Browsing Toxins By Category
Displaying toxin 976 - 1000 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D3791 | Ametryn 834-12-8 | C9H17N5S 227.330 g/mol |  |
| Not Available Number of Targets: 12 |
| T3D1086 | Amidochlor 40164-67-8 | C15H21ClN2O2 296.792 g/mol |  |
| Binds to nAChRs in nervous systems. It also causes endocrine disruption in humans by binding to and inhibiting the estrogen receptor. (T10, A590) Number of Targets: 12 |
| T3D4259 | Aminoadipic acid 542-32-5 | C6H11NO4 161.156 g/mol |  |
| Not Available Number of Targets: 4 |
| T3D0922 | Aminocarb 2032-59-9 | C11H16N2O2 208.257 g/mol |  |
| Aminocarb is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoylation of the active sites ...more Number of Targets: 2 |
| T3D4806 | Aminoglutethimide 125-84-8 | C13H16N2O2 232.278 g/mol |  |
| Aminoglutethimide reduces the production of D5-pregnenolone and blocks several other steps in steroid synthesis, including the C-11, C-18, and C-21 hydroxylations and ...more Number of Targets: 2 |
| T3D4741 | Aminopterin 54-62-6 | C19H20N8O5 440.413 g/mol |  |
| Aminopterin is an amino derivative of folic acid which binds competitively to the dihydrofolate reductase enzyme to block tetrahydrofolate synthesis. Tetrahydrofolate ...more Number of Targets: 2 |
| T3D4737 | Amiodarone 1951-25-3 | C25H29I2NO3 645.312 g/mol |  |
| The antiarrhythmic effect of amiodarone may be due to at least two major actions. It prolongs the myocardial cell-action potential (phase 3) duration and refractory pe...more Number of Targets: 4 |
| T3D3792 | Amitraz 33089-61-1 | C19H23N3 293.406 g/mol |  |
| The pharmacological activity of amitraz includes different mechanisms of action leading to toxic effects in humans as well as in animals. Many of these effects and mos...more Number of Targets: 8 |
| T3D2480 | Amitriptyline 50-48-6 | C20H23N 277.403 g/mol |  |
| Amitriptyline is metabolized to nortriptyline which inhibits the reuptake of norepinephrine and serotonin almost equally. Amitriptyline inhibits the membrane pump mech...more Number of Targets: 44 |
| T3D0157 | Ammonia 7664-41-7 | H3N 17.031 g/mol |  |
| The topical damage caused by ammonia is probably due mainly to its alkaline properties. Its high water solubility allows it to dissolve in moisture on the mucous membr...more Number of Targets: 2 |
| T3D0285 | Ammonium arsenate 7784-44-3 | AsH9N2O4 176.004 g/mol |  |
| Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co...more Number of Targets: 44 |
| T3D1721 | Ammonium bromide 12124-97-9 | BrH4N 97.942 g/mol |  |
| Bromine is a powerful oxidizing agent and is able to release oxygen free radicals from the water in mucous membranes. These free radicals are also potent oxidizers and...more Number of Targets: 6 |
| T3D0714 | Ammonium chromate 7788-98-9 | CrH8N2O4 152.071 g/mol |  |
| Hexavalent chromium's carcinogenic effects are caused by its metabolites, pentavalent and trivalent chromium. The DNA damage may be caused by hydroxyl radicals produce...more Number of Targets: 5 |
| T3D0700 | Ammonium dichromate 7789-09-5 | Cr2H8N2O7 252.065 g/mol |  |
| Hexavalent chromium's carcinogenic effects are caused by its metabolites, pentavalent and trivalent chromium. The DNA damage may be caused by hydroxyl radicals produce...more Number of Targets: 5 |
| T3D1160 | Ammonium diuranate 7783-22-4 | H10N2O5U 356.119 g/mol |  |
| Uranium is combined with either bicarbonate or a plasma protein in the blood but once in the kidney, it is released and forms complexes with phosphate ligands and prot...more Number of Targets: 1 |
| T3D1581 | Ammonium hexachloro-palladate(IV) 7440-05-3 | Cl6H8N2Pd 355.210 g/mol |  |
| Due to their ability to form strong complexes with both inorganic and organic ligands, palladium ions can disturb cellular equilibria, replace other essential ions, an...more Number of Targets: 6 |
| T3D3619 | Ammonium laureth sulfate 32612-48-9 | C14H33NO5S 327.481 g/mol |  |
| While ammonium laureth sulfate itself is not toxic, it is a nitrosating agent. Nitrosating agents may decompose and/or react to cause nitrosamine contamination. Nitros...more Number of Targets: 1 |
| T3D3620 | Ammonium lauryl sulfate 2235-54-3 | C12H29NO4S 283.428 g/mol |  |
| While ammonium lauryl sulfate itself is not toxic, it is a nitrosating agent. Nitrosating agents may decompose and/or react to cause nitrosamine contamination. Nitrosa...more Number of Targets: 2 |
| T3D1645 | Ammonium metavanadate 7803-55-6 | H4NO3V 116.978 g/mol |  |
| Vanadium damages alveolar macrophages by decreasing the macrophage membrane integrity, thus impairing the cells' phagocytotic ability and viability. The pentavalent fo...more Number of Targets: 47 |
| T3D3552 | Ammonium nitrate 6484-52-2 | H4N2O3 80.043 g/mol |  |
| Nitrate's toxicity is a result of it's conversion to nitrite once in the body. Nitrite causes the autocatalytic oxidation of oxyhemoglobin to hydrogen peroxide and met...more Number of Targets: 9 |
| T3D3548 | Ammonium nitrite 13446-48-5 | H4N2O2 64.044 g/mol |  |
| Nitrite causes the autocatalytic oxidation of oxyhemoglobin to hydrogen peroxide and methemoglobin. This elevation of methemoglobin levels is a condition known as meth...more Number of Targets: 9 |
| T3D1914 | Ammonium perchlorate 7790-98-9 | ClH4NO4 117.489 g/mol |  |
| The primary and most sensitive target of the perchlorate anion (perchlorate) is the thyroid gland. Perchlorate inhibits the transport of iodide (I-) from the blood int...more Number of Targets: 2 |
| T3D1153 | Ammonium permanganate 13446-10-1 | H4MnNO4 136.974 g/mol |  |
| Manganese is a cellular toxicant that can impair transport systems, enzyme activities, and receptor functions. It primarily targets the central nervous system, particu...more Number of Targets: 5 |
| T3D1582 | Ammonium tetrachloro-palladate(II) 19168-23-1 | Cl4H8N2Pd 284.310 g/mol |  |
| Due to their ability to form strong complexes with both inorganic and organic ligands, palladium ions can disturb cellular equilibria, replace other essential ions, an...more Number of Targets: 6 |
| T3D1452 | Ammonium tetrathiocyanato-diamminechromate(III) 13573-16-5 | C4H10CrN7S4 336.425 g/mol |  |
| Trivalent chromium may also form complexes with peptides, proteins, and DNA, resulting in DNA-protein crosslinks, DNA strand breaks, DNA-DNA interstrand crosslinks, ch...more Number of Targets: 44 |