Browsing Toxins By Category
Displaying toxin 1426 - 1450 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D3557 | Chlorine nitrate 14545-72-3 | ClNO3 97.458 g/mol |  |
| Nitrate's toxicity is a result of it's conversion to nitrite once in the body. Nitrite causes the autocatalytic oxidation of oxyhemoglobin to hydrogen peroxide and met...more Number of Targets: 9 |
| T3D3009 | Chlormezanone 80-77-3 | C11H12ClNO3S 273.736 g/mol |  |
| Chlormezanone binds to central benzodiazepine receptors which interact allosterically with GABA receptors. This potentiates the effects of the inhibitory neurotransmit...more Number of Targets: 1 |
| T3D4898 | Chloroacetaldehyde 107-20-0 | C2H3ClO 78.498 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D0104 | Chlorobenzene 108-90-7 | C6H5Cl 112.557 g/mol |  |
| The reactive metabolites of chlorobenzene are believed to bind both liver and kidney proteins, causing direct damage. Chlorobenzene also activates nuclear factor-kappa...more Number of Targets: 38 |
| T3D1553 | Chlorodiethyaluminum 96-10-6 | C4H10AlCl 120.557 g/mol |  |
| The main target organs of aluminum are the central nervous system and bone. Aluminum binds with dietary phosphorus and impairs gastrointestinal absorption of phosphoru...more Number of Targets: 3 |
| T3D0183 | Chloroethane 75-00-3 | C2H5Cl 64.514 g/mol |  |
| Chloroethane targets the central nervous system and the heart. The lipophilicity of chloroethane suggests it acts upon the lipid layer of cellular membrane or the hydr...more Number of Targets: 2 |
| T3D1863 | Chlorofluorotrimethylantimony 13077-54-8 | C3H9ClFSb 221.310 g/mol |  |
| The inhalation data suggest that the myocardium is a target of antimony toxicity. It is possible that antimony affects circulating glucose by interfering with enzymes ...more Number of Targets: 20 |
| T3D0011 | Chloroform 67-66-3 | CHCl3 119.378 g/mol |  |
| Chloroform and the reactive intermediates of chloroform metabolism, especially phosgene, bind covalently and irreversibly to cellular macromolecules and cause cellular...more Number of Targets: 41 |
| T3D1864 | Chlorohydroxytriphenylantimony 36368-97-5 | C18H16ClOSb 405.530 g/mol |  |
| The inhalation data suggest that the myocardium is a target of antimony toxicity. It is possible that antimony affects circulating glucose by interfering with enzymes ...more Number of Targets: 20 |
| T3D4685 | Chloromethyl methyl ether 107-30-2 | C2H5ClO 80.514 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D3807 | Chloroneb 2675-77-6 | C8H8Cl2O2 207.054 g/mol |  |
| Not Available Number of Targets: 6 |
| T3D1188 | Chlorophyllin 11006-34-1 | C34H34MgN4O6 618.962 g/mol |  |
| Excess copper is sequestered within hepatocyte lysosomes, where it is complexed with metallothionein. Copper hepatotoxicity is believed to occur when the lysosomes bec...more Number of Targets: 6 |
| T3D4655 | Chloropicrin 76-06-2 | CCl3NO2 164.375 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D3003 | Chloroprocaine 133-16-4 | C13H19ClN2O2 270.755 g/mol |  |
| Chloroprocaine acts mainly by inhibiting sodium influx through voltage gated sodium channels in the neuronal cell membrane of peripheral nerves. When the influx of sod...more Number of Targets: 5 |
| T3D2561 | Chloroquine 54-05-7 | C18H26ClN3 319.872 g/mol |  |
| The mechanism of plasmodicidal action of chloroquine is not completely certain. Like other quinoline derivatives, it is thought to inhibit heme polymerase activity. Th...more Number of Targets: 6 |
| T3D1660 | Chlorosulfonyl isocyanate 1189-71-5 | CClNO3S 141.534 g/mol |  |
| Cyanide is an inhibitor of cytochrome c oxidase in the fourth complex of the electron transport chain (found in the membrane of the mitochondria of eukaryotic cells). ...more Number of Targets: 39 |
| T3D1700 | Chlorothalonil 1897-45-6 | C8Cl4N2 265.911 g/mol |  |
| Organic nitriles decompose into cyanide ions both in vivo and in vitro. Consequently the primary mechanism of toxicity for organic nitriles is their production of toxi...more Number of Targets: 84 |
| T3D2508 | Chlorotoxin 163515-35-3 | Not Available 4004.725 g/mol |  |
| Chlorotoxin blocks small conductance chloride channels. (L1043) Number of Targets: 15 |
| T3D2989 | Chlorpheniramine 132-22-9 | C16H19ClN2 274.788 g/mol |  |
| Chlorpheniramine binds to the histamine H1 receptor. This blocks the action of endogenous histamine, which subsequently leads to temporary relief of the negative sympt...more Number of Targets: 13 |
| T3D0948 | Chlorprocarb 23121-99-5 | C13H18N2O4 266.293 g/mol |  |
| Chlorprocarb is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoylation of the active sit...more Number of Targets: 2 |
| T3D2806 | Chlorpromazine 50-53-3 | C17H19ClN2S 318.864 g/mol |  |
| Chlorpromazine acts as an antagonist (blocking agent) on different postsysnaptic receptors -on dopaminergic-receptors (subtypes D1, D2, D3 and D4 - different antipsych...more Number of Targets: 40 |
| T3D0949 | Chlorpropham 101-21-3 | C10H12ClNO2 213.661 g/mol |  |
| Chlorpropham is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoylation of the active sit...more Number of Targets: 12 |
| T3D3031 | Chlorprothixene 113-59-7 | C18H18ClNS 315.860 g/mol |  |
| Chlorprothixene blocks postsynaptic mesolimbic dopaminergic D1 and D2 receptors in the brain; depresses the release of hypothalamic and hypophyseal hormones and is bel...more Number of Targets: 16 |
| T3D0127 | Chlorpyrifos 2921-88-2 | C9H11Cl3NO3PS 350.586 g/mol |  |
| Chlorpyrifos is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholines...more Number of Targets: 55 |
| T3D4485 | Chlorpyrifos oxon 5598-15-2 | C9H11Cl3NO4P 334.521 g/mol |  |
| Chlorpyrifos oxon is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcho...more Number of Targets: 22 |