Matched symptoms: … Adverse effects from the cosmetic use of botulinum toxin include headaches, focal facial paralysis ... , muscle weakness, dysphagia, flu-like syndromes, and allergic reactions. (L1776) …
Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched treatment: … Treatment consists of antitoxin administration and artificial ventilation until the neurotoxins are ... Antitoxin and Heptavalent (A,B,C,D,E,F,G) Botulinum Antitoxin. (L1776) …
Matched description: … is the most toxic protein known, it may be used in minute doses to treat muscle spasms and in cosmetic treatment, under the brand name Botox. (L1776) …

Matched symptoms: … Adverse effects from the cosmetic use of botulinum toxin include headaches, focal facial paralysis ... , muscle weakness, dysphagia, flu-like syndromes, and allergic reactions. (L1776) …
Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched treatment: … Treatment consists of antitoxin administration and artificial ventilation until the neurotoxins are ... Antitoxin and Heptavalent (A,B,C,D,E,F,G) Botulinum Antitoxin. (L1776) …
Matched description: … is the most toxic protein known, it may be used in minute doses to treat muscle spasms and in cosmetic treatment, under the brand name Botox. (L1776) …

Matched symptoms: … , headache, fatigue, exercise intolerance, dizziness and loss of consciousness. Severe methemoglobinemia may cause dysrhythmias, seizures, coma and death. (L1613) ... Symptoms of methemoglobinemia include shortness of breath, cyanosis, mental status changes …
Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched treatment: … Methemoglobinemia can be treated with supplemental oxygen and methylene blue 1% solution at 1-2mg …
Matched description: … leather. It is also used in the synthesis of drugs such as paracetamol, phenetidine, and ... presence and magnitude of exposures to pesticides. (A7736) (Methods in Biotechnology, 2006,61-78) (L1661, L1662) ... 4-Nitrophenol is a phenolic compound that is used mainly to make fungicides and dyes, and to darken …

Matched symptoms: … Contact with Lonomia venom can cause massive internal haemorrhaging, kidney failure, and ... destruction of blood cells (haemolysis). This resulting medical syndrome is sometimes called Lonomiasis. (L1020) …
Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched description: … Lopap is a toxin produced by the caterpillars of the Lonomia moths (especially the species Lonomia ... obliqua). It is an anticoagulant and is being researched for pharmaceutical purposes. (L1020) …

Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched description: … used in the treatment of psychoses. Its properties and uses are generally similar to those of ... the brain; depresses the release of hypothalamic and hypophyseal hormones and is believed to depress ... chlorpromazine. [PubChem]Fluphenazine blocks postsynaptic mesolimbic dopaminergic D1 and D2 receptors in …

Matched symptoms: … Cyanide poisoning is identified by rapid, deep breathing and shortness of breath, general weakness ... , giddiness, headaches, vertigo, confusion, convulsions/seizures and eventually loss of consciousness. (L96, L97) …
Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched description: … Linamarin is found in coffee and coffee products. Linamarin occurs in manioc (Manihot utilissimus ... ), flax (Linum usitatissimum), Phaseolus lunatus (butter bean), Trifolium repens (white clover) and other plants. First isloated in 1830. …

Matched symptoms: … Cyanide poisoning is identified by rapid, deep breathing and shortness of breath, general weakness ... , giddiness, headaches, vertigo, confusion, convulsions/seizures and eventually loss of consciousness. (L96, L97) …
Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched treatment: … Antidotes to cyanide poisoning include hydroxocobalamin and sodium nitrite, which release the ... cyanide from the cytochrome system, and rhodanase, which is an enzyme occurring naturally in mammals that …
Matched description: … Acetone cyanohydrin is a chemical compound of cyanide. It is used in the production of methyl ... methacrylate, the monomer of the transparent plastic polymethyl methacrylate (PMMA), also known as acrylic. …

Matched symptoms: … Exposure of 0.1 to 1 μmol/mol produces headaches, burning eyes and irritation to the respiratory ... passages. Exposure to 10 ppm ozone will cause pulmonary edema. Low doses act as a depressant and will induce sleep in certain individuals. …
Matched carcinogenicity: … No indication of carcinogenicity (not listed by IARC) (L135). Tests in mice found no carcinogenic effect (A15094). …
Matched treatment: … EYES: Hold eye open and rinse slowly and gently with water for 15-20 minutes. Remove contact lenses ... doctor for treatment advice. INHALATION: Move person to fresh air. If person is not breathing, call …
Matched description: … action of ultraviolet light and also atmospheric electrical discharges. It is present in low ... , and also tissues in plants, above concentrations of about 100 ppb. Ozone's odor is sharp ... , reminiscent of chlorine, and detectable by many people at concentrations of as little as 10 ppb in air. Ozone …

Matched symptoms: … Ingestion of Clostridium perfringens causes food poisoning characterized by colic, diarrhoea and ... sometimes nausea. Infections show evidence of tissue necrosis, bacteremia, emphysematous ... cholecystitis, and gas gangrene, which is also known as clostridial myonecrosis. (L1804) …
Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched description: … phospholipase C (PLC) and sphingomyelinase activity. Clostridium perfringens alpha toxin is ... responsible for gas gangrene and myonecrosis in infected tissues. It also possesses hemolytic activity. (L1805) …

Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched treatment: … intravenously) and supportive measures to maintain respiration and circulation. Epinephrine (0. 3 mg ... to 1. 0 mg, subcutaneously or intramuscularly) may also be of value in the presence of severe cardiovascular depression or bronchoconstriction. (L1712) …
Matched description: … secretion by the exocrine glands, and produces contraction of the iris sphincter muscle and ciliary muscle ... hydrolyzed muscarinic agonist with no nicotinic effects. Pilocarpine is used as a miotic and in the ... treatment of glaucoma. [PubChem]Pilocarpine is a cholinergic parasympathomimetic agent. It increase …

Matched carcinogenicity: … Not listed by IARC. …
Matched description: … . Beauvericin is active against Gram-positive bacteria and mycobacteria, and is also capable of inducing programmed cell death in mammals. (L1962) ... Beauvericin is a mycotoxin with antibiotic and insecticidal effects. It was isolated from the ... species. It may therefore occur in grain (such as corn, wheat and barley) contaminated with these fungi …

Matched symptoms: … , vasomotor collapse frequently accompanied by irregular respiration, and death within a few hours of onset of these symptoms. ... Toxic reactions including fatalities have occurred in the premature and newborn; the signs and ... (in order of appearance) abdominal distension with or without emesis, progressive pallid cyanosis …
Matched description: … An antibiotic first isolated from cultures of Streptomyces venequelae in 1947 but now ... produced synthetically. It has a relatively simple structure and was the first broad-spectrum antibiotic ... to be discovered. It acts by interfering with bacterial protein synthesis and is mainly …

Matched symptoms: … Nearly all of the women who receive mifepristone will report adverse reactions, and many can be ... expected to report more than one such reaction. About 90% of patients report adverse reactions ... following administration of misoprostol on day three of the treatment procedure. Side effects include more …
Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched treatment: … effects of excess acetylcholine and reactivate AChE. Atropine can be used as an antidote in ... . Atropine is a muscarinic antagonist, and thus blocks the action of acetylcholine peripherally. ... bicarbonate. For skin contact, the skin should be washed with soap and water. If the compound has entered …
Matched description: … A progestational and glucocorticoid hormone antagonist. Its inhibition of progesterone induces ... bleeding during the luteal phase and in early pregnancy by releasing endogenous prostaglandins from the ... hypercortisolism in patients with nonpituitary cushing syndrome [PubChem]. The two marketed forms of …

Matched symptoms: … irritation to the skin or intestinal mucosa, including skin irritation, burning and itching, rash or ... blisters, and bleeding. Eye contact can cause tearing, eye pain, conjunctivitis, burning sensations ... about the eyes, and blurred vision for up to 1 week. Symptoms also include nausea, vomiting, fatigue …
Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched treatment: … with inhaled beta2 agonist and oral or parenteral corticosteroids. In case of eye exposure ... hemopoietic abnormalities, gastrointestinal damage, and skin damage. Administer charcoal as a slurry in ... case of acute oral exposure. In case of inhalation: Move patient to fresh air. Monitor for …
Matched description: … characterized by the presence of an epoxide ring and a benzoyran derivative with a variant number of ... Monoacetoxyscirpenol is a mycotoxin from Fusarium roseum and Fusarium sulphureum ... Monoacetoxyscirpenol belongs to the family of Trichothecenes. These are sesquiterpene mycotoxins structurally …

Matched symptoms: … Acetochlor is mildly irritating to the skin and eyes. Exposure to metalaxyl often results in such ... nonspecific symptoms as headache, dizziness, weakness, and nausea. Acetochlor poisoning can produce ... an allergic hypersensitivity dermatitis or asthma with bronchospasm and wheezing with chronic exposure (T36). …
Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched description: … Acetochlor is an herbicide developed by Monsanto and Zeneca. It is a member of the class of herbicides known as chloroacetanilides (L920). …

Matched symptoms: … drowsiness, weakness, excessive salivation, decreased blood pressure, difficulty breathing, and paralysis of ... the facial muscles, lips, tongue, and larynx. In addition, ptosis, blurring of vision, convulsions, and headache may occur. (T156) ... Bites from snakes in the Elapidae family produce pain at the site of the bite, followed by …
Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched description: … myotoxic and inhibits neuromuscular transmission by blocking acetylcholine release from the nerve termini. (T170) …

Matched symptoms: … , likely due to the sulfoxide metabolites of DMSO. [Wikipedia] …
Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched treatment: … In case of accidental oral ingestion, specifc measures should be taken to induce emesis. Additional ... measures which may be considered are gastric lavage, activated charcoal and force diuresis. (L1712) …
Matched description: … ability to dissolve a wide range of chemical compounds and its minimal interference with the sample ... of cryoprotectant vitrification mixtures used to preserve organs, tissues, and cell suspensions. It ... is particularly important in the freezing and long-term storage of embryonic stem cells and …

Matched symptoms: … Many-banded krait bites can cause paralysis, respiratory failure and death. (L1089) …
Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched description: … is a neurotoxin and acts at the presynaptic terminal, where it causes release of acetylcholine and ... subsequent exhaustion of acetylcholine stores in the nerve terminal. (L1091) …

Matched symptoms: … Stings from the Yellow scorpion are painful but not usually fatal. (L1042) …
Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched description: … hyperexcitability of the nervous system. It is a close homologue of agitoxin and both toxins come from Leiurus quinquestriatus hebraeus. (L1041) …

Matched symptoms: … the body and can cause nausea, vomiting, loss of appetite, and weight loss. It can also cause ... . Shortness of breath from fluid buildup in the space between the lungs and the chest wall (pleural effusion) can also be present. ... As a uremic toxin, this compound can cause uremic syndrome. Uremic syndrome may affect any part of …
Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched treatment: … Kidney dialysis is usually needed to relieve the symptoms of uremic syndrome until normal kidney function can be restored. …
Matched description: … lead to a number of conditions including renal damage, chronic kidney disease and cardiovascular ... disease. Precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central ... and autonomic neurotransmitter. Norepinephrine is the principal transmitter of most postganglionic …