Browsing Toxins By Category
Displaying toxin 2076 - 2100 of 3678 in total
T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
---|---|---|---|---|---|
T3D2857 | Galantamine 357-70-0 | C17H21NO3 287.354 g/mol |
| Galantamine is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholinest...more Number of Targets: 19 | |
T3D0287 | Gallium arsenide 1303-00-0 | AsGa 144.645 g/mol |
| Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co...more Number of Targets: 44 | |
T3D2410 | Gallium phosphide 12063-98-8 | GaP 100.697 g/mol |
| Phosphine inhibits cytochrome c oxidase, preventing mitochondrial oxidative phosphorylation. This non-competitive inhibition prevents cellular respiration and leads to...more Number of Targets: 20 | |
T3D1831 | Gallium(II) selenide 12024-11-2 | GaSe 148.680 g/mol |
| Selenium readily substitutes for sulfur in biomolecules and in many biochemical reactions, especially when the concentration of selenium is high and the concentration ...more Number of Targets: 0 | |
T3D1730 | Gallium(III) bromide 13450-88-9 | Br3Ga 309.435 g/mol |
| Bromine is a powerful oxidizing agent and is able to release oxygen free radicals from the water in mucous membranes. These free radicals are also potent oxidizers and...more Number of Targets: 6 | |
T3D1832 | Gallium(III) selenide 12024-24-7 | Ga2Se3 376.330 g/mol |
| Selenium readily substitutes for sulfur in biomolecules and in many biochemical reactions, especially when the concentration of selenium is high and the concentration ...more Number of Targets: 0 | |
T3D1568 | gamma-Aluminum oxide hydroxide 1318-23-6 | AlHO2 59.988 g/mol |
| The main target organs of aluminum are the central nervous system and bone. Aluminum binds with dietary phosphorus and impairs gastrointestinal absorption of phosphoru...more Number of Targets: 3 | |
T3D3586 | gamma-Amanitin 21150-23-2 | Not Available 3706.230 g/mol |
| The major toxic mechanism of amatoxins is the inhibition of RNA polymerase II, a vital enzyme in the synthesis of messenger RNA (mRNA), microRNA, and small nuclear RNA...more Number of Targets: 14 | |
T3D4250 | Gamma-Aminobutyric acid 56-12-2 | C4H9NO2 103.120 g/mol |
| Not Available Number of Targets: 10 | |
T3D2562 | Gamma-Butyrolactone 96-48-0 | C4H6O2 86.089 g/mol |
| Gamma-butyrolactone is rapidly converted to gamma-hydroxybutyrate. This may account for the subsequent central nervous system depressant. Gamma-butyrolactone is an ane...more Number of Targets: 1 | |
T3D4915 | gamma-Cyclodextrin 17465-86-0 | C48H80O40 1297.125 g/mol |
| Not Available Number of Targets: 1 | |
T3D0032 | gamma-Hexachlorocyclohexane 58-89-9 | C6H6Cl6 290.830 g/mol |
| Hexachlorocyclohexane is a neurotoxin that interferes with GABA neurotransmitter function by interacting with the GABA-A receptor-chloride channel complex at the picro...more Number of Targets: 53 | |
T3D4890 | Gamma-terpinene 99-85-4 | C10H16 136.234 g/mol |
| Not Available Number of Targets: 1 | |
T3D2968 | Gatifloxacin 112811-59-3 | C19H22FN3O4 375.394 g/mol |
| The bactericidal action of Gatifloxacin results from inhibition of the enzymes topoisomerase II (DNA gyrase) and topoisomerase IV, which are required for bacterial DNA...more Number of Targets: 3 | |
T3D4071 | Gelsemine 509-15-9 | C20H22N2O2 322.401 g/mol |
| Gelsemine has convulsant effects with a similar mechanism of action to strychnine. Strychnine is a neurotoxin which acts as an antagonist of glycine and acetylcholine ...more Number of Targets: 0 | |
T3D4809 | Gemfibrozil 25812-30-0 | C15H22O3 250.333 g/mol |
| Gemfibrozil increases the activity of extrahepatic lipoprotein lipase (LL), thereby increasing lipoprotein triglyceride lipolysis. It does so by activating Peroxisome ...more Number of Targets: 2 | |
T3D4821 | Gentian Violet 14426-25-6 | C25H30N3 372.525 g/mol |
| Gentian Violet is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholin...more Number of Targets: 41 | |
T3D4837 | Geranyl acetate 105-87-3 | C12H20O2 196.286 g/mol |
| Not Available Number of Targets: 1 | |
T3D1833 | Germanium selenide 12065-10-0 | GeSe 151.600 g/mol |
| Selenium readily substitutes for sulfur in biomolecules and in many biochemical reactions, especially when the concentration of selenium is high and the concentration ...more Number of Targets: 0 | |
T3D3604 | Gliotoxin 67-99-2 | C13H14N2O4S2 326.391 g/mol |
| Gliotoxin possesses immunosuppressive properties as it may suppress and cause apoptosis in certain types of cells of the immune system, including neutrophils, eosinop...more Number of Targets: 12 | |
T3D2483 | Glipizide 29094-61-9 | C21H27N5O4S 445.535 g/mol |
| Sulfonylureas likely bind to ATP-sensitive potassium-channel receptors on the pancreatic cell surface, reducing potassium conductance and causing depolarization of the...more Number of Targets: 3 | |
T3D0812 | Glufosinate 51276-47-2 | C5H12NO4P 181.127 g/mol |
| Glufosinate irreversibly inhibits the enzyme glutamine synthetase, which decreases ammonia detoxification. Increased ammonia levels lead to impairment of photorespirat...more Number of Targets: 1 | |
T3D4358 | Glutaconic acid 1724-02-3 | C5H6O4 130.099 g/mol |
| Accumulating trans-glutaconic (TG) acids has been proposed to be involved in the development of the striatal degeneration seen in children with glutaric acidemia type ...more Number of Targets: 1 | |
T3D4844 | Glutaral 111-30-8 | C5H8O2 100.116 g/mol |
| Not Available Number of Targets: 3 | |
T3D4359 | Glutaric acid 110-94-1 | C5H8O4 132.115 g/mol |
| Accumulation of glutaric acid in the body has been shown to be toxic. The accumulation of glutaric acid ranging from slightly or intermittently elevated urinary glutar...more Number of Targets: 1 |