Browsing Toxins By Category
Displaying toxin 1951 - 1975 of 3678 in total
T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
---|---|---|---|---|---|
T3D4568 | Ethyl loflazepate 29177-84-2 | C18H14ClFN2O3 360.767 g/mol |
| Benzodiazepines bind nonspecifically to benzodiazepine receptors BNZ1, which mediates sleep, and BNZ2, which affects affects muscle relaxation, anticonvulsant activity...more Number of Targets: 18 | |
T3D1675 | Ethyl thiocyanate 542-90-5 | C3H5NS 87.143 g/mol |
| Organic nitriles decompose into cyanide ions both in vivo and in vitro. Consequently the primary mechanism of toxicity for organic nitriles is their production of toxi...more Number of Targets: 39 | |
T3D1551 | Ethylaluminum sesquichloride 12075-68-2 | C6H15Al2Cl3 247.505 g/mol |
| The main target organs of aluminum are the central nervous system and bone. Aluminum binds with dietary phosphorus and impairs gastrointestinal absorption of phosphoru...more Number of Targets: 3 | |
T3D4185 | Ethylamine 75-04-7 | C2H7N 45.084 g/mol |
| Uremic toxins such as ethylamine are actively transported into the kidneys via organic ion transporters (especially OAT3). Increased levels of uremic toxins can stimul...more Number of Targets: 3 | |
T3D0099 | Ethylbenzene 100-41-4 | C8H10 106.165 g/mol |
| Changes in the integrity of the cell membrane after partitioning of ethylbenzene into the lipid bilayer may subsequently affect the function of membrane, particularly ...more Number of Targets: 17 | |
T3D1309 | Ethyldichloroarsine 598-14-1 | C2H5AsCl2 174.889 g/mol |
| Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co...more Number of Targets: 45 | |
T3D1682 | Ethylene cyanohydrin 109-78-4 | C3H5NO 71.078 g/mol |
| Cyanide is an inhibitor of cytochrome c oxidase in the fourth complex of the electron transport chain (found in the membrane of the mitochondria of eukaryotic cells). ...more Number of Targets: 39 | |
T3D0772 | Ethylene glycol 107-21-1 | C2H6O2 62.068 g/mol |
| Ethylene glycol is metabolized by alcohol dehydrogenase to glycoaldehyde, which is then metabolized to glycolic, glyoxylic, and oxalic acids. These acids, along with e...more Number of Targets: 0 | |
T3D4207 | Ethylene Oxide 75-21-8 | C2H4O 44.053 g/mol |
| Ethylene oxide is an alkylating agent. The addition of alkyl groups to proteins, DNA, and RNA by binding to the sulfhydryl and hydroxyl, amino, and carboxyl groups, pr...more Number of Targets: 0 | |
T3D4503 | Ethylenethiourea 96-45-7 | C3H6N2S 102.158 g/mol |
| Not Available Number of Targets: 2 | |
T3D4461 | Ethylmalonic acid 601-75-2 | C5H8O4 132.115 g/mol |
| Ethylmalonic acid is identified in the urine of patients with short-chain acyl-coenzyme A dehydrogenase deficiency, which is a fatty acid metabolism disorder. Number of Targets: 1 | |
T3D1351 | Ethylmercuric phosphate 2235-25-8 | C2H7HgO4P 326.640 g/mol |
| High-affinity binding of the divalent mercuric ion to thiol or sulfhydryl groups of proteins is believed to be the major mechanism for the activity of mercury. Through...more Number of Targets: 50 | |
T3D1359 | Ethylmercury chloride 107-27-7 | C2H5ClHg 265.100 g/mol |
| High-affinity binding of the divalent mercuric ion to thiol or sulfhydryl groups of proteins is believed to be the major mechanism for the activity of mercury. Through...more Number of Targets: 51 | |
T3D3978 | Ethylparaben 120-47-8 | C9H10O3 166.174 g/mol |
| Not Available Number of Targets: 8 | |
T3D4828 | Ethylphosphate 78-40-0 | C2H7O4P 126.048 g/mol |
| Not Available Number of Targets: 1 | |
T3D1340 | Ethyltrimethyl lead 1762-26-1 | C5H14Pb 281.400 g/mol |
| Lead mimics other biologically important metals, such as zinc, calcium, and iron, competing as cofactors for many of their respective enzymatic reactions. For example,...more Number of Targets: 29 | |
T3D3483 | Etidronic acid 7414-83-7 | C2H8O7P2 206.028 g/mol |
| Bisphosphonates, when attached to bone tissue, are absorbed by osteoclasts, the bone cells that breaks down bone tissue. Although the mechanism of action of non-nitrog...more Number of Targets: 4 | |
T3D4584 | Etizolam 40054-69-1 | C17H15ClN4S 342.846 g/mol |
| Benzodiazepines bind nonspecifically to benzodiazepine receptors BNZ1, which mediates sleep, and BNZ2, which affects affects muscle relaxation, anticonvulsant activity...more Number of Targets: 18 | |
T3D4695 | Etoposide 33419-42-0 | C29H32O13 588.557 g/mol |
| Etoposide inhibits DNA topoisomerase II, thereby inhibiting DNA re-ligation. This causes critical errors in DNA synthesis at the premitotic stage of cell division and ...more Number of Targets: 2 | |
T3D3834 | Etoxazole 153233-91-1 | C21H23F2NO2 359.410 g/mol |
| Not Available Number of Targets: 26 | |
T3D3835 | Etridiazole 2593-15-9 | C5H5Cl3N2OS 247.530 g/mol |
| Not Available Number of Targets: 3 | |
T3D4879 | Eugenol 97-53-0 | C10H12O2 164.201 g/mol |
| Not Available Number of Targets: 5 | |
T3D2607 | Exotoxin A (Pseudomonas aeruginosa) Not Available | Not Available 69283.345 g/mol |
| Pseudomonas exotoxin has exactly the same mechanism of action as the diphtheria toxin; it causes the ADP ribosylation of eucaryotic elongation factor 2 resulting in in...more Number of Targets: 1 | |
T3D4504 | Famoxadone 131807-57-3 | C22H18N2O4 374.389 g/mol |
| Not Available Number of Targets: 31 | |
T3D4811 | Farnesol 4602-84-0 | C15H26O 222.366 g/mol |
| Not Available Number of Targets: 3 |