Displaying toxin 2051 - 2075 of 3678 in total
T3DB ID Name
CAS Number
Formula
Weight
StructureTypeMechanism of Toxicity
T3D2523Scyllatoxin
142948-19-4
Not Available
3430.130 g/mol
T3d2523
  • Amide
  • Amine
  • Animal Toxin
  • Natural Compound
  • Organic Compound
  • Protein
  • Scorpion Toxin
Scyllatoxin blocks small conductance calcium-activated potassium channels. This inhibits the slow after-hyperpolarisation that follows an action potential in some nerv...more
Number of Targets: 3
T3D2524Slotoxin
144026-79-9
Not Available
4091.850 g/mol
T3d2524
  • Amide
  • Amine
  • Animal Toxin
  • Natural Compound
  • Organic Compound
  • Protein
  • Scorpion Toxin
Slotoxin reversibly blocks the high conductance calcium-activated potassium channels composed of only alpha-subunits and irreversibly blocks the high conductance calci...more
Number of Targets: 3
T3D2525Tamapin
508220-81-3
Not Available
3465.100 g/mol
T3d2525
  • Amide
  • Amine
  • Animal Toxin
  • Natural Compound
  • Organic Compound
  • Protein
  • Scorpion Toxin
Tamapin is a selective, potent, and reversible blocker of small conductance calcium-dependent potassium channels. It inhibits SK2 with the highest affinity, SK3 with a...more
Number of Targets: 3
T3D2526Tityustoxin (Tityus serrulatus )
39465-37-7
Not Available
6997.935 g/mol
T3d2526
  • Amide
  • Amine
  • Animal Toxin
  • Natural Compound
  • Organic Compound
  • Protein
  • Scorpion Toxin
Tityustoxin binds to voltage-dependent sodium and potassium channels. alpha-Type tityustoxin inhibits the inactivation of the activated sodium channels by binding to s...more
Number of Targets: 14
T3D2527Batrachotoxin
23509-16-2
C31H42N2O6
538.675 g/mol
Thumb
  • Amide
  • Amine
  • Animal Toxin
  • Ester
  • Ether
  • Frog/Toad Toxin
  • Natural Compound
  • Organic Compound
Batrachotoxins act on sodium channels by modifying both their ion selectivity and voltage sensitivity. By increasing the permeability of the cell membrane, the cell is...more
Number of Targets: 14
T3D2528Histrionicotoxin
34272-51-0
C19H25NO
283.408 g/mol
Thumb
  • Amine
  • Animal Toxin
  • Frog/Toad Toxin
  • Natural Compound
  • Organic Compound
Histrionicotoxin is a potent non-competitive antagonist of nicotinic acetylcholine receptors. (L1072)
Number of Targets: 16
T3D2529Pumiliotoxin
73376-35-9
C16H29NO
251.408 g/mol
Thumb
  • Amine
  • Animal Toxin
  • Frog/Toad Toxin
  • Natural Compound
  • Organic Compound
Pumiliotoxin affects voltage-gated calcium channels, interfering with muscle contraction in the heart and skeletal muscle. They also may block sodium and potassium cha...more
Number of Targets: 25
T3D2530Epibatidine
140111-52-0
C11H13ClN2
208.687 g/mol
Thumb
  • Amine
  • Animal Toxin
  • Frog/Toad Toxin
  • Natural Compound
  • Organic Compound
  • Organochloride
Epibatidine works by binding and activating nicotinic acetylcholine receptors. (L1074)
Number of Targets: 17
T3D2531Allopumiliotoxin
73376-38-2
C16H29NO2
267.407 g/mol
Thumb
  • Amine
  • Animal Toxin
  • Frog/Toad Toxin
  • Natural Compound
  • Organic Compound
Allopumiliotoxins may affect sodium and potassium channels in cells and inhibit calcium-dependent ATPase. (L1077, A313, A315)
Number of Targets: 11
T3D2532Arenobufagin
464-74-4
C24H32O6
416.507 g/mol
Thumb
  • Animal Toxin
  • Ester
  • Frog/Toad Toxin
  • Natural Compound
  • Organic Compound
Arenobufagin blocks the sodium/potassium pump in heart tissue. (L1078)
Number of Targets: 8
T3D2534Bufotenin
487-93-4
C12H16N2O
204.268 g/mol
Thumb
  • Amine
  • Animal Toxin
  • Frog/Toad Toxin
  • Fungal Toxin
  • Metabolite
  • Natural Compound
  • Organic Compound
Bufotenin is a neurotoxin similar to the mushroom toxin psilocin. Thus it likely acts as a partial agonist at the 5-HT2A serotonin receptor in the brain where it mimic...more
Number of Targets: 4
T3D2535Cinobufagin
470-37-1
C26H34O6
442.545 g/mol
Thumb
  • Animal Toxin
  • Ester
  • Ether
  • Frog/Toad Toxin
  • Natural Compound
  • Organic Compound
Cinobufagin blocks the sodium/potassium pump in heart tissue. (L1083, L1084)
Number of Targets: 0
T3D2536Marinobufagenin
470-42-8
C24H32O5
400.508 g/mol
Thumb
  • Animal Toxin
  • Ester
  • Ether
  • Frog/Toad Toxin
  • Natural Compound
  • Organic Compound
Marinobufagin blocks the sodium/potassium pump in heart tissue. (L1084, L1085)
Number of Targets: 0
T3D2537alpha-Bungarotoxin
11032-79-4
Not Available
10285.030 g/mol
T3d2537
  • Amide
  • Amine
  • Animal Toxin
  • Natural Compound
  • Organic Compound
  • Protein
  • Snake Venom
alpha-Bungarotoxin binds irreversibly and competitively to muscular and neuronal nicotinic acetylcholine receptors. This produces peripheral paralysis by blocking neur...more
Number of Targets: 8
T3D2538beta-Bungarotoxin
12778-32-4
Not Available
9571.020 g/mol
T3d2538
  • Amide
  • Amine
  • Animal Toxin
  • Natural Compound
  • Organic Compound
  • Protein
  • Snake Venom
beta-Bungarotoxin acts at the presynaptic terminal, where it causes release of acetylcholine and subsequent exhaustion of acetylcholine stores in the nerve terminal by...more
Number of Targets: 23
T3D2539Calciseptine
134710-25-1
Not Available
7044.155 g/mol
T3d2539
  • Amide
  • Amine
  • Animal Toxin
  • Natural Compound
  • Organic Compound
  • Protein
  • Snake Venom
Calciseptine is a specific blocker of the L-type calcium channel, and as a result also a smooth muscle relaxant and an inhibitor of cardiac contractions. (T170)
Number of Targets: 8
T3D2540Calcicludine
178037-96-2
Not Available
6986.205 g/mol
T3d2540
  • Amide
  • Amine
  • Animal Toxin
  • Natural Compound
  • Organic Compound
  • Protein
  • Snake Venom
Calcicludine inhibits high-voltage-activated calcium channels, especially of the L-type. (L1092)
Number of Targets: 10
T3D2541Cardiotoxin (Naja atra)
155808-00-7
Not Available
8991.970 g/mol
T3d2541
  • Amide
  • Amine
  • Animal Toxin
  • Natural Compound
  • Organic Compound
  • Protein
  • Snake Venom
Cardiotoxin binds to the cell membrane and depolarizes cardiomyocytes. It also shows lytic activities on many other cells, including red blood cells. It also targets t...more
Number of Targets: 11
T3D2542Crotamine
58740-15-1
Not Available
7518.980 g/mol
T3d2542
  • Amide
  • Amine
  • Animal Toxin
  • Natural Compound
  • Organic Compound
  • Protein
  • Snake Venom
Crotamine specifically modifies voltage-sensitive sodium channels, it exhibits analgesic activity and causes severe muscle necrosis by a non-enzymatic mechanism. It al...more
Number of Targets: 14
T3D2543Crotoxin
9007-40-3
Not Available
15272.965 g/mol
T3d2543
  • Amide
  • Amine
  • Animal Toxin
  • Natural Compound
  • Organic Compound
  • Protein
  • Snake Venom
Crotoxin inhibits neuromuscular transmission by presynaptically blocking acetylcholine release from the nerve termini. (T170)
Number of Targets: 0
T3D2544Convulxin
37206-04-5
Not Available
18140.725 g/mol
T3d2544
  • Amide
  • Amine
  • Animal Toxin
  • Natural Compound
  • Organic Compound
  • Protein
  • Snake Venom
Convulxin binds to the platelet and collagen receptor, glycoprotein VI (GPVI). This causes platelet activation in the blood forming clots and a build up of pressure, w...more
Number of Targets: 1
T3D2545Dendrotoxin (Dendroaspis polylepis polylepis)
119128-61-9
Not Available
7155.305 g/mol
T3d2545
  • Amide
  • Amine
  • Animal Toxin
  • Natural Compound
  • Organic Compound
  • Protein
  • Snake Venom
Dendrotoxins block particular subtypes of voltage-gated potassium channels in neurons, thereby prolonging the duration of action potentials and enhancing the release o...more
Number of Targets: 23
T3D2546Dendrotoxin (Dendroaspis angusticeps)
74504-53-3
Not Available
3417.825 g/mol
T3d2546
  • Amide
  • Amine
  • Animal Toxin
  • Natural Compound
  • Organic Compound
  • Protein
  • Snake Venom
Dendrotoxins block particular subtypes of voltage-gated potassium channels in neurons, thereby prolonging the duration of action potentials and enhancing the release o...more
Number of Targets: 23
T3D2547Taicatoxin
112154-17-3
Not Available
9711.255 g/mol
No structure small
  • Amide
  • Amine
  • Animal Toxin
  • Natural Compound
  • Organic Compound
  • Protein
  • Snake Venom
Taicatoxin blocks the voltage-dependent L-type calcium channels from the heart and on the small conductance calcium-activated potassium channels in the brain. (L1105)
Number of Targets: 11
T3D2549Eledoisin (Eledone cirrhosa)
69-25-0
Not Available
1206.410 g/mol
T3d2549
  • Amide
  • Amine
  • Animal Toxin
  • Marine Toxin
  • Natural Compound
  • Organic Compound
  • Protein
Eledoisin is a tachykinin peptide. Tachykinins excite neurons, evoke behavioural responses, are potent vasodilators and secretagogues, and contract (directly or indire...more
Number of Targets: 3
Displaying toxin 2051 - 2075 of 3678 in total