Browsing Toxins By Category
Displaying toxin 1676 - 1700 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D1157 | D-Gluconic acid Mn(II) salt 6485-39-8 | C6H12O7 196.155 g/mol |  |
| Manganese is a cellular toxicant that can impair transport systems, enzyme activities, and receptor functions. It primarily targets the central nervous system, particu...more Number of Targets: 5 |
| T3D4356 | D-Glucose 50-99-7 | C6H12O6 180.156 g/mol |  |
| Very high serum levels of glucose are found in untreated diabetic (type I or type II) patients. Glucose in chronic excess causes toxic effects on the structure and fun...more Number of Targets: 33 |
| T3D3096 | D-Hyoscyamine 13269-35-7 | C17H23NO3 289.369 g/mol |  |
| Hyoscyamine is an anticholinergic, specifically an antimuscarinic, and works by blocking the action of acetylcholine at parasympathetic sites in smooth muscle, secreto...more Number of Targets: 6 |
| T3D4307 | D-Lactic acid 10326-41-7 | C3H6O3 90.078 g/mol |  |
| Not Available Number of Targets: 3 |
| T3D4926 | D-Xylose 58-86-6 | C5H10O5 150.130 g/mol |  |
| Not Available Number of Targets: 2 |
| T3D4689 | Dacarbazine 4342-03-4 | C6H10N6O 182.183 g/mol |  |
| The mechanism of action is not known, but appears to exert cytotoxic effects via its action as an alkylating agent. Other theories include DNA synthesis inhibition by ...more Number of Targets: 3 |
| T3D3964 | Daidzein 486-66-8 | C15H10O4 254.238 g/mol |  |
| Not Available Number of Targets: 10 |
| T3D3821 | Daminozide 1596-84-5 | C6H12N2O3 160.171 g/mol |  |
| Not Available Number of Targets: 2 |
| T3D2482 | Dapsone 80-08-0 | C12H12N2O2S 248.301 g/mol |  |
| Dapsone acts against bacteria and protozoa in the same way as sulphonamides, that is by inhibiting the synthesis of dihydrofolic acid through competition with para-ami...more Number of Targets: 3 |
| T3D3499 | Darifenacin 133099-04-4 | C28H30N2O2 426.550 g/mol |  |
| Darifenacin selectively antagonizes the muscarinic M3 receptor. M3 receptors are involved in contraction of human bladder and gastrointestinal smooth muscle, saliva pr...more Number of Targets: 5 |
| T3D2861 | Daunorubicin 20830-81-3 | C27H29NO10 527.520 g/mol |  |
| Daunorubicin has antimitotic and cytotoxic activity through a number of proposed mechanisms of action: Daunorubicin forms complexes with DNA by intercalation between b...more Number of Targets: 7 |
| T3D3822 | Dazomet 533-74-4 | C5H10N2S2 162.276 g/mol |  |
| Not Available Number of Targets: 13 |
| T3D0953 | Debacarb 62732-91-6 | C14H19N3O4 293.318 g/mol |  |
| Debacarb is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoylation of the active sites o...more Number of Targets: 2 |
| T3D4056 | Debromoaplysiatoxin 52423-28-6 | C32H48O10 592.718 g/mol |  |
| Debromoaplysiatoxin have the ability to evoke biological and biochemical responses in cells, and belong to the TPA (12-O-tetradecanoylphorbol 13-acetate) type tumor pr...more Number of Targets: 0 |
| T3D0598 | Decachlorobiphenyl 2051-24-3 | C12Cl10 498.658 g/mol |  |
| The mechanism of action varies with the specific PCB. Dioxin-like PCBs bind to the aryl hydrocarbon receptor, which disrupts cell function by altering the transcriptio...more Number of Targets: 7 |
| T3D4183 | Decanal 112-31-2 | C10H20O 156.265 g/mol |  |
| Uremic toxins such as decanal are actively transported into the kidneys via organic ion transporters (especially OAT3). Increased levels of uremic toxins can stimulate...more Number of Targets: 3 |
| T3D0954 | Decarbofuran 1563-67-3 | C11H13NO3 207.226 g/mol |  |
| Decarbofuran is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoylation of the active sit...more Number of Targets: 2 |
| T3D4242 | Dehydroepiandrosterone sulfate 651-48-9 | C19H28O5S 368.488 g/mol |  |
| Although it predominantly functions as an endogenous precursor to more potent androgens such as testosterone and dihydroxytestosterone, DHEA (which is produced from DH...more Number of Targets: 0 |
| T3D4567 | Delorazepam 2894-67-9 | C15H10Cl2N2O 305.159 g/mol |  |
| Benzodiazepines bind nonspecifically to benzodiazepine receptors BNZ1, which mediates sleep, and BNZ2, which affects affects muscle relaxation, anticonvulsant activity...more Number of Targets: 18 |
| T3D3077 | Delphinine 561-07-9 | C33H45NO9 599.712 g/mol |  |
| Delphinine acts as an allosteric modulator of voltage-gated sodium channels. (L1234) Number of Targets: 14 |
| T3D2658 | delta-Conotoxin (Conus striatus) Not Available | Not Available 9216.755 g/mol |  |
| delta-Conotoxins inhibit the inactivation of voltage-dependent sodium channels. (L1107) Number of Targets: 14 |
| T3D2612 | Delta-hemolysin 74838-20-3 | Not Available 2978.515 g/mol |  |
| Hemolysins consists mainly of beta-sheets forms heptameric units on the cellular membrane, producing a complete beta-barrel pore. This pore allows the exchange of mono...more Number of Targets: 0 |
| T3D0043 | delta-Hexachlorocyclohexane 319-86-8 | C6H6Cl6 290.830 g/mol |  |
| Hexachlorocyclohexane is a neurotoxin that interferes with GABA neurotransmitter function by interacting with the GABA-A receptor-chloride channel complex at the picro...more Number of Targets: 42 |
| T3D2801 | delta9-Tetrahydrocannabinol 1972-08-3 | C21H30O2 314.462 g/mol |  |
| The mechanism of action of marinol is not completely understood. It is thought that cannabinoid receptors in neural tissues may mediate the effects of dronabinol and o...more Number of Targets: 3 |
| T3D1035 | Deltamethrin 52918-63-5 | C22H19Br2NO3 505.199 g/mol |  |
| Both type I and type II pyrethroids exert their effect by prolonging the open phase of the sodium channel gates when a nerve cell is excited. They appear to bind to th...more Number of Targets: 26 |