Browsing Toxins By Category
Displaying toxin 1276 - 1300 of 3678 in total
T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
---|---|---|---|---|---|
T3D1725 | Bronidox 30007-47-7 | C4H6BrNO4 211.999 g/mol |
| Bronidox likely acts as an oxidizing agent that leads to oxidation of free sulfhydryls in essential enzymes. One of the most probable protein targets is the TRPA1 ion...more Number of Targets: 1 | |
T3D1724 | Bronopol 52-51-7 | C3H6BrNO4 199.988 g/mol |
| While Bronopol is not in itself a nitrosating agent, under conditions where it decomposes (alkaline solution and/or elevated temperatures) it can liberate nitrite and ...more Number of Targets: 9 | |
T3D4573 | Brotizolam 57801-81-7 | C15H10BrClN4S 393.689 g/mol |
| Benzodiazepines bind nonspecifically to benzodiazepine receptors BNZ1, which mediates sleep, and BNZ2, which affects affects muscle relaxation, anticonvulsant activity...more Number of Targets: 19 | |
T3D1791 | Broxyquinoline 521-74-4 | C9H5Br2NO 302.950 g/mol |
| Bromine is a powerful oxidizing agent and is able to release oxygen free radicals from the water in mucous membranes. These free radicals are also potent oxidizers and...more Number of Targets: 0 | |
T3D3075 | Brucine 357-57-3 | C23H26N2O4 394.464 g/mol |
| Brucine acts as an antagonist at the inhibitory or strychnine-sensitive glycine receptor, a ligand-gated chloride channel in the spinal cord and the brain. (L1230) Number of Targets: 9 | |
T3D2534 | Bufotenin 487-93-4 | C12H16N2O 204.268 g/mol |
| Bufotenin is a neurotoxin similar to the mushroom toxin psilocin. Thus it likely acts as a partial agonist at the 5-HT2A serotonin receptor in the brain where it mimic...more Number of Targets: 4 | |
T3D2742 | Bupivacaine 2180-92-9 | C18H28N2O 288.428 g/mol |
| Bupivacaine is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholinest...more Number of Targets: 2 | |
T3D2932 | Buprenorphine 52485-79-7 | C29H41NO4 467.640 g/mol |
| Buprenorphine's analgesic effect is due to partial agonist activity at mu-opioid receptors. Buprenorphine is also a kappa-opioid receptor antagonist. The partial agoni...more Number of Targets: 4 | |
T3D3802 | Buprofezin 69327-76-0 | C16H23N3OS 305.438 g/mol |
| Not Available Number of Targets: 13 | |
T3D2999 | Bupropion 34841-39-9 | C13H18ClNO 239.741 g/mol |
| Bupropion selectively inhibits the neuronal reuptake of dopamine, norepinephrine, and serotonin; actions on dopaminergic systems are more significant than imipramine o...more Number of Targets: 14 | |
T3D2807 | Buspirone 36505-84-7 | C21H31N5O2 385.503 g/mol |
| Buspirone binds to 5-HT type 1A serotonin receptors on presynaptic neurons in the dorsal raphe and on postsynaptic neurons in the hippocampus, thus inhibiting the firi...more Number of Targets: 10 | |
T3D4750 | Busulfan 55-98-1 | C6H14O6S2 246.302 g/mol |
| Busulfan is an alkylating agent that contains 2 labile methanesulfonate groups attached to opposite ends of a 4-carbon alkyl chain. Once busulfan is hydrolyzed, the me...more Number of Targets: 2 | |
T3D2721 | Butabarbital 125-40-6 | C10H16N2O3 212.246 g/mol |
| Butabarbital binds at a distinct binding site associated with a Cl- ionopore at the GABAA receptor, increasing the duration of time for which the Cl- ionopore is open....more Number of Targets: 6 | |
T3D0936 | Butacarb 2655-19-8 | C16H25NO2 263.375 g/mol |
| Butacarb is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoylation of the active sites o...more Number of Targets: 2 | |
T3D1087 | Butachlor 23184-66-9 | C17H26ClNO2 311.847 g/mol |
| Binds to nAChRs in nervous systems. Also causes endocrine disruption in humans by binding to and inhibiting the estrogen receptor. (T10, A590) Number of Targets: 35 | |
T3D3803 | Butafenacil 134605-64-4 | C20H18ClF3N2O6 474.815 g/mol |
| Not Available Number of Targets: 16 | |
T3D4589 | Butanone 78-93-3 | C4H8O 72.106 g/mol |
| Not Available Number of Targets: 1 | |
T3D3753 | Butenolide 16275-44-8 | C6H7NO3 141.125 g/mol |
| Butenolide causes lipid peroxidation, disrupting the membrane lipid bilayer and causing damage to membrane protiens. It also induces production of reactive oxygen spec...more Number of Targets: 17 | |
T3D3038 | Butethal 77-28-1 | C10H16N2O3 212.246 g/mol |
| Butethal binds at a distinct binding site associated with a Cl- ionopore at the GABAA receptor, increasing the duration of time for which the Cl- ionopore is open. The...more Number of Targets: 10 | |
T3D0937 | Butocarboxim 34681-10-2 | C7H14N2O2S 190.263 g/mol |
| Butocarboxim is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoylation of the active sit...more Number of Targets: 2 | |
T3D2837 | Butorphanol 42408-82-2 | C21H29NO2 327.461 g/mol |
| The exact mechanism of action is unknown, but is believed to interact with an opiate receptor site in the CNS (probably in or associated with the limbic system). The o...more Number of Targets: 3 | |
T3D0938 | Butoxycarboxim 34681-23-7 | C7H14N2O4S 222.262 g/mol |
| Butoxycarboxim is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoylation of the active s...more Number of Targets: 2 | |
T3D4480 | Butralin 33629-47-9 | C14H21N3O4 295.334 g/mol |
| Not Available Number of Targets: 14 | |
T3D1695 | Butyl cyanoacrylate 6606-65-1 | C8H11NO2 153.178 g/mol |
| Organic nitriles decompose into cyanide ions both in vivo and in vitro. Consequently the primary mechanism of toxicity for organic nitriles is their production of toxi...more Number of Targets: 39 | |
T3D3639 | Butyl cyclohexyl phthalate 84-64-0 | C18H24O4 304.381 g/mol |
| Phthalate esters are endocrine disruptors. They decrease foetal testis testosterone production and reduce the expression of steroidogenic genes by decreasing mRNA expr...more Number of Targets: 0 |