Browsing Toxins By Category
Displaying toxin 851 - 875 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D3700 | Acetyldeoxynivalenol 50722-38-8 | C17H22O7 338.352 g/mol |  |
| Unlike many other mycotoxins, trichothecenes do not require metabolic activation to exert their biological activity, instead directly reacting with cellular components...more Number of Targets: 2 |
| T3D3789 | Acibenzolar-S-Methyl 135158-54-2 | C8H6N2OS2 210.276 g/mol |  |
| Not Available Number of Targets: 4 |
| T3D4858 | Acid yellow 23 1934-21-0 | C16H9N4Na3O9S2 534.363 g/mol |  |
| Not Available Number of Targets: 2 |
| T3D3790 | Acifluorfen 50594-66-6 | C14H7ClF3NO5 361.657 g/mol |  |
| Not Available Number of Targets: 10 |
| T3D3078 | Aconitine 302-27-2 | C34H47NO11 645.737 g/mol |  |
| Aconitine opens voltage-gated sodium channed in the heart and other tissues. (L1235) Number of Targets: 14 |
| T3D0633 | Acridine 260-94-6 | C13H9N 179.217 g/mol |  |
| The ability of PAH's to bind to blood proteins such as albumin allows them to be transported throughout the body. Many PAH's induce the expression of cytochrome P450 e...more Number of Targets: 3 |
| T3D1029 | Acrinathrin 101007-06-1 | C26H21F6NO5 541.439 g/mol |  |
| Both type I and type II pyrethroids exert their effect by prolonging the open phase of the sodium channel gates when a nerve cell is excited. They appear to bind to th...more Number of Targets: 19 |
| T3D0037 | Acrolein 107-02-8 | C3H4O 56.063 g/mol |  |
| Acrolein rapidly and irreversibly binds to lysine moieties and sulfhydryl groups found on many cellular molecules forming thiol ethers. By this mechanism acrolein can ...more Number of Targets: 29 |
| T3D2573 | Acrylamide 1979-06-01 | C3H5NO 71.078 g/mol |  |
| Acrylamide produces a central-peripheral distal axonopathy when administered chronically. This is characterized functionally by decreases in the monosynaptic reflex an...more Number of Targets: 50 |
| T3D1688 | Acrylonitrile 107-13-1 | C3H3N 53.063 g/mol |  |
| Organic nitriles decompose into cyanide ions both in vivo and in vitro. Consequently the primary mechanism of toxicity for organic nitriles is their production of toxi...more Number of Targets: 39 |
| T3D0230 | Actinium-227 14952-40-0 | Ac 227.028 g/mol |  |
| The ionizing radiation produced by actinium causes cellular damage that includes DNA breakage, accurate or inaccurate repair, apoptosis, gene mutations, chromosomal ch...more Number of Targets: 1 |
| T3D0794 | Actinolite Asbestos 77536-66-4 | (Na, K)0-1Ca2(Mg, Fe)5Si8O22(OH)2 Not Available |  |
| When asbestos fibers are inhaled, many are deposited on the epithelial surface of the respiratory tree. Fibers that are retained in the lung or mesothelium for long pe...more Number of Targets: 1 |
| T3D0275 | Adamsite 578-94-9 | C12H9AsClN 277.581 g/mol |  |
| Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co...more Number of Targets: 45 |
| T3D4673 | Adapalene 106685-40-9 | C28H28O3 412.520 g/mol |  |
| Mechanistically, adapalene binds to specific retinoic acid nuclear receptors (gamma and beta) and retinoid X receptors but does not bind to the cytosolic receptor prot...more Number of Targets: 6 |
| T3D4279 | Adenine 73-24-5 | C5H5N5 135.127 g/mol |  |
| Adenine forms adenosine, a nucleoside, when attached to ribose, and deoxyadenosine when attached to deoxyribose, and it forms adenosine triphosphate (ATP), a nucleotid...more Number of Targets: 10 |
| T3D4275 | Adenosine 58-61-7 | C10H13N5O4 267.241 g/mol |  |
| Adenosine slows conduction time through the AV node and can interrupt the reentry pathways through the AV node, resulting in the restoration of normal sinus rhythm in ...more Number of Targets: 11 |
| T3D4276 | Adenosine triphosphate 56-65-5 | C10H16N5O13P3 507.181 g/mol |  |
| ATP is able to store and transport chemical energy within cells. ATP also plays an important role in the synthesis of nucleic acids. ATP can be produced by various cel...more Number of Targets: 42 |
| T3D0672 | Adenosylcobalamin 13870-90-1 | C72H100CoN18O17P 1579.582 g/mol |  |
| Cobalt is believed to exhibit its toxicity through a oxidant-based and free radical-based processes. It produces oxygen radicals and may be oxidized to ionic cobalt, c...more Number of Targets: 35 |
| T3D1689 | Adiponitrile 111-69-3 | C6H8N2 108.141 g/mol |  |
| Organic nitriles decompose into cyanide ions both in vivo and in vitro. Consequently the primary mechanism of toxicity for organic nitriles is their production of toxi...more Number of Targets: 39 |
| T3D3725 | Aflatoxicol 29611-03-8 | C17H14O6 314.290 g/mol |  |
| Aflatoxins produce singlet oxygen upon their exposure to UV (365-nm) light. Singlet oxygen in turn activates them to mutagens and DNA binding species. Aflatoxin metabo...more Number of Targets: 1 |
| T3D3598 | Aflatoxin B1 1162-65-8 | C17H12O6 312.274 g/mol |  |
| Aflatoxin B1 requires epoxidation to aflatoxin B1 2,3-oxide for activation, which is performed by cytochome P-450 enzymes CYP1A2 and CYP3A4. It produces DNA damage, ge...more Number of Targets: 11 |
| T3D3669 | Aflatoxin B2 7220-81-7 | C17H14O6 314.290 g/mol |  |
| Aflatoxins produce singlet oxygen upon their exposure to UV (365-nm) light. Singlet oxygen in turn activates them to mutagens and DNA binding species. Aflatoxin metabo...more Number of Targets: 3 |
| T3D3670 | Aflatoxin G 1165-39-5 | C17H12O7 328.273 g/mol |  |
| Aflatoxins produce singlet oxygen upon their exposure to UV (365-nm) light. Singlet oxygen in turn activates them to mutagens and DNA binding species. Aflatoxin metabo...more Number of Targets: 1 |
| T3D3671 | Aflatoxin G2 7241-98-7 | C18H18ClNO4 347.793 g/mol |  |
| Aflatoxins produce singlet oxygen upon their exposure to UV (365-nm) light. Singlet oxygen in turn activates them to mutagens and DNA binding species. Aflatoxin metabo...more Number of Targets: 1 |
| T3D3666 | Aflatoxin M1 6795-23-9 | C17H12O7 328.273 g/mol |  |
| Aflatoxins produce singlet oxygen upon their exposure to UV (365-nm) light. Singlet oxygen in turn activates them to mutagens and DNA binding species. Aflatoxin M1 is ...more Number of Targets: 2 |