Browsing Toxins By Category
Displaying toxin 2201 - 2225 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D0975 | Hyquincarb 56716-21-3 | C13H18N2O2 234.294 g/mol |  |
| Hyquincarb is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoylation of the active sites...more Number of Targets: 2 |
| T3D2667 | Ibandronate 114084-78-5 | C9H23NO7P2 319.229 g/mol |  |
| The action of ibandronate on bone tissue is based partly on its affinity for hydroxyapatite, which is part of the mineral matrix of bone. Nitrogen-containing bisphosph...more Number of Targets: 3 |
| T3D2512 | Iberiotoxin 129203-60-7 | Not Available 4253.920 g/mol |  |
| Iberiotoxin binds to the outer face of the large-conductance calcium-activated potassium channels with high affinity. It selectively inhibits the current by decreasin...more Number of Targets: 5 |
| T3D2455 | Ibotenic acid 2552-55-8 | C5H6N2O4 158.112 g/mol |  |
| A portion of ibotenic acid is metabolized to muscimol, a potent GABAA agonist, activating the receptor for the brain's major inhibitory neurotransmitter, GABA. Muscimo...more Number of Targets: 12 |
| T3D2970 | Ibuprofen 15687-27-1 | C13H18O2 206.281 g/mol |  |
| The exact mechanism of action of ibuprofen is unknown. Ibuprofen is a non-selective inhibitor of cyclooxygenase, an enzyme invovled in prostaglandin synthesis via the ...more Number of Targets: 15 |
| T3D3859 | Icaridin 119515-38-7 | C12H23NO3 229.316 g/mol |  |
| Not Available Number of Targets: 7 |
| T3D3513 | Ifosfamide 3778-73-2 | C7H15Cl2N2O2P 261.086 g/mol |  |
| After metabolic activation, active metabolites of ifosfamide alkylate or bind with many intracellular molecular structures, including nucleic acids. The cytotoxic acti...more Number of Targets: 3 |
| T3D4825 | Ilepatril 473289-62-2 | C22H28N2O5S 432.533 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D3861 | Imazamox 114311-32-9 | C15H19N3O4 305.329 g/mol |  |
| Not Available Number of Targets: 3 |
| T3D3862 | Imazapic 104098-48-8 | C14H17N3O3 275.303 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D4516 | Imazapyr 81334-34-1 | C13H15N3O3 261.277 g/mol |  |
| Not Available Number of Targets: 5 |
| T3D3863 | Imazaquin 81335-37-7 | C17H17N3O3 311.335 g/mol |  |
| Not Available Number of Targets: 6 |
| T3D0797 | Imidacloprid 105827-78-9 | C9H10ClN5O2 255.661 g/mol |  |
| Imidacloprid acts on the nicotinic acetylcholine receptor; the chlorination inhibits degradation by acetylcholine-esterase (L1130). Number of Targets: 12 |
| T3D3625 | Imidazolidinyl urea 39236-46-9 | C11H16N8O8 388.294 g/mol |  |
| Imidazolidinyl urea is a formaldehyde releaser. It is likely that formaldehyde toxicity occurs when intracellular levels saturate formaldehyde dehydrogenase activity, ...more Number of Targets: 2 |
| T3D4739 | Imipenem 74431-23-5 | C12H17N3O4S 299.346 g/mol |  |
| Imipenem acts as an antimicrobial through the inhibition of cell wall synthesis of various gram-positive and gram-negative bacteria. This inhibition of cell wall synth...more Number of Targets: 0 |
| T3D2797 | Imipramine 50-49-7 | C19H24N2 280.407 g/mol |  |
| Imipramine works by inhibiting the neuronal reuptake of the neurotransmitters norepinephrine and serotonin. It binds the sodium-dependent serotonin transporter and sod...more Number of Targets: 34 |
| T3D0838 | Imperatorin 482-44-0 | C16H14O4 270.280 g/mol |  |
| Imperatorin is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholinest...more Number of Targets: 5 |
| T3D2514 | Imperatoxin-1 Not Available | Not Available 18663.670 g/mol |  |
| Imperatoxin-I is an inhibitor which decreases the influx of Ca2+ from the sarcoplasmatic reticulum into the cell. Imperatoxin-I acts on the Ryanodine receptors (RyR), ...more Number of Targets: 3 |
| T3D2513 | Imperatoxin-A 172451-37-5 | Not Available 3764.370 g/mol |  |
| Imperatoxin-A is an activator which enhances the influx of Ca2+ from the sarcoplasmatic reticulum into the cell. Imperatoxin-A acts on the Ryanodine receptors (RyR), w...more Number of Targets: 3 |
| T3D4819 | Indene 95-13-6 | C9H8 116.160 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D0174 | Indeno(1,2,3-cd)pyrene 193-39-5 | C22H12 276.331 g/mol |  |
| The ability of PAH's to bind to blood proteins such as albumin allows them to be transported throughout the body. Many PAH's induce the expression of cytochrome P450 e...more Number of Targets: 3 |
| T3D4157 | Indican 1336-79-4 | C8H6KNO4S 251.301 g/mol |  |
| Uremic toxins such as indican are actively transported into the kidneys via organic ion transporters (especially OAT3). Increased levels of uremic toxins can stimulate...more Number of Targets: 3 |
| T3D1291 | Indium arsenide 1303-11-3 | AsIn 189.740 g/mol |  |
| Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co...more Number of Targets: 44 |
| T3D2411 | Indium phosphide 22398-80-7 | InP 145.792 g/mol |  |
| Phosphine inhibits cytochrome c oxidase, preventing mitochondrial oxidative phosphorylation. This non-competitive inhibition prevents cellular respiration and leads to...more Number of Targets: 20 |
| T3D1733 | Indium(I) bromide 14280-53-6 | BrIn 194.722 g/mol |  |
| Bromine is a powerful oxidizing agent and is able to release oxygen free radicals from the water in mucous membranes. These free radicals are also potent oxidizers and...more Number of Targets: 6 |