Browsing Toxins By Category
Displaying toxin 3001 - 3025 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D3912 | Prosulfuron 94125-34-5 | C15H16F3N5O4S 419.379 g/mol |  |
| Not Available Number of Targets: 12 |
| T3D2593 | Protective antigen 643772-15-0 | Not Available 85810.325 g/mol |  |
| After binding to a host cell surface receptor, PA is cleaved by membrane endoproteases of the furin family. Cleaved PA molecules assemble into heptamers, which then as...more Number of Targets: 7 |
| T3D4015 | Protopine 130-86-9 | C20H19NO5 353.369 g/mol |  |
| Protopine has been found to inhibit histamine H1 receptors and platelet aggregation, and acts as an analgesic. It is one of the compounds with activity like OPIATE ALK...more Number of Targets: 0 |
| T3D4440 | Protoporphyrin IX 553-12-8 | C34H34N4O4 562.658 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D4439 | Protoporphyrinogen IX 7412-77-3 | C34H40N4O4 568.706 g/mol |  |
| Not Available Number of Targets: 0 |
| T3D2759 | Protriptyline 438-60-8 | C19H21N 263.377 g/mol |  |
| Protriptyline acts by decreasing the reuptake of norepinephrine and serotonin (5-HT). Number of Targets: 4 |
| T3D1004 | Proximphan 2828-42-4 | C10H12N2O2 192.215 g/mol |  |
| Proximphan is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoylation of the active sites...more Number of Targets: 2 |
| T3D4618 | Prunasin 99-18-3 | C14H17NO6 295.288 g/mol |  |
| Organic nitriles decompose into cyanide ions both in vivo and in vitro. Consequently the primary mechanism of toxicity for organic nitriles is their production of toxi...more Number of Targets: 0 |
| T3D2640 | Pseudechetoxin Not Available | Not Available 26474.445 g/mol |  |
| Pseudechetoxin blocks olfactory and retinal cyclic nucleotide-gated (CNG) ion channel currents. It forms high-affinity contacts with the pore turret region and most li...more Number of Targets: 2 |
| T3D4555 | Pseudoephedrine 90-82-4 | C10H15NO 165.232 g/mol |  |
| Pseudoephedrine acts directly on both alpha- and, to a lesser degree, beta-adrenergic receptors. Through direct action on alpha-adrenergic receptors in the mucosa of t...more Number of Targets: 12 |
| T3D2458 | Psilocin 520-53-6 | C12H16N2O 204.268 g/mol |  |
| Psilocin acts as a partial agonist at the 5-HT2A serotonin receptor in the brain where it mimics the effects of serotonin (5-HT). It is an 5-HT1A and 5-HT2A/2C agonist...more Number of Targets: 3 |
| T3D2457 | Psilocybin 520-52-5 | C12H17N2O4P 284.248 g/mol |  |
| Psilocybin is rapidly dephosphorylated in the body to psilocin which then acts as a partial agonist at the 5-HT2A serotonin receptor in the brain where it mimics the e...more Number of Targets: 3 |
| T3D0825 | Psoralen 66-97-7 | C11H6O3 186.164 g/mol |  |
| The mechanism of action many furocoumarins is based on their ability to form photoadducts with DNA and other cellular components such as RNA, proteins, and several pro...more Number of Targets: 4 |
| T3D2849 | Pteroyl-D-glutamic acid 1492-18-8 | C20H23N7O7 473.439 g/mol |  |
| As leucovorin is a derivative of folic acid, it can be used to increase levels of folic acid under conditions favoring folic acid inhibition (following treatment of fo...more Number of Targets: 1 |
| T3D2529 | Pumiliotoxin 73376-35-9 | C16H29NO 251.408 g/mol |  |
| Pumiliotoxin affects voltage-gated calcium channels, interfering with muscle contraction in the heart and skeletal muscle. They also may block sodium and potassium cha...more Number of Targets: 25 |
| T3D4169 | Putrescine 110-60-1 | C4H12N2 88.152 g/mol |  |
| Uremic toxins such as putrescine are actively transported into the kidneys via organic ion transporters (especially OAT3). Increased levels of uremic toxins can stimul...more Number of Targets: 7 |
| T3D3913 | Pymetrozine 123312-89-0 | C10H11N5O 217.227 g/mol |  |
| Not Available Number of Targets: 3 |
| T3D3914 | Pyraclostrobin 175013-18-0 | C19H18ClN3O4 387.817 g/mol |  |
| Not Available Number of Targets: 48 |
| T3D4531 | Pyraflufen-ethyl 129630-19-9 | C15H13Cl2F3N2O4 413.176 g/mol |  |
| Not Available Number of Targets: 14 |
| T3D0253 | Pyrene 129-00-0 | C16H10 202.251 g/mol |  |
| The ability of PAH's to bind to blood proteins such as albumin allows them to be transported throughout the body. Many PAH's induce the expression of cytochrome P450 e...more Number of Targets: 8 |
| T3D1857 | Pyrethrin I 121-21-1 | C21H28O3 328.445 g/mol |  |
| Pyrethrins exert their effect by prolonging the open phase of the sodium channel gates when a nerve cell is excited. They appear to bind to the membrane lipid phase in...more Number of Targets: 20 |
| T3D1858 | Pyrethrin II 121-29-9 | C22H28O5 372.455 g/mol |  |
| Pyrethrins exert their effect by prolonging the open phase of the sodium channel gates when a nerve cell is excited. They appear to bind to the membrane lipid phase in...more Number of Targets: 21 |
| T3D0233 | Pyrethrum 8003-34-7 | C22H28O5 372.455 g/mol |  |
| Both type I and type II pyrethroids exert their effect by prolonging the open phase of the sodium channel gates when a nerve cell is excited. They appear to bind to th...more Number of Targets: 20 |
| T3D3915 | Pyridaben 96489-71-3 | C19H25ClN2OS 364.933 g/mol |  |
| Not Available Number of Targets: 28 |
| T3D0707 | Pyridinium chlorochromate 26299-14-9 | C5H6ClCrNO3 215.555 g/mol |  |
| Hexavalent chromium's carcinogenic effects are caused by its metabolites, pentavalent and trivalent chromium. The DNA damage may be caused by hydroxyl radicals produce...more Number of Targets: 6 |