Browsing Toxins By Category
Displaying toxin 1851 - 1875 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D0963 | Dipropylcarbamothioic acid S-ethyl ester 759-94-4 | C9H19NOS 189.318 g/mol |  |
| Some thiocarbamates (EPTC, Molinate, Pebulate, and Cycloate) share a common mechanism of toxicity, i.e. the inhibition of acetylcholinesterase. An acetylcholinesterase...more Number of Targets: 7 |
| T3D4498 | Diquat dibromide 85-00-7 | C12H12Br2N2 344.045 g/mol |  |
| Not Available Number of Targets: 17 |
| T3D2636 | Disintegrin echistatin (Echis carinatus) Not Available | Not Available 5424.090 g/mol |  |
| Disintegrins work by countering blood clotting steps, inhibiting the clumping of platelets. They inhibit fibrinogen interaction with platelet receptors expressed on gl...more Number of Targets: 2 |
| T3D4862 | Disodium 6-hydroxy-5-[(4-sulfophenyl)azo]-2-naphthalenesulfonate 2783-94-0 | C16H12N2Na2O7S2 454.384 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D2557 | Disulfiram 97-77-8 | C10H20N2S4 296.539 g/mol |  |
| Disulfiram blocks the oxidation of alcohol at the acetaldehyde stage during alcohol metabolism following disulfiram intake causing an accumulation of acetaldehyde in t...more Number of Targets: 24 |
| T3D0038 | Disulfoton 298-04-4 | C8H19O2PS3 274.404 g/mol |  |
| Disulfoton is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholineste...more Number of Targets: 6 |
| T3D4499 | Dithiopyr 97886-45-8 | C15H16F5NO2S2 401.415 g/mol |  |
| Not Available Number of Targets: 18 |
| T3D3656 | Ditridecyl phthalate 119-06-2 | C34H58O4 530.822 g/mol |  |
| Phthalate esters are endocrine disruptors. They decrease foetal testis testosterone production and reduce the expression of steroidogenic genes by decreasing mRNA expr...more Number of Targets: 0 |
| T3D3657 | Diundecyl phthalate 3648-20-2 | C30H50O4 474.716 g/mol |  |
| Phthalate esters are endocrine disruptors. They decrease foetal testis testosterone production and reduce the expression of steroidogenic genes by decreasing mRNA expr...more Number of Targets: 0 |
| T3D4500 | Diuron 330-54-1 | C9H10Cl2N2O 233.095 g/mol |  |
| Diuron has been reported to bind to androgen receptors. This suggests that diuron may block the receptors and result in the toxicity on the reproductive system. Number of Targets: 8 |
| T3D3079 | Djenkolic acid 498-59-9 | C7H14N2O4S2 254.327 g/mol |  |
| The toxicity of djenkolic acid in humans arises from its poor solubility under acidic conditions after consumption of the jenkol bean. The amino acid precipitates into...more Number of Targets: 0 |
| T3D3501 | Docetaxel 114977-28-5 | C43H53NO14 807.879 g/mol |  |
| Docetaxel interferes with the normal function of microtubule growth. Whereas drugs like colchicine cause the depolymerization of microtubules in vivo, docetaxel arrest...more Number of Targets: 9 |
| T3D4596 | Dodecanoic acid 143-07-7 | C12H24O2 200.318 g/mol |  |
| Not Available Number of Targets: 13 |
| T3D4904 | Dodecyl gallate 1166-52-5 | C19H30O5 338.439 g/mol |  |
| Not Available Number of Targets: 4 |
| T3D4040 | Domoic acid 14277-97-5 | C15H21NO6 311.330 g/mol |  |
| Domoic acid acts as a neurotoxin. It induces excitotoxicity by an integrative action on ionotropic glutamate receptors at both sides of the synapse for which it has hi...more Number of Targets: 1 |
| T3D2910 | Donepezil 120014-06-4 | C24H29NO3 379.492 g/mol |  |
| Donepezil is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholinester...more Number of Targets: 4 |
| T3D4300 | Dopamine 51-61-6 | C8H11NO2 153.178 g/mol |  |
| Dopamine is a precursor to norepinephrine in noradrenergic nerves and is also a neurotransmitter in certain areas of the central nervous system. Dopamine produces posi...more Number of Targets: 15 |
| T3D4646 | Doxefazepam 40762-15-0 | C17H14ClFN2O3 348.756 g/mol |  |
| Benzodiazepines bind nonspecifically to benzodiazepine receptors BNZ1, which mediates sleep, and BNZ2, which affects affects muscle relaxation, anticonvulsant activity...more Number of Targets: 18 |
| T3D2993 | Doxepin 1668-19-5 | C19H21NO 279.376 g/mol |  |
| The mechanism of action of doxepin is not completely understood. It is thought that like amitriptyline, doxepin enhances the actions of norepinephrine and serotonin by...more Number of Targets: 23 |
| T3D2953 | Doxorubicin 23214-92-8 | C27H29NO11 543.519 g/mol |  |
| Doxorubicin has antimitotic and cytotoxic activity through a number of proposed mechanisms of action: Doxorubicin forms complexes with DNA by intercalation between bas...more Number of Targets: 14 |
| T3D3950 | Doxycycline 564-25-0 | C22H24N2O8 444.435 g/mol |  |
| Tetracyclines target the 28S small subunit of the mitochondrial ribosome thereby deactivation mitochondrial protein synthesis. As a result tetracyclines are cytotoxic ...more Number of Targets: 3 |
| T3D4551 | Doxylamine 469-21-6 | C17H22N2O 270.369 g/mol |  |
| Like other antihistamines, doxylamine acts by competitively inhibiting histamine at H1 receptors. It also has substantial sedative and anticholinergic effects. Number of Targets: 3 |
| T3D2917 | Drostanolone 58-19-5 | C20H32O2 304.467 g/mol |  |
| Dromostanolone is a synthetic androgenic anabolic steroid and is approximately 5 times as potent as natural methyltestosterone. Like testosterone and other androgenic ...more Number of Targets: 4 |
| T3D2805 | Duloxetine 136434-34-9 | C18H19NOS 297.415 g/mol |  |
| Duloxetine is a potent inhibitor of neuronal serotonin and norepinephrine reuptake and a less potent inhibitor of dopamine reuptake. Duloxetine has no significant affi...more Number of Targets: 3 |
| T3D2992 | Econazole 27220-47-9 | C18H15Cl3N2O 381.684 g/mol |  |
| Econazole interacts with 14-α demethylase, a cytochrome P-450 enzyme necessary to convert lanosterol to ergosterol. As ergosterol is an essential component of the fung...more Number of Targets: 4 |