Browsing Toxins
Displaying toxin 2151 - 2175 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D2645 | Brevetoxin 98112-41-5 | C49H68O14 881.056 g/mol |  |
| Brevetoxins are neurotoxins that bind to voltage-gated sodium channels in nerve cells, leading to disruption of normal neurological processes. (L1112) Number of Targets: 14 |
| T3D2646 | Hydralysin (Chlorohydra viridissima) Not Available | Not Available 26212.075 g/mol |  |
| Hydralysin is a cytolytic toxin. It binds to erythrocyte membranes and has weak hemolytic activity, probably mediated by oligomerization and pore formation. (T170) Number of Targets: 0 |
| T3D2647 | Stonustoxin Not Available | Not Available 79523.640 g/mol | |
| Stonustoxin induces hemolytic activities due to its ability to form pores in the cell membrane. It is also myotoxic and interferes irreversibly with neuromuscular func...more Number of Targets: 0 |
| T3D2648 | Neoverrucotoxin Not Available | Not Available 79669.850 g/mol | |
| Neoverrucotoxin has hemolytic activities. (T170) Number of Targets: 0 |
| T3D2649 | Box jellyfish toxin (Chironex fleckeri) Not Available | Not Available 51389.865 g/mol | |
| Box jellyfish toxin has potent hemolytic activity and may act as a pore-forming toxin, disrupting normal transmembrane ion concentration gradients in susceptible cells...more Number of Targets: 0 |
| T3D2656 | omega-Conotoxin (Conus striatus) Not Available | Not Available 7628.040 g/mol |  |
| omega-Conotoxins act at presynaptic membranes, where they bind inhibit N-type voltage-dependent calcium channels. (L1107) Number of Targets: 1 |
| T3D2657 | alpha-Conotoxin (Conus geographus) Not Available | Not Available 1627.830 g/mol |  |
| alpha-Conotoxins act on postsynaptic membranes, where they inhibit nicotinic acetylcholine receptors in nerves and muscles. (L1107) Number of Targets: 15 |
| T3D2658 | delta-Conotoxin (Conus striatus) Not Available | Not Available 9216.755 g/mol |  |
| delta-Conotoxins inhibit the inactivation of voltage-dependent sodium channels. (L1107) Number of Targets: 14 |
| T3D2659 | kappa-Conotoxin (Conus purpurascens) Not Available | Not Available 8316.795 g/mol |  |
| kappa-Conotoxins inhibit potassium channels. (L1107) Number of Targets: 23 |
| T3D2660 | mu-Conotoxin (Conus purpurascens) Not Available | Not Available 8333.700 g/mol |  |
| mu-Conotoxins inhibit voltage-dependent sodium channels in muscles. (L1107) Number of Targets: 14 |
| T3D2661 | Contryphan (Conus ventricosus) Not Available | Not Available 1091.260 g/mol |  |
| Contryphan affects both voltage-gated and calcium-dependent potassium channels. (L1108) Number of Targets: 32 |
| T3D2663 | Clodronate 10596-23-3 | CH4Cl2O6P2 244.892 g/mol |  |
| The bisphosphonate group binds strongly to the bone mineral, hydroxyapatite. This explains the specific pharmacological action of these compounds on mineralized tissue...more Number of Targets: 9 |
| T3D2665 | Pamidronate 40391-99-9 | C3H11NO7P2 235.070 g/mol |  |
| The mechanism of action of pamidronate is inhibition of bone resorption. Pamidronate adsorbs to calcium phosphate (hydroxyapatite) crystals in bone and may directly bl...more Number of Targets: 3 |
| T3D2666 | Alendronic acid 66376-36-1 | C4H13NO7P2 249.096 g/mol |  |
| The action of Alendronate on bone tissue is based partly on its affinity for hydroxyapatite, which is part of the mineral matrix of bone. Alendronate also targets farn...more Number of Targets: 7 |
| T3D2667 | Ibandronate 114084-78-5 | C9H23NO7P2 319.229 g/mol |  |
| The action of ibandronate on bone tissue is based partly on its affinity for hydroxyapatite, which is part of the mineral matrix of bone. Nitrogen-containing bisphosph...more Number of Targets: 3 |
| T3D2668 | Risedronate 105462-24-6 | C7H11NO7P2 283.112 g/mol |  |
| The action of risedronate on bone tissue is based partly on its affinity for hydroxyapatite, which is part of the mineral matrix of bone. Risedronate also targets farn...more Number of Targets: 3 |
| T3D2669 | Zoledronate 118072-93-8 | C5H10N2O7P2 272.090 g/mol |  |
| The action of zoledronate on bone tissue is based partly on its affinity for hydroxyapatite, which is part of the mineral matrix of bone. Zoledronate also targets farn...more Number of Targets: 4 |
| T3D2670 | Digoxin 20830-75-5 | C41H64O14 780.939 g/mol |  |
| Digoxin binds to a site on the extracellular aspect of the alpha-subunit of the Na+/K+ ATPase pump in the membranes of heart cells (myocytes) and decreases its functio...more Number of Targets: 17 |
| T3D2671 | Rituximab 174722-31-7 | Not Available 36105.695 g/mol |  |
| Binds to the CD20 antigen which is found on mature B lymphocytes. The Fc domain recruits immune effector functions to mediate B-cell lysis. The antibody appears to ind...more Number of Targets: 12 |
| T3D2672 | Azaspiracid 214899-21-5 | C47H71NO12 842.066 g/mol |  |
| Azaspiracid-4 dose-dependent inhibits the increase in cytosolic Ca2+ levels induced by thapsigargin (Tg) (A330). Azaspiracid-2 and Azaspiracid-3 clearly increase cytos...more Number of Targets: 1 |
| T3D2673 | Zaleplon 151319-34-5 | C17H15N5O 305.334 g/mol |  |
| Zaleplon exerts its action through subunit modulation of the GABABZ receptor chloride channel macromolecular complex. Zaleplon also binds selectively to the brain omeg...more Number of Targets: 2 |
| T3D2674 | Oxaliplatin 61825-94-3 | C8H12N2O4Pt 395.276 g/mol |  |
| Oxaliplatin undergoes nonenzymatic conversion to active derivatives via displacement of the labile oxalate ligand. Several transient reactive species are formed, inclu...more Number of Targets: 1 |
| T3D2675 | Linezolid 165800-03-3 | C16H20FN3O4 337.346 g/mol |  |
| Linezolid targets the large 39S subunit of the mitochondrial ribosome thereby deactivation mitochondrial protein synthesis. As a result Linezolid is cytotoxic to the m...more Number of Targets: 6 |
| T3D2676 | Methadone 76-99-3 | C21H27NO 309.445 g/mol |  |
| Methadone is a mu-agonist; a synthetic opioid analgesic with multiple actions qualitatively similar to those of morphine, the most prominent of which involves the cent...more Number of Targets: 10 |
| T3D2677 | Aripiprazole 129722-12-9 | C23H27Cl2N3O2 448.385 g/mol |  |
| Aripiprazole's antipsychotic activity is likely due to a combination of antagonism at D2 receptors in the mesolimbic pathway and 5HT2A receptors in the frontal cortex....more Number of Targets: 41 |