Browsing Toxins
Displaying toxin 2476 - 2500 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D3084 | Resiniferatoxin 57444-62-9 | C37H40O9 628.708 g/mol |  |
| Resiniferatoxin activates the vanilloid receptor in a subpopulation of primary afferent sensory neurons involved in nociception (the transmission of physiological pain...more Number of Targets: 1 |
| T3D3085 | Capsaicin 404-86-4 | C18H27NO3 305.412 g/mol |  |
| The burning and painful sensations associated with capsaicin result from its chemical interaction with sensory neurons. Capsaicin, as a member of the vanilloid family,...more Number of Targets: 5 |
| T3D3086 | Strychnine 57-24-9 | C21H22N2O2 334.412 g/mol |  |
| Strychnine acts as an antagonist at the inhibitory or strychnine-sensitive glycine receptor, a ligand-gated chloride channel in the spinal cord and the brain. (L1230) Number of Targets: 8 |
| T3D3087 | Swainsonine 72741-87-8 | C8H15NO3 173.210 g/mol |  |
| Swainsonine inhibits the activity of glycoside hydrolases, especially N-linked glycosylation. Inhibition of Golgi mannosidase II and other alpha-mannosidases causes th...more Number of Targets: 10 |
| T3D3088 | Thionin (Pyrularia pubera) Not Available | Not Available 5288.110 g/mol |  |
| Thionins are thought to attack the cell membrane and render it permeable. This results in the inhibition of sugar uptake and allows potassium and phosphate ions, prote...more Number of Targets: 0 |
| T3D3089 | Tutin 2571-22-4 | C15H18O6 294.300 g/mol |  |
| Tutin is a potent antagonist of the glycine receptor. (L1250) Number of Targets: 5 |
| T3D3090 | Grayanotoxin I 4720-09-6 | C22H36O7 412.517 g/mol |  |
| Grayanotoxins bind to specific sodium ion channels in cell membranes. The grayanotoxins prevent inactivation, leaving excitable cells depolarized. (L1251) Number of Targets: 14 |
| T3D3091 | Grayanotoxin II 4678-44-8 | C20H32O5 352.465 g/mol |  |
| Grayanotoxins bind to specific sodium ion channels in cell membranes. The grayanotoxins prevent inactivation, leaving excitable cells depolarized. (L1251) Number of Targets: 14 |
| T3D3092 | Grayanotoxin III 4678-45-9 | C20H34O6 370.480 g/mol |  |
| Grayanotoxins bind to specific sodium ion channels in cell membranes. The grayanotoxins prevent inactivation, leaving excitable cells depolarized. (L1251) Number of Targets: 14 |
| T3D3094 | Oleandrin 465-16-7 | C32H48O9 576.718 g/mol |  |
| Oleandrin likely exerts its toxic effects by inhibiting Na+,K+-ATPase. (A2831) Number of Targets: 9 |
| T3D3095 | Hyoscyamine 101-31-5 | C17H23NO3 289.369 g/mol |  |
| Hyoscyamine is an anticholinergic, specifically an antimuscarinic, and works by blocking the action of acetylcholine at parasympathetic sites in smooth muscle, secreto...more Number of Targets: 5 |
| T3D3096 | D-Hyoscyamine 13269-35-7 | C17H23NO3 289.369 g/mol |  |
| Hyoscyamine is an anticholinergic, specifically an antimuscarinic, and works by blocking the action of acetylcholine at parasympathetic sites in smooth muscle, secreto...more Number of Targets: 6 |
| T3D3097 | Tubocurarine 6989-98-6 | C37H41N2O6 609.731 g/mol |  |
| Tubocurarine is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholines...more Number of Targets: 21 |
| T3D3098 | Alcuronium 23214-96-2 | C44H50Br2N4O2 826.701 g/mol |  |
| Curare is a non-depolarizing muscle relaxant that acts as a competitive antagonist at the nicotinic acetylcholine receptors. (L1256) Number of Targets: 17 |
| T3D3099 | Toxiferine 6888-23-9 | C40H46Cl2N4O2 685.725 g/mol |  |
| Curare is a non-depolarizing muscle relaxant that acts as a competitive antagonist at the nicotinic acetylcholine receptors. (L1256) Number of Targets: 16 |
| T3D3101 | Brodifacoum 56073-10-0 | C31H23BrO3 523.417 g/mol |  |
| Brodifacoum inhibits the enzyme Vitamin K epoxide reductase. This enzyme is needed for the reconstitution of the vitamin K in its cycle from vitamin K-epoxide, and so ...more Number of Targets: 1 |
| T3D3102 | Bromadiolone 28772-56-7 | C30H23BrO4 527.405 g/mol |  |
| Bromadiolone inhibits the enzyme Vitamin K epoxide reductase. This enzyme is needed for the reconstitution of the vitamin K in its cycle from vitamin K-epoxide, and so...more Number of Targets: 1 |
| T3D3103 | Fumarin 117-52-2 | C17H14O5 298.290 g/mol |  |
| Fumarin inhibits the enzyme Vitamin K epoxide reductase. This enzyme is needed for the reconstitution of the vitamin K in its cycle from vitamin K-epoxide, and so fuma...more Number of Targets: 1 |
| T3D3104 | Difenacoum 56073-07-5 | C31H24O3 444.521 g/mol |  |
| Difenacoum inhibits the enzyme Vitamin K epoxide reductase. This enzyme is needed for the reconstitution of the vitamin K in its cycle from vitamin K-epoxide, and so d...more Number of Targets: 1 |
| T3D3105 | Phenprocoumon 435-97-2 | C18H16O3 280.318 g/mol |  |
| Phenprocoumon inhibits vitamin K reductase, resulting in depletion of the reduced form of vitamin K (vitamin KH2). As vitamin K is a cofactor for the carboxylation of ...more Number of Targets: 3 |
| T3D3106 | Acenocoumarol 152-72-7 | C19H15NO6 353.326 g/mol |  |
| Acenocoumarol inhibits vitamin K reductase, resulting in depletion of the reduced form of vitamin K (vitamin KH2). As vitamin K is a cofactor for the carboxylation of ...more Number of Targets: 3 |
| T3D3107 | Phenindione 83-12-5 | C15H10O2 222.239 g/mol |  |
| Phenindione inhibits vitamin K reductase, resulting in depletion of the reduced form of vitamin K (vitamin KH2). As vitamin K is a cofactor for the carboxylation of gl...more Number of Targets: 1 |
| T3D3108 | Anabasine 13078-04-1 | C10H14N2 162.232 g/mol |  |
| Anabasine is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholinester...more Number of Targets: 16 |
| T3D3114 | Myristicin 607-91-0 | C11H12O3 192.211 g/mol |  |
| Myristicin exerts possible neurotoxic effects on dopaminergic neurons and is a weak inhibitor of monoamine oxidase. (L1271) Number of Targets: 2 |
| T3D3121 | Diphtheria toxin (Corynephage omega) Not Available | Not Available 60814.155 g/mol |  |
| Diphtheria toxin consists of a single polypeptide. Proteolysis yields two fragments (A and B) which are held together by a disulfide bond. The toxin binds to EGF-like ...more Number of Targets: 1 |