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Displaying toxin 3026 - 3050 of 3678 in total
T3DB ID Name
CAS Number
Formula
Weight
StructureTypeMechanism of Toxicity
T3D4026(+)-Calycanthine
595-05-1
C22H26N4
346.469 g/mol
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  • Amine
  • Food Toxin
  • Metabolite
  • Natural Compound
  • Organic Compound
  • Plant Toxin
The principal alkaloid of the family Calycanthaceae, calycanthine has long been recognized as a central convulsant. Convulsant actions of calycanthine is mediated, at ...more
Number of Targets: 0
T3D4027(S)-Isocorydine
475-67-2
C20H23NO4
341.401 g/mol
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  • Amine
  • Ether
  • Food Toxin
  • Metabolite
  • Natural Compound
  • Organic Compound
  • Plant Toxin
Isocorydine induces G2/M phase arrest by increasing cyclin B1 and p-CDK1 expression levels, which was caused by decreasing the expression and inhibiting the activation...more
Number of Targets: 1
T3D4028(S)-2-Propylpiperidine
458-88-8
C8H17N
127.227 g/mol
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  • Amine
  • Food Toxin
  • Metabolite
  • Natural Compound
  • Organic Compound
  • Plant Toxin
(S)-2-Propylpiperidine is a neurotoxin which disrupts the peripheral nervous system. It is toxic to humans and all classes of livestock; less than 0.2g is fatal to hum...more
Number of Targets: 0
T3D4029Okadaic acid
78111-17-8
C44H68O13
805.003 g/mol
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  • Animal Toxin
  • Ether
  • Food Toxin
  • Ionophore
  • Marine Toxin
  • Metabolite
  • Natural Compound
  • Organic Compound
Okadaic acid (OA) dramatically increases both nerve growth factor (NGF) mRNA content (50-fold) and NGF secretion (100-fold) in astrocytes. Okadaic acid also activated ...more
Number of Targets: 1
T3D4030Dinophysistoxin 1
81720-10-7
C45H70O13
819.030 g/mol
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  • Animal Toxin
  • Ether
  • Food Toxin
  • Marine Toxin
  • Metabolite
  • Natural Compound
  • Organic Compound
Dinophysistoxin 1 (DTX1) is the analogue of okadaic acid causing diarrheic shellfish poisoning (DSP) in humans shortly after the ingestion of contaminated seafood. DTX...more
Number of Targets: 0
T3D4032Cyclochlorotine
12663-46-6
C24H31Cl2N5O7
572.438 g/mol
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  • Amide
  • Amine
  • Food Toxin
  • Fungal Toxin
  • Metabolite
  • Natural Compound
  • Organic Compound
  • Organochloride
Cyclochlorotine (CC) causes hepatic necrosis and has carcinogenic properties. The in vitro application of CC on myocytes induced disruption of myofibrils and large acc...more
Number of Targets: 0
T3D4038Gonyautoxin I
60748-39-2
C10H17N7O9S
411.348 g/mol
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  • Amide
  • Amine
  • Animal Toxin
  • Ester
  • Ether
  • Food Toxin
  • Marine Toxin
  • Metabolite
  • Natural Compound
  • Organic Compound
The gonyautoxin toxicity is caused by the reversibly binding to its receptor site on the voltage-gated sodium channel on excitable cells, thus blocking the influx of N...more
Number of Targets: 0
T3D4039Gonyautoxin II
60508-89-6
C10H17N7O8S
395.349 g/mol
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  • Amide
  • Amine
  • Animal Toxin
  • Ester
  • Ether
  • Food Toxin
  • Marine Toxin
  • Metabolite
  • Natural Compound
  • Organic Compound
The gonyautoxin toxicity is caused by the reversibly binding to its receptor site on the voltage-gated sodium channel on excitable cells, thus blocking the influx of N...more
Number of Targets: 0
T3D4040Domoic acid
14277-97-5
C15H21NO6
311.330 g/mol
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  • Amine
  • Animal Toxin
  • Food Toxin
  • Marine Toxin
  • Metabolite
  • Natural Compound
  • Organic Compound
Domoic acid acts as a neurotoxin. It induces excitotoxicity by an integrative action on ionotropic glutamate receptors at both sides of the synapse for which it has hi...more
Number of Targets: 1
T3D4042alpha-Solanine
20562-02-1
C45H73NO15
868.059 g/mol
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  • Amine
  • Food Toxin
  • Metabolite
  • Natural Compound
  • Organic Compound
  • Plant Toxin
Solanum glycoalkaloids can inhibit cholinesterase, disrupt cell membranes, and be teratogenic (cause birth defects). One study suggests that the toxic mechanism of sol...more
Number of Targets: 0
T3D4050alpha-Chaconine
20562-03-2
C45H73NO14
852.059 g/mol
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  • Amine
  • Food Toxin
  • Metabolite
  • Natural Compound
  • Organic Compound
  • Plant Toxin
Alpha-Chaconine has inhibitory effect on lung adenocarcinoma cell metastasis in vitro. Alpha-chaconine could inhibit phosphorylation of c-Jun N-terminal kinase (JNK) a...more
Number of Targets: 0
T3D4051Gymnodimine
173792-58-0
C32H45NO4
507.704 g/mol
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  • Animal Toxin
  • Ester
  • Ether
  • Food Toxin
  • Marine Toxin
  • Metabolite
  • Natural Compound
  • Organic Compound
Gymnodimine exerts its toxic effects via binding to nicotinic acetylcholine receptors with picomolar affinities with no sign of apparent reversibility in short time fr...more
Number of Targets: 0
T3D4052alpha-Zearalenol
36455-72-8
C18H24O5
320.380 g/mol
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  • Ester
  • Ether
  • Fungal Toxin
  • Metabolite
  • Natural Compound
  • Organic Compound
Mycotoxins, such as alpha-zearalenol (alpha-ZOL) and beta-zearalenol (beta-ZOL), as contaminants of animal food can impair fertility and can cause abnormal fetal devel...more
Number of Targets: 0
T3D4053beta-Zearalenol
71030-11-0
C18H24O5
320.380 g/mol
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  • Ester
  • Ether
  • Fungal Toxin
  • Metabolite
  • Natural Compound
  • Organic Compound
Mycotoxins, such as alpha-zearalenol (alpha-ZOL) and beta-zearalenol (beta-ZOL), as contaminants of animal food can impair fertility and can cause abnormal fetal devel...more
Number of Targets: 1
T3D4056Debromoaplysiatoxin
52423-28-6
C32H48O10
592.718 g/mol
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  • Animal Toxin
  • Bacterial Toxin
  • Ester
  • Ether
  • Marine Toxin
  • Natural Compound
  • Organic Compound
Debromoaplysiatoxin have the ability to evoke biological and biochemical responses in cells, and belong to the TPA (12-O-tetradecanoylphorbol 13-acetate) type tumor pr...more
Number of Targets: 0
T3D4059Senecionine
130-01-8
C18H25NO5
335.395 g/mol
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  • Amine
  • Ester
  • Ether
  • Natural Compound
  • Organic Compound
  • Plant Toxin
Senecionine is classified as a pyrrolizidine alkaloid (PA). Unsaturated pyrrolizidine alkaloids are hepatotoxic, that is, damaging to the liver. PAs also cause hepatic...more
Number of Targets: 0
T3D4060Retronecine
480-85-3
C8H13NO2
155.194 g/mol
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  • Amine
  • Natural Compound
  • Organic Compound
  • Plant Toxin
Retronecine is classified as a pyrrolizidine alkaloid (PA). Unsaturated pyrrolizidine alkaloids are hepatotoxic, that is, damaging to the liver. PAs also cause hepatic...more
Number of Targets: 0
T3D4061Veratridine
71-62-5
C36H51NO11
673.790 g/mol
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  • Amine
  • Ester
  • Ether
  • Natural Compound
  • Organic Compound
  • Plant Toxin
Veratridine is a steroid-derived alkaloid from plants in the Liliaceae family that functions as a neurotoxin by abolishing inactivation of sodium ion channels. It bind...more
Number of Targets: 0
T3D4063Ranunculin
644-69-9
C11H16O8
276.240 g/mol
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  • Ester
  • Natural Compound
  • Organic Compound
  • Plant Toxin
Ranunculin (RAN) inhibited the incorporation of 3H-labeled precursors into DNA and RNA of L1210 cells. RAN (15 mumol/L) markedly decreased DNA synthesis catalyzed by D...more
Number of Targets: 0
T3D4064Lycorine
476-28-8
C16H17NO4
287.311 g/mol
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  • Amine
  • Natural Compound
  • Organic Compound
  • Plant Toxin
Lycorine is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholinestera...more
Number of Targets: 1
T3D4065Mesaconitine
2752-64-9
C33H45NO11
631.711 g/mol
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  • Amine
  • Ester
  • Ether
  • Natural Compound
  • Organic Compound
  • Plant Toxin
Mesaconitine (MA) is one of the Aconitum sp. alkaloids. The primary toxicity of Aconitum sp. alkaloids is on the heart and the central nervous system. They can induce ...more
Number of Targets: 0
T3D4066Ryanodine
15662-33-6
C25H35NO9
493.547 g/mol
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  • Ester
  • Insecticide
  • Natural Compound
  • Organic Compound
  • Pesticide
  • Plant Toxin
Ryanodine has extremely high affinity to the open-form ryanodine receptor, a group of calcium channels found in skeletal muscle, smooth muscle, and heart muscle cells....more
Number of Targets: 1
T3D4067Convallatoxin
508-75-8
C29H42O10
550.638 g/mol
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  • Aldehyde
  • Ester
  • Food Toxin
  • Natural Compound
  • Organic Compound
  • Plant Toxin
Convallatoxin (CNT) is classified as a cardiac glycoside. Cardiac glycosides are well known Na+/K+-ATPase inhibitors, and some of them are used to treat congestive hea...more
Number of Targets: 0
T3D4068C-Curarine
7168-64-1
C40H44N4O
596.803 g/mol
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  • Amine
  • Ether
  • Natural Compound
  • Organic Compound
  • Plant Toxin
It has been prpoposed that surarine speeds up destruction of chemical transmitter, and raises the threshold point at which excess of the transmitter is able to exert i...more
Number of Targets: 0
T3D4069Phorbol
17673-25-5
C20H28O6
364.433 g/mol
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  • Ester
  • Industrial/Workplace Toxin
  • Natural Compound
  • Organic Compound
  • Plant Toxin
The term 'phorbol' is used to describe the family of naturally occurring compounds that can be referred to as tigliane diterpenes. Phorbol esters are the tetracyclic d...more
Number of Targets: 0
Displaying toxin 3026 - 3050 of 3678 in total