Search Results for compounds

Matched symptoms: … Symptoms of central nervous system depression to the point of somnolence or coma. Agitation and ... restlessness may also occur. Other possible manifestations include convulsions, EKG changes and cardiac ... arrhythmias, fever and autonomic reactions such as hypotension, dry mouth and ileus; LD₅₀=400mg/kg (orally in mice) …
Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched description: … phenothiazine antipsychotic used principally in the treatment of nausea; vomiting; and vertigo. It is more ... , 30th ed, p612) The mechanism of action of prochlorperazine has not been fully determined, but may ... anticholinergic and alpha-adrenergic receptors, the blockade of alpha(1)-adrenergic receptors resulting in sedation, muscle relaxation, and hypotension. …

Matched symptoms: … Symptoms of overdose include cold, clammy skin, flaccid muscles, fluid in the lungs, lowered blood ... pressure, "pinpoint" or dilated pupils, sleepiness leading to stupor and coma, slowed breathing, and slow pulse rate. …
Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched treatment: … of a patent airway and institution of assisted or controlled ventilation. Supportive measures ... (including oxygen, vasopressors) should be employed in the management of circulatory shock and pulmonary ... In the treatment of morphine overdosage, primary attention should be given to the re- establishment …
Matched description: … central nervous system and on smooth muscle. The precise mechanism of the analgesic action of ... alkaloid in opium and the prototype opiate analgesic and narcotic. Morphine has widespread effects in the ... morphine is unknown. However, specific CNS opiate receptors have been identified and likely play a role in …

Matched symptoms: … , fever, headache, weakness, dryness of the nose and throat, chest pain, and coughing. Ingestion of ... shortness of breath, general weakness, giddiness, headaches, vertigo, confusion, convulsions/seizures and eventually loss of consciousness. (L6, L96, L97) ... Acute inhalation of cadmium fumes results in metal fume fever, which is characterized by chills …
Matched treatment: … Cadmium poisoning is treated by removal from exposure and supportive care. If ingested, induced ... and sodium nitrite, which release the cyanide from the cytochrome system, and rhodanase, which is an …
Matched description: … Cadmium cyanide is a chemical compound of cadmium and cyanide prepared by treating a concentrated ... aqueous solution of cadmium chloride or cadmium nitrate with potassium cyanide or sodium cyanide. It ... is used as an electrolyte for electrodeposition of thin metallic cadmium coatings on metal to …

Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched description: … restrictus. It is a highly specific ribotoxin and inhibits protein synthesis by cleaving the 28S RNA and of eukaryotic ribosomes. (A3084, A3086) ... alpha-Sarcin is a protein mycotoxin produced by the fungi Aspergillus giganteus and Aspergillus …

Matched symptoms: … exposure. Skin or eye contact can cause pain and redness of the exposed surface. (T64, L741) ... Abdominal pain, vomiting, diarrhea can result from inhalation of antimony. Dyspnea, headache ... , vomiting,cough, conjunctivitis, and bloody purulent discharge from nose can result from inhalation …
Matched treatment: … agonist and oral or parenteral corticosteroids. In case of eye exposure, irrigate exposed eyes with ... pneumonitis. Administer oxygen and assist ventilation as required. Treat bronchospasm with inhaled beta2 ... copious amounts of room temperature water for at least 15 minutes. Following dermal exposure, remove …
Matched description: … commercial compound of antimony. It is found in nature as the minerals valentinite and senarmontite ... . Antimony is a metallic element with the chemical symbol Sb and atomic number 51. Small amounts of antimony are found in the earth's crust. (L741, L760) …
Matched synonyms: … Flowers of Antimony …

Matched symptoms: … Symptoms of overdose include agitation, coma, convulsions, difficulty breathing, difficulty ... swallowing, dry mouth, extreme sleepiness, fever, intestinal blockage, irregular heart rate, low blood pressure, and restlessness. …
Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched description: … dopamine D2 receptors and inhibits their activity. The mechanism of the anti-emetic effect is due ... phenothiazine used as an antipsychotic agent and as an antiemetic. Triflupromazine binds to the dopamine D1 and ... predominantly to blockage of the dopamine D2 neurotransmitter receptors in the chemoreceptor trigger …

Matched symptoms: … Coma, respiratory depression, circulatory collapse, and pulmonary edema. Seizures occur more …
Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched treatment: … markedly reduce the degree of respiratory depression, and 0.4 to 2 mg should be administered promptly ... functions is not obtained, naloxone should be repeated at 2- to 3-minute intervals. The duration of action ... Attention should be directed first to establishing a patent airway and to restoring ventilation …
Matched description: … and negative, of synaptic transmission via G-proteins that activate effector proteins. Binding of the ... adenylate cyclase and cAMP located at the inner surface of the plasma membrane, opioids decrease ... such as propoxyphene also inhibit the release of vasopressin, somatostatin, insulin, and glucagon …

Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched description: … 3,4-Dimethylphenol is found in coffee and coffee products. 3,4-Dimethylphenol is present in coffee ... . 3,4-Dimethylphenol is a flavouring ingredient. 3,4-Dimethylphenol belongs to the family of Meta ... Cresols. These are aromatic compounds containing a meta-cresol moiety, which consists of a benzene ring …

Matched symptoms: … Bromine vapour causes irritation and direct damage to the mucous membranes. Symptoms include ... lacrimation, rhinorrhoea, eye irritation with mucous secretions from the oropharyngeal and upper airways ... , coughing, dyspnoea, choking, wheezing, epistaxis, and headache. The bromide ion is a central nervous …
Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched treatment: … EYES: irrigate opened eyes for several minutes under running water. INGESTION: do not induce ... cold running water for at least 15 minutes, followed by thorough washing with soap and water. If ... necessary, the person should shower and change contaminated clothing and shoes, and then must seek …
Matched description: … 1-Bromohexane is an organobromide compound. It is used to manufacture pharmaceuticals and organic ... chemicals. Bromine is a halogen element with the symbol Br and atomic number 35. Diatomic bromine ... does not occur naturally, but bromine salts can be found in crustal rock. (L625, L684) …

Matched symptoms: … Exposure to high levels of DNOC for short periods may cause convulsions, unconsciousness, and death ... DNOC exposure may include difficulty in breathing, headache, drowsiness, dizziness, and a yellowing of skin and the whites of the eyes. (L198) ... . Exposure to low levels of DNOC may result in an increased basal metabolic rate, increased sweating …
Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched description: … of manufactured chemicals. 4,6-Dinitro-o-cresol (DNOC) is used primarily for insect control and ... 4,6-Dinitro-o-cresol is the most commercially important of the 18 different dinitrocresols, a class ... crop protection. It may be sold under different trade names, including Antinonnin, Detal, and Dinitrol …

Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched treatment: … Administration of Vitamin K is the antidote for dicoumarol toxicity. (L1960) …
Matched description: … -carboxylation and subsequent activation of the vitamin K-dependent coagulant proteins. The synthesis ... of vitamin K-dependent coagulation factors II, VII, IX, and X and anticoagulant proteins C and S is ... , and X) results in decresed prothrombin levels and a decrease in the amount of thrombin generated …

Matched symptoms: … Short-term oral exposure to high concentrations of selenium may cause nausea, vomiting, and ... to either of these air-borne forms can cause respiratory irritation, bronchial spasms, and coughing. (L619) ... diarrhea. Brief exposures to high levels of elemental selenium or selenium dioxide in air can result in …
Matched carcinogenicity: … 3, not classifiable as to its carcinogenicity to humans. (L135) …
Matched treatment: … EYES: irrigate opened eyes for several minutes under running water. INGESTION: do not induce ... water for at least 15 minutes, followed by thorough washing with soap and water. If necessary, the ... person should shower and change contaminated clothing and shoes, and then must seek medical attention …
Matched description: … Gallium(III) selenide is a chemical compound of gallium and selenium. Selenium is a nonmetal ... most animals, forming the active center of the enzymes glutathione peroxidase, thioredoxin reductase, and three known deiodinase enzymes. (L620) ... element with the atomic number 34 and the chemical symbol Se. Selenium rarely occurs in its elemental …

Matched symptoms: … Bromine vapour causes irritation and direct damage to the mucous membranes. Symptoms include ... lacrimation, rhinorrhoea, eye irritation with mucous secretions from the oropharyngeal and upper airways ... , coughing, dyspnoea, choking, wheezing, epistaxis, and headache. The bromide ion is a central nervous …
Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched treatment: … EYES: irrigate opened eyes for several minutes under running water. INGESTION: do not induce ... cold running water for at least 15 minutes, followed by thorough washing with soap and water. If ... necessary, the person should shower and change contaminated clothing and shoes, and then must seek …
Matched description: … of the benzyl protecting group for alcohols and carboxylic acids. Benzyl bromide is a also strong ... lachrymator, as well as being intensely irritating to skin and mucous membranes. Because of these ... properties, it has been used as a war gas. Bromine is a halogen element with the symbol Br and atomic …

Matched symptoms: … , and breathing problems, such as asthma, cough, shortness of breath, or wheezing. Ingestion of ... Chromium in its trivalent state is not very toxic, but it may be oxidized to hexavalent chromium ... . Breathing hexavalent chromium can cause irritation to the lining of the nose, nose ulcers, runny nose …
Matched carcinogenicity: … No indication of carcinogenicity (not listed by IARC). (L135) …
Matched description: … Chromium(II) acetate is a coordination compound of chromium. It is used the polymer industry, to ... dehalogenate organic compounds such as α-bromoketones and chlorohydrins, and as an oxygen scrubber ... . Chromium is a chemical element which has the symbol Cr and atomic number 24. It is found naturally …

Matched symptoms: … Bromine vapour causes irritation and direct damage to the mucous membranes. Symptoms include ... lacrimation, rhinorrhoea, eye irritation with mucous secretions from the oropharyngeal and upper airways ... , coughing, dyspnoea, choking, wheezing, epistaxis, and headache. The bromide ion is a central nervous …
Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched treatment: … EYES: irrigate opened eyes for several minutes under running water. INGESTION: do not ... in cold running water for at least 15 minutes, followed by thorough washing with soap and water. If ... necessary, the person should shower and change contaminated clothing and shoes, and then must seek …
Matched description: … Indium(I) bromide is a chemical compound of indium and bromine. It has been used in the sulfur lamp ... and in organic chemistry. Bromine is a halogen element with the symbol Br and atomic number 35 ... . Diatomic bromine does not occur naturally, but bromine salts can be found in crustal rock. (L625, L652) …

Matched symptoms: … Breathing 1,3-butadiene may cause irritation of the eyes, nose, and throat. High levels of 1,3 ... -butadiene can also cause, blurred vision, nausea, fatigue, headache, decreased blood pressure and pulse ... rate, and unconsciousness. Skin contact with liquid 1,3-butadiene can cause irritation and frostbite. (L990) …
Matched description: … generation of sulfur dioxide byproduct in the reaction mixture is not objectionable. Long-term exposure has ... used in the industrial production of 4-vinylcyclohexene via a Diels Alder dimerization reaction and ... , respectively. Butadiene is also useful in the synthesis of cycloalkanes and cycloalkenes, as it …

Matched symptoms: … , increased or decreased blood pressure, numbness around the face, and muscle weakness. High levels ... may result in changes in heart rhythm or paralysis and possibly death. (L214) …
Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched treatment: … Intravenous infusion of potassium often relieves many of the symptoms of barium toxicity. (L214) …
Matched description: … Barium azide is a chemical compound of barium. Barium is a metallic alkaline earth metal with the ... symbol Ba, and atomic number 56. It never occurs in nature in its pure form due to its reactivity ... with air, but combines with other chemicals such as sulfur or carbon and oxygen to form barium compounds that may be found as minerals. (L214, 408) …

Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched treatment: … reverse peripheral ischemia secondary to vasoconstriction and for the treatment of hypertension …
Matched description: … polymerization and the elongation of actin. As a result, they can change cellular morphology, inhibit cellular ... Cytochalasins are mycotoxins that have the ability to bind to actin filaments and block ... processes such as cell division, and cause cells to undergo apoptosis. Cytochalasins also have the …

Matched symptoms: … Sphingomyelinase D is highly necrotic and causes significant tissue damage. Symptoms include nausea ... , vomiting, fever, rashes, and muscle and joint pain. Rarely more severe symptoms occur including ... haemolysis, thrombocytopenia, and disseminated intravascular coagulation. This condition is termed loxoscelism. (L1030) …
Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched description: … is highly necrotic and causes significant tissue damage. (L1030) …

Matched symptoms: … Symptoms of overdose include primarily sleepiness and mild dysphoria. …
Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched treatment: … specific antidote. Oxygen, intravenous fluids, vasopressors and other supportive measures should be used as indicated. (L1712) …
Matched description: … a pain medication. It appears to be an agonist at kappa opioid receptors and an antagonist or ... partial agonist at mu opioid receptors. [PubChem]The exact mechanism of action is unknown, but is ... , but may also be a result of other mechanisms. Nalbuphine is thought primarily to be a kappa agonist …

Matched symptoms: … to pulmonary edema, bloody sputum, and bronchial pneumonia. At high amounts, central nervous system ... depression may also occur, with symptoms such as weakness, dizziness, slow and shallow respiration ... , unconsciousness, and convulsions. Petroleum distillates are also irritating to the skin. (A594) …
Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched treatment: … Treatment is mainly symptomatic and supportive. Gastric lavage, emesis, and the administration of ... activated charcoal should be avoided, as vomiting increases the risk of aspiration. (A600) …
Matched description: … Octane is an alkane with the chemical formula C8H18. It has 18 isomers. One of the isomers, 2,2,4 ... -trimethylpentane or isooctane, is of major importance, as it has been selected as the 100 point on ... represent the anti-knock performance of petroleum-based fuels (octane is less likely to prematurely combust …

Matched symptoms: … High doses of naltrexone (generally ≥1,000 mg/kg) produce salivation, depression/reduced activity, tremors, and convulsions. …
Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched description: … Derivative of noroxymorphone that is the N-cyclopropylmethyl congener of naloxone. It is a narcotic ... antagonist that is effective orally, longer lasting and more potent than naloxone, and has been ... proposed for the treatment of heroin addiction. The FDA has approved naltrexone for the treatment of alcohol dependence. [PubChem] …

Matched symptoms: … Symptoms of low dose exposure include excessive salivation and eye-watering. Acute dose symptoms ... include severe nausea/vomiting, salivation, sweating, bradycardia, hypotension, collapse, and ... convulsions. Increasing muscle weakness is a possibility and may result in death if respiratory muscles are …
Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched treatment: … effects of excess acetylcholine and reactivate AChE. Atropine can be used as an antidote in ... . Atropine is a muscarinic antagonist, and thus blocks the action of acetylcholine peripherally. ... bicarbonate. For skin contact, the skin should be washed with soap and water. If the compound has entered …
Matched description: … Azamethiphos is an organophosphorus insecticide that acts by inhibition of cholinesterase activity …

Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched treatment: … reverse peripheral ischemia secondary to vasoconstriction and for the treatment of hypertension …
Matched description: … polymerization and the elongation of actin. As a result, they can change cellular morphology, inhibit cellular ... Cytochalasins are mycotoxins that have the ability to bind to actin filaments and block ... processes such as cell division, and cause cells to undergo apoptosis. Cytochalasins also have the …

Matched symptoms: … system effects, which include movements that may become slow and clumsy. This combination of symptoms ... Manganese mainly affects the nervous system and may cause behavioral changes and other nervous …
Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched treatment: … EYES: irrigate opened eyes for several minutes under running water. INGESTION: do not induce ... water for at least 15 minutes, followed by thorough washing with soap and water. If necessary, the ... person should shower and change contaminated clothing and shoes, and then must seek medical attention …
Matched description: … Manganese oxide is an oxide of manganese where the manganese is present in both the 2+ and 3 ... the production of soft ferrites and lithium manganese oxide, as well as in lithium batteries ... . Manganese is a naturally occurring metal with the symbol Mn and the atomic number 25. It does not occur …