Browsing Toxins By Category
Displaying toxin 1476 - 1500 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D1428 | Chromium(III) potassium sulfate 10141-00-1 | CrKO8S2 283.220 g/mol |  |
| Trivalent chromium may also form complexes with peptides, proteins, and DNA, resulting in DNA-protein crosslinks, DNA strand breaks, DNA-DNA interstrand crosslinks, ch...more Number of Targets: 5 |
| T3D1446 | Chromium(III) sulfate 10101-53-8 | Cr3H12O14S2 456.202 g/mol |  |
| Trivalent chromium may also form complexes with peptides, proteins, and DNA, resulting in DNA-protein crosslinks, DNA strand breaks, DNA-DNA interstrand crosslinks, ch...more Number of Targets: 5 |
| T3D1448 | Chromium(III) sulfide 12018-22-3 | Cr2S3 200.187 g/mol |  |
| Trivalent chromium may also form complexes with peptides, proteins, and DNA, resulting in DNA-protein crosslinks, DNA strand breaks, DNA-DNA interstrand crosslinks, ch...more Number of Targets: 5 |
| T3D1449 | Chromium(IV) oxide 12018-01-8 | CrO2 83.995 g/mol |  |
| Trivalent chromium may also form complexes with peptides, proteins, and DNA, resulting in DNA-protein crosslinks, DNA strand breaks, DNA-DNA interstrand crosslinks, ch...more Number of Targets: 5 |
| T3D0065 | Chromium(VI) oxide 1333-82-0 | CrO3 99.994 g/mol |  |
| Hexavalent chromium's carcinogenic effects are caused by its metabolites, pentavalent and trivalent chromium. The DNA damage may be caused by hydroxyl radicals produce...more Number of Targets: 5 |
| T3D1450 | Chromocene 1271-24-5 | C10H10Cr 182.183 g/mol |  |
| Trivalent chromium may also form complexes with peptides, proteins, and DNA, resulting in DNA-protein crosslinks, DNA strand breaks, DNA-DNA interstrand crosslinks, ch...more Number of Targets: 5 |
| T3D1451 | Chromyl chloride 14977-61-8 | Cl2CrO2 154.901 g/mol |  |
| Trivalent chromium may also form complexes with peptides, proteins, and DNA, resulting in DNA-protein crosslinks, DNA strand breaks, DNA-DNA interstrand crosslinks, ch...more Number of Targets: 5 |
| T3D0137 | Chrysene 218-01-9 | C18H12 228.288 g/mol |  |
| The ability of PAH's to bind to blood proteins such as albumin allows them to be transported throughout the body. Many PAH's induce the expression of cytochrome P450 e...more Number of Targets: 5 |
| T3D0119 | Chrysotile asbestos 12001-29-5 | Mg3Si2O5(OH)4 Not Available |  |
| When asbestos fibers are inhaled, many are deposited on the epithelial surface of the respiratory tree. Fibers that are retained in the lung or mesothelium for long pe...more Number of Targets: 1 |
| T3D3012 | Ciclopirox 29342-05-0 | C12H17NO2 207.269 g/mol |  |
| Unlike antifungals such as itraconazole and terbinafine, which affect sterol synthesis, ciclopirox is thought to act through the chelation of polyvalent metal cations,...more Number of Targets: 5 |
| T3D3076 | Cicutoxin 505-75-9 | C17H22O2 258.355 g/mol |  |
| Cicutoxin is a cholinergic poison and disrupts the central nervous system. It does this by acting as a non-competitive antagonist at the GABA receptor. (L1232) Number of Targets: 19 |
| T3D2463 | Ciguatoxin 1 11050-21-8 | C60H86O19 1111.313 g/mol |  |
| Ciguatoxin lowers the threshold for opening voltage-gated sodium channels in synapses of the nervous system. The effect of opening a sodium channel will cause depolari...more Number of Targets: 14 |
| T3D2464 | Ciguatoxin 2 142185-85-1 | C60H86O18 1095.314 g/mol |  |
| Ciguatoxin lowers the threshold for opening voltage-gated sodium channels in synapses of the nervous system. The effect of opening a sodium channel will cause depolari...more Number of Targets: 14 |
| T3D2466 | Ciguatoxin 4B 123676-76-6 | C60H84O16 1061.299 g/mol |  |
| Ciguatoxin lowers the threshold for opening voltage-gated sodium channels in synapses of the nervous system. The effect of opening a sodium channel will cause depolari...more Number of Targets: 14 |
| T3D2810 | Cimetidine 51481-61-9 | C10H16N6S 252.339 g/mol |  |
| Cimetidine binds to an H2-receptor located on the basolateral membrane of the gastric parietal cell, blocking histamine effects. This competitive inhibition results in...more Number of Targets: 5 |
| T3D1853 | Cinerin I 25402-06-6 | C20H28O3 316.435 g/mol |  |
| Pyrethrins exert their effect by prolonging the open phase of the sodium channel gates when a nerve cell is excited. They appear to bind to the membrane lipid phase in...more Number of Targets: 20 |
| T3D1854 | Cinerin II 121-20-0 | C21H28O5 360.444 g/mol |  |
| Pyrethrins exert their effect by prolonging the open phase of the sodium channel gates when a nerve cell is excited. They appear to bind to the membrane lipid phase in...more Number of Targets: 20 |
| T3D3810 | Cinmethylin 87818-31-3 | C18H26O2 274.398 g/mol |  |
| Cinmethylin is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholinest...more Number of Targets: 9 |
| T3D4985 | Cinnamaldehyde 104-55-2 | C9H8O 132.159 g/mol |  |
| Cinnamaldehyde is an allergen. The physiologic effect of cinnamaldehyde is by means of increased histamine release and cell-mediated immunity. Number of Targets: 2 |
| T3D2535 | Cinobufagin 470-37-1 | C26H34O6 442.545 g/mol |  |
| Cinobufagin blocks the sodium/potassium pump in heart tissue. (L1083, L1084) Number of Targets: 0 |
| T3D3056 | Cinolazepam 75696-02-5 | C18H13ClFN3O2 357.766 g/mol |  |
| Cinolazepam binds to central benzodiazepine receptors which interact allosterically with GABA receptors. This potentiates the effects of the inhibitory neurotransmitte...more Number of Targets: 18 |
| T3D3495 | Ciprofloxacin 85721-33-1 | C17H18FN3O3 331.342 g/mol |  |
| The bactericidal action of ciprofloxacin results from inhibition of the enzymes topoisomerase II (DNA gyrase) and topoisomerase IV, which are required for bacterial DN...more Number of Targets: 3 |
| T3D1906 | cis-1,3-Dichloropropene 10061-01-5 | C3H4Cl2 110.970 g/mol |  |
| The primary toxic effects of cis-1,3-dichloropropene are portal-of-entry effects resulting from the chemical reactivity of the compound and its physicochemical propert...more Number of Targets: 3 |
| T3D0059 | cis-Chlordane 5103-71-9 | C10H6Cl8 409.779 g/mol |  |
| Chlordane is believed to bind irreversibly to DNA, leading to cell death or altered cellular function. It also affects transcription by antagonizing estrogen-related r...more Number of Targets: 14 |
| T3D4866 | cis-Citral 5392-40-5 | C10H16O 152.233 g/mol |  |
| Not Available Number of Targets: 1 |