Browsing Toxins By Category
Displaying toxin 1751 - 1775 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D1242 | Dibutyltin dichloride 683-18-1 | C8H18Cl2Sn 303.840 g/mol |  |
| Organotin compounds produce neurotoxic and immunotoxic effects. Organotins may directly activate glial cells contributing to neuronal cell degeneration by local releas...more Number of Targets: 18 |
| T3D1283 | Dibutyltin dilaurate 77-58-7 | C32H64O4Sn 631.560 g/mol |  |
| Organotin compounds produce neurotoxic and immunotoxic effects. Organotins may directly activate glial cells contributing to neuronal cell degeneration by local releas...more Number of Targets: 12 |
| T3D1246 | Dibutyltin hydride 1002-53-5 | C8H20Sn 234.950 g/mol |  |
| Organotin compounds produce neurotoxic and immunotoxic effects. Organotins may directly activate glial cells contributing to neuronal cell degeneration by local releas...more Number of Targets: 12 |
| T3D1259 | Dibutyltin oxide 818-08-6 | C8H18OSn 248.940 g/mol |  |
| Organotin compounds produce neurotoxic and immunotoxic effects. Organotins may directly activate glial cells contributing to neuronal cell degeneration by local releas...more Number of Targets: 12 |
| T3D0807 | Dicamba 1918-00-9 | C8H6Cl2O3 221.037 g/mol |  |
| Not Available Number of Targets: 5 |
| T3D4092 | Dicentrine 517-66-8 | C20H21NO4 339.385 g/mol |  |
| Dicentrine was found to be a potent alpha 1-adrenoceptor blocking agent in rat thoracic aorta as revealed by its competitive antagonism of noradrenaline- (pA2 = 8.19 +...more Number of Targets: 2 |
| T3D3823 | Dichloran 99-30-9 | C6H4Cl2N2O2 207.014 g/mol |  |
| Not Available Number of Targets: 12 |
| T3D0957 | Dichlormate 1966-58-1 | C9H9Cl2NO2 234.079 g/mol |  |
| Dichlormate is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoylation of the active site...more Number of Targets: 2 |
| T3D1589 | Dichloro(1,5-cyclooctadiene) palladium(II) 12107-56-1 | C8H8Cl2Pd 281.480 g/mol |  |
| Due to their ability to form strong complexes with both inorganic and organic ligands, palladium ions can disturb cellular equilibria, replace other essential ions, an...more Number of Targets: 6 |
| T3D4690 | Dichloroacetic Acid 79-43-6 | C2H2Cl2O2 128.942 g/mol |  |
| The dichloroacetate ion stimulates the activity of the enzyme pyruvate dehydrogenase by inhibiting the enzyme pyruvate dehydrogenase kinase. Thus, it decreases lactate...more Number of Targets: 1 |
| T3D1413 | Dichlorobis(ethylenediamine)nickel(II) 22980-82-1 | C4H16Cl2N4Ni 249.796 g/mol |  |
| Nickel is known to substitute for other essential elements in certain enzmes, such as calcineurin. It is genotoxic, and some nickel compounds have been shown to promot...more Number of Targets: 68 |
| T3D1545 | Dichloroethylaluminum 563-43-9 | C2H5AlCl2 126.949 g/mol |  |
| The main target organs of aluminum are the central nervous system and bone. Aluminum binds with dietary phosphorus and impairs gastrointestinal absorption of phosphoru...more Number of Targets: 3 |
| T3D0080 | Dichloromethane 1975-09-02 | CH2Cl2 84.933 g/mol |  |
| Methylene chloride targets the lungs, blood system, and nervous system. In the lungs its metabolites damage Clara cells. It is also metabolized into carbon monoxide, w...more Number of Targets: 11 |
| T3D2350 | Dichloromethoxydibenzofuran 107819-07-8 | C13H8Cl2O2 267.107 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D1869 | Dichlorotribenzylantimony 19493-17-5 | C21H21Cl2Sb 466.060 g/mol |  |
| The inhalation data suggests that the myocardium is a target of antimony toxicity. It is possible that antimony affects circulating glucose by interfering with enzymes...more Number of Targets: 20 |
| T3D0801 | Dichlorprop 120-36-5 | C9H8Cl2O3 235.064 g/mol |  |
| CDDs cause their toxic effects by binding to the aryl hydrocarbon receptor and subsequently altering the trascription of certain genes. The affinity for the Ah recepto...more Number of Targets: 6 |
| T3D0240 | Dichlorvos 62-73-7 | C4H7Cl2O4P 220.976 g/mol |  |
| Dichlorvos is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholineste...more Number of Targets: 7 |
| T3D4729 | Diclofenac 15307-86-5 | C14H11Cl2NO2 296.149 g/mol |  |
| The antiinflammatory effects of diclofenac are believed to be due to inhibition of both leukocyte migration and the enzyme cylooxygenase (COX-1 and COX-2), leading to ...more Number of Targets: 8 |
| T3D3824 | Diclofop-methyl 51338-27-3 | C16H14Cl2O4 341.186 g/mol |  |
| Not Available Number of Targets: 11 |
| T3D3825 | Diclosulam 145701-21-9 | C13H10Cl2FN5O3S 406.220 g/mol |  |
| Not Available Number of Targets: 7 |
| T3D0674 | Dicobalt edetate 36499-65-7 | C10H12Co2N2O8 406.077 g/mol |  |
| Cobalt is believed to exhibit its toxicity through a oxidant-based and free radical-based processes. It produces oxygen radicals and may be oxidized to ionic cobalt, c...more Number of Targets: 35 |
| T3D0675 | Dicobalt octacarbonyl 10210-68-1 | C8Co2O8 341.947 g/mol |  |
| Cobalt is believed to exhibit its toxicity through a oxidant-based and free radical-based processes. It produces oxygen radicals and may be oxidized to ionic cobalt, c...more Number of Targets: 35 |
| T3D0144 | Dicofol 115-32-2 | C14H9Cl5O 370.486 g/mol |  |
| Like other organochloride pesticides, dicofol is believed to act by at least four mechanisms, possibly all functioning simultaneously. It may reduce potassium transpor...more Number of Targets: 74 |
| T3D3826 | Dicrotophos 141-66-2 | C8H16NO5P 237.190 g/mol |  |
| Dicrotophos is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholinest...more Number of Targets: 5 |
| T3D4080 | Dictamnine 484-29-7 | C12H9NO2 199.205 g/mol |  |
| Dictamnine has been shown to be phototoxic to human cell lines (namely Jurkat T cells and HaCaT keratinocytes). Although it is less phototoxic than the structurally re...more Number of Targets: 0 |