Search Results for compounds

Matched symptoms: … Symptoms of low dose exposure include excessive salivation and eye-watering. Acute dose symptoms ... include severe nausea/vomiting, salivation, sweating, bradycardia, hypotension, collapse, and ... convulsions. Increasing muscle weakness is a possibility and may result in death if respiratory muscles are …
Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched treatment: … effects of excess acetylcholine and reactivate AChE. Atropine can be used as an antidote in ... . Atropine is a muscarinic antagonist, and thus blocks the action of acetylcholine peripherally. ... bicarbonate. For skin contact, the skin should be washed with soap and water. If the compound has entered …
Matched description: … potent as the nerve agent sarin, and so is now rarely used as an insecticide due to the risk of ... Paraoxon is an acetylcholinesterase inhibitor. It is an organophosphate oxon, and the active ... metabolite of the insecticide parathion. It is also used as an opthamological drug against glaucoma …
Matched synonyms: … O,O-Diethyl-O-p-nitrophenylphosphoric acid …

Matched symptoms: … Symptoms of asbestos exposure include shortness of breath, often accompanied by a cough. (L222) …
Matched treatment: … the levels of reactive oxygen species, such as free radical scavengers (ascorbic acid, bemitil ... medications that open up the bronchial tubes and allow the passage of air. In more severe asbestosis ... In vitro studies have shown that the effects of asbestos can be diminished by compounds that reduce …
Matched description: … amphibole family of minerals and has needlelike fibres. Crocidolite asbestos can be found in a ... variety of construction materials and insulation materials. Abestos is toxic and inhalation of asbestos ... . While all forms of asbestos are hazardous and can cause cancer, amphibole forms of asbestos are …

Matched symptoms: … . Sudden bronchospasm, swelling of oral and laryngeal mucous membranes, and anaphylactoid reactions have ... activation can occur. Nausea, vomiting and abdominal pain commonly occur and develop following ingestion ... , dyspnea, wheezing, chest pain, irritability to sound and touch, and bronchospasm may occur too …
Matched carcinogenicity: … 3, not classifiable as to its carcinogenicity to humans. (L135) …
Matched treatment: … bronchospasm with inhaled beta2 agonist and oral or parenteral corticosteroids. In case of eye exposure ... Following oral exposure, the treatment is symptomatic and supportive and includes monitoring for ... the development of hypersensitivity reactions with respiratory distress. Provide adequate airway …
Matched description: … Agricultural, public health and animal husbandry insecticide.Fenvalerate is an insecticide. It is a ... mixture of four optical isomers which have different insecticidal activities. The 2-S alpha (or SS ... ) configuration is the most insecticidally active isomer. Fenvalerate consists of about 23% of this …
Matched synonyms: … Fenvaleric acid …

Matched symptoms: … the body and can cause nausea, vomiting, loss of appetite, and weight loss. It can also cause ... . Shortness of breath from fluid buildup in the space between the lungs and the chest wall (pleural effusion) can also be present. ... As a uremic toxin, this compound can cause uremic syndrome. Uremic syndrome may affect any part of …
Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched treatment: … Kidney dialysis is usually needed to relieve the symptoms of uremic syndrome until normal kidney function can be restored. …
Matched description: … lead to a number of conditions including renal damage, chronic kidney disease and cardiovascular ... -links between the arginine and lysine residues in collagen. It is formed in a reaction of the amino ... levels of precursors of carbonyl compounds, and for this reason is considered a reliable surrogate …
Matched synonyms: … (2S)-2-amino-6-(2-{[(4S)-4-amino-4-carboxybutyl]amino}-4H-imidazo[4,5-b]pyridin-4-yl)hexanoic acid …

Matched symptoms: … Symptions of chronic lead poisoning include reduced cognitive abilities, nausea, abdominal pain ... , headache and, in extreme cases, seizures, comas, and death. There are also associated gastrointestinal …
Matched carcinogenicity: … Organic lead compounds are not classifiable as to their carcinogenicity to humans (Group 3). To the …
Matched description: … Basic lead carbonate is a chemical compound of lead that occurs naturally as the mineral ... hydrocerussite. It was once used in cosmetics and lead paint, but has since been banned in most areas due to ... its toxicity. Lead is a heavy metal and stable element with the symbol Pb and the atomic number 82 …
Matched synonyms: … Basic lead carbonic acid …

Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched description: … position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3. ... The L-triiodothyronine (T₃, liothyronine) thyroid hormone is normally synthesized and ... >, levothyroxine, L-thyroxine). Most T3 is derived from peripheral monodeiodination of T4 at the 5 …

Matched symptoms: … The symptoms of an overdose of ethyl loflazepate include sleepiness, agitation and ataxia ... . Hypotonia may also occur in severe cases. These symptoms occur much more frequently and severely in children ... .[12] Death from therapeutic maintenance doses of ethyl loflazepate taken for 2 – 3 weeks has been …
Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched treatment: … a general rule, medical observation and supportive care are the mainstay of treatment of ... with activated charcoal is not beneficial in pure benzodiazepine overdose as the risk of adverse ... General supportive measures should be employed, along with intravenous fluids, and an adequate …
Matched description: … Ethyl loflazepate (marketed under the brand names Meilax, Ronlax and Victan) is a drug which is a ... benzodiazepine derivative. It possesses anxiolytic, anticonvulsant, sedative and skeletal muscle ... relaxant properties. In animal studies it was found to have low toxicity, although in rats evidence of …
Matched synonyms: … Ethyl loflazepic acid …

Matched symptoms: … the body and can cause nausea, vomiting, loss of appetite, and weight loss. It can also cause ... . Shortness of breath from fluid buildup in the space between the lungs and the chest wall (pleural effusion) can also be present. ... As a uremic toxin, this compound can cause uremic syndrome. Uremic syndrome may affect any part of …
Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched treatment: … Kidney dialysis is usually needed to relieve the symptoms of uremic syndrome until normal kidney function can be restored. …
Matched description: … toxins can lead to a number of conditions including renal damage, chronic kidney disease and ... based upon their chemical and physical characteristics: 1) small, water-soluble, non-protein-bound ... compounds, such as urea; 2) small, lipid-soluble and/or protein-bound compounds, such as the phenols and …

Matched symptoms: … periphery pulse, loss of peripheral sensation, edema and ultimately the death and loss of affected tissues. (L1920, L1933) ... Convulsive ergotism can cause painful seizures and spasms, diarrhea, paresthesias, itching ... , headaches, nausea and vomiting. Usually the gastrointestinal effects precede the central nervous system …
Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched treatment: … Treatment for ergotism consists of vasodilators, anticoagulants and low molecular weight dextrans ... . Temporary sedation (e.g. haloperidol) will be necessary in hallucination and diazepam is used for convulsions. There is no specific antidote. (L1921, L1933) …
Matched description: … correlates with the relief of migraine headache and 2) activation of 5-HT_1D receptors on sensory ... -dihydro derivative of ergotamine. It is used as a vasoconstrictor, specifically for the therapy of ... migraine disorders. Two theories have been proposed to explain the efficacy of 5-HT_1D

Matched symptoms: … , and hallucinations. Severe intoxications may produce coma, seizures, respiratory depression, and hypotension …
Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched treatment: … The prognosis in cases of severe poisoning is critically dependent upon prompt elimination of the ... drug, which may be achieved by inducing vomiting, irrigating the stomach, and by taking appropriate …
Matched description: … An anticonvulsant used to control grand mal and psychomotor or focal seizures. Its mode of action ... is not fully understood, but some of its actions resemble those of phenytoin; although there is …

Matched symptoms: … ). Overdosage of sulfonylureas including glipizide can produce hypoglycemia. …
Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched description: … conductance and causing depolarization of the membrane. Depolarization stimulates calcium ion influx ... hypoglycemic agent which is rapidly absorbed and completely metabolized. [PubChem]Sulfonylureas likely bind to ... through voltage-sensitive calcium channels, raising intracellular concentrations of calcium ions, which induces the secretion, or exocytosis, of insulin. …

Matched symptoms: … contact dermatitis, which is characterized by irritation and rashes. Ingesting large amounts of cobalt may cause nausea and vomiting. (L2090) …
Matched treatment: … Treatment of cobalt poisoning is symptomatic. (L29) …
Matched description: … Cobalt(II) formate is a chemical compound of cobalt. Cobalt is a metallic element with the atomic ... number 27. It is found naturally in rocks, soil, water, plants, and animals. In small amounts cobalt ... is an essential element for life, as it is part of vitamin B12. However, excess exposure is known to exhibit toxic effects. (L29, L30) …
Matched synonyms: … Cobalt(II) formic acid ... Formic acid cobalt(2+) salt ... Formic acid, cobalt(2+) salt …

Matched symptoms: … inhibition of nervous tissue acetylcholinesterase is reversible, and carbamates are more rapidly ... higher levels of exposure. Contraction of the pupils with blurred vision, incoordination, muscle twitching and slurred speech have been reported. (L795) ... As with organophosphates, the signs and symptoms are based on excessive cholinergic stimulation …
Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched treatment: … effects of excess acetylcholine and reactivate AChE. Atropine can be used as an antidote in ... . Atropine is a muscarinic antagonist, and thus blocks the action of acetylcholine peripherally. ... bicarbonate. For skin contact, the skin should be washed with soap and water. If the compound has entered …
Matched description: … Carbamate pesticides are derived from carbamic acid and kill insects in a similar fashion as ... , carbaryl, was introduced in 1956 and more of it has been used throughout the world than all other ... carbamates combined. Because of carbaryl's relatively low mammalian oral and dermal toxicity and …
Matched synonyms: … Carbamic acid, sulfanilyl-, methyl ester, monosodium salt …

Matched symptoms: … Acute exposure leads to irritation and burning at the site of exposure. (L958) Symptoms include ... cough, chest pain (severe), chest tightness, difficulty breathing and wheezing, tearing and burning of ... , weak pulse, collapse and shock. Chronic exposure: Symptoms of hyperammonia include: lethargy …
Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched treatment: … not induce vomiting. Rinse mouth with water (never give anything by mouth to an unconscious person ... cold running water for at least 15 minutes, followed by thorough washing with soap and water. If ... necessary, the person should shower and change contaminated clothing and shoes, and then must seek …
Matched description: … levels of ammonia have also been associated with diseases of the lower airways and interstitial lung ... mitochondrial function and oxidative stress, factors implicated in the induction of the mitochondrial ... in nearly all tissues and organs of the vertebrate organism; it is the most common endogenous …
Matched synonyms: … Spirit of hartshorn …

Matched symptoms: … Symptoms of low dose exposure include excessive salivation and eye-watering. Acute dose symptoms ... include severe nausea/vomiting, salivation, sweating, bradycardia, hypotension, collapse, and ... convulsions. Increasing muscle weakness is a possibility and may result in death if respiratory muscles are …
Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched treatment: … effects of excess acetylcholine and reactivate AChE. Atropine can be used as an antidote in ... . Atropine is a muscarinic antagonist, and thus blocks the action of acetylcholine peripherally. ... bicarbonate. For skin contact, the skin should be washed with soap and water. If the compound has entered …
Matched description: … Diaxozon is a toxic metabolic product of the insecticide Diazinon. Diazinon is a nonsystemic ... , and fleas in residential, non-food buildings. Diazinon was heavily used during the 1970s and early ... 1980s for general-purpose gardening use and indoor pest control. A bait form was used to control …
Matched synonyms: … Phosphoric acid, diethyl 6-methyl-2-(1-methylethyl)-4-pyrimidinyl ester …

Matched symptoms: … , hostility, and temporary paralysis. Respiratory depression was seen in a number of patients, including children, in the context of seizures. ... included: seizures including status epilepticus in patients with and without underlying seizure …
Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched treatment: … signs and observation of clinical status of the patient. Since tiagabine is mostly metabolized by the ... There is no specific antidote for overdose with Tiagabine. If indicated, elimination of unabsorbed ... maintain the airway. General supportive care of the patient is indicated including monitoring of vital …

Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched treatment: … overdose. Forced diuresis, alkalinization of urine, hemodialysis, or hemoperfusion may not be useful due to high protein binding. (L1712) ... Patients should be managed with symptomatic and supportive care following an NSAID overdose. In ... cases of acute overdose, gastric lavage followed by activated charcoal is recommended. Gastric lavage …
Matched description: … Meloxicam is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve the symptoms of ... arthritis, primary dysmenorrhea, fever; and as an analgesic, especially where there is an inflammatory ... , Melox, and Recoxa. In North America it is generally marketed under the brand name Mobic. In Latin America, the drug is marketed as Tenaron. [Wikipedia] …

Matched symptoms: … Symptions of chronic lead poisoning include reduced cognitive abilities, nausea, abdominal pain ... , headache and, in extreme cases, seizures, comas, and death. There are also associated gastrointestinal …
Matched carcinogenicity: … Organic lead compounds are not classifiable as to their carcinogenicity to humans (Group 3). To the …
Matched description: … Diethyldimethyl lead is an organolead compound. Lead is a heavy metal and stable element with the ... symbol Pb and the atomic number 82, existing in metallic, organic, and inorganic forms. It is mainly …

Matched symptoms: … Symptoms of overdose include confusion, drowsiness, blurred vision, tachycardia, nausea, diaphoresis, flushing, headache, and dry mouth. …
Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched description: … Omeprazole is a highly effective inhibitor of gastric acid secretion used in the therapy of stomach ... ulcers, dyspepsia, peptic ulcer disease , gastroesophageal reflux disease and Zollinger-Ellison ... syndrome. The drug inhibits the H(+)-K(+)-ATPase (H(+)-K(+)-exchanging ATPase) in the proton pump of …

Matched symptoms: … May cause skin, eye and respiratory tract irritation. May affect behavior/central nervous system ... and possible coma). If ingested, 2-bromopropane may cause gastrointestinal tract irritation with ... nausea, and vomiting. It may also affect behavior/central nervous system with symptoms similar to those …
Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched treatment: … EYES: irrigate opened eyes for several minutes under running water. INGESTION: do not induce ... cold running water for at least 15 minutes, followed by thorough washing with soap and water. If ... necessary, the person should shower and change contaminated clothing and shoes, and then must seek …
Matched description: … cleaning solvents such as chlorofluorocarbons. 2-Bromopropane is prepared by heating isopropanol with hydrobromic acid. …

Matched symptoms: … that are suggestive of repetitive discharges in neurons. These repetitive tremors and seizures can be initiated by tactile and auditory stimuli. (T10) ... Acute signs of DDT poisoning include paresthesia after oral ingestion. Studies have shown that a ... mammal poisoned with DDT-type agents displays periodic persistent tremoring and/or convulsive seizures …
Matched carcinogenicity: … Not directly listed by IARC, but carcinogenicity studies of this DDT metabolite are discussed in connection with DDT (L2151). …
Matched treatment: … Treatment of DDT exposure should be primarily directed towards decontamination and supportive care ... , as there is no specific antidote. The use of gastric lavage and activated charcoal for large ingestions may be effective. (L140) …
Matched description: … DDE, P,P'- is an isomer of dichlorodiphenyldichloroethylene, an organochlorine insecticide. It is ... one of the components of commercial mixtures of DDT. DDT was once a widely used pesticide, but today ... its agricultural use has been banned worldwide due to its toxicity and tendency to bioaccumulate …

Matched symptoms: … inhibition of nervous tissue acetylcholinesterase is reversible, and carbamates are more rapidly ... higher levels of exposure. Contraction of the pupils with blurred vision, incoordination, muscle twitching and slurred speech have been reported. (L795) ... As with organophosphates, the signs and symptoms are based on excessive cholinergic stimulation …
Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched treatment: … effects of excess acetylcholine and reactivate AChE. Atropine can be used as an antidote in ... . Atropine is a muscarinic antagonist, and thus blocks the action of acetylcholine peripherally. ... bicarbonate. For skin contact, the skin should be washed with soap and water. If the compound has entered …
Matched description: … Karbutilate is a carbamate pesticide. Carbamate pesticides are derived from carbamic acid and kill ... and agriculture. The first carbamate, carbaryl, was introduced in 1956 and more of it has been used ... settings. Most of the carbamates are extremely toxic to Hymenoptera, and precautions must be taken to …
Matched synonyms: … Karbutilic acid …

Matched symptoms: … Nitrate and nitrite poisoning causes methemoglobinemia. Symptoms include cyanosis, cardiac ... dysrhythmias and circulatory failure, and progressive central nervous system (CNS) effects. CNS effects can ... range from mild dizziness and lethargy to coma and convulsions. (L1137) …
Matched treatment: … Methemoglobinemia can be treated with supplemental oxygen and methylene blue 1% solution …
Matched description: … Potassium nitrate is a nitrate of potassium. It is used as an oxidizing component of gunpowder, a ... preservative, a fertilizer, and can also be found in some toothpastes. Nitrite is a toxic compound known to cause methemoglobinemia. (L1137, L1634) …
Matched synonyms: … Nitrate of potash ... Nitric acid potassium salt ... Nitric acid potassium salt (1:1) …

Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched description: … mammalian cells, this enhanced degradation is dependent on the presence of both a sterol and a non ... biosynthesis, induction of apoptosis, inhibition of cell cycle progression and actin cytoskeletal ... disorganization. Farnesol cellular availability is an important determinant of vascular tone in animals and …

Matched symptoms: … Short-term oral exposure to high concentrations of selenium may cause nausea, vomiting, and ... to either of these air-borne forms can cause respiratory irritation, bronchial spasms, and coughing ... arygria, a blue-gray discoloration of the skin and other body tissues. Argyria is a permanent effect but …
Matched carcinogenicity: … 3, not classifiable as to its carcinogenicity to humans. (L135) …
Matched treatment: … EYES: irrigate opened eyes for several minutes under running water. INGESTION: do not induce ... water for at least 15 minutes, followed by thorough washing with soap and water. If necessary, the ... person should shower and change contaminated clothing and shoes, and then must seek medical attention …
Matched description: … Silver(I) selenide is a chemical compound of silver and selenium. It is rarely found in the nature ... as mineral naumannite and is used in photography to produce selenium toning. Selenium is a nonmetal ... element with the atomic number 34 and the chemical symbol Se. Selenium rarely occurs in its …