Browsing Toxins By Category
Displaying toxin 2376 - 2400 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D2675 | Linezolid 165800-03-3 | C16H20FN3O4 337.346 g/mol |  |
| Linezolid targets the large 39S subunit of the mitochondrial ribosome thereby deactivation mitochondrial protein synthesis. As a result Linezolid is cytotoxic to the m...more Number of Targets: 6 |
| T3D4928 | Linoleic acid 60-33-3 | C18H32O2 280.446 g/mol |  |
| Not Available Number of Targets: 6 |
| T3D4518 | Linuron 330-55-2 | C9H10Cl2N2O2 249.094 g/mol |  |
| Linuron is a weak competitive inhibitor of androgen receptor binding and it inhibits androgen-induced gene expression in vitro. This may partially contribute to the ma...more Number of Targets: 9 |
| T3D4759 | Liothyronine 6893-02-3 | C15H12I3NO4 650.974 g/mol |  |
| The hormones, T4 and T3, are tyrosine-based hormones produced by the thyroid gland. Iodine is an important component in their synthesis. The major form of thyroid horm...more Number of Targets: 10 |
| T3D4234 | Lipopolysaccharide Not Available | C21H44NO9P 485.549 g/mol |  |
| Not Available Number of Targets: 0 |
| T3D2605 | Listeriolysin O 112627-82-4 | Not Available 58687.670 g/mol |  |
| Listeriolysin O is a thiol-activated cholesterol-dependent pore forming toxin protein. LLO is selectively activated within the acidic phagosomes of cells that have pha...more Number of Targets: 1 |
| T3D1538 | Lithium aluminate 12003-67-7 | AlLiO2 65.921 g/mol |  |
| The main target organs of aluminum are the central nervous system and bone. Aluminum binds with dietary phosphorus and impairs gastrointestinal absorption of phosphoru...more Number of Targets: 3 |
| T3D1503 | Lithium aluminium hydride 16853-85-3 | AlH4Li 37.954 g/mol |  |
| The main target organs of aluminum are the central nervous system and bone. Aluminum binds with dietary phosphorus and impairs gastrointestinal absorption of phosphoru...more Number of Targets: 3 |
| T3D1738 | Lithium bromide 7550-35-8 | BrLi 86.845 g/mol |  |
| Bromine is a powerful oxidizing agent and is able to release oxygen free radicals from the water in mucous membranes. These free radicals are also potent oxidizers and...more Number of Targets: 6 |
| T3D0715 | Lithium chromate 14307-35-8 | CrLi2O4 129.876 g/mol |  |
| Hexavalent chromium's carcinogenic effects are caused by its metabolites, pentavalent and trivalent chromium. The DNA damage may be caused by hydroxyl radicals produce...more Number of Targets: 5 |
| T3D0678 | Lithium cobalt oxide 12190-79-3 | CoLiO2 97.873 g/mol |  |
| Cobalt is believed to exhibit its toxicity through a oxidant-based and free radical-based processes. It produces oxygen radicals and may be oxidized to ionic cobalt, c...more Number of Targets: 35 |
| T3D1873 | Lithium hexafluoroantimonate(V) 18424-17-4 | F6LiSb 242.690 g/mol |  |
| The inhalation data suggests that the myocardium is a target of antimony toxicity. It is possible that antimony affects circulating glucose by interfering with enzymes...more Number of Targets: 20 |
| T3D3566 | Lithium nitrate 7790-69-4 | LiNO3 68.946 g/mol |  |
| Nitrate's toxicity is a result of it's conversion to nitrite once in the body. Nitrite causes the autocatalytic oxidation of oxyhemoglobin to hydrogen peroxide and met...more Number of Targets: 9 |
| T3D1916 | Lithium perchlorate 7791-03-9 | ClLiO4 106.392 g/mol |  |
| The primary and most sensitive target of the perchlorate anion (perchlorate) is the thyroid gland. Perchlorate inhibits the transport of iodide (I-) from the blood int...more Number of Targets: 2 |
| T3D1544 | Lithium tetrachloroaluminate 14024-11-4 | AlCl4Li 175.735 g/mol |  |
| The main target organs of aluminum are the central nervous system and bone. Aluminum binds with dietary phosphorus and impairs gastrointestinal absorption of phosphoru...more Number of Targets: 3 |
| T3D4963 | Lithocholic acid 434-13-9 | C24H40O3 376.573 g/mol |  |
| Not Available Number of Targets: 11 |
| T3D3767 | Lolitrem B 81771-19-9 | C42H55NO7 685.889 g/mol |  |
| The neurological effects of Lolitrem B are a result of its ability to inhibit large conductance calcium-activated potassium channels (BK channels). Lolitrem B binds to...more Number of Targets: 1 |
| T3D4700 | Lomustine 13010-47-4 | C9H16ClN3O2 233.695 g/mol |  |
| Lomustine is a highly lipophilic nitrosourea compound which undergoes hydrolysis in vivo to form reactive metabolites. These metabolites cause alkylation and cross-lin...more Number of Targets: 2 |
| T3D2625 | Lopap Not Available | Not Available 22432.280 g/mol |  |
| Lopap activates thrombin by cleavage of prothrombin, causing thrombus formation, fibrinogen depletion, uncoagulable blood, decreased platelet count, inhibition of coll...more Number of Targets: 0 |
| T3D4647 | Loprazolam 61197-73-7 | C23H21ClN6O3 464.904 g/mol |  |
| Benzodiazepines bind nonspecifically to benzodiazepine receptors BNZ1, which mediates sleep, and BNZ2, which affects affects muscle relaxation, anticonvulsant activity...more Number of Targets: 18 |
| T3D2796 | Loratadine 79794-75-5 | C22H23ClN2O2 382.883 g/mol |  |
| Loratadine competes with free histamine and exhibits specific, selective peripheral H1 antagonistic activity. This blocks the action of endogenous histamine, which sub...more Number of Targets: 3 |
| T3D2707 | Lorazepam 846-49-1 | C15H10Cl2N2O2 321.158 g/mol |  |
| Lorazepam binds to an allosteric site on GABA-A receptors, which are pentameric ionotropic receptors in the CNS. Binding potentiates the effects of the inhibitory neur...more Number of Targets: 20 |
| T3D4585 | Lormetazepam 848-75-9 | C16H12Cl2N2O2 335.185 g/mol |  |
| Benzodiazepines bind nonspecifically to benzodiazepine receptors BNZ1, which mediates sleep, and BNZ2, which affects affects muscle relaxation, anticonvulsant activity...more Number of Targets: 18 |
| T3D0860 | Lotaustralin 534-67-8 | C11H19NO6 261.272 g/mol |  |
| Organic nitriles decompose into cyanide ions both in vivo and in vitro. Consequently the primary mechanism of toxicity for organic nitriles is their production of toxi...more Number of Targets: 38 |
| T3D4787 | Lovastatin 75330-75-5 | C24H36O5 404.540 g/mol |  |
| Lovastatin is structurally similar to the HMG, a substituent of the endogenous substrate of HMG-CoA reductase. Lovastatin is a prodrug that is activated in vivo via hy...more Number of Targets: 10 |