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Displaying toxin 2026 - 2050 of 3678 in total
T3DB ID Name
CAS Number
Formula
Weight
StructureTypeMechanism of Toxicity
T3D2497Robustoxin
91728-12-0
Not Available
4856.685 g/mol
T3d2497
  • Amide
  • Amine
  • Animal Toxin
  • Natural Compound
  • Organic Compound
  • Protein
  • Spider Toxin
Robustoxin inhibits both insect and mammalian voltage-gated sodium channels. It binds to site 3 in tetrodotoxin-sensitive sodium channels, which slows their inactivati...more
Number of Targets: 14
T3D2498Grammotoxin
152617-90-8
Not Available
9600.980 g/mol
T3d2498
  • Amide
  • Amine
  • Animal Toxin
  • Natural Compound
  • Organic Compound
  • Protein
  • Spider Toxin
Grammotoxin inhibits P-, Q- and N-type voltage-gated calcium channels in neurons. Binding to the calcium channels modifies their voltage-dependent gating. This makes i...more
Number of Targets: 3
T3D2499Huwentoxin
526224-73-7
Not Available
9318.830 g/mol
T3d2499
  • Amide
  • Amine
  • Animal Toxin
  • Natural Compound
  • Organic Compound
  • Protein
  • Spider Toxin
Huwentoxin blocks neuromuscular transmission by binding to the nicotinic acetylcholine receptor, which affects the release of neurotransmitters from autonomic nerve en...more
Number of Targets: 17
T3D2500alpha-Latrotoxin
65988-34-3
Not Available
156855.500 g/mol
T3d2500
  • Amide
  • Amine
  • Animal Toxin
  • Natural Compound
  • Organic Compound
  • Protein
  • Spider Toxin
alpha-Latrotoxin acts presynaptically to release neurotransmitters from sensory and motor neurons, as well as on endocrine cells. alpha-Latrotoxin tetramers can form i...more
Number of Targets: 10
T3D2501Phrixotoxin
880886-00-0 or 221872-97-5
Not Available
3555.310 g/mol
T3d2501
  • Amide
  • Amine
  • Animal Toxin
  • Natural Compound
  • Organic Compound
  • Protein
  • Spider Toxin
Phrixotoxin blocks A-type potassium channels by altering the gating properties of these channels. (T170)
Number of Targets: 2
T3D2502Stromatoxin
1262235-00-6
Not Available
3798.295 g/mol
No structure small
  • Amide
  • Amine
  • Animal Toxin
  • Natural Compound
  • Organic Compound
  • Protein
  • Spider Toxin
Stromatoxin blocks the delayed-rectifier type potassium channels Kv2.1, Kv2.2, Kv2.1/9.3 and the A-type potassium channel Kv4.2, with affinity (IC50) of 12.7 nM, 21.4 ...more
Number of Targets: 4
T3D2503Phoneutriatoxin
Not Available
Not Available
12677.715 g/mol
No structure small
  • Amide
  • Amine
  • Animal Toxin
  • Natural Compound
  • Organic Compound
  • Protein
  • Spider Toxin
Phoneutriatoxin acts as an antagonist at certain calcium channels. (T170)
Number of Targets: 3
T3D2505Heteropodatoxin
189120-72-7
Not Available
3917.380 g/mol
T3d2505
  • Amide
  • Amine
  • Animal Toxin
  • Natural Compound
  • Organic Compound
  • Protein
  • Spider Toxin
Heteropodatoxin blocks A-type, transient voltage-gated potassium channels by acting as a gating modifier. As a result, a larger depolarization is needed to open the ch...more
Number of Targets: 3
T3D2506Agitoxin
155646-21-2
Not Available
4020.835 g/mol
T3d2506
  • Amide
  • Amine
  • Animal Toxin
  • Natural Compound
  • Organic Compound
  • Protein
  • Scorpion Toxin
Agitoxin binds to and blocks the Shaker potassium channel in Drosophila as well as to its mammalian homologue. (A157)
Number of Targets: 8
T3D2507Charybdotoxin
95751-30-7
Not Available
6673.890 g/mol
T3d2507
  • Amide
  • Amine
  • Animal Toxin
  • Natural Compound
  • Organic Compound
  • Protein
  • Scorpion Toxin
Charybdotoxin is a neurotoxin that blocks calcium-activated and voltage gated potassium channels by binding to one of four independent, overlapping binding sites. This...more
Number of Targets: 10
T3D2508Chlorotoxin
163515-35-3
Not Available
4004.725 g/mol
T3d2508
  • Amide
  • Amine
  • Animal Toxin
  • Natural Compound
  • Organic Compound
  • Protein
  • Scorpion Toxin
Chlorotoxin blocks small conductance chloride channels. (L1043)
Number of Targets: 15
T3D2509Cobatoxin
211688-17-4
Not Available
7131.365 g/mol
T3d2509
  • Amide
  • Amine
  • Animal Toxin
  • Natural Compound
  • Organic Compound
  • Protein
  • Scorpion Toxin
Cobatoxin blocks calcium-activated and voltage-gated potassium channels. (L1045)
Number of Targets: 7
T3D2510alpha-Cobratoxin
769933-79-1
Not Available
7830.960 g/mol
T3d2510
  • Amide
  • Amine
  • Animal Toxin
  • Lachrymator
  • Natural Compound
  • Organic Compound
  • Protein
  • Snake Venom
alpha-Cobratoxin is a muscle-type nicotinic acetylcholine receptor (nAChR) antagonist. It causes paralysis by preventing the binding of acetylcholine to the nAChR, as ...more
Number of Targets: 6
T3D2511kappa-Hefutoxin
478621-50-0
Not Available
2659.865 g/mol
T3d2511
  • Amide
  • Amine
  • Animal Toxin
  • Natural Compound
  • Organic Compound
  • Protein
  • Scorpion Toxin
kappa-Hefutoxin blocks voltage-gated potassium channels and also slows down their activation kinetics. (L1048)
Number of Targets: 2
T3D2512Iberiotoxin
129203-60-7
Not Available
4253.920 g/mol
T3d2512
  • Amide
  • Amine
  • Animal Toxin
  • Natural Compound
  • Organic Compound
  • Protein
  • Scorpion Toxin
Iberiotoxin binds to the outer face of the large-conductance calcium-activated potassium channels with high affinity. It selectively inhibits the current by decreasin...more
Number of Targets: 5
T3D2513Imperatoxin-A
172451-37-5
Not Available
3764.370 g/mol
T3d2513
  • Amide
  • Amine
  • Animal Toxin
  • Natural Compound
  • Organic Compound
  • Protein
  • Scorpion Toxin
Imperatoxin-A is an activator which enhances the influx of Ca2+ from the sarcoplasmatic reticulum into the cell. Imperatoxin-A acts on the Ryanodine receptors (RyR), w...more
Number of Targets: 3
T3D2514Imperatoxin-1
Not Available
Not Available
18663.670 g/mol
No structure small
  • Amide
  • Amine
  • Animal Toxin
  • Natural Compound
  • Organic Compound
  • Protein
  • Scorpion Toxin
Imperatoxin-I is an inhibitor which decreases the influx of Ca2+ from the sarcoplasmatic reticulum into the cell. Imperatoxin-I acts on the Ryanodine receptors (RyR), ...more
Number of Targets: 3
T3D2515Kaliotoxin
145199-73-1
Not Available
6461.905 g/mol
T3d2515
  • Amide
  • Amine
  • Animal Toxin
  • Natural Compound
  • Organic Compound
  • Protein
  • Scorpion Toxin
Kaliotoxin is a neurotoxin that binds to voltage-gated and calcium-activated potassium channels. It binds to the extracellular surface and blocks the channel, affectin...more
Number of Targets: 6
T3D2516Kaliotoxin-1
150769-72-5
Not Available
4155.975 g/mol
T3d2516
  • Amide
  • Amine
  • Animal Toxin
  • Natural Compound
  • Organic Compound
  • Protein
  • Scorpion Toxin
Kaliotoxin is a neurotoxin that binds to voltage-gated and calcium-activated potassium channels. It binds to the extracellular surface and blocks the channel, affectin...more
Number of Targets: 6
T3D2517Kaliotoxin-2
159605-22-8
Not Available
6392.840 g/mol
No structure small
  • Amide
  • Amine
  • Animal Toxin
  • Natural Compound
  • Organic Compound
  • Protein
  • Scorpion Toxin
Kaliotoxin is a neurotoxin that binds to voltage-gated and calcium-activated potassium channels. It binds to the extracellular surface and blocks the channel, affectin...more
Number of Targets: 6
T3D2518Kaliotoxin-3
223246-26-2
Not Available
4027.840 g/mol
No structure small
  • Amide
  • Amine
  • Animal Toxin
  • Natural Compound
  • Organic Compound
  • Protein
  • Scorpion Toxin
Kaliotoxin is a neurotoxin that binds to voltage-gated and calcium-activated potassium channels. It binds to the extracellular surface and blocks the channel, affectin...more
Number of Targets: 6
T3D2519Kurtoxin
820959-57-7
Not Available
7394.400 g/mol
T3d2519
  • Amide
  • Amine
  • Animal Toxin
  • Natural Compound
  • Organic Compound
  • Protein
  • Scorpion Toxin
Kurtoxin affects the gating of voltage-gated sodium channels and calcium channels. In calcium channels Kurtoxin binds close to the channel voltage sensor and thereby p...more
Number of Targets: 14
T3D2520Margatoxin
145808-47-5
Not Available
4184.990 g/mol
T3d2520
  • Amide
  • Amine
  • Animal Toxin
  • Natural Compound
  • Organic Compound
  • Protein
  • Scorpion Toxin
Margatoxin blocks potassium channels, resulting in a loss of outward current and affecting neurotransmitter release. (L1057)
Number of Targets: 1
T3D2521Maurotoxin
188240-41-7
Not Available
3621.205 g/mol
T3d2521
  • Amide
  • Amine
  • Animal Toxin
  • Natural Compound
  • Organic Compound
  • Protein
  • Scorpion Toxin
Maurotoxin acts by blocking several types of voltage-gated potassium channel. (L1059)
Number of Targets: 7
T3D2522Noxiustoxin
85205-49-8
Not Available
4201.920 g/mol
T3d2522
  • Amide
  • Amine
  • Animal Toxin
  • Natural Compound
  • Organic Compound
  • Protein
  • Scorpion Toxin
Noxiustoxin blocks voltage-gated non-inactivating potassium channels and unblocks inactivating potassium channels blocked by alpha-dendrotoxin in synaptosomes. It also...more
Number of Targets: 23
Displaying toxin 2026 - 2050 of 3678 in total