Browsing Toxins By Category
Displaying toxin 2026 - 2050 of 3678 in total
T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
---|---|---|---|---|---|
T3D1649 | Fluorescein isothiocyanate 27072-45-3 | C21H11NO5S 389.381 g/mol |
| Cyanide is an inhibitor of cytochrome c oxidase in the fourth complex of the electron transport chain (found in the membrane of the mitochondria of eukaryotic cells). ...more Number of Targets: 39 | |
T3D0211 | Fluorine 7782-41-4 | F 18.999 g/mol |
| Fluoride ions are incorporated into bone by substituting for hydroxyl groups in the carbonate-apatite structure to produce hydroxyfluorapatite, thus altering the miner...more Number of Targets: 7 | |
T3D2578 | Fluoroacetamide 640-19-7 | C2H4FNO 77.058 g/mol |
| Fluoroacetate produces its toxin action by inhibiting the citric acid cycle. The fluorine substituted acetate becomes incorporated, as a normal acetate, into fluoroace...more Number of Targets: 0 | |
T3D3504 | Fluoroacetic acid 144-49-0 | C2H3FO2 78.042 g/mol |
| Fluoroacetate is similar to acetate, which has a pivotal role in cellular metabolism. Fluoroacetate disrupts the citric acid cycle by combining with coenzyme A to form...more Number of Targets: 2 | |
T3D4776 | Fluorouracil 51-21-8 | C4H3FN2O2 130.077 g/mol |
| The precise mechanism of action has not been fully determined, but the main mechanism of fluorouracil is thought to be the binding of the deoxyribonucleotide of the dr...more Number of Targets: 5 | |
T3D4512 | Fluoxastrobin 361377-29-9 | C21H16ClFN4O5 458.827 g/mol |
| Not Available Number of Targets: 25 | |
T3D2802 | Fluoxetine 54910-89-3 | C17H18F3NO 309.326 g/mol |
| Fluoxetine is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholineste...more Number of Targets: 18 | |
T3D3010 | Fluoxymesterone 76-43-7 | C20H29FO3 336.441 g/mol |
| Fluoxymesterone is a synthetic androgenic anabolic steroid and is approximately 5 times as potent as natural methyltestosterone. Like testosterone and other androgenic...more Number of Targets: 5 | |
T3D2920 | Flupenthixol 2709-56-0 | C23H27F3N2OS 436.533 g/mol |
| Flupenthixol is a thioxanthene antipsychotic. The mechanism of action of Flupenthixol is not completely understood. Flupenthixol is a powerful antagonist of both D1 an...more Number of Targets: 8 | |
T3D2840 | Fluphenazine 69-23-8 | C22H26F3N3OS 437.522 g/mol |
| Fluphenazine blocks postsynaptic mesolimbic dopaminergic D1 and D2 receptors in the brain; depresses the release of hypothalamic and hypophyseal hormones and is believ...more Number of Targets: 17 | |
T3D2860 | Flurazepam 17617-23-1 | C21H23ClFN3O 387.878 g/mol |
| Benzodiazepines bind nonspecifically to bezodiazepine receptors BNZ1, which mediates sleep, and BNZ2, which affects affects muscle relaxation, anticonvulsant activity,...more Number of Targets: 21 | |
T3D2866 | Flurbiprofen 5104-49-4 | C15H13FO2 244.261 g/mol |
| Similar to other NSAIAs, the anti-inflammatory effect of flurbiprofen occurs via reversible inhibition of cyclooxygenase (COX), the enzyme responsible for the conversi...more Number of Targets: 11 | |
T3D3848 | Fluroxypyr 69377-81-7 | C7H5Cl2FN2O3 255.031 g/mol |
| Not Available Number of Targets: 7 | |
T3D3849 | Fluroxypyr-meptyl 81406-37-3 | C15H21Cl2FN2O3 367.243 g/mol |
| Not Available Number of Targets: 10 | |
T3D3850 | Flusilazole 85509-19-9 | C16H15F2N3Si 315.393 g/mol |
| Flusilazole has a dose-related inhibition of serum testosterone and estradiol concentrations in rats. This inhibition of testosterone and estradiol biosynthesis may di...more Number of Targets: 20 | |
T3D4768 | Flutamide 13311-84-7 | C11H11F3N2O3 276.212 g/mol |
| Flutamide is a nonsteroidal antiandrogen that blocks the action of both endogenous and exogenous testosterone by binding to the androgen receptor. In addition Flutamid...more Number of Targets: 7 | |
T3D3851 | Fluthiacet-methyl 117337-19-6 | C15H15ClFN3O3S2 403.879 g/mol |
| Not Available Number of Targets: 10 | |
T3D3852 | Flutolanil 66332-96-5 | C17H16F3NO2 323.310 g/mol |
| Not Available Number of Targets: 11 | |
T3D1039 | Fluvalinate 69409-94-5 | C26H22ClF3N2O3 502.913 g/mol |
| Both type I and type II pyrethroids exert their effect by prolonging the open phase of the sodium channel gates when a nerve cell is excited. They appear to bind to th...more Number of Targets: 19 | |
T3D2705 | Fluvoxamine 54739-18-3 | C15H21F3N2O2 318.335 g/mol |
| The exact mechanism of action of fluvoxamine has not been fully determined, but appears to be linked to its inhibition of CNS neuronal uptake of serotonin. Fluvoxamine...more Number of Targets: 8 | |
T3D2698 | Folic acid 59-30-3 | C19H19N7O6 441.398 g/mol |
| Folic acid, as it is biochemically inactive, is converted to tetrahydrofolic acid and methyltetrahydrofolate by dihydrofolate reductase. These folic acid congeners are...more Number of Targets: 8 | |
T3D3853 | Folpet 133-07-3 | C9H4Cl3NO2S 296.558 g/mol |
| Not Available Number of Targets: 8 | |
T3D4513 | Forchlorfenuron 68157-60-8 | C12H10ClN3O 247.680 g/mol |
| Not Available Number of Targets: 18 | |
T3D0244 | Formaldehyde 50-00-0 | CH2O 30.026 g/mol |
| It is likely that formaldehyde toxicity occurs when intracellular levels saturate formaldehyde dehydrogenase activity, allowing the unmetabolized intact molecule to ex...more Number of Targets: 3 | |
T3D0970 | Formetanate 22259-30-9 | C11H15N3O2 221.256 g/mol |
| Formetanate is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoylation of the active site...more Number of Targets: 2 |