Browsing Toxins By Category
Displaying toxin 2151 - 2175 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D0022 | Hexachlorobutadiene 87-68-3 | C4Cl6 260.761 g/mol |  |
| It is believed that intermediates produced by modification of the S- 1,1,2,3,4-pentachlorodienyl cysteine derivative metabolite by gamma-glutamyltransferase are respon...more Number of Targets: 40 |
| T3D0148 | Hexachlorocyclohexane, technical Grade 608-73-1 | C6H6Cl6 290.830 g/mol |  |
| Hexachlorocyclohexane is a neurotoxin that interferes with GABA neurotransmitter function by interacting with the GABA-A receptor-chloride channel complex at the picro...more Number of Targets: 32 |
| T3D0165 | Hexachlorocyclopentadiene 77-47-4 | C5Cl6 272.772 g/mol |  |
| HCCPD may interact with the microsomes that binds to secretory molecules and changes their ability to be transported from the cell. It can be postulated, that some of ...more Number of Targets: 42 |
| T3D4514 | Hexaconazole 79983-71-4 | C14H17Cl2N3O 314.210 g/mol |  |
| Not Available Number of Targets: 13 |
| T3D4286 | Hexacosanoic acid 506-46-7 | C26H52O2 396.690 g/mol |  |
| Adrenoleukodystrophy (ALD) is caused by mutations in ABCD1, a gene located on the X chromosome that codes for ALD, a peroxisomal membrane transporter protein. The exac...more Number of Targets: 0 |
| T3D1872 | Hexafluoroantimonic acid 16950-06-4 | F6HSb 236.760 g/mol |  |
| The inhalation data suggests that the myocardium is a target of antimony toxicity. It is possible that antimony affects circulating glucose by interfering with enzymes...more Number of Targets: 20 |
| T3D1286 | Hexakis(2-methyl-2-phenylpropyl)distannoxane 13356-08-6 | C60H80OSn2 1054.700 g/mol |  |
| Organotin compounds produce neurotoxic and immunotoxic effects. Organotins may directly activate glial cells contributing to neuronal cell degeneration by local releas...more Number of Targets: 12 |
| T3D1661 | Hexamethylene diisocyanate 822-06-0 | C8H12N2O2 168.193 g/mol |  |
| Cyanide is an inhibitor of cytochrome c oxidase in the fourth complex of the electron transport chain (found in the membrane of the mitochondria of eukaryotic cells). ...more Number of Targets: 40 |
| T3D0676 | Hexamminecobalt(III) chloride 10534-89-1 | Cl3CoH18N6 267.475 g/mol |  |
| Cobalt is believed to exhibit its toxicity through a oxidant-based and free radical-based processes. It produces oxygen radicals and may be oxidized to ionic cobalt, c...more Number of Targets: 35 |
| T3D4181 | Hexanal 66-25-1 | C6H12O 100.159 g/mol |  |
| Uremic toxins such as hexanal are actively transported into the kidneys via organic ion transporters (especially OAT3). Increased levels of uremic toxins can stimulate...more Number of Targets: 4 |
| T3D2403 | Hexane 110-54-3 | C6H14 86.175 g/mol |  |
| Hexane's toxicity is caused by it neurotoxic metabolite, 2,5-hexanedione. It damages the central and peripheral nervous system by causing axonal swelling and degenerat...more Number of Targets: 6 |
| T3D0018 | Hexavalent chromium 18540-29-9 | Cr 51.996 g/mol |  |
| Hexavalent chromium's carcinogenic effects are caused by its metabolites, pentavalent and trivalent chromium. The DNA damage may be caused by hydroxyl radicals produce...more Number of Targets: 5 |
| T3D3857 | Hexazinone 51235-04-2 | C12H20N4O2 252.313 g/mol |  |
| Not Available Number of Targets: 4 |
| T3D4740 | Hexestrol 84-16-2 | C18H22O2 270.366 g/mol |  |
| Not Available Number of Targets: 16 |
| T3D3039 | Hexobarbital 56-29-1 | C12H16N2O3 236.267 g/mol |  |
| Hexobarbital binds at a distinct binding site associated with a Cl- ionopore at the GABA-A receptor, increasing the duration of time for which the Cl- ionopore is open...more Number of Targets: 11 |
| T3D4855 | Hexylresorcinol 136-77-6 | C12H18O2 194.270 g/mol |  |
| Not Available Number of Targets: 8 |
| T3D4515 | Hexythiazox 78587-05-0 | C17H21ClN2O2S 352.879 g/mol |  |
| Not Available Number of Targets: 11 |
| T3D4159 | Hippuric acid 495-69-2 | C9H9NO3 179.173 g/mol |  |
| Uremic toxins such as hippuric acid are actively transported into the kidneys via organic ion transporters (especially OAT3). Increased levels of uremic toxins can sti...more Number of Targets: 4 |
| T3D2528 | Histrionicotoxin 34272-51-0 | C19H25NO 283.408 g/mol |  |
| Histrionicotoxin is a potent non-competitive antagonist of nicotinic acetylcholine receptors. (L1072) Number of Targets: 16 |
| T3D2492 | Holocyclotoxin 88254-04-0 | Not Available 7834.125 g/mol |  |
| Holocyclotoxin produces paralysis by acting at the neuromuscular junction. (A2834) Number of Targets: 0 |
| T3D4161 | Homocysteine 454-29-5 | C4H9NO2S 135.185 g/mol |  |
| Nitrosylation converts homocysteine (Hcy) into a methionine analogue, S-nitroso-Homocysteine, which can substitute for methionine in protein synthesis in biological sy...more Number of Targets: 5 |
| T3D4287 | Homogentisic acid 451-13-8 | C8H8O4 168.147 g/mol |  |
| Extremely high levels of homogentisic acid are found in patients with the inborn error of metabolism (IEM) called Alkaptonuria. Homogentisic acid spontaneously undergo...more Number of Targets: 0 |
| T3D2581 | Hongotoxin 203526-59-4 | Not Available 4226.080 g/mol |  |
| Hongotoxin inhibits voltage-gated potassium channels. (L1049) Number of Targets: 4 |
| T3D3858 | HPTE 2971-36-0 | C14H11Cl3O2 317.595 g/mol |  |
| 2,2-bis(p-hydroxyphenyl)-1,1, 1-trichloroethane (HPTE), acts as an estrogen analogue. HPTE is an estrogen receptor alpha agonist, and also acts as an antagonist at the...more Number of Targets: 29 |
| T3D3673 | HT-2 Toxin 26934-87-2 | C22H32O8 424.485 g/mol |  |
| Unlike many other mycotoxins, trichothecenes do not require metabolic activation to exert their biological activity, instead directly reacting with cellular components...more Number of Targets: 2 |