Displaying toxin 2626 - 2650 of 3678 in total
T3DB ID Name
CAS Number
Formula
Weight
StructureTypeMechanism of Toxicity
T3D3580Sodium fluoroacetate
62-74-8
C2H2FNaO2
100.024 g/mol
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  • Organic Compound
  • Organofluoride
  • Pesticide
  • Synthetic Compound
Fluoroacetate is similar to acetate, which has a pivotal role in cellular metabolism. Fluoroacetate disrupts the citric acid cycle by combining with coenzyme A to form...more
Number of Targets: 0
T3D3582Lysergic Acid Diethylamide
50-37-3
C20H25N3O
323.432 g/mol
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  • Amide
  • Amine
  • Drug
  • Hallucinogen
  • Hypnotic and Sedative
  • Organic Compound
  • Serotonin Antagonist
  • Serotonin Receptor Agonist
  • Synthetic Compound
LSD preferentially inhibits serotonergic cell firing by acting as an agonist at the 5-HT1A receptors in the raphe nuclei, locus coeruleus, and cortex. It also acts as ...more
Number of Targets: 17
T3D3583Botulinum toxin
93384-43-1
Not Available
149452.615 g/mol
T3d3583
  • Amide
  • Amine
  • Anti-Wrinkle Agent
  • Antidystonic Agent
  • Bacterial Toxin
  • Natural Compound
  • Neuromuscular Blocking Agent
  • Organic Compound
  • Protein
  • Shigella Toxin
Botulinum toxin is a two-chain polypeptide with a 100-kDa heavy chain joined by a disulfide bond to a 50-kDa light chain. Following the attachment of the toxin heavy c...more
Number of Targets: 2
T3D3584Botulinum neurotoxin type G
Not Available
Not Available
149033.235 g/mol
T3d3584
  • Amide
  • Amine
  • Bacterial Toxin
  • Natural Compound
  • Organic Compound
  • Protein
  • Shigella Toxin
Botulinum toxin is a two-chain polypeptide with a 100-kDa heavy chain joined by a disulfide bond to a 50-kDa light chain. Following the attachment of the toxin heavy c...more
Number of Targets: 0
T3D3585beta-Amanitin
21150-22-1
Not Available
3445.915 g/mol
T3d3585
  • Amide
  • Amine
  • Fungal Toxin
  • Mycotoxin
  • Natural Compound
  • Organic Compound
  • Protein
The major toxic mechanism of amatoxins is the inhibition of RNA polymerase II, a vital enzyme in the synthesis of messenger RNA (mRNA), microRNA, and small nuclear RNA...more
Number of Targets: 14
T3D3586gamma-Amanitin
21150-23-2
Not Available
3706.230 g/mol
T3d3586
  • Amide
  • Amine
  • Fungal Toxin
  • Mycotoxin
  • Natural Compound
  • Organic Compound
  • Protein
The major toxic mechanism of amatoxins is the inhibition of RNA polymerase II, a vital enzyme in the synthesis of messenger RNA (mRNA), microRNA, and small nuclear RNA...more
Number of Targets: 14
T3D3587epsilon-Amanitin
21705-02-2
C39H53N9O14S
903.955 g/mol
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  • Amide
  • Amine
  • Fungal Toxin
  • Mycotoxin
  • Natural Compound
  • Organic Compound
The major toxic mechanism of amatoxins is the inhibition of RNA polymerase II, a vital enzyme in the synthesis of messenger RNA (mRNA), microRNA, and small nuclear RNA...more
Number of Targets: 14
T3D3588Amanullin
21803-57-6
C39H54N10O12S
886.971 g/mol
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  • Amide
  • Amine
  • Fungal Toxin
  • Mycotoxin
  • Natural Compound
  • Organic Compound
The major toxic mechanism of amatoxins is the inhibition of RNA polymerase II, a vital enzyme in the synthesis of messenger RNA (mRNA), microRNA, and small nuclear RNA...more
Number of Targets: 14
T3D3589Amanullinic acid
54532-45-5
C39H53N9O13S
887.956 g/mol
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  • Amide
  • Amine
  • Fungal Toxin
  • Mycotoxin
  • Natural Compound
  • Organic Compound
The major toxic mechanism of amatoxins is the inhibition of RNA polymerase II, a vital enzyme in the synthesis of messenger RNA (mRNA), microRNA, and small nuclear RNA...more
Number of Targets: 14
T3D3590Amaninamide
58311-65-2
C39H54N10O13S
902.970 g/mol
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  • Amide
  • Amine
  • Fungal Toxin
  • Mycotoxin
  • Natural Compound
  • Organic Compound
The major toxic mechanism of amatoxins is the inhibition of RNA polymerase II, a vital enzyme in the synthesis of messenger RNA (mRNA), microRNA, and small nuclear RNA...more
Number of Targets: 14
T3D3591Amanin
21150-21-0
C39H53N9O14S
903.955 g/mol
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  • Amide
  • Amine
  • Fungal Toxin
  • Mycotoxin
  • Natural Compound
  • Organic Compound
The major toxic mechanism of amatoxins is the inhibition of RNA polymerase II, a vital enzyme in the synthesis of messenger RNA (mRNA), microRNA, and small nuclear RNA...more
Number of Targets: 14
T3D3592Proamanullin
54532-46-6
C39H54N10O11S
870.971 g/mol
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  • Amide
  • Amine
  • Fungal Toxin
  • Mycotoxin
  • Natural Compound
  • Organic Compound
The major toxic mechanism of amatoxins is the inhibition of RNA polymerase II, a vital enzyme in the synthesis of messenger RNA (mRNA), microRNA, and small nuclear RNA...more
Number of Targets: 14
T3D3596Iodine
7553-56-2
I2
253.809 g/mol
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  • Cosmetic Toxin
  • Disinfectant
  • Food Toxin
  • Halogen
  • Household Toxin
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Metabolite
  • Natural Compound
  • Non-Metal
Iodide inhibits adenylate cyclase in thyroid gland follicle cells and decreases the TSH-induced rise in intracellular cAMP. This results in decreased iodination of thy...more
Number of Targets: 10
T3D3597Citrinin
518-75-2
C13H14O5
250.247 g/mol
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  • Ester
  • Ether
  • Food Toxin
  • Fungal Toxin
  • Industrial/Workplace Toxin
  • Lachrymator
  • Metabolite
  • Mycotoxin
  • Natural Compound
  • Organic Compound
Citrinin produces proximal tubular necrosis, but only after transport into proximal tubular cells. It utilizes the organic anion transporter for entry into the cells, ...more
Number of Targets: 28
T3D3598Aflatoxin B1
1162-65-8
C17H12O6
312.274 g/mol
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  • Ester
  • Ether
  • Food Toxin
  • Fungal Toxin
  • Metabolite
  • Mycotoxin
  • Natural Compound
  • Organic Compound
Aflatoxin B1 requires epoxidation to aflatoxin B1 2,3-oxide for activation, which is performed by cytochome P-450 enzymes CYP1A2 and CYP3A4. It produces DNA damage, ge...more
Number of Targets: 11
T3D35992-Aminophenol
95-55-6
C6H7NO
109.126 g/mol
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  • Amine
  • Aromatic Hydrocarbon
  • Cosmetic Toxin
  • Household Toxin
  • Industrial/Workplace Toxin
  • Organic Compound
  • Synthetic Compound
2-Aminophenol interacts with both adult and fetal hemoglobin, forming methemoglobin. In comparison to its isomers, 3-aminophenol and 4-aminophenol, 2-aminophenol is th...more
Number of Targets: 9
T3D36004-Aminophenol
123-30-8
C6H7NO
109.126 g/mol
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  • Amine
  • Aromatic Hydrocarbon
  • Cosmetic Toxin
  • Food Toxin
  • Household Toxin
  • Metabolite
  • Organic Compound
  • Synthetic Compound
4-Aminobiphenyl requires metabolic activation in order to exert its toxicity. This is catalyzed by N-hydroxylation via cytochrome P450 1A2, then followed by O-sulfatio...more
Number of Targets: 6
T3D36013-Aminophenol
591-27-5
C6H7NO
109.126 g/mol
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  • Amine
  • Aromatic Hydrocarbon
  • Cosmetic Toxin
  • Household Toxin
  • Natural Compound
  • Organic Compound
3-Aminophenol interacts with both adult and fetal hemoglobin, forming methemoglobin. In comparison to its isomers, 2-aminophenol and 4-aminophenol, 3-aminophenol is th...more
Number of Targets: 15
T3D3602Microcystin-LR
101043-37-2
Not Available
Not Available
T3d3602
  • Amide
  • Amine
  • Bacterial Toxin
  • Ether
  • Microcystin
  • Natural Compound
  • Organic Compound
  • Protein
The site of action of microcystins is the hepatocyte, the commonest cell type in the liver. They act by disrupting the cytoskeleton, the adaptable protein framework th...more
Number of Targets: 24
T3D3603Fumonisin B1
116355-83-0
C34H59NO15
721.830 g/mol
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  • Amine
  • Ester
  • Ether
  • Food Toxin
  • Fungal Toxin
  • Metabolite
  • Mycotoxin
  • Natural Compound
  • Organic Compound
Fumonisins are similar in structure to the long-chain base backbones of sphingolipids, allowing it to inhibit of the biosynthesis of sphingosine and more complex sphin...more
Number of Targets: 16
T3D3604Gliotoxin
67-99-2
C13H14N2O4S2
326.391 g/mol
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  • Amide
  • Amine
  • Fungal Toxin
  • Mycotoxin
  • Natural Compound
  • Organic Compound
Gliotoxin possesses immunosuppressive properties as it may suppress and cause apoptosis in certain types of cells of the immune system, including neutrophils, eosinop...more
Number of Targets: 12
T3D3605Ochratoxin A
303-47-9
C20H18ClNO6
403.813 g/mol
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  • Amide
  • Amine
  • Ester
  • Ether
  • Food Toxin
  • Fungal Toxin
  • Metabolite
  • Mycotoxin
  • Natural Compound
  • Organic Compound
  • Organochloride
Ochratoxin A has been shown to be weakly mutagenic, possibly by induction of oxidative DNA damage. The nephrotoxin ochratoxin A (OTA) causes a reduction of glomerular ...more
Number of Targets: 5
T3D3606Ochratoxin B
4825-86-9
C20H19NO6
369.368 g/mol
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  • Amide
  • Amine
  • Ester
  • Ether
  • Food Toxin
  • Fungal Toxin
  • Metabolite
  • Mycotoxin
  • Natural Compound
  • Organic Compound
Ochratoxin B is thought to inhibit the accumulation of cartilage proteoglycans and general protein synthesis in a concentration-related manner. (A2872)
Number of Targets: 0
T3D3607Ochratoxin C
4865-85-4
C22H22ClNO6
431.866 g/mol
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  • Amide
  • Amine
  • Ester
  • Ether
  • Food Toxin
  • Fungal Toxin
  • Metabolite
  • Mycotoxin
  • Natural Compound
  • Organic Compound
  • Organochloride
Ochratoxin A, a metabolite of Ochratoxin C, has been shown to be weakly mutagenic, possibly by induction of oxidative DNA damage. The nephrotoxin ochratoxin A (OTA) ca...more
Number of Targets: 3
T3D3608Microcystin-YR
101064-48-6
C52H72N10O13
1045.187 g/mol
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  • Amide
  • Amine
  • Bacterial Toxin
  • Ether
  • Microcystin
  • Natural Compound
  • Organic Compound
The site of action of microcystins is the hepatocyte, the commonest cell type in the liver. They act by disrupting the cytoskeleton, the adaptable protein framework th...more
Number of Targets: 23
Displaying toxin 2626 - 2650 of 3678 in total