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Displaying toxin 2001 - 2025 of 3678 in total
T3DB ID Name
CAS Number
Formula
Weight
StructureTypeMechanism of Toxicity
T3D2468Prophalloin
67739-84-8
C35H48N8O9S
756.869 g/mol
Thumb
  • Amide
  • Amine
  • Ether
  • Fungal Toxin
  • Mycotoxin
  • Natural Compound
  • Organic Compound
  • Phallotoxin
Phallotoxins bind actin, preventing its depolymerization and poisoning the cell. They bind specifically at the interface between F-actin subunits, locking adjacent sub...more
Number of Targets: 6
T3D2469Phalloin
28227-92-1
C35H48N8O10S
772.868 g/mol
Thumb
  • Amide
  • Amine
  • Ether
  • Fungal Toxin
  • Mycotoxin
  • Natural Compound
  • Organic Compound
  • Phallotoxin
Phallotoxins bind actin, preventing its depolymerization and poisoning the cell. They bind specifically at the interface between F-actin subunits, locking adjacent sub...more
Number of Targets: 6
T3D2470Phallisin
19774-69-7
C35H48N8O12S
804.867 g/mol
Thumb
  • Amide
  • Amine
  • Ether
  • Fungal Toxin
  • Mycotoxin
  • Natural Compound
  • Organic Compound
  • Phallotoxin
Phallotoxins bind actin, preventing its depolymerization and poisoning the cell. They bind specifically at the interface between F-actin subunits, locking adjacent sub...more
Number of Targets: 6
T3D2471Phallacidin
26645-35-2
Not Available
2570.930 g/mol
T3d2471
  • Amide
  • Amine
  • Fungal Toxin
  • Mycotoxin
  • Natural Compound
  • Organic Compound
  • Phallotoxin
  • Protein
Phallotoxins bind actin, preventing its depolymerization and poisoning the cell. They bind specifically at the interface between F-actin subunits, locking adjacent sub...more
Number of Targets: 6
T3D2472Phallacin
53568-40-4
C37H50N8O12S
830.904 g/mol
Thumb
  • Amide
  • Amine
  • Ether
  • Fungal Toxin
  • Mycotoxin
  • Natural Compound
  • Organic Compound
  • Phallotoxin
Phallotoxins bind actin, preventing its depolymerization and poisoning the cell. They bind specifically at the interface between F-actin subunits, locking adjacent sub...more
Number of Targets: 6
T3D2473Phallisacin
58286-46-7
C37H50N8O14S
862.903 g/mol
Thumb
  • Amide
  • Amine
  • Ether
  • Fungal Toxin
  • Mycotoxin
  • Natural Compound
  • Organic Compound
  • Phallotoxin
Phallotoxins bind actin, preventing its depolymerization and poisoning the cell. They bind specifically at the interface between F-actin subunits, locking adjacent sub...more
Number of Targets: 6
T3D2474Naftidrofuryl
31329-57-4
C24H33NO3
383.524 g/mol
Thumb
  • Amine
  • Drug
  • Ester
  • Ether
  • Organic Compound
  • Synthetic Compound
Naftidrofuryl blocks the type 2 serotonin (5-HT2) receptors and thereby inhibits the effects of serotonin-induced vasoconstriction or platelet aggregation. It is also ...more
Number of Targets: 3
T3D2477Insulin
11061-68-0
Not Available
11980.795 g/mol
T3d2477
  • Amide
  • Amine
  • Animal Toxin
  • Antidiabetic Agent
  • Hormone
  • Natural Compound
  • Organic Compound
  • Protein
Insulin has a direct inhibitory effect on the lipase concerned with the mobilization of fattty acids. Insulin binds to a receptor on the surface of the target cell and...more
Number of Targets: 56
T3D2478Levofloxacin
100986-85-4
C18H20FN3O4
361.368 g/mol
Thumb
  • Amide
  • Amine
  • Anti-Bacterial Agent
  • Anti-Infective Agent, Urinary
  • Drug
  • Ester
  • Ether
  • Food Toxin
  • Metabolite
  • Nucleic Acid Synthesis Inhibitor
  • Organic Compound
  • Organofluoride
  • Quinolone
  • Synthetic Compound
Levofloxacin inhibits bacterial type II topoisomerases, topoisomerase IV and DNA gyrase. Levofloxacin, like other fluoroquinolones, inhibits the A subunits of DNA gyra...more
Number of Targets: 3
T3D2479Vindesine
53643-48-4
C43H55N5O7
753.926 g/mol
Thumb
  • Amide
  • Amine
  • Antineoplastic Agent
  • Antineoplastic Agent, Phytogenic
  • Drug
  • Ester
  • Ether
  • Metabolite
  • Organic Compound
  • Synthetic Compound
  • Tubulin Modulator
Vindesine acts by causing the arrest of cells in metaphase mitosis through its inhibition tubulin mitotic funcitoning. The drug is cell-cycle specific for the S phase.
Number of Targets: 1
T3D2480Amitriptyline
50-48-6
C20H23N
277.403 g/mol
Thumb
  • Adrenergic Uptake Inhibitor
  • Amine
  • Analgesic, Non-Narcotic
  • Antidepressive Agent, Tricyclic
  • Drug
  • Metabolite
  • Organic Compound
  • Synthetic Compound
Amitriptyline is metabolized to nortriptyline which inhibits the reuptake of norepinephrine and serotonin almost equally. Amitriptyline inhibits the membrane pump mech...more
Number of Targets: 44
T3D2481Ricin
9009-86-3
Not Available
64089.975 g/mol
T3d2481
  • Amide
  • Amine
  • Natural Compound
  • Organic Compound
  • Plant Toxin
  • Protein
Pure ricin consists of a neutral A chain and an acidic B chain connected by S--S bonds. The A chain is capable of inhibiting protein synthesis which results in its tox...more
Number of Targets: 1
T3D2482Dapsone
80-08-0
C12H12N2O2S
248.301 g/mol
Thumb
  • Amine
  • Anti-Infective Agent
  • Anti-Inflammatory Agent
  • Antimalarial
  • Antimycobacterial
  • Drug
  • Folic Acid Antagonist
  • Leprostatic Agent
  • Metabolite
  • Organic Compound
  • Synthetic Compound
Dapsone acts against bacteria and protozoa in the same way as sulphonamides, that is by inhibiting the synthesis of dihydrofolic acid through competition with para-ami...more
Number of Targets: 3
T3D2483Glipizide
29094-61-9
C21H27N5O4S
445.535 g/mol
Thumb
  • Amide
  • Amine
  • Drug
  • Hypoglycemic Agent
  • Metabolite
  • Organic Compound
  • Synthetic Compound
Sulfonylureas likely bind to ATP-sensitive potassium-channel receptors on the pancreatic cell surface, reducing potassium conductance and causing depolarization of the...more
Number of Targets: 3
T3D2484Tetrodotoxin
4368-28-9
C11H17N3O8
319.268 g/mol
Thumb
  • Amide
  • Amine
  • Animal Toxin
  • Ether
  • Marine Toxin
  • Natural Compound
  • Organic Compound
  • Sodium Channel Blocker
Tetrodotoxin binds to what is known as site 1 of the fast voltage-gated sodium channel. Site 1 is located at the extracellular pore opening of the ion channel. The bin...more
Number of Targets: 14
T3D2486Methotrexate
59-05-2
C20H22N8O5
454.439 g/mol
Thumb
  • Abortifacient Agent
  • Abortifacient Agent, Nonsteroidal
  • Amide
  • Amine
  • Antimetabolite
  • Antimetabolite, Antineoplastic
  • Antineoplastic Agent
  • Antirheumatic Agent
  • Dermatologic Agent
  • Drug
  • Enzyme Inhibitor
  • Ester
  • Folic Acid Antagonist
  • Immunosuppressive Agent
  • Metabolite
  • Nucleic Acid Synthesis Inhibitor
  • Organic Compound
  • Synthetic Compound
Methotrexate anti-tumor activity is a result of the inhibition of folic acid reductase, leading to inhibition of DNA synthesis and inhibition of cellular replication. ...more
Number of Targets: 11
T3D2487Apamin (Apis mellifera)
24345-16-2
Not Available
5223.305 g/mol
T3d2487
  • Amide
  • Amine
  • Animal Toxin
  • Insect Toxin
  • Natural Compound
  • Organic Compound
  • Protein
Apamin binds to the SK channels (small conductance Ca2+-activated K+ channels) in the brain and spinal cord and inhibits them, likely by acting as a pore blocker. Inhi...more
Number of Targets: 3
T3D2489Philanthotoxin
77108-00-0
C23H41N5O3
435.603 g/mol
Thumb
  • Amide
  • Amine
  • Animal Toxin
  • Insect Toxin
  • Natural Compound
  • Organic Compound
Philanthotoxins block glutamate receptors, especially the calcium permeable AMPA receptor and kainate receptor. (L1016)
Number of Targets: 9
T3D2490alpha-Pompilidotoxin
202075-91-0
Not Available
1530.850 g/mol
T3d2490
  • Amide
  • Amine
  • Animal Toxin
  • Insect Toxin
  • Natural Compound
  • Organic Compound
  • Protein
Pompilidotoxin slows down inactivation of neuronal, but not heart sodium channels, potentiating synaptic transmission. This is believed to be done by binding to the n...more
Number of Targets: 10
T3D2491beta-Pompilidotoxin
216064-36-7
Not Available
1558.860 g/mol
T3d2491
  • Amide
  • Amine
  • Animal Toxin
  • Insect Toxin
  • Natural Compound
  • Organic Compound
  • Protein
Pompilidotoxin slows down inactivation of neuronal, but not heart sodium channels, potentiating synaptic transmission. This is believed to be done by binding to the n...more
Number of Targets: 10
T3D2492Holocyclotoxin
88254-04-0
Not Available
7834.125 g/mol
T3d2492
  • Amide
  • Amine
  • Animal Toxin
  • Insect Toxin
  • Natural Compound
  • Organic Compound
  • Protein
Holocyclotoxin produces paralysis by acting at the neuromuscular junction. (A2834)
Number of Targets: 0
T3D2493Poneratoxin
137084-94-7
Not Available
2757.330 g/mol
T3d2493
  • Amide
  • Amine
  • Animal Toxin
  • Insect Toxin
  • Natural Compound
  • Organic Compound
  • Protein
Poneratoxin affects voltage-dependent sodium ion channels and is known to block nicotinic synaptic transmission in the insect central nervous system. (L1019)
Number of Targets: 14
T3D2494omega-Agatoxin
145017-83-0
Not Available
12807.575 g/mol
T3d2494
  • Amide
  • Amine
  • Animal Toxin
  • Natural Compound
  • Organic Compound
  • Protein
  • Spider Toxin
omega-Agatoxins block the calcium channels in the presynaptic terminals of the neuromuscular junction in insects and vertebrates. This reduces calcium influx, resultin...more
Number of Targets: 1
T3D2495Atracotoxin, omega- (Hadronyche versuta)
193981-10-1
Not Available
4055.410 g/mol
T3d2495
  • Amide
  • Amine
  • Animal Toxin
  • Natural Compound
  • Organic Compound
  • Protein
  • Spider Toxin
omega-Atracotoxins inhibit invertebrate voltage-gated calcium channel currents. (T170, L1812)
Number of Targets: 0
T3D2496Versutoxin
114264-83-4
Not Available
4855.645 g/mol
T3d2496
  • Amide
  • Amine
  • Animal Toxin
  • Natural Compound
  • Organic Compound
  • Protein
  • Spider Toxin
Versutoxin inhibits both insect and mammalian voltage-gated sodium channels. It binds to site 3 in tetrodotoxin-sensitive sodium channels, which slows their inactivati...more
Number of Targets: 14
Displaying toxin 2001 - 2025 of 3678 in total