Browsing Toxins
Displaying toxin 2751 - 2775 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D3716 | Trichodermin 4682-50-2 | C17H24O4 292.370 g/mol |  |
| Unlike many other mycotoxins, trichothecenes do not require metabolic activation to exert their biological activity, instead directly reacting with cellular components...more Number of Targets: 2 |
| T3D3717 | Trichodermol 2198-93-8 | C15H22O3 250.333 g/mol |  |
| Unlike many other mycotoxins, trichothecenes do not require metabolic activation to exert their biological activity, instead directly reacting with cellular components...more Number of Targets: 2 |
| T3D3718 | Trichothecin 6379-69-7 | C19H24O5 332.391 g/mol |  |
| Unlike many other mycotoxins, trichothecenes do not require metabolic activation to exert their biological activity, instead directly reacting with cellular components...more Number of Targets: 2 |
| T3D3719 | Trichothecolone 2199-06-6 | C15H20O4 264.317 g/mol |  |
| Unlike many other mycotoxins, trichothecenes do not require metabolic activation to exert their biological activity, instead directly reacting with cellular components...more Number of Targets: 2 |
| T3D3720 | Verrucarin A 3148-09-2 | C27H34O9 502.554 g/mol |  |
| Unlike many other mycotoxins, trichothecenes do not require metabolic activation to exert their biological activity, instead directly reacting with cellular components...more Number of Targets: 2 |
| T3D3721 | Verrucarin B 2290-11-1 | C27H32O9 500.538 g/mol |  |
| Unlike many other mycotoxins, trichothecenes do not require metabolic activation to exert their biological activity, instead directly reacting with cellular components...more Number of Targets: 2 |
| T3D3722 | Verrucarin J 4643-58-7 | C27H32O8 484.538 g/mol |  |
| Unlike many other mycotoxins, trichothecenes do not require metabolic activation to exert their biological activity, instead directly reacting with cellular components...more Number of Targets: 2 |
| T3D3723 | Verrucarol 2198-92-7 | C15H22O4 266.333 g/mol |  |
| Unlike many other mycotoxins, trichothecenes do not require metabolic activation to exert their biological activity, instead directly reacting with cellular components...more Number of Targets: 2 |
| T3D3724 | Bovinocidin 504-88-1 | C3H5NO4 119.076 g/mol |  |
| 3-Nitropropionic acid is a suicide inhibitor of succinate dehydrogenase, an enzyme required for the activity of the tricarboxylic acid (TCA) cycle as well as mitochond...more Number of Targets: 4 |
| T3D3725 | Aflatoxicol 29611-03-8 | C17H14O6 314.290 g/mol |  |
| Aflatoxins produce singlet oxygen upon their exposure to UV (365-nm) light. Singlet oxygen in turn activates them to mutagens and DNA binding species. Aflatoxin metabo...more Number of Targets: 1 |
| T3D3726 | Aflatrem 70553-75-2 | C32H39NO4 501.656 g/mol |  |
| Tremorgenic mycotoxins exert their toxic effects by interfering with neurotransmitter release, possibly by causing degeneration of nerve terminals. They are thought to...more Number of Targets: 26 |
| T3D3727 | Alternariol 641-38-3 | C14H10O5 258.226 g/mol |  |
| Alternariol is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholinest...more Number of Targets: 7 |
| T3D3728 | Alternariol methyl ether 23452-05-3 | C15H12O5 272.253 g/mol |  |
| Alternariol methyl ether has been shown to have genotoxic and mutagenic properties. It has demonstrated DNA-damaging activities such as single-strand and double-strand...more Number of Targets: 4 |
| T3D3729 | Altertoxin-1 56258-32-3 | C20H16O6 352.337 g/mol |  |
| Altertoxin-1 has been shown to have genotoxic and mutagenic properties. It has demonstrated DNA-damaging activities such as single-strand and double-strand DNA breaks,...more Number of Targets: 4 |
| T3D3730 | Rubratoxin B 21794-01-4 | C26H30O11 518.510 g/mol |  |
| Rubratoxin B is cytotoxic, hinders cell proliferation, and induces apoptosis. It also inhibits the activity of matrix metalloproteinase-2 and -9. Rubratoxin B causes d...more Number of Targets: 20 |
| T3D3731 | Rubratoxin A 22467-31-8 | C26H32O11 520.526 g/mol |  |
| Rubratoxin A is a potent inhibitor of protein phosphatase 2A, exerting antitumor and antimetastatic effects. Inhibition may cause the phosphorylation of CREB and subse...more Number of Targets: 12 |
| T3D3732 | Penitrem A 12627-35-9 | C37H44ClNO6 634.201 g/mol |  |
| Tremorgenic mycotoxins exert their toxic effects by interfering with neurotransmitter release, possibly by causing degeneration of nerve terminals. They are thought to...more Number of Targets: 27 |
| T3D3733 | Penitrem B 11076-67-8 | C37H45NO5 583.757 g/mol |  |
| Tremorgenic mycotoxins exert their toxic effects by interfering with neurotransmitter release, possibly by causing degeneration of nerve terminals. They are thought to...more Number of Targets: 27 |
| T3D3734 | Penitrem C 37318-84-6 | C37H44ClNO4 602.203 g/mol |  |
| Tremorgenic mycotoxins exert their toxic effects by interfering with neurotransmitter release, possibly by causing degeneration of nerve terminals. They are thought to...more Number of Targets: 27 |
| T3D3735 | Dicumarol 66-76-2 | C19H12O6 336.295 g/mol |  |
| Dicoumarol is an anticoagulant that competitively inhibits vitamin K, preventing the formation of prothrombin. It does this by inhibiting the enzyme NAD(P)H:quinone ox...more Number of Targets: 7 |
| T3D3736 | Cyclopiazonic acid 18172-33-3 | C20H20N2O3 336.384 g/mol |  |
| Cyclopiazonic acid is potent and specific inhibitor of the endoplasmic and sarcoplasmic reticulum Ca+-dependent ATPases, which are essential for calcium reuptake in th...more Number of Targets: 9 |
| T3D3737 | Citreoviridin A 25425-12-1 | C23H30O6 402.481 g/mol |  |
| Citreoviridin inhibits both membrane-bound and soluble mitochondrial ATPases. In particular, it inhibits synaptosomal Na+/K+-ATPase, altering synaptic transmission, an...more Number of Targets: 15 |
| T3D3738 | Penicillic acid 90-65-3 | C8H10O4 170.163 g/mol |  |
| Penicillic acid has been shown to inhibit alcohol and lactate dehydrogenases by forming covalent adducts with either cysteine or lysine residues at the enzyme active s...more Number of Targets: 9 |
| T3D3740 | Beauvericin 26048-05-5 | C45H57N3O9 783.949 g/mol |  |
| Beauvericin is cytotoxic and increases ion permeability in cell membranes by forming complexes with essential cations (Ca2+, Na+, K+) and by forming cation-selective c...more Number of Targets: 3 |
| T3D3741 | Fusaric Acid 536-69-6 | C10H13NO2 179.216 g/mol |  |
| Fusaric acid affects neurotransmitter levels by acting as a partial inhibitor on tyrosine-hydroxylase and an inhibitor on dopamine-beta-hydroxylase. This has been show...more Number of Targets: 3 |