Browsing Toxins By Category
Displaying toxin 2176 - 2200 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D2499 | Huwentoxin 526224-73-7 | Not Available 9318.830 g/mol |  |
| Huwentoxin blocks neuromuscular transmission by binding to the nicotinic acetylcholine receptor, which affects the release of neurotransmitters from autonomic nerve en...more Number of Targets: 17 |
| T3D2646 | Hydralysin (Chlorohydra viridissima) Not Available | Not Available 26212.075 g/mol |  |
| Hydralysin is a cytolytic toxin. It binds to erythrocyte membranes and has weak hemolytic activity, probably mediated by oligomerization and pore formation. (T170) Number of Targets: 0 |
| T3D0084 | Hydrazine 302-01-2 | H4N2 32.045 g/mol |  |
| At least two mechanisms of action have been observed. One involves the direct binding of those hydrazines with a free amino group (hydrazine and 1,1-dimethylhydrazine)...more Number of Targets: 0 |
| T3D4968 | Hydrochloric acid 7647-01-0 | ClH 36.461 g/mol |  |
| Both hydrogen chloride gas and hydrochloric acid are highly corrosive. Many strong acids cause tissue burns through the denaturation of proteins and partial hydrolysi...more Number of Targets: 0 |
| T3D4781 | Hydrochlorothiazide 58-93-5 | C7H8ClN3O4S2 297.739 g/mol |  |
| Hydrochlorothiazide, a thiazide diuretic, inhibits water reabsorption in the nephron by inhibiting the sodium-chloride symporter (SLC12A3) in the distal convoluted tub...more Number of Targets: 9 |
| T3D2941 | Hydrocodone 125-29-1 | C18H21NO3 299.364 g/mol |  |
| Hydrocodone acts as a weak agonist at OP1, OP2, and OP3 opiate receptors within the central nervous system (CNS). Hydrocodone primarily affects OP3 receptors, which ar...more Number of Targets: 3 |
| T3D1732 | Hydrogen bromide 10035-10-6 | BrH 80.912 g/mol |  |
| Bromine is a powerful oxidizing agent and is able to release oxygen free radicals from the water in mucous membranes. These free radicals are also potent oxidizers and...more Number of Targets: 6 |
| T3D0133 | Hydrogen cyanide 74-90-8 | CHN 27.025 g/mol |  |
| Organic nitriles decompose into cyanide ions both in vivo and in vitro. Consequently the primary mechanism of toxicity for organic nitriles is their production of toxi...more Number of Targets: 44 |
| T3D0247 | Hydrogen fluoride 7664-39-3 | FH 20.006 g/mol |  |
| In addition to being a highly corrosive liquid, hydrofluoric acid is also a contact poison. As with most acids HF can cause tissue burns through the denaturation of pr...more Number of Targets: 7 |
| T3D1651 | Hydrogen isocyanide 6914-07-4 | CHN 27.025 g/mol |  |
| Organic nitriles decompose into cyanide ions both in vivo and in vitro. Consequently the primary mechanism of toxicity for organic nitriles is their production of toxi...more Number of Targets: 39 |
| T3D1834 | Hydrogen selenide 7783-07-5 | H2Se 80.980 g/mol |  |
| Selenium readily substitutes for sulfur in biomolecules and in many biochemical reactions, especially when the concentration of selenium is high and the concentration ...more Number of Targets: 0 |
| T3D0191 | Hydrogen sulfide 7783-06-04 | H2S 34.081 g/mol |  |
| Although very pungent at first, hydrogen sulfide quickly deadens the sense of smell, so potential victims may be unaware of its presence until it is too late. Hydrogen...more Number of Targets: 1 |
| T3D1590 | Hydrogen tetrachloro-palladate(II) 16970-55-1 | Cl4H2Pd 250.250 g/mol |  |
| Due to their ability to form strong complexes with both inorganic and organic ligands, palladium ions can disturb cellular equilibria, replace other essential ions, an...more Number of Targets: 6 |
| T3D2752 | Hydromorphone 466-99-9 | C17H19NO3 285.338 g/mol |  |
| Hydromorphone is a narcotic analgesic; its principal therapeutic effect is relief of pain. Hydromorphone interacts predominantly with the opioid mu-receptors. These mu...more Number of Targets: 3 |
| T3D4577 | Hydroquinone 123-31-9 | C6H6O2 110.111 g/mol |  |
| Not Available Number of Targets: 11 |
| T3D0677 | Hydroxocobalamin 13422-51-0 | C62H89CoN13O15P 1346.355 g/mol |  |
| Vitamin B12 exists in four major forms referred to collectively as cobalamins; deoxyadenosylcobalamin, methylcobalamin, hydroxocobalamin, and cyanocobalamin. Two of th...more Number of Targets: 45 |
| T3D3512 | Hydroxychloroquine 118-42-3 | C18H26ClN3O 335.872 g/mol |  |
| Although the exact mechanism of action is unknown, it may be based on ability of hydroxychloroquine to bind to and alter DNA. Hydroxychloroquine has also has been foun...more Number of Targets: 3 |
| T3D3562 | Hydroxylammonium nitrate 13465-08-2 | H4N2O4 96.043 g/mol |  |
| Nitrate's toxicity is a result of it's conversion to nitrite once in the body. Nitrite causes the autocatalytic oxidation of oxyhemoglobin to hydrogen peroxide and met...more Number of Targets: 9 |
| T3D4304 | Hydroxypropionic acid 503-66-2 | C3H6O3 90.078 g/mol |  |
| 3-hydroxypropionic acid (3HP) toxicity is mediated by 3-hydroxypropionic aldehyde (reuterin). 3HP toxicity is also proposed to be related to inhibition of the chorisma...more Number of Targets: 0 |
| T3D1252 | Hydroxytriphenylstannane 76-87-9 | C18H19OSn 370.050 g/mol |  |
| Organotin compounds produce neurotoxic and immunotoxic effects. Organotins may directly activate glial cells contributing to neuronal cell degeneration by local releas...more Number of Targets: 45 |
| T3D4767 | Hydroxyurea 127-07-1 | CH4N2O2 76.055 g/mol |  |
| Hydroxyurea is converted to a free radical nitroxide (NO) in vivo, and transported by diffusion into cells where it quenches the tyrosyl free radical at the active sit...more Number of Targets: 2 |
| T3D2823 | Hydroxyzine 68-88-2 | C21H27ClN2O2 374.904 g/mol |  |
| Hydroxyzine competes with histamine for binding at H1-receptor sites on the effector cell surface, resulting in suppression of histaminic edema, flare, and pruritus. T...more Number of Targets: 4 |
| T3D3095 | Hyoscyamine 101-31-5 | C17H23NO3 289.369 g/mol |  |
| Hyoscyamine is an anticholinergic, specifically an antimuscarinic, and works by blocking the action of acetylcholine at parasympathetic sites in smooth muscle, secreto...more Number of Targets: 5 |
| T3D4025 | Hypoglycin B 502-37-4 | C12H18N2O5 270.282 g/mol |  |
| Generally, hypoglycin is an amino acid and chemically related to lysine. It competitively binds to enzymes used in the catabolism of lysine and is the reason why it an...more Number of Targets: 0 |
| T3D4150 | Hypoxanthine 68-94-0 | C5H4N4O 136.112 g/mol |  |
| Hypoxanthine is a poorly soluble compound. As a result high concentrations of serum hypoxanthine can lead to the formation of kidney stones which can, over the long t...more Number of Targets: 4 |