Browsing Toxins By Category
Displaying toxin 2451 - 2475 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D2934 | Maprotiline 10262-69-8 | C20H23N 277.403 g/mol |  |
| Maprotiline exerts its antidepressant action by inhibition of presynaptic uptake of catecholamines, thereby increasing their concentration at the synaptic clefts of th...more Number of Targets: 17 |
| T3D2520 | Margatoxin 145808-47-5 | Not Available 4184.990 g/mol |  |
| Margatoxin blocks potassium channels, resulting in a loss of outward current and affecting neurotransmitter release. (L1057) Number of Targets: 1 |
| T3D2536 | Marinobufagenin 470-42-8 | C24H32O5 400.508 g/mol |  |
| Marinobufagin blocks the sodium/potassium pump in heart tissue. (L1084, L1085) Number of Targets: 0 |
| T3D4813 | Masoprocol 500-38-9 | C18H22O4 302.365 g/mol |  |
| Although the exact mechanism of action is not known, studies have shown that masoprocol is a potent 5-lipoxygenase inhibitor and has antiproliferative activity against...more Number of Targets: 9 |
| T3D2580 | Mastoparan (Vespa tropica) 72093-21-1 | Not Available 1625.055 g/mol |  |
| Mastoparan causes varying types of exocytosis, depending on its location. In mast cells it causes histamine secretion, while in platelets and chromaffin cells the rele...more Number of Targets: 0 |
| T3D4081 | Matrine 519-02-8 | C15H24N2O 248.364 g/mol |  |
| The nervous system is the main target organ by the toxicity of matrine. Morphological observation revealed degenerative changes of the nerve cells in the brain tissue ...more Number of Targets: 0 |
| T3D2582 | Maurocalcin 269745-22-4 | Not Available 3864.570 g/mol |  |
| Maurocalcin potently and reversibly modifies channel gating behaviour of the type 1 ryanodine receptor by inducing prominent subconductance behaviour. (T170) Number of Targets: 1 |
| T3D2521 | Maurotoxin 188240-41-7 | Not Available 3621.205 g/mol |  |
| Maurotoxin acts by blocking several types of voltage-gated potassium channel. (L1059) Number of Targets: 7 |
| T3D2830 | Mazindol 22232-71-9 | C16H13ClN2O 284.740 g/mol |  |
| Although the mechanism of action of the sympathomimetics in the treatment of obesity is not fully known, these medications have pharmacological effects similar to thos...more Number of Targets: 4 |
| T3D0980 | Mecarbinzid 27386-64-7 | C13H16N4O3S 308.356 g/mol |  |
| Mecarbinzid targets beta tubulin in actively dividing cells. It binds to microtubules, interfering with cell functions, such as meiosis and intracellular transportatio...more Number of Targets: 1 |
| T3D4204 | Mechlorethamine 51-75-2 | C5H11Cl2N 156.054 g/mol |  |
| Alkylating agents work by three different mechanisms: 1) attachment of alkyl groups to DNA bases, resulting in the DNA being fragmented by repair enzymes in their atte...more Number of Targets: 1 |
| T3D2874 | Meclizine 569-65-3 | C25H27ClN2 390.948 g/mol |  |
| Along with its actions as an antagonist at H1-receptors, meclizine also possesses anticholinergic, central nervous system depressant, and local anesthetic effects. Mec...more Number of Targets: 2 |
| T3D4648 | Medazepam 2898-12-6 | C16H15ClN2 270.757 g/mol |  |
| Benzodiazepines bind nonspecifically to benzodiazepine receptors BNZ1, which mediates sleep, and BNZ2, which affects affects muscle relaxation, anticonvulsant activity...more Number of Targets: 19 |
| T3D4730 | Medroxyprogesterone Acetate 71-58-9 | C24H34O4 386.524 g/mol |  |
| Progestins diffuse freely into target cells in the female reproductive tract, mammary gland, hypothalamus, and the pituitary and bind to the progesterone receptor. Onc...more Number of Targets: 2 |
| T3D3520 | Melamine 108-78-1 | C3H6N6 126.120 g/mol |  |
| Melamine causes carcinomas of the urinary bladder at high doses (in male rats). Formation of bladder stones occurred and these calculi are necessary for the induction ...more Number of Targets: 1 |
| T3D2972 | Melatonin 73-31-4 | C13H16N2O2 232.278 g/mol |  |
| Melatonin is a derivative of tryptophan. It binds to melatonin receptor type 1A, which then acts on adenylate cylcase and the inhibition of a cAMP signal transduction ...more Number of Targets: 18 |
| T3D2624 | Melittin (Apis mellifera) 20449-79-0 | Not Available 7584.775 g/mol |  |
| Melittin has strong haemolytic activity. It integrates into cell membranes and has multiple effects, probably, as a result of its interaction with negatively charged p...more Number of Targets: 12 |
| T3D2899 | Meloxicam 71125-38-7 | C14H13N3O4S2 351.401 g/mol |  |
| Anti-inflammatory effects of meloxicam are believed to be due to inhibition of prostaglandin synthetase (cylooxygenase), leading to the inhibition of prostaglandin syn...more Number of Targets: 2 |
| T3D4702 | Melphalan 148-82-3 | C13H18Cl2N2O2 305.200 g/mol |  |
| Alkylating agents work by three different mechanisms: 1) attachment of alkyl groups to DNA bases (primarily at the N-7 position of guanine and to a lesser extent, at t...more Number of Targets: 1 |
| T3D2967 | Memantine 19982-08-2 | C12H21N 179.302 g/mol |  |
| Memantine exerts its action through uncompetitive NMDA receptor antagonism, binding preferentially to the NMDA receptor-operated cation channels. Prolonged increased l...more Number of Targets: 8 |
| T3D2704 | Menadione 58-27-5 | C11H8O2 172.180 g/mol |  |
| Menadione (vitamin K3) is involved as a cofactor in the posttranslational gamma-carboxylation of glutamic acid residues of certain proteins in the body. These proteins...more Number of Targets: 24 |
| T3D3224 | Menthol 2216-51-5 | C10H20O 156.265 g/mol |  |
| Menthol acts as a weak Kappa Opioid Receptor Agonist. Number of Targets: 4 |
| T3D2795 | Meperidine 57-42-1 | C15H21NO2 247.333 g/mol |  |
| Meperidine is primarily a kappa-opiate receptor agonist and also has local anesthetic effects. Meperidine has more affinity for the kappa-receptor than morphine. Opiat...more Number of Targets: 15 |
| T3D3874 | Mepiquat chloride 24307-26-4 | C7H16ClN 149.662 g/mol |  |
| Not Available Number of Targets: 2 |
| T3D2942 | Mepivacaine 96-88-8 | C15H22N2O 246.348 g/mol |  |
| Local anesthetics block the generation and the conduction of nerve impulses, presumably by increasing the threshold for electrical excitation in the nerve, by slowing ...more Number of Targets: 1 |