Search Results for compounds

Matched symptoms: … Exposure to high doses of ionizing radiation results in acute radiation syndrome, which can cause ... , fatigue, weakness, fever, birth defects, illness, infection, and death. (L1837, L1852) …
Matched treatment: … Treatment reversing the effects of irradiation is currently not possible. Anaesthetics and ... antiemetics are administered to counter the symptoms of exposure, as well as antibiotics for countering …
Matched description: … Plutonium is an element with the symbol Pu and atomic number 94. It is a rare transuranic ... radioactive element that normally exhibits six allotropes and four oxidation states. It is also a radioactive ... poison that accumulates in bone marrow. Plutonium-240 has a high rate of spontaneous fission …
Matched synonyms: … Plutonium, isotope of mass 240 …

Matched symptoms: … Signs of overdose include motor unrest, muscular twitching and rigidity, tremor, ataxia ... arrhythmias, impaired cardiac conduction, respiratory depression, and disturbances of consciousness up to deep coma. …
Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched description: … , possesses some anticholinergic activity, and does not affect monoamine oxidase activity. It differs from ... TCAs in that it does not appear to block serotonin reuptake. Maprotiline may be used to treat ... depressive affective disorders, including dysthymic disorder (depressive neurosis) and major depressive …

Matched symptoms: … Side effects include dry mouth, anorexia, insomnia, constipation and headache. …
Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched treatment: … and supportive measures should be instituted. Cautious use of p-blockers may be indicated to control elevated blood pressure or tachycardia. (L1712) ... Treatment should consist of general measures employed in the management of overdosage: an airway ... should be established as needed; cardiac and vital sign monitoring is recommended; general symptomatic …
Matched description: … from Canadian and U.S. markets due to concerns that the drug increases the risk of heart attack and stroke in patients with a history of heart disease. ... Sibutramine (trade name Meridia in the USA, Reductil in Europe and other countries), usually as ... sibutramide hydrochloride monohydrate, is an orally administered agent for the treatment of obesity. It …

Matched symptoms: … , nausea and vomiting, skin rash, swelling of the feet or lower legs, unusual tiredness or weakness, and yellow eyes or skin. (L1536) ... Side effects of the potential hepatotoxicity of Ketoconazole include abdominal pain or tenderness ... , clay-colored stools, dark urine, decreased appetite, fever, headache, itching, loss of appetite …
Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched treatment: … In the event of accidental overdosage, supportive measures, including gastric lavage with sodium bicarbonate, should be employed. (L1712) …
Matched description: … conversion of lanosterol to ergosterol. This results in inhibition of ergosterol synthesis and ... , inhibition of purine uptake, and impairment of triglyceride and/or phospholipid biosynthesis ... . Ketoconazole can also inhibit the synthesis of thromboxane and sterols such as aldosterone, cortisol, and testosterone. …

Matched symptoms: … Breathing modest amounts of bromomethane may lead to the development of a headache, nausea and ... , skin, and mucous membranes of the upper respiratory tract. Dermal exposure to bromomethane can ... weakness after several hours. Breathing high concentrations of bromomethane may cause pulmonary edema …
Matched carcinogenicity: … 3, not classifiable as to its carcinogenicity to humans. (L135) …
Matched treatment: … EYES: irrigate opened eyes for several minutes under running water. INGESTION: do not induce ... cold running water for at least 15 minutes, followed by thorough washing with soap and water. If ... necessary, the person should shower and change contaminated clothing and shoes, and then must seek …
Matched description: … cause of death is not certain, but is probably due to neurological and lung injury. ... a fumigant in soil to control fungi, nematodes, and weeds; in space fumigation of food commodities ... the fumigated substances, and its rapid dissipation following application. Trace amounts of methyl …

Matched symptoms: … Staphylococcus aureus is the most common cause of staph infections. It can also cause a range of ... , carbuncles, scalded skin syndrome, and abscesses, to life-threatening diseases such as pneumonia ... , meningitis, osteomyelitis, endocarditis, Toxic shock syndrome (TSS), and septicemia. (L1734, L1773) …
Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched treatment: … of damage to the kidneys. The duration of treatment depends on the site of infection and on severity. (L1773) ... The treatment of choice for S. aureus infection is penicillin, but in most countries, penicillin ... -resistance is extremely common and first-line therapy is most commonly a penicillinase-resistant …
Matched description: … Leukocidin F is a cytotoxin produced by Staphylococcus aureus. The presence of leukocidins is ... associated with increased virulence of certain strains (isolates) of Staphylococcus aureus. (L1779) …

Matched symptoms: … Symptoms of diphenyl poisoning include headache, fatigue, abdominal pain with nausea or diarrhea and various symptoms, vomiting and bronchitis (T48). …
Matched carcinogenicity: … No indication of carcinogenicity (not listed by IARC). (L135) …
Matched treatment: … can be performed soon after ingestion. In case of inhalation exposure, move patient to fresh air and ... . Treat bronchospasm with inhaled beta2 agonist and oral or parenteral corticosteroids. In case of ... Consider gastric lavage, after ingestion of a potentially life-threatening amount of poison if it …
Matched description: … belongs to the family of Biphenyls and Derivatives. These are organic compounds containing to benzene rings linked together by a C-C bond. ... as food preservative and flavouring agent. Biphenyl is detected in bilberry, wine grape, carrot ... , olive, buckwheat and tamarind. Generally, the fruit packaging is impregnated with biphenyl, which …

Matched symptoms: … The gastrointestinal effects can consist of nausea and vomiting, excess salivation, abdominal pain ... , diarrhea, and colic. Cardiac reactions consist of irregular heart rate, and extremities may become ... pale and cold due to poor or irregular circulation. Reactions to poisonings from this plant can also …
Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched treatment: … Oleandrin poisoning is treated by induced vomiting, gastric lavage, and/or administration of …
Matched description: … Oleandrin is a plant toxin found in Oleander (Nerium oleander). It causes both gastrointestinal and cardiac effects. (L1253) …

Matched symptoms: … to pulmonary edema, bloody sputum, and bronchial pneumonia. At high amounts, central nervous system ... depression may also occur, with symptoms such as weakness, dizziness, slow and shallow respiration ... , unconsciousness, and convulsions. Petroleum distillates are also irritating to the skin. (A594) …
Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched treatment: … Treatment is mainly symptomatic and supportive. Gastric lavage, emesis, and the administration of ... activated charcoal should be avoided, as vomiting increases the risk of aspiration. (A600) …
Matched description: … 2,4-Dimethylhexane is a hydrocarbon and one of the isomers of octane. Octanes may be found in gasoline. (L1296) …

Matched symptoms: … edema of the conjunctiva and eyelids. Ingestion cases epigastric pain, nausea, vomiting, headache ... muscular fasciculations, and disturbances of conciousness. In servere poisonings, convulsive attacks ... with opisthotonos and loss of conciousness have occurred. (T10) …
Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched treatment: … bronchospasm with inhaled beta2 agonist and oral or parenteral corticosteroids. In case of eye exposure ... Following oral exposure, the treatment is symptomatic and supportive and includes monitoring for ... the development of hypersensitivity reactions with respiratory distress. Provide adequate airway …
Matched description: … by the flowers of pyrethrums (Chrysanthemum cinerariaefolium and C. coccineum). Pyrethroids are ... individuals. They are usually broken apart by sunlight and the atmosphere in one or two days, and do not ... common in commercial products such as household insecticides and insect repellents. In the concentrations …

Matched symptoms: … Symptoms of low dose exposure include excessive salivation and eye-watering. Acute dose symptoms ... include severe nausea/vomiting, salivation, sweating, bradycardia, hypotension, collapse, and ... convulsions. Increasing muscle weakness is a possibility and may result in death if respiratory muscles are …
Matched carcinogenicity: … Not listed by IARC. IARC has assessed other furocoumarins, classifying 8-methoxypsoralen as ... carcinogenic to humans (Group 1), 5-methoxypsoralen as possibly carcinogenic to humans (Group 2A), and ... certain other furocoumarins as not being classifiable as to their carcinogenicity to humans (Group 3). (L135) …
Matched treatment: … effects of excess acetylcholine and reactivate AChE. Atropine can be used as an antidote in ... . Atropine is a muscarinic antagonist, and thus blocks the action of acetylcholine peripherally. ... bicarbonate. For skin contact, the skin should be washed with soap and water. If the compound has entered …
Matched description: … in a variety of vegetables and fruits, notably citrus fruits. The levels of furocoumarins present ... trifoliate Raf (L579). Furocoumarins, are phototoxic and photocarcinogenic. They intercalate DNA and ... example, in humans, bergamottin and dihydroxybergamottin are responsible for the 'grapefruit juice …

Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched description: … floridus (Carolina allspice) and other Calycanthus species. (+)-Calycanthine belongs to the family of ... (+)-Calycanthine is found in herbs and spices. (+)-Calycanthine is an alkaloid from Calycanthus ... carbon atom has been replaced by a nitrogen in each of the two rings. The naphthyridine skeleton can also …

Matched symptoms: … The most commonly reported symptoms accompanying acute and chronic overdoses are somnolence ... , agitation, hyperactivity, abnormal behavior, and gastrointestinal symptoms. …
Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched treatment: … An airway should be established. Monitoring of cardiac and vital signs is recommended, along with ... highly protein-bound, dialysis is not likely to be useful in the treatment of overdose. (L1712) ... appropriate symptomatic and supportive measures. Gastric lavage may be indicated if performed soon …
Matched description: … Atomoxetine is the first non-stimulant drug approved for the treatment of attention-deficit ... hyperactivity disorder (ADHD). It is sold in the form of the hydrochloride salt of atomoxetine. This ... chemical is manufactured and marketed under the brand name Strattera; by Eli Lilly and Company and as a …

Matched symptoms: … Exposure to high doses of ionizing radiation results in acute radiation syndrome, which can cause ... , fatigue, weakness, fever, birth defects, illness, infection, and death. (L1837, L1852) …
Matched treatment: … Treatment reversing the effects of irradiation is currently not possible. Anaesthetics and ... antiemetics are administered to counter the symptoms of exposure, as well as antibiotics for countering …
Matched description: … Radon is the chemical element of symbol Rn and atomic number 86. It is a rare radioactive gas ... , belonging to the noble gas series, and is formed as part of three radioactive decay chains that begin ... generated naturally by the decay of 238U and emits alpha particles. Because of its radioactivity and …
Matched synonyms: … Radon, isotope of mass 222 …

Matched symptoms: … Exposure to high doses of ionizing radiation results in acute radiation syndrome, which can cause ... , fatigue, weakness, fever, birth defects, illness, infection, and death. (L1837, L1852) …
Matched treatment: … Treatment reversing the effects of irradiation is currently not possible. Anaesthetics and ... antiemetics are administered to counter the symptoms of exposure, as well as antibiotics for countering …
Matched description: … extremely radioactive. Radium-226 is the most stable isotope, has a half-life of 1602 years, and decays ... calibration. Until the 1960s, radium was a component of the luminous paints used for watch and clock dials ... Radium is a radioactive chemical element which has the symbol Ra and atomic number 88. Its …
Matched synonyms: … Radium, isotope of mass 226 …

Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched treatment: … measures should be employed. Attention should be given to the maintenance of a patent airway and support of ... reversal of the sedative effects of midazolam and may be used in situations when an overdose with a benzodiazepine is known or suspected. (L1712) ... Treatment of midazolam overdosage is the same as that followed for overdosage with other …
Matched description: … A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in ... dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local ... anesthesia. The short duration and cardiorespiratory stability makes it useful in poor-risk …
Matched compound_type: … Hypnotic and Sedative …

Matched symptoms: … Acute exposure to PAHs causes irritation and inflammation of the skin and lung tissue. (A10) …
Matched carcinogenicity: … 3, not classifiable as to its carcinogenicity to humans. (L135) …
Matched description: … Coronene is one of over 100 different polycyclic aromatic hydrocarbons (PAHs). PAHs are chemicals ... usually found as a mixture containing two or more of these compounds. (L10) …

Matched symptoms: … Acute exposure to PAHs causes irritation and inflammation of the skin and lung tissue. (A10) …
Matched carcinogenicity: … Not listed by IARC. IARC has evaluated other PAHs (L2154). …
Matched description: … Ovalene is one of over 100 different polycyclic aromatic hydrocarbons (PAHs). PAHs are chemicals ... usually found as a mixture containing two or more of these compounds. (L10) …

Matched symptoms: … Symptoms of Clostridium difficile infection include bloating, constipation, and diarrhea with …
Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched treatment: … The antibiotics metronidazole and vancomycin have been shown to be effective against Clostridium difficile. (L1730) …
Matched description: … Toxins A and B are toxins from Clostridium difficile; they are the major pathogenicity factors of ... the antibiotic-associated diarrhea and the pseudomembranous colitis. Toxins A and B belong to the ... large clostridial cytotoxins family. Toxins A and B are also classified in the A-B bacterial toxin …

Matched symptoms: … Vestibular toxicity may result in vertigo, nausea and vomiting, dizziness and loss of balance. …
Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched description: … that binds to the 30S ribosome of susceptible organisms. Binding interferes with mRNA binding and ... acceptor tRNA sites and results in the production of non-functional or toxic peptides. ... A component of neomycin that is produced by Streptomyces fradiae. On hydrolysis it yields neamine …

Matched symptoms: … Acute exposure to PAHs causes irritation and inflammation of the skin and lung tissue. Some ... symptoms of hemolytic anemia are fatigue, lack of appetite, restlessness, and pale skin. Exposure to large ... amounts of 2-methylnapthalene may also cause nausea, vomiting, diarrhea, blood in the urine, and a yellow color to the skin. (A10, L12) …
Matched carcinogenicity: … Not directly listed by IARC. 2-Methylnaphthalene is found in coal tar mixtures, and occupational ... exposures during coal-tar distillation and during paving and roofing with coal-tar pitch are classified as carcinogenic to humans (Group 1). (L135) …
Matched description: … 2-Methylnaphthalene is one of over 100 different polycyclic aromatic hydrocarbons (PAHs). PAHs are ... . They are usually found as a mixture containing two or more of these compounds. (L10) …

Matched symptoms: … , and laboured breathing. Ingestion of HCCPD can cause abdominal pain,burning sensation, shock or ... Inhalation of HCCPD can cause cough, sore throat, headache, diarrhoea, dizziness, nausea, vomiting ... collapse. Dermal exposure can cause redness, pain and skin burns. Eye exposure can cause redness, pain, blurred vision, and severe deep burns. (L442) …
Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched treatment: … After oral exposure of HCCPD, gastric lavage is recommended. Following inhalation, move patient to ... respiratory tract irritation, bronchitis, or pneumonitis. Administer oxygen and assist ventilation ... as required. Treat bronchospasm with inhaled beta2 agonist and oral or parenteral corticosteroids …
Matched description: … is a manufactured chemical and does not occur naturally in the environment. It is made by adding ... , mirex, and pentac) referred to cyclodienes. Only two of these pesticides, endosulfan and pentac ... a group of related pesticides (aldrin, chlordane, dieldrin, endosulfan, endrin, heptachlor, isodrin …

Matched symptoms: … Methanol can produce sensory irritation and narcosis at airborne concentrations below those which produce organ system pathology. (T10) …
Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched description: … sequelae. Toxicity is due to the metabolic products of alcohol dehydrogenase (ADH) and aldehyde ... dehydrogenase. (A7768). The rapid and accurate diagnosis of toxic alcohol poisoning due to methanol (methyl ... serum levels of methanol using gas chromatography is expensive, time consuming and generally only available at major tertiary-care facilities. (A7769). …
Matched synonyms: … Spirit of wood …

Matched symptoms: … Diarrhea and cramps are the first symptoms. (L993) …
Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched treatment: … Treatment involves high dose penicillin as well as supportive care in cases of hepatic and renal …
Matched description: … mushrooms, most notably Amanita phalloides and several other members of the genus Amanita, as well as some Conocybe, Galerina and Lepiota mushroom species. (L1774) ... Amanullin is one of a group of at least eight Amatoxins found in several genera of poisonous …

Matched symptoms: … Diarrhea and cramps are the first symptoms. (L993) …
Matched carcinogenicity: … No indication of carcinogenicity to humans (not listed by IARC). …
Matched treatment: … Treatment involves high dose penicillin as well as supportive care in cases of hepatic and renal …
Matched description: … mushrooms, most notably Amanita phalloides and several other members of the genus Amanita, as well as ... Amaninamide is one of a group of at least eight Amatoxins found in several genera of poisonous ... some Conocybe, Galerina and Lepiota mushroom species. (L1774) …