Browsing Toxins By Category
Displaying toxin 2851 - 2875 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D2471 | Phallacidin 26645-35-2 | Not Available 2570.930 g/mol |  |
| Phallotoxins bind actin, preventing its depolymerization and poisoning the cell. They bind specifically at the interface between F-actin subunits, locking adjacent sub...more Number of Targets: 6 |
| T3D2472 | Phallacin 53568-40-4 | C37H50N8O12S 830.904 g/mol |  |
| Phallotoxins bind actin, preventing its depolymerization and poisoning the cell. They bind specifically at the interface between F-actin subunits, locking adjacent sub...more Number of Targets: 6 |
| T3D2473 | Phallisacin 58286-46-7 | C37H50N8O14S 862.903 g/mol |  |
| Phallotoxins bind actin, preventing its depolymerization and poisoning the cell. They bind specifically at the interface between F-actin subunits, locking adjacent sub...more Number of Targets: 6 |
| T3D2470 | Phallisin 19774-69-7 | C35H48N8O12S 804.867 g/mol |  |
| Phallotoxins bind actin, preventing its depolymerization and poisoning the cell. They bind specifically at the interface between F-actin subunits, locking adjacent sub...more Number of Targets: 6 |
| T3D2467 | Phalloidin 17466-45-4 | Not Available 3301.700 g/mol |  |
| It binds actin, preventing its depolymerization and poisoning the cell. Phalloidin binds specifically at the interface between F-actin subunits, locking adjacent subun...more Number of Targets: 6 |
| T3D2469 | Phalloin 28227-92-1 | C35H48N8O10S 772.868 g/mol |  |
| Phallotoxins bind actin, preventing its depolymerization and poisoning the cell. They bind specifically at the interface between F-actin subunits, locking adjacent sub...more Number of Targets: 6 |
| T3D0846 | Phellopterin 2543-94-4 | C17H16O5 300.306 g/mol |  |
| The mechanism of action many furocoumarins is based on their ability to form photoadducts with DNA and other cellular components such as RNA, proteins, and several pro...more Number of Targets: 4 |
| T3D2990 | Phenacemide 63-98-9 | C9H10N2O2 178.188 g/mol |  |
| Phenacemide binds to and blocks neuronal sodium channels or voltage sensitive calcium channels. This blocks or suppresses neuronal depolarization and hypersynchronizat...more Number of Targets: 1 |
| T3D4707 | Phenacetin 62-44-2 | C10H13NO2 179.216 g/mol |  |
| Phenacetin's analgesic effects are due to its actions on the sensory tracts of the spinal cord. In addition, phenacetin has a depressant action on the heart, where it ...more Number of Targets: 1 |
| T3D1801 | Phenacyl bromide 70-11-1 | C8H7BrO 199.045 g/mol |  |
| Organobromide compounds such as phenacyl bromide are strong alkylating agents. Consequently they can readily modify free thiols (cysteines) and methionine residues of...more Number of Targets: 5 |
| T3D0246 | Phenanthrene 85-01-8 | C14H10 178.229 g/mol |  |
| The ability of PAH's to bind to blood proteins such as albumin allows them to be transported throughout the body. Many PAH's induce the expression of cytochrome P450 e...more Number of Targets: 6 |
| T3D1321 | Phenarsazine oxide 58-36-6 | C24H16As2O3 502.225 g/mol |  |
| Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co...more Number of Targets: 44 |
| T3D2889 | Phenelzine 51-71-8 | C8H12N2 136.194 g/mol |  |
| Although the exact mechanism of action has not been determined, it appears that the irreversible, nonselective inhibition of MAO by phenelzine relieves depressive symp...more Number of Targets: 11 |
| T3D3060 | Phenindamine 82-88-2 | C19H19N 261.361 g/mol |  |
| Antihistamines such as phenindamine appear to compete with histamine for histamine H1- receptor sites on effector cells. The antihistamines antagonize those pharmacolo...more Number of Targets: 1 |
| T3D3107 | Phenindione 83-12-5 | C15H10O2 222.239 g/mol |  |
| Phenindione inhibits vitamin K reductase, resulting in depletion of the reduced form of vitamin K (vitamin KH2). As vitamin K is a cofactor for the carboxylation of gl...more Number of Targets: 1 |
| T3D0994 | Phenmedipham 13684-63-4 | C16H16N2O4 300.309 g/mol |  |
| Phenmedipham is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoylation of the active sit...more Number of Targets: 5 |
| T3D2904 | Phenmetrazine 134-49-6 | C11H15NO 177.243 g/mol |  |
| Phenmetrazine is thought to block the reuptake of norepinephrine and dopamine into the presynaptic neuron leading to an increase in the release of these monoamines int...more Number of Targets: 3 |
| T3D3006 | Phenobarbital 50-06-6 | C12H12N2O3 232.235 g/mol |  |
| Phenobarbital acts on GABAA receptors, increasing synaptic inhibition. This has the effect of elevating seizure threshold and reducing the spread of seizure activity f...more Number of Targets: 9 |
| T3D0182 | Phenol 108-95-2 | C6H6O 94.111 g/mol |  |
| Phenol is irritating and corrosive at high concentrations. Phenol impairs the stratum corneum and produces coagulation necrosis by denaturing and precipitating protein...more Number of Targets: 13 |
| T3D4708 | Phenolphthalein 77-09-8 | C20H14O4 318.323 g/mol |  |
| Not Available Number of Targets: 12 |
| T3D1026 | Phenothrin 26002-80-2 | C23H26O3 350.451 g/mol |  |
| Both type I and type II pyrethroids exert their effect by prolonging the open phase of the sodium channel gates when a nerve cell is excited. They appear to bind to th...more Number of Targets: 21 |
| T3D3105 | Phenprocoumon 435-97-2 | C18H16O3 280.318 g/mol |  |
| Phenprocoumon inhibits vitamin K reductase, resulting in depletion of the reduced form of vitamin K (vitamin KH2). As vitamin K is a cofactor for the carboxylation of ...more Number of Targets: 3 |
| T3D2709 | Phentermine 122-09-8 | C10H15N 149.233 g/mol |  |
| Phentermine is an amphetamine that stimulates neurons to release or maintain high levels of a particular group of neurotransmitters known as catecholamines; these incl...more Number of Targets: 6 |
| T3D1659 | Phenyl isocyanate 103-71-9 | C7H5NO 119.121 g/mol |  |
| Cyanide is an inhibitor of cytochrome c oxidase in the fourth complex of the electron transport chain (found in the membrane of the mitochondria of eukaryotic cells). ...more Number of Targets: 39 |
| T3D0781 | Phenyl isothiocyanate 103-72-0 | C7H5NS 135.186 g/mol |  |
| Cyanide is an inhibitor of cytochrome c oxidase in the fourth complex of the electron transport chain (found in the membrane of the mitochondria of eukaryotic cells). ...more Number of Targets: 39 |