Browsing Toxins By Category
Displaying toxin 2951 - 2975 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D1880 | Potassium pyroantimonate 10090-54-7 | H2K2O7Sb2 435.730 g/mol |  |
| The inhalation data suggests that the myocardium is a target of antimony toxicity. It is possible that antimony affects circulating glucose by interfering with enzymes...more Number of Targets: 20 |
| T3D0764 | Potassium silver cyanide 506-61-6 | C2ArKN2 131.081 g/mol |  |
| Cyanide is an inhibitor of cytochrome c oxidase in the fourth complex of the electron transport chain (found in the membrane of the mitochondria of eukaryotic cells). ...more Number of Targets: 51 |
| T3D1425 | Potassium tetraperoxochromate(V) 12331-76-9 | CrK3O8 297.286 g/mol |  |
| Chromium has been shown to induce carcinogenesis by overstimulating cellular regulatory pathways and increasing peroxide levels by activating certain mitogen-activated...more Number of Targets: 4 |
| T3D0718 | Potassium zinc chromate hydroxide 11103-86-9 | Cr2HKO9Zn2 418.911 g/mol |  |
| Anaemia results from the excessive absorption of zinc suppressing copper and iron absorption, most likely through competitive binding of intestinal mucosal cells. Unba...more Number of Targets: 6 |
| T3D0217 | Potassium-40 13966-00-2 | K 39.964 g/mol |  |
| The ionizing radiation produced by potassium causes cellular damage that includes DNA breakage, accurate or inaccurate repair, apoptosis, gene mutations, chromosomal c...more Number of Targets: 1 |
| T3D4526 | Prallethrin 23031-36-9 | C19H24O3 300.392 g/mol |  |
| Not Available Number of Targets: 21 |
| T3D2783 | Pramipexole 104632-26-0 | C10H17N3S 211.327 g/mol |  |
| The precise mechanism of action of Pramipexole as a treatment for Parkinson's disease is unknown, although it is believed to be related to its ability to stimulate dop...more Number of Targets: 14 |
| T3D3054 | Prazepam 2955-38-6 | C19H17ClN2O 324.804 g/mol |  |
| Prazepam is believed to stimulate GABA receptors in the ascending reticular activating system. Since GABA is inhibitory, receptor stimulation increases inhibition and ...more Number of Targets: 18 |
| T3D4710 | Prednisone 53-03-2 | C21H26O5 358.428 g/mol |  |
| Prednisone is a glucocorticoid receptor agonist. It is first metabolized in the liver to its active form, prednisolone. Prednisolone crosses cell membranes and binds w...more Number of Targets: 4 |
| T3D3902 | Primisulfuron-methyl 86209-51-0 | C15H12F4N4O7S 468.337 g/mol |  |
| Not Available Number of Targets: 7 |
| T3D3592 | Proamanullin 54532-46-6 | C39H54N10O11S 870.971 g/mol |  |
| The major toxic mechanism of amatoxins is the inhibition of RNA polymerase II, a vital enzyme in the synthesis of messenger RNA (mRNA), microRNA, and small nuclear RNA...more Number of Targets: 14 |
| T3D2869 | Procaine 59-46-1 | C13H20N2O2 236.310 g/mol |  |
| Procaine acts mainly by inhibiting sodium influx through voltage gated sodium channels in the neuronal cell membrane of peripheral nerves. When the influx of sodium is...more Number of Targets: 11 |
| T3D4711 | Procarbazine 671-16-9 | C12H19N3O 221.299 g/mol |  |
| The precise mode of cytotoxic action of procarbazine has not been clearly defined. There is evidence that the drug may act by inhibition of protein, RNA and DNA synthe...more Number of Targets: 1 |
| T3D3903 | Prochloraz 67747-09-5 | C15H16Cl3N3O2 376.665 g/mol |  |
| Prochloraz acts in vitro as a an aromatase inhibitor, aryl hydrocarbon receptor agonist, androgen receptor antagonist, and estrogen receptor antagonist. (A15203) Number of Targets: 36 |
| T3D2789 | Prochlorperazine 58-38-8 | C20H24ClN3S 373.943 g/mol |  |
| The mechanism of action of prochlorperazine has not been fully determined, but may be primarily related to its antidopaminergic effects. Prochlorperazine blocks the D2...more Number of Targets: 9 |
| T3D2773 | Procyclidine 77-37-2 | C19H29NO 287.440 g/mol |  |
| The mechanism of action is unknown. It is thought that Procyclidine acts by blocking central cholinergic receptors, and thus balancing cholinergic and dopaminergic act...more Number of Targets: 4 |
| T3D4527 | Prodiamine 29091-21-2 | C13H17F3N4O4 350.294 g/mol |  |
| Not Available Number of Targets: 18 |
| T3D4528 | Profenofos 41198-08-7 | C11H15BrClO3PS 373.631 g/mol |  |
| Profenofos is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholineste...more Number of Targets: 18 |
| T3D2908 | Progabide 62666-20-0 | C17H16ClFN2O2 334.773 g/mol |  |
| Progabide binds to both GABAA and GABAB receptors located on the terminals of primary afferent fibers. Binding to GABAA results in an increased affinity of the GABA re...more Number of Targets: 2 |
| T3D3904 | Prohexadione-calcium 127277-53-6 | C20H22CaO10 462.461 g/mol |  |
| Not Available Number of Targets: 3 |
| T3D0998 | Promacyl 34264-24-9 | C16H23NO3 277.359 g/mol |  |
| Promacyl is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoylation of the active sites o...more Number of Targets: 2 |
| T3D2565 | Promazine 58-40-2 | C17H20N2S 284.419 g/mol |  |
| Promazine is an antagonist at types 1, 2, and 4 dopamine receptors, 5-HT receptor types 2A and 2C, muscarinic receptors 1 through 5, alpha(1)-receptors, and histamine ...more Number of Targets: 16 |
| T3D0999 | Promecarb 2631-37-0 | C12H17NO2 207.269 g/mol |  |
| Promecarb is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoylation of the active sites ...more Number of Targets: 2 |
| T3D4560 | Promethazine 60-87-7 | C17H20N2S 284.419 g/mol |  |
| Like other H1-antagonists, promethazine competes with free histamine for binding at H1-receptor sites in the GI tract, uterus, large blood vessels, and bronchial muscl...more Number of Targets: 13 |
| T3D3905 | Prometon 1610-18-0 | C10H19N5O 225.291 g/mol |  |
| Not Available Number of Targets: 9 |