Browsing Toxins
Displaying toxin 3651 - 3675 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D4977 | Edetic Acid 62-33-9 | C10H16N2O8 292.243 g/mol |  |
| The pharmacologic effects of edetate calcium disodium are due to the formation of chelates with divalent and trivalent metals. A stable chelate will form with any meta...more Number of Targets: 3 |
| T3D4978 | Cytarabine 147-94-4 | C9H13N3O5 243.217 g/mol |  |
| Cytarabine acts through direct DNA damage and incorporation into DNA. Cytarabine is cytotoxic to a wide variety of proliferating mammalian cells in culture. It exhibit...more Number of Targets: 3 |
| T3D4979 | Isoprenaline 7683-59-2 | C11H17NO3 211.258 g/mol |  |
| The pharmacologic effects of isoproterenol are at least in part attributable to stimulation through beta-adrenergic receptors of intracellular adenyl cyclase, the enzy...more Number of Targets: 7 |
| T3D4980 | Atorvastatin 134523-00-5 | C33H34FN2O5 557.632 g/mol |  |
| Atorvastatin selectively and competitively inhibits the hepatic enzyme HMG-CoA reductase. As HMG-CoA reductase is responsible for converting HMG-CoA to mevalonate in t...more Number of Targets: 3 |
| T3D4981 | Pioglitazone 111025-46-8 | C19H20N2O3S 356.439 g/mol |  |
| Pioglitazone acts as an agonist at peroxisome proliferator activated receptors (PPAR) in target tissues for insulin action such as adipose tissue, skeletal muscle, and...more Number of Targets: 3 |
| T3D4982 | Dexamethasone 50-02-2 | C22H29FO5 392.461 g/mol |  |
| Dexamethasone is a glucocorticoid agonist. Unbound dexamethasone crosses cell membranes and binds with high affinity to specific cytoplasmic glucocorticoid receptors. ...more Number of Targets: 7 |
| T3D4983 | Tiratricol 51-24-1 | C14H9I3O4 621.932 g/mol |  |
| Tiratricol is a naturally occurring metabolite of T4 (thyroxine) and a structural analog of T3 (triiodothyronine). Low concentrations of tiratricol are found in plasma...more Number of Targets: 1 |
| T3D4984 | Aniline 62-53-3 | C6H7N 93.127 g/mol |  |
| Aniline induces lipid peroxidation and protein oxidation in the spleen and that oxidative stress plays a role in the splenic toxicity of aniline. The hematopoietic sys...more Number of Targets: 2 |
| T3D4985 | Cinnamaldehyde 104-55-2 | C9H8O 132.159 g/mol |  |
| Cinnamaldehyde is an allergen. The physiologic effect of cinnamaldehyde is by means of increased histamine release and cell-mediated immunity. Number of Targets: 2 |
| T3D4986 | p-Anisidine 104-94-9 | C7H9NO 123.153 g/mol |  |
| p-Anisidine reacts with secondary oxidation products such as aldehydes and ketones in fats and oils. (Wikipedia) Number of Targets: 0 |
| T3D4987 | Dihydro-5-propyl-2(3H)-furanone 57129-71-2 | C7H12O2 128.169 g/mol |  |
| Not Available Number of Targets: 0 |
| T3D4988 | 9-(2-Carboxyphenyl)-3,6-bis(diethylamino)xanthylium(1+) 14899-08-2 | C28H31N2O3 443.557 g/mol |  |
| Not Available Number of Targets: 0 |
| T3D4989 | 3-Acetyl-4-hydroxy-6-methyl-2H-pyran-2-one 771-03-9 | C8H8O4 168.147 g/mol |  |
| Not Available Number of Targets: 0 |
| T3D4990 | 2,2,4-Trimethyl-1,3-pentadienol diisobutyrate 6846-50-0 | C16H30O4 286.407 g/mol |  |
| Not Available Number of Targets: 0 |
| T3D4991 | 9-Hydroxyphenanthrene 484-17-3 | C14H10O 194.229 g/mol |  |
| 9-phenanthrol is a recently identified inhibitor of the transient receptor potential melastatin (TRPM) 4 channel, a Ca(2+) -activated non-selective cation channel whos...more Number of Targets: 0 |
| T3D4992 | m-Dichlorobenzene 541-73-1 | C6H4Cl2 147.002 g/mol |  |
| The liver damage caused in rats by 1,3-dichlorobenzene is accompanied by induction of xenobiotic metabolizing enzymes of the phenobarbital type. In rats, a disturbance...more Number of Targets: 0 |
| T3D4993 | 2-hydroxyflutamide 52806-53-8 | C11H11F3N2O4 292.211 g/mol |  |
| Hydroxyflutamide is an antiandrogen. Antiandrogens alter the androgen pathway by blocking the appropriate receptors, competing for binding sites on the cell's surface,...more Number of Targets: 0 |
| T3D4994 | Dibenzylideneacetone 538-58-9 | C17H14O 234.293 g/mol |  |
| Not Available Number of Targets: 0 |
| T3D4995 | 22,23-dihydroavermectin b1a 71827-03-7 | C48H74O14 875.093 g/mol |  |
| Ivermectin binds selectively and with high affinity to glutamate-gated chloride ion channels in invertebrate muscle and nerve cells of the microfilaria. This binding c...more Number of Targets: 14 |
| T3D4996 | 22,23-dihydroavermectin b1b 70209-81-3 | C47H72O14 861.066 g/mol |  |
| Ivermectin binds selectively and with high affinity to glutamate-gated chloride ion channels in invertebrate muscle and nerve cells of the microfilaria. This binding c...more Number of Targets: 14 |
| T3D4997 | Carbon-14 14762-75-5 | CH4 18.035 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D4998 | Sulfur-35 15117-53-0 | H2S 36.985 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D4999 | Succinyl acetoacetate 65115-74-4 | C8H10O6 202.161 g/mol |  |
| Not Available Number of Targets: 0 |
| T3D5000 | Sulfuric acid 7664-93-9 | H2O4S 98.078 g/mol |  |
| Many strong acids cause tissue burns through the denaturation of proteins and partial hydrolysis of proteins. Most proteins denature at pH values of less than 3-4. T...more Number of Targets: 0 |
| T3D5001 | Succinic acid semialdehyde 692-29-5 | C4H6O3 102.089 g/mol |  | Not Available | Not Available Number of Targets: 0 |