Browsing Toxins By Category
Displaying toxin 2901 - 2925 of 3678 in total
T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
---|---|---|---|---|---|
T3D4523 | Picloram 1918-02-1 | C6H3Cl3N2O2 241.459 g/mol |
| Not Available Number of Targets: 2 | |
T3D2979 | Pilocarpine 54-71-7 | C11H16N2O2 208.257 g/mol |
| Pilocarpine is a cholinergic parasympathomimetic agent. It increase secretion by the exocrine glands, and produces contraction of the iris sphincter muscle and ciliary...more Number of Targets: 4 | |
T3D2984 | Pimozide 2062-78-4 | C28H29F2N3O 461.546 g/mol |
| The ability of pimozide to suppress motor and phonic tics in Tourette's Disorder is thought to be primarily a function of its dopaminergic blocking activity. Pimozide ...more Number of Targets: 18 | |
T3D0822 | Pimpinellin 131-12-4 | C13H10O5 246.216 g/mol |
| Pimpinellin acts as antagonist of proteins with GABA receptor activity (L579). The mechanism of action many furocoumarins is based on their ability to form photoadduct...more Number of Targets: 3 | |
T3D4586 | Pinazepam 52463-83-9 | C18H13ClN2O 308.762 g/mol |
| Benzodiazepines bind nonspecifically to benzodiazepine receptors BNZ1, which mediates sleep, and BNZ2, which affects affects muscle relaxation, anticonvulsant activity...more Number of Targets: 18 | |
T3D4981 | Pioglitazone 111025-46-8 | C19H20N2O3S 356.439 g/mol |
| Pioglitazone acts as an agonist at peroxisome proliferator activated receptors (PPAR) in target tissues for insulin action such as adipose tissue, skeletal muscle, and...more Number of Targets: 3 | |
T3D4524 | Piperonyl butoxide 51-03-6 | C19H30O5 338.439 g/mol |
| Not Available Number of Targets: 19 | |
T3D0995 | Pirimicarb 23103-98-2 | C11H18N4O2 238.286 g/mol |
| Pirimicarb is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoylation of the active sites...more Number of Targets: 8 | |
T3D4525 | Pirimiphos-methyl 29232-93-7 | C11H20N3O3PS 305.334 g/mol |
| Pirimiphos-methyl is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcho...more Number of Targets: 18 | |
T3D1746 | Platinum(II) bromide 13455-12-4 | Br2Pt 354.892 g/mol |
| Bromine is a powerful oxidizing agent and is able to release oxygen free radicals from the water in mucous membranes. These free radicals are also potent oxidizers and...more Number of Targets: 6 | |
T3D1747 | Platinum(IV) bromide 68936-92-1 | Br4Pt 514.700 g/mol |
| Bromine is a powerful oxidizing agent and is able to release oxygen free radicals from the water in mucous membranes. These free radicals are also potent oxidizers and...more Number of Targets: 6 | |
T3D1329 | Plumbane 15875-18-0 | H4Pb 211.200 g/mol |
| Lead mimics other biologically important metals, such as zinc, calcium, and iron, competing as cofactors for many of their respective enzymatic reactions. For example,...more Number of Targets: 29 | |
T3D0126 | Plutonium 7440-07-5 | Pu 244.000 g/mol |
| The alpha radiation plutonium emits does not penetrate the skin but can irradiate internal organs when plutonium is inhaled or ingested. Particularly at risk are the s...more Number of Targets: 1 | |
T3D0124 | Plutonium-238 13981-16-3 | Pu 238.050 g/mol |
| The alpha radiation plutonium emits does not penetrate the skin but can irradiate internal organs when plutonium is inhaled or ingested. Particularly at risk are the s...more Number of Targets: 1 | |
T3D0121 | Plutonium-239 15117-48-3 | Pu 239.052 g/mol |
| The alpha radiation plutonium emits does not penetrate the skin but can irradiate internal organs when plutonium is inhaled or ingested. Particularly at risk are the s...more Number of Targets: 1 | |
T3D0140 | Plutonium-240 14119-33-6 | Pu 240.054 g/mol |
| The alpha radiation plutonium emits does not penetrate the skin but can irradiate internal organs when plutonium is inhaled or ingested. Particularly at risk are the s...more Number of Targets: 1 | |
T3D2620 | Pneumolysin Not Available | Not Available 52898.050 g/mol |
| Pneumolysin binds to cholesterol the undergoes oligomerization and membrane pore formation. Pneumolysin also activates the classical pathway of complement. Mutational ...more Number of Targets: 1 | |
T3D4617 | Podofilox 477-47-4 | C22H22O8 414.405 g/mol |
| Etoposide, a semisynthetic derivative of podofilox, induces DNA breakage through its inhibition of topoisomerase II. The drug is most active in the late S and early G2...more Number of Targets: 7 | |
T3D0122 | Polonium-210 13981-52-7 | Po 209.983 g/mol |
| The alpha radiation polonium emits does not penetrate the skin but can irradiate internal organs when polonium is inhaled or ingested. The ionizing radiation produced ...more Number of Targets: 1 | |
T3D3659 | Polyethylene terephthalate 25038-59-9 | C10H12O6 228.199 g/mol |
| Antimony is a catalyst that is often used as antimony trioxide or antimony triacetate in the production of PET. It remains in the material and can thus in principle mi...more Number of Targets: 21 | |
T3D3529 | Polymyxin B Sulfate 1405-20-5 | C56H98N16O13 1203.477 g/mol |
| Polymyxin B sulfate has a bactericidal action against almost all gram-negative bacilli except the Proteus group. Polymyxin B sulfate interacts with the lipopolysacchar...more Number of Targets: 0 | |
T3D4917 | Polypropylene glycol (m w 1,200-3,000) 25322-69-4 | C6H14O3 134.174 g/mol |
| Not Available Number of Targets: 1 | |
T3D3469 | Polyvinyl acetate 9003-20-7 | C6H12O2 116.158 g/mol |
| Polyvinyl acetate usually contains trace amounts of its precursor, vinyl acetate. One of the metabolites of vinyl acetate, acetaldehyde, is a known animal carcinogen. ...more Number of Targets: 1 | |
T3D2493 | Poneratoxin 137084-94-7 | Not Available 2757.330 g/mol |
| Poneratoxin affects voltage-dependent sodium ion channels and is known to block nicotinic synaptic transmission in the insect central nervous system. (L1019) Number of Targets: 14 | |
T3D4274 | Porphobilinogen 487-90-1 | C10H14N2O4 226.229 g/mol |
| Not Available Number of Targets: 1 |