Browsing Toxins
Displaying toxin 2551 - 2575 of 3678 in total
T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
---|---|---|---|---|---|
T3D3458 | 1-Pentene 109-67-1 | C5H10 70.133 g/mol |
| Petroleum distillates are central nervous system depressants and cause pulmonary damage. During metabolism. 1-pentene is oxidized at the double bond and excreted as th...more Number of Targets: 0 | |
T3D3459 | 2-Pentene 109-68-2 | C5H10 70.133 g/mol |
| Petroleum distillates are central nervous system depressants and cause pulmonary damage. (A600) Number of Targets: 0 | |
T3D3460 | 2-Methyl-2-butene 513-35-9 | C5H10 70.133 g/mol |
| Petroleum distillates are central nervous system depressants and cause pulmonary damage. (A600) Number of Targets: 0 | |
T3D3461 | 3-Methyl-1-butene 563-45-1 | C5H10 70.133 g/mol |
| Petroleum distillates are central nervous system depressants and cause pulmonary damage. (A600) Number of Targets: 0 | |
T3D3462 | 2-Methyl-1-butene 563-46-2 | C5H10 70.133 g/mol |
| Petroleum distillates are central nervous system depressants and cause pulmonary damage. (A600) Number of Targets: 0 | |
T3D3463 | 3-Methyl-2-pentene 922-62-3 | C6H12 84.160 g/mol |
| Petroleum distillates are central nervous system depressants and cause pulmonary damage. (A600) Number of Targets: 0 | |
T3D3464 | 2,4,4,-Trimethyl-1-pentene 107-39-1 | C8H16 112.213 g/mol |
| Petroleum distillates are central nervous system depressants and cause pulmonary damage. (A600) Number of Targets: 0 | |
T3D3465 | Cyclopentane 287-92-3 | C5H10 70.133 g/mol |
| Petroleum distillates are central nervous system depressants and cause pulmonary damage. (A600) Number of Targets: 0 | |
T3D3466 | Methylcyclopentane 96-37-7 | C6H12 84.160 g/mol |
| Petroleum distillates are central nervous system depressants and cause pulmonary damage. (A600) Number of Targets: 0 | |
T3D3467 | Cyclohexane 110-82-7 | C6H12 84.160 g/mol |
| Petroleum distillates are central nervous system depressants and cause pulmonary damage. (A600) Number of Targets: 1 | |
T3D3468 | Isopropylbenzene 98-82-8 | C9H12 120.192 g/mol |
| Petroleum distillates are central nervous system depressants and cause pulmonary damage. (A600) Number of Targets: 0 | |
T3D3469 | Polyvinyl acetate 9003-20-7 | C6H12O2 116.158 g/mol |
| Polyvinyl acetate usually contains trace amounts of its precursor, vinyl acetate. One of the metabolites of vinyl acetate, acetaldehyde, is a known animal carcinogen. ...more Number of Targets: 1 | |
T3D3470 | Ethenyl acetate 108-05-4 | C4H6O2 86.089 g/mol |
| One of the metabolites of vinyl acetate, acetaldehyde, is a known animal carcinogen. Acetaldehyde can form adducts with DNA, causing damage such as cross-links. (L1304...more Number of Targets: 1 | |
T3D3471 | Acetaldehyde 75-07-0 | C2H4O 44.053 g/mol |
| Acetaldehyde can form adducts with DNA, causing damage such as cross-links. (A354) Number of Targets: 1 | |
T3D3474 | 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine 28289-54-5 | C12H15N 173.254 g/mol |
| MPTP itself is not toxic, and as a lipophilic compound can cross the blood-brain barrier. Once inside the brain, MPTP is metabolized into the toxic cation 1-methyl-4-p...more Number of Targets: 1 | |
T3D3476 | Albendazole 54965-21-8 | C12H15N3O2S 265.331 g/mol |
| Albendazole causes degenerative alterations in the tegument and intestinal cells of the worm by binding to the colchicine-sensitive site of tubulin, thus inhibiting it...more Number of Targets: 4 | |
T3D3477 | Allopurinol 315-30-0 | C5H4N4O 136.112 g/mol |
| Allopurinol inhibits the enzyme xanthine oxidase, blocking the conversion of the oxypurines hypoxanthine and xanthine to uric acid. Elevated concentrations of oxypurin...more Number of Targets: 1 | |
T3D3480 | Atenolol 29122-68-7 | C14H22N2O3 266.336 g/mol |
| Like metoprolol, atenolol competes with sympathomimetic neurotransmitters such as catecholamines for binding at beta(1)-adrenergic receptors in the heart and vascular ...more Number of Targets: 2 | |
T3D3483 | Etidronic acid 7414-83-7 | C2H8O7P2 206.028 g/mol |
| Bisphosphonates, when attached to bone tissue, are absorbed by osteoclasts, the bone cells that breaks down bone tissue. Although the mechanism of action of non-nitrog...more Number of Targets: 4 | |
T3D3487 | Brimonidine 59803-98-4 | C11H10BrN5 292.135 g/mol |
| Brimonidine is an alpha adrenergic receptor agonist (primarily alpha-2). It has a peak ocular hypotensive effect occurring at two hours post-dosing. Fluorophotometric ...more Number of Targets: 3 | |
T3D3491 | Carisoprodol 78-44-4 | C12H24N2O4 260.330 g/mol |
| Carisoprodol is a central nervous system depressant that acts as a sedative and skeletal muscle relaxant. Rather than acting directly on skeletal muscle, carisoprodol ...more Number of Targets: 0 | |
T3D3492 | Cephalosporin 97519-39-6 | C15H14N4O6S2 410.425 g/mol |
| Ceftibuten exerts its bactericidal action by binding to essential target proteins of the bacterial cell wall. This binding leads to inhibition of cell-wall synthesis. Number of Targets: 1 | |
T3D3495 | Ciprofloxacin 85721-33-1 | C17H18FN3O3 331.342 g/mol |
| The bactericidal action of ciprofloxacin results from inhibition of the enzymes topoisomerase II (DNA gyrase) and topoisomerase IV, which are required for bacterial DN...more Number of Targets: 3 | |
T3D3497 | Clindamycin 18323-44-9 | C18H33ClN2O5S 424.983 g/mol |
| Systemic/vaginal clindamycin inhibits protein synthesis of bacteria by binding to the 50S ribosomal subunits of the bacteria. Specifically, it binds primarily to the 2...more Number of Targets: 0 | |
T3D3498 | Cyclosporin 59865-13-3 | C62H111N11O12 1202.611 g/mol |
| Cyclosporine binds to cyclophilin. The complex then inhibits calcineurin which is normally responsible for activating transcription of interleukin 2. Cyclosporine also...more Number of Targets: 7 |