Displaying toxin 2151 - 2175 of 3678 in total
T3DB ID Name
CAS Number
Formula
Weight
StructureTypeMechanism of Toxicity
T3D2645Brevetoxin
98112-41-5
C49H68O14
881.056 g/mol
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  • Aldehyde
  • Animal Toxin
  • Ester
  • Ether
  • Marine Toxin
  • Natural Compound
  • Organic Compound
Brevetoxins are neurotoxins that bind to voltage-gated sodium channels in nerve cells, leading to disruption of normal neurological processes. (L1112)
Number of Targets: 14
T3D2646Hydralysin (Chlorohydra viridissima)
Not Available
Not Available
26212.075 g/mol
No structure small
  • Amide
  • Amine
  • Animal Toxin
  • Marine Toxin
  • Natural Compound
  • Organic Compound
  • Protein
Hydralysin is a cytolytic toxin. It binds to erythrocyte membranes and has weak hemolytic activity, probably mediated by oligomerization and pore formation. (T170)
Number of Targets: 0
T3D2647Stonustoxin
Not Available
Not Available
79523.640 g/mol
No structure small
  • Amide
  • Amine
  • Animal Toxin
  • Marine Toxin
  • Natural Compound
  • Organic Compound
  • Protein
Stonustoxin induces hemolytic activities due to its ability to form pores in the cell membrane. It is also myotoxic and interferes irreversibly with neuromuscular func...more
Number of Targets: 0
T3D2648Neoverrucotoxin
Not Available
Not Available
79669.850 g/mol
No structure small
  • Amide
  • Amine
  • Animal Toxin
  • Marine Toxin
  • Natural Compound
  • Organic Compound
  • Protein
Neoverrucotoxin has hemolytic activities. (T170)
Number of Targets: 0
T3D2649Box jellyfish toxin (Chironex fleckeri)
Not Available
Not Available
51389.865 g/mol
No structure small
  • Amide
  • Amine
  • Animal Toxin
  • Marine Toxin
  • Natural Compound
  • Organic Compound
  • Protein
Box jellyfish toxin has potent hemolytic activity and may act as a pore-forming toxin, disrupting normal transmembrane ion concentration gradients in susceptible cells...more
Number of Targets: 0
T3D2656omega-Conotoxin (Conus striatus)
Not Available
Not Available
7628.040 g/mol
T3d2656
  • Amide
  • Amine
  • Animal Toxin
  • Natural Compound
  • Organic Compound
  • Protein
  • Snail Toxin
omega-Conotoxins act at presynaptic membranes, where they bind inhibit N-type voltage-dependent calcium channels. (L1107)
Number of Targets: 1
T3D2657alpha-Conotoxin (Conus geographus)
Not Available
Not Available
1627.830 g/mol
T3d2657
  • Amide
  • Amine
  • Animal Toxin
  • Natural Compound
  • Organic Compound
  • Protein
  • Snail Toxin
alpha-Conotoxins act on postsynaptic membranes, where they inhibit nicotinic acetylcholine receptors in nerves and muscles. (L1107)
Number of Targets: 15
T3D2658delta-Conotoxin (Conus striatus)
Not Available
Not Available
9216.755 g/mol
T3d2658
  • Amide
  • Amine
  • Animal Toxin
  • Natural Compound
  • Organic Compound
  • Protein
  • Snail Toxin
delta-Conotoxins inhibit the inactivation of voltage-dependent sodium channels. (L1107)
Number of Targets: 14
T3D2659kappa-Conotoxin (Conus purpurascens)
Not Available
Not Available
8316.795 g/mol
T3d2659
  • Amide
  • Amine
  • Animal Toxin
  • Natural Compound
  • Organic Compound
  • Protein
  • Snail Toxin
kappa-Conotoxins inhibit potassium channels. (L1107)
Number of Targets: 23
T3D2660mu-Conotoxin (Conus purpurascens)
Not Available
Not Available
8333.700 g/mol
T3d2660
  • Amide
  • Amine
  • Animal Toxin
  • Natural Compound
  • Organic Compound
  • Protein
  • Snail Toxin
mu-Conotoxins inhibit voltage-dependent sodium channels in muscles. (L1107)
Number of Targets: 14
T3D2661Contryphan (Conus ventricosus)
Not Available
Not Available
1091.260 g/mol
T3d2661
  • Amide
  • Amine
  • Animal Toxin
  • Natural Compound
  • Organic Compound
  • Protein
  • Snail Toxin
Contryphan affects both voltage-gated and calcium-dependent potassium channels. (L1108)
Number of Targets: 32
T3D2663Clodronate
10596-23-3
CH4Cl2O6P2
244.892 g/mol
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  • Antihypocalcemic Agent
  • Antineoplastic Agent
  • Bisphosphonate
  • Bone Density Conservation Agent
  • Drug
  • Metabolite
  • Organic Compound
  • Organochloride
  • Osteoporosis Prophylactic
  • Synthetic Compound
The bisphosphonate group binds strongly to the bone mineral, hydroxyapatite. This explains the specific pharmacological action of these compounds on mineralized tissue...more
Number of Targets: 9
T3D2665Pamidronate
40391-99-9
C3H11NO7P2
235.070 g/mol
Thumb
  • Amine
  • Anti-Inflammatory Agent
  • Antineoplastic Agent
  • Bisphosphonate
  • Bone Density Conservation Agent
  • Drug
  • Metabolite
  • Organic Compound
  • Synthetic Compound
The mechanism of action of pamidronate is inhibition of bone resorption. Pamidronate adsorbs to calcium phosphate (hydroxyapatite) crystals in bone and may directly bl...more
Number of Targets: 3
T3D2666Alendronic acid
66376-36-1
C4H13NO7P2
249.096 g/mol
Thumb
  • Amine
  • Antihypocalcemic Agent
  • Antiresorptive
  • Bisphosphonate
  • Bone Density Conservation Agent
  • Drug
  • Food Toxin
  • Metabolite
  • Organic Compound
  • Synthetic Compound
The action of Alendronate on bone tissue is based partly on its affinity for hydroxyapatite, which is part of the mineral matrix of bone. Alendronate also targets farn...more
Number of Targets: 7
T3D2667Ibandronate
114084-78-5
C9H23NO7P2
319.229 g/mol
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  • Amine
  • Antihypocalcemic Agent
  • Antiresorptive
  • Bisphosphonate
  • Bone Density Conservation Agent
  • Drug
  • Metabolite
  • Organic Compound
  • Synthetic Compound
The action of ibandronate on bone tissue is based partly on its affinity for hydroxyapatite, which is part of the mineral matrix of bone. Nitrogen-containing bisphosph...more
Number of Targets: 3
T3D2668Risedronate
105462-24-6
C7H11NO7P2
283.112 g/mol
Thumb
  • Antihypocalcemic Agent
  • Antiresorptive
  • Bisphosphonate
  • Bone Density Conservation Agent
  • Calcium Channel Blocker
  • Drug
  • Metabolite
  • Organic Compound
  • Synthetic Compound
The action of risedronate on bone tissue is based partly on its affinity for hydroxyapatite, which is part of the mineral matrix of bone. Risedronate also targets farn...more
Number of Targets: 3
T3D2669Zoledronate
118072-93-8
C5H10N2O7P2
272.090 g/mol
Thumb
  • Antihypocalcemic Agent
  • Antiresorptive
  • Bisphosphonate
  • Bone Density Conservation Agent
  • Drug
  • Metabolite
  • Organic Compound
  • Synthetic Compound
The action of zoledronate on bone tissue is based partly on its affinity for hydroxyapatite, which is part of the mineral matrix of bone. Zoledronate also targets farn...more
Number of Targets: 4
T3D2670Digoxin
20830-75-5
C41H64O14
780.939 g/mol
Thumb
  • Anti-Arrhythmia Agent
  • Cardiotonic Agent
  • Drug
  • Enzyme Inhibitor
  • Ester
  • Food Toxin
  • Metabolite
  • Natural Compound
  • Organic Compound
  • Plant Toxin
Digoxin binds to a site on the extracellular aspect of the alpha-subunit of the Na+/K+ ATPase pump in the membranes of heart cells (myocytes) and decreases its functio...more
Number of Targets: 17
T3D2671Rituximab
174722-31-7
Not Available
36105.695 g/mol
T3d2671
  • Amide
  • Amine
  • Animal Toxin
  • Antineoplastic Agent
  • Antirheumatic Agent
  • Immunologic Factor
  • Organic Compound
  • Protein
  • Synthetic Compound
Binds to the CD20 antigen which is found on mature B lymphocytes. The Fc domain recruits immune effector functions to mediate B-cell lysis. The antibody appears to ind...more
Number of Targets: 12
T3D2672Azaspiracid
214899-21-5
C47H71NO12
842.066 g/mol
Thumb
  • Amine
  • Animal Toxin
  • Ether
  • Food Toxin
  • Marine Toxin
  • Metabolite
  • Organic Compound
  • Synthetic Compound
Azaspiracid-4 dose-dependent inhibits the increase in cytosolic Ca2+ levels induced by thapsigargin (Tg) (A330). Azaspiracid-2 and Azaspiracid-3 clearly increase cytos...more
Number of Targets: 1
T3D2673Zaleplon
151319-34-5
C17H15N5O
305.334 g/mol
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  • Amide
  • Amine
  • Anticonvulsant
  • Anxiolytic
  • Drug
  • Hypnotic and Sedative
  • Metabolite
  • Nitrile
  • Organic Compound
  • Synthetic Compound
Zaleplon exerts its action through subunit modulation of the GABABZ receptor chloride channel macromolecular complex. Zaleplon also binds selectively to the brain omeg...more
Number of Targets: 2
T3D2674Oxaliplatin
61825-94-3
C8H12N2O4Pt
395.276 g/mol
Thumb
  • Antineoplastic Agent
  • Drug
  • Metabolite
  • Organic Compound
  • Synthetic Compound
Oxaliplatin undergoes nonenzymatic conversion to active derivatives via displacement of the labile oxalate ligand. Several transient reactive species are formed, inclu...more
Number of Targets: 1
T3D2675Linezolid
165800-03-3
C16H20FN3O4
337.346 g/mol
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  • Amide
  • Amine
  • Anti-Bacterial Agent
  • Anti-Infective Agent
  • Drug
  • Ester
  • Ether
  • Metabolite
  • Organic Compound
  • Organofluoride
  • Protein Synthesis Inhibitor
  • Synthetic Compound
Linezolid targets the large 39S subunit of the mitochondrial ribosome thereby deactivation mitochondrial protein synthesis. As a result Linezolid is cytotoxic to the m...more
Number of Targets: 6
T3D2676Methadone
76-99-3
C21H27NO
309.445 g/mol
Thumb
  • Amine
  • Analgesic
  • Analgesic, Opioid
  • Antitussive Agent
  • Drug
  • Metabolite
  • Narcotic
  • Opiate Agonist
  • Organic Compound
  • Synthetic Compound
Methadone is a mu-agonist; a synthetic opioid analgesic with multiple actions qualitatively similar to those of morphine, the most prominent of which involves the cent...more
Number of Targets: 10
T3D2677Aripiprazole
129722-12-9
C23H27Cl2N3O2
448.385 g/mol
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  • Amide
  • Amine
  • Antipsychotic Agent
  • Drug
  • Ether
  • Food Toxin
  • Metabolite
  • Organic Compound
  • Organochloride
  • Synthetic Compound
Aripiprazole's antipsychotic activity is likely due to a combination of antagonism at D2 receptors in the mesolimbic pathway and 5HT2A receptors in the frontal cortex....more
Number of Targets: 41
Displaying toxin 2151 - 2175 of 3678 in total