Browsing Toxins By Category
Displaying toxin 876 - 900 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D3672 | Aflatoxin M2 6885-57-0 | C17H14O7 330.289 g/mol |  |
| Aflatoxins produce singlet oxygen upon their exposure to UV (365-nm) light. Singlet oxygen in turn activates them to mutagens and DNA binding species. Aflatoxin metabo...more Number of Targets: 3 |
| T3D3726 | Aflatrem 70553-75-2 | C32H39NO4 501.656 g/mol |  |
| Tremorgenic mycotoxins exert their toxic effects by interfering with neurotransmitter release, possibly by causing degeneration of nerve terminals. They are thought to...more Number of Targets: 26 |
| T3D2506 | Agitoxin 155646-21-2 | Not Available 4020.835 g/mol |  |
| Agitoxin binds to and blocks the Shaker potassium channel in Drosophila as well as to its mammalian homologue. (A157) Number of Targets: 8 |
| T3D3692 | Agroclavine 548-42-5 | C16H18N2 238.328 g/mol |  |
| Ergoline alkaloids tend to act as a group, producing complex and variable effects of partial agonism or antagonism at adrenergic, dopaminergic, and serotonergic recept...more Number of Targets: 6 |
| T3D0810 | Alachlor 15972-60-8 | C14H20ClNO2 269.767 g/mol |  |
| Its mode of action is elongase inhibition, and inhibition of geranylgeranyl pyrophosphate (GGPP) cyclisation enzymes. It is also know to inhibit biosynthesis of fatty...more Number of Targets: 26 |
| T3D0916 | Alanycarb 83130-01-2 | C17H25N3O4S2 399.528 g/mol |  |
| Alanycarb is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoylation of the active sites ...more Number of Targets: 2 |
| T3D3476 | Albendazole 54965-21-8 | C12H15N3O2S 265.331 g/mol |  |
| Albendazole causes degenerative alterations in the tegument and intestinal cells of the worm by binding to the colchicine-sensitive site of tubulin, thus inhibiting it...more Number of Targets: 4 |
| T3D3098 | Alcuronium 23214-96-2 | C44H50Br2N4O2 826.701 g/mol |  |
| Curare is a non-depolarizing muscle relaxant that acts as a competitive antagonist at the nicotinic acetylcholine receptors. (L1256) Number of Targets: 17 |
| T3D0919 | Aldicarb 116-06-3 | C7H14N2O2S 190.263 g/mol |  |
| Aldicarb is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoylation of the active sites o...more Number of Targets: 12 |
| T3D0918 | Aldicarb sulfoxide 1646-87-3 | C7H14N2O3S 206.263 g/mol |  |
| Aldicarb sulfoxide is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoylation of the acti...more Number of Targets: 3 |
| T3D0920 | Aldoxycarb 1646-88-4 | C7H14N2O4S 222.262 g/mol |  |
| Aldoxycarb is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoylation of the active sites...more Number of Targets: 2 |
| T3D0024 | Aldrin 309-00-2 | C12H8Cl6 364.910 g/mol |  |
| Aldrin antagonizes the action of the neurotransmitter gamma-aminobutyric acid (GABA) acting at the GABA-A receptors, effectively blocking the GABA-induced uptake of ch...more Number of Targets: 41 |
| T3D2666 | Alendronic acid 66376-36-1 | C4H13NO7P2 249.096 g/mol |  |
| The action of Alendronate on bone tissue is based partly on its affinity for hydroxyapatite, which is part of the mineral matrix of bone. Alendronate also targets farn...more Number of Targets: 7 |
| T3D2894 | Alfentanil 71195-58-9 | C21H32N6O3 416.517 g/mol |  |
| Opiate receptors are coupled with G-protein receptors and function as both positive and negative regulators of synaptic transmission via G-proteins that activate effec...more Number of Targets: 6 |
| T3D4936 | Allantoin 97-59-6 | C4H6N4O3 158.115 g/mol |  |
| Not Available Number of Targets: 2 |
| T3D1024 | Allethrin 584-79-2 | C19H26O3 302.408 g/mol |  |
| Both type I and type II pyrethroids exert their effect by prolonging the open phase of the sodium channel gates when a nerve cell is excited. They appear to bind to th...more Number of Targets: 36 |
| T3D2531 | Allopumiliotoxin 73376-38-2 | C16H29NO2 267.407 g/mol |  |
| Allopumiliotoxins may affect sodium and potassium channels in cells and inhibit calcium-dependent ATPase. (L1077, A313, A315) Number of Targets: 11 |
| T3D3477 | Allopurinol 315-30-0 | C5H4N4O 136.112 g/mol |  |
| Allopurinol inhibits the enzyme xanthine oxidase, blocking the conversion of the oxypurines hypoxanthine and xanthine to uric acid. Elevated concentrations of oxypurin...more Number of Targets: 1 |
| T3D4860 | Allura red AC 25956-17-6 | C18H16N2O8S2 452.458 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D1774 | Allyl bromide 106-95-6 | C3H5Br 120.976 g/mol |  |
| Organobromide compounds such as allylbromide are strong alkylating agents. Consequently they can readily modify free thiols (cysteines) and methionine residues of the...more Number of Targets: 3 |
| T3D0778 | Allyl isothiocyanate 57-06-7 | C4H5NS 99.154 g/mol |  |
| Cyanide is an inhibitor of cytochrome c oxidase in the fourth complex of the electron transport chain (found in the membrane of the mitochondria of eukaryotic cells). ...more Number of Targets: 41 |
| T3D1572 | Allylpalladium chloride dimer 12012-95-2 | C6H6Cl2Pd2 361.860 g/mol |  |
| Due to their ability to form strong complexes with both inorganic and organic ligands, palladium ions can disturb cellular equilibria, replace other essential ions, an...more Number of Targets: 6 |
| T3D0921 | Allyxycarb 6392-46-7 | C16H22N2O2 274.358 g/mol |  |
| Allyxycarb is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoylation of the active sites...more Number of Targets: 2 |
| T3D2931 | Almotriptan 181183-52-8 | C17H25N3O2S 335.464 g/mol |  |
| Almotriptan binds with high affinity to human 5-HT1B and 5-HT1D receptors leading to cranial blood vessel constriction. Number of Targets: 2 |
| T3D2626 | alpha-Agatoxin 128549-96-2 | C26H47N7O2 489.697 g/mol |  |
| alpha-Agatoxins block the glutamate-activated receptor channels in the neuronal postsynaptic terminals of insects and mammals, preventing excitory junction potential f...more Number of Targets: 11 |