Browsing Toxins By Category
Displaying toxin 2001 - 2025 of 3678 in total
T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
---|---|---|---|---|---|
T3D4820 | Finasteride 98319-26-7 | C23H36N2O2 372.544 g/mol |
| The mechanism of action of Finasteride is based on its preferential inhibition of Type II 5a-reductase through the formation of a stable complex with the enzyme. Inhib...more Number of Targets: 8 | |
T3D0798 | Fipronil 120068-37-3 | C12H4Cl2F6N4OS 437.148 g/mol |
| Fipronil blocks the passage of chloride ions through the GABA-regulated chloride channel, disrupting CNS activity. (T10) Organic nitriles decompose into cyanide ions b...more Number of Targets: 29 | |
T3D4924 | Flavone 525-82-6 | C15H10O2 222.239 g/mol |
| Not Available Number of Targets: 9 | |
T3D2556 | Flecainide 54143-55-4 | C17H20F6N2O3 414.343 g/mol |
| Flecainide acts on sodium channels on the neuronal cell membrane, limiting the spread of seizure activity and reducing seizure propagation. The antiarrhythmic actions ...more Number of Targets: 4 | |
T3D3840 | Fluazifop-butyl 69806-50-4 | C19H20F3NO4 383.362 g/mol |
| Not Available Number of Targets: 3 | |
T3D3841 | Fluazifop-P-butyl 79241-46-6 | C19H20F3NO4 383.362 g/mol |
| Not Available Number of Targets: 6 | |
T3D3842 | Fluazinam 79622-59-6 | C13H4Cl2F6N4O4 465.092 g/mol |
| Not Available Number of Targets: 30 | |
T3D2711 | Fluconazole 86386-73-4 | C13H12F2N6O 306.271 g/mol |
| Fluconazole interacts with 14-α demethylase, a cytochrome P-450 enzyme necessary to convert lanosterol to ergosterol. As ergosterol is an essential component of the fu...more Number of Targets: 4 | |
T3D1847 | Flucythrinate 70124-77-5 | C26H23F2NO4 451.462 g/mol |
| Pyrethroids exert their effect by prolonging the open phase of the sodium channel gates when a nerve cell is excited. They appear to bind to the membrane lipid phase i...more Number of Targets: 20 | |
T3D2983 | Flucytosine 2022-85-7 | C4H4FN3O 129.093 g/mol |
| Although the exact mode of action is unknown, it has been proposed that flucytosine acts directly on fungal organisms by competitive inhibition of purine and pyrimidin...more Number of Targets: 2 | |
T3D4736 | Fludarabine 75607-67-9 | C10H13FN5O7P 365.212 g/mol |
| Fludarabine phosphate is rapidly dephosphorylated to 2-fluoro-ara-A and then phosphorylated intracellularly by deoxycytidine kinase to the active triphosphate, 2-fluor...more Number of Targets: 4 | |
T3D4570 | Fludiazepam 3900-31-0 | C16H12ClFN2O 302.731 g/mol |
| Fludiazepam has similar action to diazepam, but binds with four times more affinity to benzodiazepine receptors than diazepam. Number of Targets: 18 | |
T3D4509 | Fludioxonil 131341-86-1 | C12H6F2N2O2 248.185 g/mol |
| Organic nitriles decompose into cyanide ions both in vivo and in vitro. Consequently the primary mechanism of toxicity for organic nitriles is their production of toxi...more Number of Targets: 19 | |
T3D3843 | Flufenacet 142459-58-3 | C14H13F4N3O2S 363.331 g/mol |
| Not Available Number of Targets: 6 | |
T3D3844 | Flufenpyr-ethyl 188489-07-8 | C16H13ClF4N2O4 408.732 g/mol |
| 'EP A does not have, at this time, available data to determine whether flufenpyr-ethyl has a common mechanism of toxicity with other substances.' (L2089) Number of Targets: 9 | |
T3D1848 | Flumethrin 69770-45-2 | C28H22Cl2FNO3 510.384 g/mol |
| Pyrethroids exert their effect by prolonging the open phase of the sodium channel gates when a nerve cell is excited. They appear to bind to the membrane lipid phase i...more Number of Targets: 19 | |
T3D4510 | Flumetralin 62924-70-3 | C16H12ClF4N3O4 421.731 g/mol |
| Not Available Number of Targets: 22 | |
T3D3845 | Flumetsulam 98967-40-9 | C12H9F2N5O2S 325.294 g/mol |
| Not Available Number of Targets: 1 | |
T3D3846 | Flumiclorac-pentyl 87546-18-7 | C21H23ClFNO5 423.862 g/mol |
| Not Available Number of Targets: 12 | |
T3D3847 | Flumioxazin 103361-09-7 | C19H15FN2O4 354.332 g/mol |
| Not Available Number of Targets: 4 | |
T3D3047 | Flunitrazepam 1622-62-4 | C16H12FN3O3 313.283 g/mol |
| Benzodiazepines bind nonspecifically to benzodiazepine receptors BNZ1, which mediates sleep, and BNZ2, which affects affects muscle relaxation, anticonvulsant activity...more Number of Targets: 21 | |
T3D4511 | Fluometuron 2164-17-2 | C10H11F3N2O 232.202 g/mol |
| Not Available Number of Targets: 7 | |
T3D0110 | Fluoranthene 206-44-0 | C16H10 202.251 g/mol |
| The ability of PAH's to bind to blood proteins such as albumin allows them to be transported throughout the body. Many PAH's induce the expression of cytochrome P450 e...more Number of Targets: 6 | |
T3D0625 | Fluorene 86-73-7 | C13H10 166.219 g/mol |
| The ability of PAH's to bind to blood proteins such as albumin allows them to be transported throughout the body. Many PAH's induce the expression of cytochrome P450 e...more Number of Targets: 3 | |
T3D4808 | Fluorescein 2321-07-5 | C20H12O5 332.306 g/mol |
| Fluorescein sodium is used extensively as a diagnostic tool in the field of ophthalmology. Fluorescein is a fluorescent compound or fluorophore having a maximum absorb...more Number of Targets: 6 |