Browsing Toxins By Category
Displaying toxin 2826 - 2850 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D3733 | Penitrem B 11076-67-8 | C37H45NO5 583.757 g/mol |  |
| Tremorgenic mycotoxins exert their toxic effects by interfering with neurotransmitter release, possibly by causing degeneration of nerve terminals. They are thought to...more Number of Targets: 27 |
| T3D3734 | Penitrem C 37318-84-6 | C37H44ClNO4 602.203 g/mol |  |
| Tremorgenic mycotoxins exert their toxic effects by interfering with neurotransmitter release, possibly by causing degeneration of nerve terminals. They are thought to...more Number of Targets: 27 |
| T3D3898 | Penoxsulam 219714-96-2 | C16H14F5N5O5S 483.370 g/mol |  |
| Not Available Number of Targets: 7 |
| T3D2040 | Pentabromodiphenyl ethers 32534-81-9 | C12H5Br5O 564.688 g/mol |  |
| Like other halogenated aromatic hydrocarbons, polybrominated diphenyl ethers bind to the cellular aryl hydrocarbon receptor (AhR), which regulates the synthesis of a v...more Number of Targets: 7 |
| T3D0629 | Pentacene 135-48-8 | C22H14 278.347 g/mol |  |
| The ability of PAH's to bind to blood proteins such as albumin allows them to be transported throughout the body. Many PAH's induce the expression of cytochrome P450 e...more Number of Targets: 3 |
| T3D0045 | Pentachlorophenol 87-86-5 | C6HCl5O 266.337 g/mol |  |
| Pentachlorophenol is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcho...more Number of Targets: 63 |
| T3D4782 | Pentadecane 629-62-9 | C15H32 212.415 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D0265 | Pentaerythritol tetranitrate 1978-11-05 | C5H8N4O12 316.137 g/mol |  |
| Nitrate's toxicity is a result of it's conversion to nitrite once in the body. Nitrite causes the autocatalytic oxidation of oxyhemoglobin to hydrogen peroxide and met...more Number of Targets: 10 |
| T3D3526 | Pentamidine 100-33-4 | C19H24N4O2 340.420 g/mol |  |
| The mode of action of pentamidine is not fully understood. It is thought that the drug interferes with nuclear metabolism producing inhibition of the synthesis of DNA,...more Number of Targets: 11 |
| T3D3428 | Pentane 109-66-0 | C5H12 72.149 g/mol |  |
| Pentane is a central nervous system depressant. It affects the peripheral nervous system through demyelinization and axonal degeneration. (T29) Number of Targets: 0 |
| T3D2850 | Pentazocine 359-83-1 | C19H27NO 285.424 g/mol |  |
| The preponderance of evidence suggests that pentazocine antagonizes the opioid effects by competing for the same receptor sites, especially the opioid mu receptor. Number of Targets: 4 |
| T3D2745 | Pentobarbital 76-74-4 | C11H18N2O3 226.272 g/mol |  |
| Pentobarbital binds at a distinct binding site associated with a Cl- ionopore at the GABAA receptor, increasing the duration of time for which the Cl- ionopore is open...more Number of Targets: 16 |
| T3D4177 | Pentosidine 124505-87-9 | C17H26N6O4 378.426 g/mol |  |
| Uremic toxins such as pentosidine are actively transported into the kidneys via organic ion transporters (especially OAT3). Increased levels of uremic toxins can stimu...more Number of Targets: 3 |
| T3D2822 | Pentostatin 53910-25-1 | C11H16N4O4 268.269 g/mol |  |
| Pentostatin is a potent transition state inhibitor of adenosine deaminase (ADA), the greatest activity of which is found in cells of the lymphoid system. T-cells have ...more Number of Targets: 1 |
| T3D3999 | Perfluorodecanoic acid 335-76-2 | C10HF19O2 514.083 g/mol |  |
| Not Available Number of Targets: 5 |
| T3D4001 | Perfluorononanoic acid 375-95-1 | C9HF17O2 464.076 g/mol |  |
| Not Available Number of Targets: 8 |
| T3D3899 | Perfluorooctanesulfonic acid 1763-23-1 | C8HF17O3S 500.130 g/mol |  |
| Not Available Number of Targets: 19 |
| T3D3985 | Perfluorooctanoic acid 335-67-1 | C8HF15O2 414.068 g/mol |  |
| Not Available Number of Targets: 11 |
| T3D4005 | Perfluoroundecanoic acid 2058-94-8 | C11HF21O2 564.091 g/mol |  |
| Not Available Number of Targets: 9 |
| T3D2601 | Perfringolysin O 71329-60-7 | Not Available 55829.405 g/mol |  |
| Perfringolysin O binds to cholesterol on eukaryotic cell membranes, then forms oligomeric pores. This causes membrane damage and lysis of the cell. (A2832) Number of Targets: 1 |
| T3D3011 | Pergolide 66104-22-1 | C19H26N2S 314.488 g/mol |  |
| The dopamine D2 receptor is a 7-transmembrane G-protein coupled receptor associated with Gi proteins. In lactotrophs, stimulation of dopamine D2 receptor causes inhibi...more Number of Targets: 17 |
| T3D2975 | Perhexiline 6621-47-2 | C19H35N 277.488 g/mol |  |
| Perhexiline binds to the mitochondrial enzyme carnitine palmitoyltransferase (CPT)-1 and CPT-2. It acts by shifting myocardial substrate utilisation from long chain fa...more Number of Targets: 4 |
| T3D1850 | Permethrin 52645-53-1 | C21H20Cl2O3 391.288 g/mol |  |
| Pyrethroids exert their effect by prolonging the open phase of the sodium channel gates when a nerve cell is excited. They appear to bind to the membrane lipid phase i...more Number of Targets: 26 |
| T3D2913 | Perphenazine 58-39-9 | C21H26ClN3OS 403.969 g/mol |  |
| Binds to the dopamine D1 and dopamine D2 receptors and inhibits their activity. The mechanism of the anti-emetic effect is due predominantly to blockage of the dopamin...more Number of Targets: 13 |
| T3D2595 | Pertussis toxin 70323-44-3 | Not Available 29973.970 g/mol |  |
| After binding to the cell receptors, pertussis toxin (PTX) is endocytosed and the A moiety translocates into the cytosol where it expresses the ADP-ribosyltransferase ...more Number of Targets: 6 |