Search Results for compounds

Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched toxicity: … No significant lethality was observed when itraconazole was administered orally to mice and rats at dosage levels of 320 mg/kg or to dogs at 200 mg/kg. …
Matched description: … Itraconazole is only found in individuals that have used or taken this drug. It is one of the ... triazole antifungal agents that inhibits cytochrome P-450-dependent enzymes resulting in impairment of ... enzyme necessary to convert lanosterol to ergosterol. As ergosterol is an essential component of the …

Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched description: … only of n carbon atoms and m hydrogen atoms where m=2*n + 2 ... Pentadecane belongs to the family of Acyclic Alkanes. These are acyclic hydrocarbons consisting …

Matched symptoms: … , fever, headache, weakness, dryness of the nose and throat, chest pain, and coughing. Ingestion of cadmium causes vomiting and diarrhea. (L6) ... Acute inhalation of cadmium fumes results in metal fume fever, which is characterized by chills …
Matched treatment: … Cadmium poisoning is treated by removal from exposure and supportive care. If ingested, induced vomiting or gastric lavage may be performed. (L139) …
Matched description: … Cadmium sulfide is a sulfide of cadmium that occurs naturally as the minerals greenockite and ... hawleyite and is also produced by sulfate reducing bacteria. It is used mainly as a semiconductor and ... pigment. Cadmium is a transition metal and chemical element with the symbol Cd and atomic number 48. It …

Matched symptoms: … Inhalating aluminum dust causes coughing and abnormal chest X-rays. A small percentage of people ... are allergic to aluminium and experience contact dermatitis, digestive disorders, vomiting or other ... symptoms upon contact or ingestion of products containing aluminium. (L739, L740) …
Matched carcinogenicity: … -containing antiperspirants and increased risk of breast cancer has been proposed (A235), but studies have not been able to establish a clear link (A15468). ... did not implicate aluminum itself as a human carcinogen. (L135) A link between use of aluminum ... Not listed by IARC. IARC classified aluminum production as carcinogenic to humans (Group 1), but …
Matched treatment: … EYES: irrigate opened eyes for several minutes under running water. INGESTION: do not induce ... water for at least 15 minutes, followed by thorough washing with soap and water. If necessary, the ... person should shower and change contaminated clothing and shoes, and then must seek medical attention …
Matched description: … Sodium aluminium hydride is a hydride of sodium and aluminum. It is a reducing agent and is used ... for hydrogen storage in hydrogen tanks. Aluminum is the most abundant metal in the earth's crust and ... is always found combined with other elements such as oxygen, silicon, and fluorine. (L739, L740, L778) …

Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched description: … has a low aqueous solubility, not considered particulatly volatile and, based on its chemical ... properties, is not expected to leach to groundwater. It is moderately toxic to mammals and not expected to ... Pyridaben is an insecticide and acaricide that is effective against thrips, mites, aphids and …

Matched symptoms: … Avermectins cause irritation of skin and eyes, central nervous system depression (incoordination ... , tremors, lethargy, excitation, pupil dilation, coma), vomiting, convulsions and/or tremors, and respiratory failure at high doses. (L1826) …
Matched carcinogenicity: … Not listed by IARC. …
Matched description: … broad range of nematodes and arthropod parasites of domestic animals at dose rates of 300 microgram ... The avermectins are a series of macrocyclic lactone derivatives with potent anthelmintic properties ... . A commonly used therapy in recent times has been based on oral or parenteral administration of …

Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched description: … antagonist that crosses the blood-brain barrier and is used in the treatment of drug-induced ... extrapyramidal disorders and in parkinsonism. The mechanism of action is unknown. It is thought that ... Procyclidine acts by blocking central cholinergic receptors, and thus balancing cholinergic and dopaminergic …

Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched description: … the release of hypothalamic and hypophyseal hormones and is believed to depress the reticular ... drug, used in hospitalized patients in the management of chronic schizophrenic psychoses.A yellow ... , powdered, phenothiazine antipsychotic agent used in the treatment of acute or chronic schizophrenia …

Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched description: … . Salbutamol is formulated as a racemic mixture of the R- and S-isomers. The R-isomer has 150 times ... Salbutamol is a short-acting, selective beta2-adrenergic receptor agonist used in the treatment of ... asthma and COPD. It is 29 times more selective for beta2 receptors than beta1 receptors giving it …

Matched symptoms: … Bromine vapour causes irritation and direct damage to the mucous membranes. Symptoms include ... lacrimation, rhinorrhoea, eye irritation with mucous secretions from the oropharyngeal and upper airways ... , coughing, dyspnoea, choking, wheezing, epistaxis, and headache. The bromide ion is a central nervous …
Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched treatment: … EYES: irrigate opened eyes for several minutes under running water. INGESTION: do not induce ... cold running water for at least 15 minutes, followed by thorough washing with soap and water. If ... necessary, the person should shower and change contaminated clothing and shoes, and then must seek …
Matched description: … Potassium bromide is a chemical compound of potassium and bromine. It was widely used as an ... symbol Br and atomic number 35. Diatomic bromine does not occur naturally, but bromine salts can be found in crustal rock. (L625, L627) ... anticonvulsant and a sedative in the late 19th and early 20th centuries, but today is only used in …

Matched symptoms: … Bromine vapour causes irritation and direct damage to the mucous membranes. Symptoms include ... lacrimation, rhinorrhoea, eye irritation with mucous secretions from the oropharyngeal and upper airways ... , coughing, dyspnoea, choking, wheezing, epistaxis, and headache. The bromide ion is a central nervous …
Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched treatment: … EYES: irrigate opened eyes for several minutes under running water. INGESTION: do not induce ... cold running water for at least 15 minutes, followed by thorough washing with soap and water. If ... necessary, the person should shower and change contaminated clothing and shoes, and then must seek …
Matched description: … dibrompropamidine isethionate, it is also used in eyedrops and ointment for the treatment of infections ... . Bromine is a halogen element with the symbol Br and atomic number 35. Diatomic bromine does not occur ... Dibrompropamidine is an organobromide compound. It is an antiseptic and disinfectant. As …

Matched symptoms: … 4-Aminophenol may cause contact dermatitis. Signs and symptoms of methemoglobinemia may include ... , dizziness and loss of consciousness. Severe methemoglobinemia can result in dysrhythmias, seizures, coma, and death. (T21, L1613) ... shortness of breath, cyanosis, mental status changes, headache, fatigue, exercise intolerance …
Matched carcinogenicity: … Not listed by IARC. …
Matched treatment: … Methemoglobinemia can be treated with supplemental oxygen and methylene blue 1% solution …
Matched description: … synthesis of dyes and can thus be found in numerous cosmetics products, particularly hair dyes. 4 ... -aminophenol is considered a minor nephrotoxic metabolite of phenacetin and acetaminophen (paracetamol ... 4-Aminophenol is an amphoteric molecule and a reducing agent. Aminophenols are intermediates in the …

Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched treatment: … first importance. Restoration of blood pressure and normalization of heart rate may be accomplished by ... bound; therefore, dialysis may not be of benefit. (L1712) ... Should overdosage of Terazosin lead to hypotension, support of the cardiovascular system is of …
Matched description: … (BPH). It also acts to lower blood pressure, so it is a drug of choice for men with hypertension and ... prostate enlargement. It works by blocking the action of adrenaline on smooth muscle of the bladder and the blood vessel walls. ... Terazosin is a selective alpha 1 antagonist used for treatment of symptoms of prostate enlargement …

Matched symptoms: … Symptoms of overdose include somnolence, confusion, coma, and diminished reflexes. Respiration, pulse and blood pressure should be monitored. …
Matched carcinogenicity: … 3, not classifiable as to its carcinogenicity to humans. (L135) …
Matched treatment: … a general rule, medical observation and supportive care are the mainstay of treatment of ... with activated charcoal is not beneficial in pure benzodiazepine overdose as the risk of adverse ... General supportive measures should be employed, along with intravenous fluids, and an adequate …
Matched description: … that is used in the treatment of anxiety disorders. It is a schedule IV drug in the U.S. Prazepam is ... inhibitory, receptor stimulation increases inhibition and blocks both cortical and limbic arousal ... following stimulation of the brain stem reticular formation. …
Matched compound_type: … Hypnotic and Sedative …

Matched symptoms: … irritation. Short-term oral exposure to high concentrations of selenium may cause nausea, vomiting, and ... exposure to either of these air-borne forms can cause respiratory irritation, bronchial spasms, and coughing. (L619, L308) ... Inorganic or organic tin compounds placed on the skin or in the eyes can produce skin and eye …
Matched carcinogenicity: … 3, not classifiable as to its carcinogenicity to humans. (L135) …
Matched treatment: … EYES: irrigate opened eyes for several minutes under running water. INGESTION: do not induce ... water for at least 15 minutes, followed by thorough washing with soap and water. If necessary, the ... person should shower and change contaminated clothing and shoes, and then must seek medical attention …
Matched description: … Tin selenide is a chemical compound of tin and selenium. Tin is a chemical element with the symbol ... Sn and atomic number 50. It is a natural component of the earth's crust and is obtained chiefly from ... , forming the active center of the enzymes glutathione peroxidase, thioredoxin reductase, and three known deiodinase enzymes. (L620, L307, L309) …

Matched symptoms: … Breathing high levels of copper can cause irritation of the nose and throat. Ingesting high levels ... of copper can cause nausea, vomiting, diarrhea, headache, dizziness, and respiratory difficulty. (L278, L279) …
Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched treatment: … EYES: irrigate opened eyes for several minutes under running water. INGESTION: do not induce ... water for at least 15 minutes, followed by thorough washing with soap and water. If necessary, the ... person should shower and change contaminated clothing and shoes, and then must seek medical attention …
Matched description: … functioning of more than 30 enzymes. It occurs naturally throughout the environment in rocks, soil, water, and air. (L277, L278, L292) ... Copper(I) chloride is a chloride of copper that occurs naturally as the rare mineral nantokite. The ... main use of copper(I) chloride is as a precursor to the fungicide copper oxychloride. It is also …

Matched symptoms: … Symptoms of overdose include drowsiness, sedation, tachycardia, hypotension, and extrapyramidal symptoms. …
Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched treatment: … In case of acute overdosage, establish and maintain an airway and ensure adequate oxygenation and ... ventilation. Gastric lavage (after intubation, if patient is unconscious) and administration of ... , seizures, or dystonic reaction of the head and neck following overdose may create a risk of aspiration with …
Matched description: … antipsychotics) is also used to treat some forms of bipolar disorder, psychotic depression and Tourette syndrome ... antipsychotics) is also used to treat some forms of bipolar disorder, psychotic depression and Tourette ... symptomatic treatment of irritability in autistic children and adolescents. Risperidone is now the most …

Matched symptoms: … Symptions of chronic lead poisoning include reduced cognitive abilities, nausea, abdominal pain ... , headache and, in extreme cases, seizures, comas, and death. There are also associated gastrointestinal …
Matched description: … Lead sulfide is a sulfide of lead that occurs naturally as the mineral galena. It is used as a ... semiconductor and infrared detector. Lead is a heavy metal and stable element with the symbol Pb and the ... atomic number 82, existing in metallic, organic, and inorganic forms. It is mainly found in nature …

Matched symptoms: … Symptoms of overdose include difficulty in breathing (severe), dizziness (severe), drowsiness ... (severe), muscle trembling, jerking, stiffness, or uncontrolled movements (severe), small pupils, unusual excitement, and unusual tiredness or weakness (severe). …
Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched description: … the release of hypothalamic and hypophyseal hormones and is believed to depress the reticular ... antipsychotic drug of the thioxanthene (tricyclic) class. Chlorprothixene exerts strong blocking ... effects by blocking the 5-HT2 D1, D2, D3, histamine H1, muscarinic and alpha1 adrenergic receptors …

Matched symptoms: … Skin contact with palladium may cause contact dermatitis, erythema, and oedema. (L798) …
Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched treatment: … EYES: irrigate opened eyes for several minutes under running water. INGESTION: do not induce ... water for at least 15 minutes, followed by thorough washing with soap and water. If necessary, the ... person should shower and change contaminated clothing and shoes, and then must seek medical attention …
Matched description: … symbol Pd and an atomic number of 46. It is found as a free metal alloyed with gold and other platinum ... Palladium(II) oxide is an oxide of palladium. Palladium is a chemical element with the chemical ... group metals and in the rare minerals cooperite and polarite. (L794) …

Matched symptoms: … Skin contact with palladium may cause contact dermatitis, erythema, and oedema. (L798) …
Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched treatment: … EYES: irrigate opened eyes for several minutes under running water. INGESTION: do not induce ... water for at least 15 minutes, followed by thorough washing with soap and water. If necessary, the ... person should shower and change contaminated clothing and shoes, and then must seek medical attention …
Matched description: … element with the chemical symbol Pd and an atomic number of 46. It is found as a free metal alloyed ... Tetraammine palladium(II) chloride is a coordination complex of palladium. Palladium is a chemical ... with gold and other platinum group metals and in the rare minerals cooperite and polarite. (L794) …

Matched symptoms: … Bromine vapour causes irritation and direct damage to the mucous membranes. Symptoms include ... lacrimation, rhinorrhoea, eye irritation with mucous secretions from the oropharyngeal and upper airways ... , coughing, dyspnoea, choking, wheezing, epistaxis, and headache. The bromide ion is a central nervous …
Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched treatment: … EYES: irrigate opened eyes for several minutes under running water. INGESTION: do not induce ... cold running water for at least 15 minutes, followed by thorough washing with soap and water. If ... necessary, the person should shower and change contaminated clothing and shoes, and then must seek …
Matched description: … Platinum(II) bromide is a chemical compound of platinum and bromine. It is a common precursor to ... other platinum-bromide compounds. Bromine is a halogen element with the symbol Br and atomic number 35 ... . Diatomic bromine does not occur naturally, but bromine salts can be found in crustal rock. Like …

Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched description: … O-Desmethylangolensin (ODMA) is a metabolite of the soy isoflavone daidzein by intestinal bacteria ... in approximately 80-90% of persons. Studies suggest beneficial health effects associated with ... daidzein-metabolizing phenotypes, and there is some small association between ODMA production and some …

Matched symptoms: … Scorpion stings cause tingling or burning at the site of the sting. In more severe cases, symptoms ... may include spasm in the throat, feeling of thick tongue, restlessness, muscular fibrillation ... , abdominal cramps, convulsions, incontinence, hypertension, hypotension, oliguria, cardiac arrhythmias, pulmonary edema, and respiratory failure. (T156) …
Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched description: … development of new methods for the treatment and diagnosis of several types of cancer. (L1043) …

Matched symptoms: … In severe overdosage, particularly by the intravenous route, apnea, circulatory collapse, cardiac arrest, and death may occur. …
Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched treatment: … provision of a patent airway and institution of assisted or controlled ventilation. If a non-tolerant ... Primary attention should be given to the reestablishment of adequate respiratory exchange through ... person, takes a large dose of methadone, effective opioid antagonists are available to counteract …
Matched description: … mu-opioid agonist. It has actions and uses similar to those of morphine. It also has a depressant ... action on the cough center and may be given to control intractable cough associated with terminal ... lung cancer. Methadone is also used as part of the treatment of dependence on opioid drugs, although …