Browsing Toxins By Category
Displaying toxin 2876 - 2900 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D4905 | Phenyl salicylate 118-55-8 | C13H10O3 214.217 g/mol |  |
| Not Available Number of Targets: 3 |
| T3D4805 | Phenylacetaldehyde 122-78-1 | C8H8O 120.149 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D4153 | Phenylacetic acid 103-82-2 | C8H8O2 136.148 g/mol |  |
| Uremic toxins such as phenylacetic acid are actively transported into the kidneys via organic ion transporters (especially OAT3). Increased levels of uremic toxins can...more Number of Targets: 5 |
| T3D1312 | Phenyldichloroarsine 696-28-6 | C6H5AsCl2 222.932 g/mol |  |
| Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co...more Number of Targets: 45 |
| T3D1681 | Phenylene-1,4-diisothiocyanate 4044-65-9 | C8H4N2S2 192.261 g/mol |  |
| Cyanide is an inhibitor of cytochrome c oxidase in the fourth complex of the electron transport chain (found in the membrane of the mitochondria of eukaryotic cells). ...more Number of Targets: 39 |
| T3D0344 | Phenylmercuric acetate 62-38-4 | C8H8HgO2 336.740 g/mol |  |
| High-affinity binding of the divalent mercuric ion to thiol or sulfhydryl groups of proteins is believed to be the major mechanism for the activity of mercury. Through...more Number of Targets: 98 |
| T3D1363 | Phenylmercuric borate 102-98-7 | C6H7BHgO3 338.520 g/mol |  |
| High-affinity binding of the divalent mercuric ion to thiol or sulfhydryl groups of proteins is believed to be the major mechanism for the activity of mercury. Through...more Number of Targets: 50 |
| T3D1354 | Phenylmercuric chloride 100-56-1 | C6H5ClHg 313.150 g/mol |  |
| High-affinity binding of the divalent mercuric ion to thiol or sulfhydryl groups of proteins is believed to be the major mechanism for the activity of mercury. Through...more Number of Targets: 51 |
| T3D1355 | Phenylmercuric nitrate 55-68-5 | C6H5HgNO3 339.700 g/mol |  |
| High-affinity binding of the divalent mercuric ion to thiol or sulfhydryl groups of proteins is believed to be the major mechanism for the activity of mercury. Through...more Number of Targets: 59 |
| T3D2728 | Phenytoin 57-41-0 | C15H12N2O2 252.268 g/mol |  |
| Phenytoin acts on sodium channels on the neuronal cell membrane, limiting the spread of seizure activity and reducing seizure propagation. By promoting sodium efflux f...more Number of Targets: 10 |
| T3D2489 | Philanthotoxin 77108-00-0 | C23H41N5O3 435.603 g/mol |  |
| Philanthotoxins block glutamate receptors, especially the calcium permeable AMPA receptor and kainate receptor. (L1016) Number of Targets: 9 |
| T3D2503 | Phoneutriatoxin Not Available | Not Available 12677.715 g/mol |  |
| Phoneutriatoxin acts as an antagonist at certain calcium channels. (T170) Number of Targets: 3 |
| T3D0225 | Phorate 298-02-2 | C7H17O2PS3 260.377 g/mol |  |
| Phorate is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholinesteras...more Number of Targets: 5 |
| T3D4069 | Phorbol 17673-25-5 | C20H28O6 364.433 g/mol |  |
| The term 'phorbol' is used to describe the family of naturally occurring compounds that can be referred to as tigliane diterpenes. Phorbol esters are the tetracyclic d...more Number of Targets: 0 |
| T3D3901 | Phosalone 2310-17-0 | C12H15ClNO4PS2 367.809 g/mol |  |
| Phosalone is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholinester...more Number of Targets: 21 |
| T3D4653 | Phosgene oxime 1794-86-1 | CHCl2NO 113.931 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D0259 | Phosphine 7803-51-2 | H3P 33.998 g/mol |  |
| Phosphine inhibits cytochrome c oxidase, preventing mitochondrial oxidative phosphorylation. This non-competitive inhibition prevents cellular respiration and leads to...more Number of Targets: 20 |
| T3D4896 | Phosphoric acid 7664-38-2 | H3O4P 97.995 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D1744 | Phosphorus pentabromide 7789-69-7 | Br5P 430.494 g/mol |  |
| Bromine is a powerful oxidizing agent and is able to release oxygen free radicals from the water in mucous membranes. These free radicals are also potent oxidizers and...more Number of Targets: 6 |
| T3D1745 | Phosphorus tribromide 7789-60-8 | Br3P 270.686 g/mol |  |
| Bromine is a powerful oxidizing agent and is able to release oxygen free radicals from the water in mucous membranes. These free radicals are also potent oxidizers and...more Number of Targets: 6 |
| T3D2501 | Phrixotoxin 880886-00-0 or 221872-97-5 | Not Available 3555.310 g/mol |  |
| Phrixotoxin blocks A-type potassium channels by altering the gating properties of these channels. (T170) Number of Targets: 2 |
| T3D1707 | Phthalonitrile 91-15-6 | C8H4N2 128.131 g/mol |  |
| Organic nitriles decompose into cyanide ions both in vivo and in vitro. Consequently the primary mechanism of toxicity for organic nitriles is their production of toxi...more Number of Targets: 39 |
| T3D4454 | Phytanic acid 14721-66-5 | C20H40O2 312.530 g/mol |  |
| Not Available Number of Targets: 4 |
| T3D2959 | Phytonadione 84-80-0 | C31H46O2 450.696 g/mol |  |
| Vitamin K is an essential cofactor for the gamma-carboxylase enzymes which catalyze the posttranslational gamma-carboxylation of glutamic acid residues in inactive hep...more Number of Targets: 2 |
| T3D0636 | Picene 213-46-7 | C22H14 278.347 g/mol |  |
| The ability of PAH's to bind to blood proteins such as albumin allows them to be transported throughout the body. Many PAH's induce the expression of cytochrome P450 e...more Number of Targets: 3 |