Browsing Toxins By Category
Displaying toxin 2051 - 2075 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D0971 | Formetanate hydrochloride 23422-53-9 | C11H16ClN3O2 257.717 g/mol |  |
| Formetanate hydrochloride is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoylation of t...more Number of Targets: 4 |
| T3D0972 | Formparanate 17702-57-7 | C12H18ClN3O2 271.743 g/mol |  |
| Formparanate is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoylation of the active sit...more Number of Targets: 2 |
| T3D4827 | Forskolin 64657-11-0 and 66575-29-9 | C22H34O7 410.501 g/mol |  |
| Not Available Number of Targets: 17 |
| T3D0973 | Fosamine 59682-52-9 | C3H8NO4P 153.074 g/mol |  |
| Fosamine is an eye irritant. It likely binds to or modifies the TRPA1 protein which leads to a lachrymatory (tearing) response.
Number of Targets: 1 |
| T3D3036 | Fosphenytoin 93390-81-9 | C16H15N2O6P 362.274 g/mol |  |
| Fosphenytoin is a prodrug of phenytoin and accordingly, its anticonvulsant effects are attributable to phenytoin. Phenytoin acts on sodium channels on the neuronal cel...more Number of Targets: 1 |
| T3D3855 | Fosthiazate 98886-44-3 | C9H18NO3PS2 283.348 g/mol |  |
| Fosthiazate is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholinest...more Number of Targets: 10 |
| T3D2954 | Frovatriptan 158747-02-5 | C14H17N3O 243.304 g/mol |  |
| Three distinct pharmacological actions have been implicated in the antimigraine effect of the triptans: (1) stimulation of presynaptic 5-HT1D receptors, which serves t...more Number of Targets: 2 |
| T3D4757 | Fulvestrant 129453-61-8 | C32H47F5O3S 606.771 g/mol |  |
| Fulvestrant competitively and reversibly binds to estrogen receptors present in cancer cells and achieves its anti-estrogen effects through two separate mechanisms. Fi...more Number of Targets: 7 |
| T3D3760 | Fumagillin 23110-15-8 | C26H34O7 458.544 g/mol |  |
| Fumagillin blocks blood vessel formation (angiogenesis) by inhibiting the enzyme methionine aminopeptidase 2. This prevents angiogenesis by arresting endothelial cells...more Number of Targets: 1 |
| T3D4237 | Fumaric acid 110-17-8 | C4H4O4 116.072 g/mol |  |
| Acute Toxicity: Fumarate is also an endogenous electrophile and reacts spontaneously with cysteine residues in proteins by a Michael addition reaction to form S-(2-suc...more Number of Targets: 17 |
| T3D3103 | Fumarin 117-52-2 | C17H14O5 298.290 g/mol |  |
| Fumarin inhibits the enzyme Vitamin K epoxide reductase. This enzyme is needed for the reconstitution of the vitamin K in its cycle from vitamin K-epoxide, and so fuma...more Number of Targets: 1 |
| T3D3742 | Fumitremorgin A 12626-18-5 | C32H41N3O7 579.684 g/mol |  |
| Tremorgenic mycotoxins exert their toxic effects by interfering with neurotransmitter release, possibly by causing degeneration of nerve terminals. They are thought to...more Number of Targets: 22 |
| T3D3743 | Fumitremorgin B 12626-17-4 | C27H33N3O5 479.568 g/mol |  |
| Tremorgenic mycotoxins exert their toxic effects by interfering with neurotransmitter release, possibly by causing degeneration of nerve terminals. They are thought to...more Number of Targets: 23 |
| T3D3744 | Fumitremorgin C 118974-02-0 | C22H25N3O3 379.452 g/mol |  |
| Fumitremorgin C inhibits ATP-binding cassette transporter (ACBG2), also known as breast cancer resistance protein. ACBG2 is known to confer multidrug resistance and al...more Number of Targets: 23 |
| T3D3603 | Fumonisin B1 116355-83-0 | C34H59NO15 721.830 g/mol |  |
| Fumonisins are similar in structure to the long-chain base backbones of sphingolipids, allowing it to inhibit of the biosynthesis of sphingosine and more complex sphin...more Number of Targets: 16 |
| T3D3697 | Fumonisin B2 116355-84-1 | C34H59NO14 705.831 g/mol |  |
| Fumonisins are similar in structure to the long-chain base backbones of sphingolipids, allowing it to inhibit of the biosynthesis of sphingosine and more complex sphin...more Number of Targets: 1 |
| T3D4203 | Furan 110-00-9 | C4H4O 68.074 g/mol |  |
| Furan is a potent hepatotoxin and hepatocarcinogen in rodents, causing hepatocellular adenomas and carcinomas in rats and mice, and high incidences of cholangiocarcino...more Number of Targets: 3 |
| T3D0974 | Furathiocarb 65907-30-4 | C18H26N2O5S 382.474 g/mol |  |
| Furathiocarb is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoylation of the active sit...more Number of Targets: 2 |
| T3D3707 | Fusarenon-X 23255-69-8 | C17H22O8 354.352 g/mol |  |
| Unlike many other mycotoxins, trichothecenes do not require metabolic activation to exert their biological activity, instead directly reacting with cellular components...more Number of Targets: 2 |
| T3D3741 | Fusaric Acid 536-69-6 | C10H13NO2 179.216 g/mol |  |
| Fusaric acid affects neurotransmitter levels by acting as a partial inhibitor on tyrosine-hydroxylase and an inhibitor on dopamine-beta-hydroxylase. This has been show...more Number of Targets: 3 |
| T3D2952 | Gabapentin 60142-96-3 | C9H17NO2 171.237 g/mol |  |
| Gabapentin interacts with cortical neurons at auxillary subunits of voltage-sensitive calcium channels. Gabapentin increases the synaptic concentration of GABA, enhanc...more Number of Targets: 7 |
| T3D3560 | Gadolinium nitrate 10168-81-7 | GdN3O9 343.260 g/mol |  |
| Nitrate's toxicity is a result of it's conversion to nitrite once in the body. Nitrite causes the autocatalytic oxidation of oxyhemoglobin to hydrogen peroxide and met...more Number of Targets: 9 |
| T3D4349 | Galactitol 608-66-2 | C6H14O6 182.172 g/mol |  |
| Accumulation of galactitol in the body has been shown to be toxic. Accumulation of galactitol in the lens causes the osmotic phenomena and results in cataract formatio...more Number of Targets: 0 |
| T3D4960 | Galactonic acid 13382-27-9 | C6H12O7 196.155 g/mol |  |
| Not Available Number of Targets: 0 |
| T3D4962 | Galactosylsphingosine 2238-90-6 | C24H47NO7 461.633 g/mol |  |
| Not Available Number of Targets: 0 |