Browsing Toxins By Category
Displaying toxin 2301 - 2325 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D2454 | L-Coprine 58919-61-2 | C8H14N2O4 202.208 g/mol |  |
| It metabolises to 1-aminocyclopropanol, a closely-related chemical to Disulfiram and exhibits the same mechanism of action: inhibition of the enzyme acetaldehyde dehyd...more Number of Targets: 8 |
| T3D4156 | L-Cysteine 52-90-4 | C3H7NO2S 121.158 g/mol |  |
| Uremic toxins such as cysteine are actively transported into the kidneys via organic ion transporters (especially OAT3). Increased levels of uremic toxins can stimulat...more Number of Targets: 20 |
| T3D3028 | L-Dopa 59-92-7 | C9H11NO4 197.188 g/mol |  |
| Striatal dopamine levels in symptomatic Parkinson's disease are decreased by 60 to 80%, striatal dopaminergic neurotransmission may be enhanced by exogenous supplement...more Number of Targets: 8 |
| T3D5002 | L-Dopachrome 89762-39-0 | C9H7NO4 193.158 g/mol |  | Not Available | Not Available Number of Targets: 0 |
| T3D4967 | L-Dopaquinone 110810-88-3 | C9H9NO4 195.172 g/mol |  |
| Not Available Number of Targets: 0 |
| T3D4296 | L-Glutamic acid 56-86-0 | C5H9NO4 147.129 g/mol |  |
| Glutamate activates both ionotropic and metabotropic glutamate receptors. The ionotropic ones being non-NMDA (AMPA and kainate) and NMDA receptors. Free glutamic acid ...more Number of Targets: 76 |
| T3D4319 | L-Glutamine 56-85-9 | C5H10N2O3 146.145 g/mol |  |
| Supplemental L-glutamine's possible immunomodulatory role may be accounted for in a number of ways. L-glutamine appears to play a major role in protecting the integrit...more Number of Targets: 3 |
| T3D4363 | L-Histidine 71-00-1 | C6H9N3O2 155.155 g/mol |  |
| Since the actions of supplemental L-histidine are unclear, any postulated mechanism is entirely speculative. However, some facts are known about L-histidine and some o...more Number of Targets: 5 |
| T3D4024 | L-Hypoglycin A 156-56-9 | C7H11NO2 141.168 g/mol |  |
| Generally, hypoglycin is an amino acid and chemically related to lysine. It competitively binds to enzymes used in the catabolism of lysine and is the reason why it an...more Number of Targets: 0 |
| T3D4364 | L-Isoleucine 73-32-5 | C6H13NO2 131.173 g/mol |  |
| (Applies to Valine, Leucine and Isoleucine) This group of essential amino acids are identified as the branched-chain amino acids, BCAAs. Because this arrangement of ca...more Number of Targets: 6 |
| T3D4253 | L-Lactic acid 79-33-4 | C3H6O3 90.078 g/mol |  |
| Accumulation of L-lactic acid in the body has been shown to be toxic. At times of lactic acidosis, when excess intracellular lactate is released into the blood, mainte...more Number of Targets: 1 |
| T3D4365 | L-Leucine 61-90-5 | C6H13NO2 131.173 g/mol |  |
| This group of essential amino acids are identified as the branched-chain amino acids, BCAAs. Because this arrangement of carbon atoms cannot be made by humans, these a...more Number of Targets: 10 |
| T3D4328 | L-Methionine 63-68-3 | C5H11NO2S 149.211 g/mol |  |
| The mechanism of the possible anti-hepatotoxic activity of L-methionine is not entirely clear. It is thought that metabolism of high doses of acetaminophen in the live...more Number of Targets: 5 |
| T3D4366 | L-Phenylalanine 63-91-2 | C9H11NO2 165.189 g/mol |  |
| Extremely high serum levels of phenylalanine are found in patients with the inborn error of metabolism (IEM) called Phenylketonuria (PKU). At pathological concentratio...more Number of Targets: 10 |
| T3D4411 | L-Proline 147-85-3 | C5H9NO2 115.131 g/mol |  |
| Glycogenic, by L-Proline oxidase in the kidney, it is ring-opened and is oxidized to form L-Glutamic acid. L-Ornithine and L-Glutamic acid are converted to L-Proline v...more Number of Targets: 23 |
| T3D4367 | L-Serine 56-45-1 | C3H7NO3 105.093 g/mol |  |
| L-Serine plays a role in cell growth and development (cellular proliferation). The conversion of L-serine to glycine by serine hydroxymethyltransferase results in the ...more Number of Targets: 8 |
| T3D4368 | L-Threonine 72-19-5 | C4H9NO3 119.119 g/mol |  |
| L-Threonine is a precursor to the amino acids glycine and serine. It acts as a lipotropic in controlling fat build-up in the liver. May help combat mental illness and ...more Number of Targets: 3 |
| T3D4369 | L-Tryptophan 73-22-3 | C11H12N2O2 204.225 g/mol |  |
| A number of important side reactions occur during the catabolism of tryptophan on the pathway to acetoacetate. The first enzyme of the catabolic pathway is an iron por...more Number of Targets: 7 |
| T3D4371 | L-Tyrosine 60-18-4 | C9H11NO3 181.189 g/mol |  |
| Tyrosine is produced in cells by hydroxylating the essential amino acid phenylalanine. This relationship is much like that between cysteine and methionine. Half of the...more Number of Targets: 5 |
| T3D4370 | L-Valine 72-18-4 | C5H11NO2 117.146 g/mol |  |
| (Applies to Valine, Leucine and Isoleucine) This group of essential amino acids are identified as the branched-chain amino acids, BCAAs. Because this arrangement of ca...more Number of Targets: 3 |
| T3D3517 | Labetalol 36894-69-6 | C19H24N2O3 328.406 g/mol |  |
| Labetalol has two asymmetric centers and therefore, exists as a molecular complex of two diastereoisomeric pairs. Dilevalol, the R,R' stereoisomer, makes up 25% of rac...more Number of Targets: 7 |
| T3D3869 | Lactofen 77501-63-4 | C19H15ClF3NO7 461.773 g/mol |  |
| Not Available Number of Targets: 22 |
| T3D2570 | Lamotrigine 84057-84-1 | C9H7Cl2N5 256.091 g/mol |  |
| One proposed mechanism of action of Lamotrigine, the relevance of which remains to be established in humans, involves an effect on sodium channels. in vitro pharmacolo...more Number of Targets: 10 |
| T3D1737 | Lanthanum(III) bromide 13536-79-3 | Br3La 378.617 g/mol |  |
| Bromine is a powerful oxidizing agent and is able to release oxygen free radicals from the water in mucous membranes. These free radicals are also potent oxidizers and...more Number of Targets: 6 |
| T3D4078 | Lasiocarpine 303-34-4 | C21H33NO7 411.489 g/mol |  |
| Lasiocarpine is toxic to liver cells but not to lung cells, which is unable to metabolize the pyrrolizidine alkaloids to pyrroles. The application of lasiocarpine to h...more Number of Targets: 0 |