Browsing Toxins By Category
Displaying toxin 1801 - 1825 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D3682 | Dihydrocytochalasin B 39156-67-7 | C28H37NO5 467.597 g/mol |  |
| Cytochalasins are known to bind to the barbed, fast growing plus ends of microfilaments, which then blocks both the assembly and disassembly of individual actin monome...more Number of Targets: 6 |
| T3D3683 | Dihydrocytochalasin B gamma-lactone 14110-71-5 | C29H39NO5 481.624 g/mol |  |
| Cytochalasins are known to bind to the barbed, fast growing plus ends of microfilaments, which then blocks both the assembly and disassembly of individual actin monome...more Number of Targets: 6 |
| T3D2750 | Dihydroergotamine 6190-39-2 | C33H37N5O5 583.677 g/mol |  |
| Two theories have been proposed to explain the efficacy of 5-HT1D receptor agonists in migraine: 1) activation of 5-HT1D receptors located on intracranial blood vessel...more Number of Targets: 12 |
| T3D2974 | Dihydrotachysterol 67-96-9 | C28H46O 398.664 g/mol |  |
| Once hydroxylated to 25-hydroxydihydrotachysterol, the modified drug binds to the vitamin D receptor. The bound form of the vitamin D receptor serves as a transcriptio...more Number of Targets: 1 |
| T3D4751 | Dihydrotestosterone 521-18-6 | C19H30O2 290.440 g/mol |  |
| Not Available Number of Targets: 7 |
| T3D4332 | Dihydrothymine 696-04-8 | C5H8N2O2 128.129 g/mol |  |
| Dihydropyrimidine dehydrogenase catalyzes the reduction of thymine to 5, 6-dihydrothymine then dihydropyrimidinase hydrolyzes 5, 6-dihydrothymine to N-carbamyl-b-alani...more Number of Targets: 0 |
| T3D4333 | Dihydrouracil 504-07-4 | C4H6N2O2 114.103 g/mol |  |
| Not Available Number of Targets: 0 |
| T3D1501 | Dihydroxyaluminium 13682-92-3 | C2H8AlNO4 137.071 g/mol |  |
| The main target organs of aluminum are the central nervous system and bone. Aluminum binds with dietary phosphorus and impairs gastrointestinal absorption of phosphoru...more Number of Targets: 7 |
| T3D4199 | Dihydroxyphenylalanine 63-84-3 | C9H11NO4 197.188 g/mol |  |
| Uremic toxins such as dihydroxyphenylalanine are actively transported into the kidneys via organic ion transporters (especially OAT3). Increased levels of uremic toxin...more Number of Targets: 3 |
| T3D3644 | Diisobutyl phthalate 84-69-5 | C16H22O4 278.344 g/mol |  |
| Phthalate esters are endocrine disruptors. They decrease foetal testis testosterone production and reduce the expression of steroidogenic genes by decreasing mRNA expr...more Number of Targets: 5 |
| T3D1528 | Diisobutylaluminium hydride 1191-15-7 | C8H19Al 142.218 g/mol |  |
| The main target organs of aluminum are the central nervous system and bone. Aluminum binds with dietary phosphorus and impairs gastrointestinal absorption of phosphoru...more Number of Targets: 3 |
| T3D3645 | Diisodecyl phthalate 26761-40-0 | C28H46O4 446.662 g/mol |  |
| Phthalate esters are endocrine disruptors. They decrease foetal testis testosterone production and reduce the expression of steroidogenic genes by decreasing mRNA expr...more Number of Targets: 4 |
| T3D3646 | Diisoheptyl phthalate 41451-28-9 | C22H34O4 362.503 g/mol |  |
| Phthalate esters are endocrine disruptors. They decrease foetal testis testosterone production and reduce the expression of steroidogenic genes by decreasing mRNA expr...more Number of Targets: 0 |
| T3D3647 | Diisohexyl phthalate 146-50-9 | C20H30O4 334.450 g/mol |  |
| Phthalate esters are endocrine disruptors. They decrease foetal testis testosterone production and reduce the expression of steroidogenic genes by decreasing mRNA expr...more Number of Targets: 0 |
| T3D3648 | Diisononyl phthalate 28553-12-0 | C26H42O4 418.609 g/mol |  |
| Phthalate esters are endocrine disruptors. They decrease foetal testis testosterone production and reduce the expression of steroidogenic genes by decreasing mRNA expr...more Number of Targets: 7 |
| T3D3649 | Diisooctyl phthalate 27554-26-3 | C24H38O4 390.556 g/mol |  |
| Phthalate esters are endocrine disruptors. They decrease foetal testis testosterone production and reduce the expression of steroidogenic genes by decreasing mRNA expr...more Number of Targets: 0 |
| T3D1467 | Diisopropylzinc 625-81-0 | C6H14Zn 151.584 g/mol |  |
| Anaemia results from the excessive absorption of zinc suppressing copper and iron absorption, most likely through competitive binding of intestinal mucosal cells. Unba...more Number of Targets: 1 |
| T3D3650 | Diisotridecyl phthalate 68515-47-9 | C34H58O4 530.822 g/mol |  |
| Phthalate esters are endocrine disruptors. They decrease foetal testis testosterone production and reduce the expression of steroidogenic genes by decreasing mRNA expr...more Number of Targets: 0 |
| T3D3651 | Diisoundecyl phthalate 85507-79-5 | C31H52O4 488.742 g/mol |  |
| Phthalate esters are endocrine disruptors. They decrease foetal testis testosterone production and reduce the expression of steroidogenic genes by decreasing mRNA expr...more Number of Targets: 0 |
| T3D2758 | Diltiazem 42399-41-7 | C22H26N2O4S 414.518 g/mol |  |
| Possibly by deforming the channel, inhibiting ion-control gating mechanisms, and/or interfering with the release of calcium from the sarcoplasmic reticulum, diltiazem,...more Number of Targets: 6 |
| T3D1140 | Dimanganese decacarbonyl 10170-69-1 | C10Mn2O10 389.977 g/mol |  |
| Manganese is a cellular toxicant that can impair transport systems, enzyme activities, and receptor functions. It primarily targets the central nervous system, particu...more Number of Targets: 5 |
| T3D0960 | Dimetan 122-15-6 | C11H17NO3 211.258 g/mol |  |
| Dimetan is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoylation of the active sites of...more Number of Targets: 2 |
| T3D3830 | Dimethenamid 87674-68-8 | C12H18ClNO2S 275.795 g/mol |  |
| Not Available Number of Targets: 13 |
| T3D0229 | Dimethoate 60-51-5 | C5H12NO3PS2 229.257 g/mol |  |
| Dimethoate is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholineste...more Number of Targets: 10 |
| T3D4495 | Dimethomorph 110488-70-5 | C21H22ClNO4 387.857 g/mol |  |
| Not Available Number of Targets: 20 |