Browsing Toxins By Category
Displaying toxin 2226 - 2250 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D1734 | Indium(III) bromide 13465-09-3 | Br3In 354.530 g/mol |  |
| Bromine is a powerful oxidizing agent and is able to release oxygen free radicals from the water in mucous membranes. These free radicals are also potent oxidizers and...more Number of Targets: 6 |
| T3D1835 | Indium(III) selenide 12056-07-4 | In2Se3 466.520 g/mol |  |
| Selenium readily substitutes for sulfur in biomolecules and in many biochemical reactions, especially when the concentration of selenium is high and the concentration ...more Number of Targets: 0 |
| T3D4152 | Indoleacetic acid 87-51-4 | C10H9NO2 175.184 g/mol |  |
| Uremic toxins such as indole-3-acetic acid are actively transported into the kidneys via organic ion transporters (especially OAT3). Increased levels of uremic toxins ...more Number of Targets: 7 |
| T3D2753 | Indomethacin 53-86-1 | C19H16ClNO4 357.788 g/mol |  |
| Antiinflammatory effects of Indomethacin are believed to be due to inhibition of cylooxygenase in platelets which leads to the blockage of prostaglandin synthesis. Ant...more Number of Targets: 29 |
| T3D3864 | Indoxacarb 173584-44-6 | C22H17ClF3N3O7 527.834 g/mol |  |
| It is thought that indoxacarb's aromatic metabolites biotransform to active intermediates that produce methemoglobin (A15207). The mechanism of indoxacarb-induced rena...more Number of Targets: 30 |
| T3D4158 | Indoxyl sulfate 487-94-5 | C8H7NO4S 213.210 g/mol |  |
| Uremic toxins such as Indoxyl sulfate are actively transported into the kidneys via organic ion transporters (especially OAT3). Increased levels of uremic toxins can s...more Number of Targets: 6 |
| T3D3514 | Infliximab 170277-31-3 | Not Available 36105.695 g/mol |  |
| Infliximab neutralizes the biological activity of TNFa by binding with high affinity to the soluble and transmembrane forms of TNFa and inhibits binding of TNFa with i...more Number of Targets: 3 |
| T3D4200 | Inodxyl glucuronide 35804-66-1 | C14H15NO7 309.271 g/mol |  |
| Uremic toxins such as indoxyl-beta-D-glucuronide are actively transported into the kidneys via organic ion transporters (especially OAT3). Increased levels of uremic t...more Number of Targets: 3 |
| T3D2477 | Insulin 11061-68-0 | Not Available 11980.795 g/mol |  |
| Insulin has a direct inhibitory effect on the lipase concerned with the mobilization of fattty acids. Insulin binds to a receptor on the surface of the target cell and...more Number of Targets: 56 |
| T3D3596 | Iodine 7553-56-2 | I2 253.809 g/mol |  |
| Iodide inhibits adenylate cyclase in thyroid gland follicle cells and decreases the TSH-induced rise in intracellular cAMP. This results in decreased iodination of thy...more Number of Targets: 10 |
| T3D0139 | Iodine-129 15046-84-1 | I 128.905 g/mol |  |
| Iodide inhibits adenylate cyclase in thyroid gland follicle cells and decreases the TSH-induced rise in intracellular cAMP. This results in decreased iodination of thy...more Number of Targets: 11 |
| T3D0132 | Iodine-131 10043-66-0 | I 130.906 g/mol |  |
| Iodide inhibits adenylate cyclase in thyroid gland follicle cells and decreases the TSH-induced rise in intracellular cAMP. This results in decreased iodination of thy...more Number of Targets: 11 |
| T3D3865 | Iodosulfuron-methyl-sodium 144550-36-7 | C14H13IN5NaO6S 529.242 g/mol |  |
| Not Available Number of Targets: 2 |
| T3D4798 | Iopanoic acid 96-83-3 | C11H12I3NO2 570.932 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D3866 | Iprodione 36734-19-7 | C13H13Cl2N3O3 330.167 g/mol |  |
| Not Available Number of Targets: 19 |
| T3D4697 | Iron 7439-89-6 | Fe 55.845 g/mol |  |
| Iron is necessary for the production of hemoglobin. Iron-deficiency can lead to decreased production of hemoglobin and a microcytic, hypochromic anemia. Number of Targets: 0 |
| T3D1320 | Iron cacodylate 5968-84-3 | C6H18As3FeO6 466.813 g/mol |  |
| Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co...more Number of Targets: 44 |
| T3D2412 | Iron phosphide 12023-53-9 | FeP 86.819 g/mol |  |
| Phosphine inhibits cytochrome c oxidase, preventing mitochondrial oxidative phosphorylation. This non-competitive inhibition prevents cellular respiration and leads to...more Number of Targets: 20 |
| T3D1735 | Iron(II) bromide 7789-46-0 | Br2Fe 215.653 g/mol |  |
| Bromine is a powerful oxidizing agent and is able to release oxygen free radicals from the water in mucous membranes. These free radicals are also potent oxidizers and...more Number of Targets: 6 |
| T3D1736 | Iron(III) bromide 10031-26-2 | Br3Fe 295.557 g/mol |  |
| Bromine is a powerful oxidizing agent and is able to release oxygen free radicals from the water in mucous membranes. These free radicals are also potent oxidizers and...more Number of Targets: 6 |
| T3D0704 | Iron(III) chromate 10294-52-7 | Cr3FeH3O12 406.850 g/mol |  |
| Hexavalent chromium's carcinogenic effects are caused by its metabolites, pentavalent and trivalent chromium. The DNA damage may be caused by hydroxyl radicals produce...more Number of Targets: 5 |
| T3D3563 | Iron(III) nitrate 10421-48-4 | FeN3O9 241.860 g/mol |  |
| Nitrate's toxicity is a result of it's conversion to nitrite once in the body. Nitrite causes the autocatalytic oxidation of oxyhemoglobin to hydrogen peroxide and met...more Number of Targets: 9 |
| T3D4517 | Isazofos 42509-80-8 | C9H17ClN3O3PS 313.741 g/mol |  |
| Isazofos is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholinestera...more Number of Targets: 16 |
| T3D4839 | Isoamyl butyrate 106-27-4 | C9H18O2 158.238 g/mol |  |
| Not Available Number of Targets: 2 |
| T3D0816 | Isobergapten 482-48-4 | C12H8O4 216.190 g/mol |  |
| Inhibits insect cytochrome P450 (L579). The mechanism of action many furocoumarins is based on their ability to form photoadducts with DNA and other cellular component...more Number of Targets: 3 |