Browsing Toxins By Category
Displaying toxin 576 - 600 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D4804 | 2,4,6-Tribromophenol 118-79-6 | C6H3Br3O 330.799 g/mol |  |
| Not Available Number of Targets: 3 |
| T3D0419 | 2,4,6-Trichlorobiphenyl 35693-92-6 | C12H7Cl3 257.543 g/mol |  |
| The mechanism of action varies with the specific PCB. Dioxin-like PCBs bind to the aryl hydrocarbon receptor, which disrupts cell function by altering the transcriptio...more Number of Targets: 7 |
| T3D2249 | 2,4,6-Trichlorodibenzofuran 58802-14-5 | C12H5Cl3O 271.527 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D0086 | 2,4,6-Trichlorophenol 88-06-2 | C6H3Cl3O 197.446 g/mol |  |
| 2,4,6-Trichlorophenol is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acety...more Number of Targets: 40 |
| T3D0082 | 2,4,6-Trinitrotoluene 118-96-7 | C7H5N3O6 227.131 g/mol |  |
| 2,4,6-Trinitrotoluene is a competitive inhibitor with respect to NADPH and a noncompetitive inhibitor with respect to L-arginine. It binds to the P450 reductase domain...more Number of Targets: 1 |
| T3D2436 | 2,4,7-Trichlorodibenzofuran 83704-42-1 | C12H5Cl3O 271.527 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2250 | 2,4,8-Trichlorodibenzofuran 54589-71-8 | C12H5Cl3O 271.527 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2437 | 2,4,9-Trichlorodibenzofuran 82911-59-9 | C12H5Cl3O 271.527 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D4878 | 2,4-Di-tert-butylphenol 96-76-4 | C14H20O 204.308 g/mol |  |
| Not Available Number of Targets: 9 |
| T3D1957 | 2,4-Dibromobiphenyl 53592-10-2 | C12H8Br2 312.000 g/mol |  |
| The exact mechanism of toxicty of PBBs varies depending on the specific congener. The predominant interaction is believed to involve the aryl hydrocarbon receptor (AhR...more Number of Targets: 1 |
| T3D0396 | 2,4-Dichlorobiphenyl 33284-50-3 | C12H8Cl2 223.098 g/mol |  |
| The mechanism of action varies with the specific PCB. Dioxin-like PCBs bind to the aryl hydrocarbon receptor, which disrupts cell function by altering the transcriptio...more Number of Targets: 7 |
| T3D2251 | 2,4-Dichlorodibenzofuran 24478-74-8 | C12H6Cl2O 237.081 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D0209 | 2,4-Dichlorophenol 120-83-2 | C6H4Cl2O 163.001 g/mol |  |
| Chlorophenols have moderately high lipophilicity. Absorption through the gastrointestinal tract is by simple diffusion and is expected to be both rapid and virtually c...more Number of Targets: 3 |
| T3D0248 | 2,4-Dichlorophenoxyacetic acid 94-75-7 | C8H6Cl2O3 221.037 g/mol |  |
| 2,4-Dichlorophenoxyacetic acid is a strong oxidant and is known to cause lipid peroxidation and the generation of free radicals that can modify lipids and proteins. It...more Number of Targets: 9 |
| T3D0802 | 2,4-Dichlorophenoxybutyric acid 94-82-6 | C10H10Cl2O3 249.091 g/mol |  |
| Some of the endocrine effects of 2,4-DB may be mediated by the 2,4-D mediated displacement of sex hormones from the sex hormone binding globulin or the 2,4-D mediated ...more Number of Targets: 9 |
| T3D0895 | 2,4-Dimethyl-1,3-dithiolane-2-carboxaldehyde O-(methylcarbamoyl)oxime 26419-73-8 | C8H14N2O2S2 234.339 g/mol |  |
| 2,4-Dimethyl-1,3-dithiolane-2-carboxaldehyde O-(methylcarbamoyl)oxime is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes ...more Number of Targets: 2 |
| T3D3447 | 2,4-Dimethylhexane 589-43-5 | C8H18 114.229 g/mol |  |
| Petroleum distillates are central nervous system depressants and cause pulmonary damage. (A600) Number of Targets: 0 |
| T3D3436 | 2,4-Dimethylpentane 108-08-7 | C7H16 100.202 g/mol |  |
| Petroleum distillates are central nervous system depressants and cause pulmonary damage. (A600) Number of Targets: 0 |
| T3D0087 | 2,4-Dinitrophenol 51-28-5 | C6H4N2O5 184.106 g/mol |  |
| Acute 2,4-dinitrophenol poisoning (from ingestion) involves uncoupling of oxidative phosphorylation, which presumably reduces body's reservoirs of high-energy phosphat...more Number of Targets: 1 |
| T3D0094 | 2,4-Dinitrotoluene 121-14-2 | C7H6N2O4 182.134 g/mol |  |
| 2,4-DNT may cause conversion of oxyhemoglobin to methemoglobin via oxidation of iron(II) to iron(III) by its metabolites. High levels of methemoglobin are removed by c...more Number of Targets: 11 |
| T3D1667 | 2,4-Toluene diisocyanate 584-84-9 | C9H6N2O2 174.156 g/mol |  |
| 2,4-Toluene diisocyanate is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of ac...more Number of Targets: 51 |
| T3D4669 | 2,4-Toluenediamine 95-80-7 | C7H10N2 122.168 g/mol |  |
| Not Available Number of Targets: 2 |
| T3D1961 | 2,5-Dibromobiphenyl 57422-77-2 | C12H8Br2 312.000 g/mol |  |
| The exact mechanism of toxicty of PBBs varies depending on the specific congener. The predominant interaction is believed to involve the aryl hydrocarbon receptor (AhR...more Number of Targets: 1 |
| T3D0398 | 2,5-Dichlorobiphenyl 34883-39-1 | C12H8Cl2 223.098 g/mol |  |
| The mechanism of action varies with the specific PCB. Dioxin-like PCBs bind to the aryl hydrocarbon receptor, which disrupts cell function by altering the transcriptio...more Number of Targets: 7 |
| T3D3982 | 2,5-Dimethylfuran 625-86-5 | C6H8O 96.127 g/mol |  |
| 2,5-Dimethylfuran plays a role in the mechanism for the neurotoxicity of hexane in humans. Together with hexane-2,5-dione and 4,5-dihydroxy-2-hexanone, it is one of th...more Number of Targets: 0 |