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Displaying toxin 1276 - 1300 of 3678 in total
T3DB ID Name
CAS Number
Formula
Weight
StructureTypeMechanism of Toxicity
T3D1725Bronidox
30007-47-7
C4H6BrNO4
211.999 g/mol
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  • Bromide Compound
  • Inorganic Compound
  • Lachrymator
  • Organic Compound
  • Organobromide
  • Pesticide
  • Synthetic Compound
Bronidox likely acts as an oxidizing agent that leads to oxidation of free sulfhydryls in essential enzymes. One of the most probable protein targets is the TRPA1 ion...more
Number of Targets: 1
T3D1724Bronopol
52-51-7
C3H6BrNO4
199.988 g/mol
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  • Bromide Compound
  • Cosmetic Toxin
  • Household Toxin
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Organic Compound
  • Organobromide
  • Synthetic Compound
While Bronopol is not in itself a nitrosating agent, under conditions where it decomposes (alkaline solution and/or elevated temperatures) it can liberate nitrite and ...more
Number of Targets: 9
T3D4573Brotizolam
57801-81-7
C15H10BrClN4S
393.689 g/mol
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  • Bromide Compound
  • Drug
  • Organic Compound
  • Organobromide
  • Organochloride
  • Synthetic Compound
Benzodiazepines bind nonspecifically to benzodiazepine receptors BNZ1, which mediates sleep, and BNZ2, which affects affects muscle relaxation, anticonvulsant activity...more
Number of Targets: 19
T3D1791Broxyquinoline
521-74-4
C9H5Br2NO
302.950 g/mol
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  • Bromide Compound
  • Industrial/Workplace Toxin
  • Organic Compound
  • Organobromide
  • Synthetic Compound
Bromine is a powerful oxidizing agent and is able to release oxygen free radicals from the water in mucous membranes. These free radicals are also potent oxidizers and...more
Number of Targets: 0
T3D3075Brucine
357-57-3
C23H26N2O4
394.464 g/mol
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  • Amide
  • Amine
  • Ether
  • Natural Compound
  • Organic Compound
  • Plant Toxin
Brucine acts as an antagonist at the inhibitory or strychnine-sensitive glycine receptor, a ligand-gated chloride channel in the spinal cord and the brain. (L1230)
Number of Targets: 9
T3D2534Bufotenin
487-93-4
C12H16N2O
204.268 g/mol
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  • Amine
  • Animal Toxin
  • Frog/Toad Toxin
  • Fungal Toxin
  • Metabolite
  • Natural Compound
  • Organic Compound
Bufotenin is a neurotoxin similar to the mushroom toxin psilocin. Thus it likely acts as a partial agonist at the 5-HT2A serotonin receptor in the brain where it mimic...more
Number of Targets: 4
T3D2742Bupivacaine
2180-92-9
C18H28N2O
288.428 g/mol
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  • Amide
  • Amine
  • Anesthetic, Local
  • Drug
  • Metabolite
  • Organic Compound
  • Synthetic Compound
Bupivacaine is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholinest...more
Number of Targets: 2
T3D2932Buprenorphine
52485-79-7
C29H41NO4
467.640 g/mol
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  • Amine
  • Analgesic, Opioid
  • Drug
  • Ether
  • Metabolite
  • Narcotic
  • Narcotic Antagonist
  • Organic Compound
  • Synthetic Compound
Buprenorphine's analgesic effect is due to partial agonist activity at mu-opioid receptors. Buprenorphine is also a kappa-opioid receptor antagonist. The partial agoni...more
Number of Targets: 4
T3D3802Buprofezin
69327-76-0
C16H23N3OS
305.438 g/mol
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  • Amide
  • Amine
  • Ether
  • Insecticide
  • Organic Compound
  • Pesticide
  • Synthetic Compound
Not Available
Number of Targets: 13
T3D2999Bupropion
34841-39-9
C13H18ClNO
239.741 g/mol
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  • Amine
  • Antidepressant
  • Antidepressant, Second-Generation
  • Antidepressive Agent, Second-Generation
  • Dopamine Uptake Inhibitor
  • Drug
  • Ester
  • Food Toxin
  • Metabolite
  • Organic Compound
  • Organochloride
  • Synthetic Compound
Bupropion selectively inhibits the neuronal reuptake of dopamine, norepinephrine, and serotonin; actions on dopaminergic systems are more significant than imipramine o...more
Number of Targets: 14
T3D2807Buspirone
36505-84-7
C21H31N5O2
385.503 g/mol
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  • Amide
  • Amine
  • Anti-Anxiety Agent
  • Anxiolytic
  • Drug
  • Hypnotic and Sedative
  • Metabolite
  • Organic Compound
  • Serotonin Agonist
  • Serotonin Receptor Agonist
  • Synthetic Compound
Buspirone binds to 5-HT type 1A serotonin receptors on presynaptic neurons in the dorsal raphe and on postsynaptic neurons in the hippocampus, thus inhibiting the firi...more
Number of Targets: 10
T3D4750Busulfan
55-98-1
C6H14O6S2
246.302 g/mol
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  • Alkylating Agent
  • Antineoplastic Agent, Alkylating
  • Drug
  • Immunosuppressive Agent
  • Metabolite
  • Myeloablative Agonist
  • Organic Compound
  • Synthetic Compound
Busulfan is an alkylating agent that contains 2 labile methanesulfonate groups attached to opposite ends of a 4-carbon alkyl chain. Once busulfan is hydrolyzed, the me...more
Number of Targets: 2
T3D2721Butabarbital
125-40-6
C10H16N2O3
212.246 g/mol
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  • Amide
  • Amine
  • Anti-Anxiety Agent
  • Barbiturate
  • Drug
  • Hypnotic and Sedative
  • Metabolite
  • Organic Compound
  • Synthetic Compound
Butabarbital binds at a distinct binding site associated with a Cl- ionopore at the GABAA receptor, increasing the duration of time for which the Cl- ionopore is open....more
Number of Targets: 6
T3D0936Butacarb
2655-19-8
C16H25NO2
263.375 g/mol
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  • Amine
  • Carbamate
  • Ester
  • Organic Compound
  • Pesticide
  • Synthetic Compound
Butacarb is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoylation of the active sites o...more
Number of Targets: 2
T3D1087Butachlor
23184-66-9
C17H26ClNO2
311.847 g/mol
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  • Amide
  • Amine
  • Aromatic Hydrocarbon
  • Chloroacetanilide
  • Ether
  • Organic Compound
  • Organochloride
  • Pesticide
  • Synthetic Compound
Binds to nAChRs in nervous systems. Also causes endocrine disruption in humans by binding to and inhibiting the estrogen receptor. (T10, A590)
Number of Targets: 35
T3D3803Butafenacil
134605-64-4
C20H18ClF3N2O6
474.815 g/mol
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  • Amide
  • Ester
  • Ether
  • Herbicide
  • Organic Compound
  • Organochloride
  • Organofluoride
  • Pesticide
  • Synthetic Compound
Not Available
Number of Targets: 16
T3D4589Butanone
78-93-3
C4H8O
72.106 g/mol
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  • Food Toxin
  • Household Toxin
  • Lachrymator
  • Metabolite
  • Natural Compound
  • Organic Compound
  • Plant Toxin
  • Pollutant
Not Available
Number of Targets: 1
T3D3753Butenolide
16275-44-8
C6H7NO3
141.125 g/mol
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  • Amide
  • Amine
  • Ester
  • Ether
  • Fungal Toxin
  • Mycotoxin
  • Natural Compound
  • Organic Compound
Butenolide causes lipid peroxidation, disrupting the membrane lipid bilayer and causing damage to membrane protiens. It also induces production of reactive oxygen spec...more
Number of Targets: 17
T3D3038Butethal
77-28-1
C10H16N2O3
212.246 g/mol
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  • Amide
  • Amine
  • Anti-Anxiety Agent
  • Barbiturate
  • Drug
  • Hypnotic and Sedative
  • Metabolite
  • Organic Compound
  • Synthetic Compound
Butethal binds at a distinct binding site associated with a Cl- ionopore at the GABAA receptor, increasing the duration of time for which the Cl- ionopore is open. The...more
Number of Targets: 10
T3D0937Butocarboxim
34681-10-2
C7H14N2O2S
190.263 g/mol
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  • Carbamate
  • Ether
  • Organic Compound
  • Pesticide
  • Synthetic Compound
Butocarboxim is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoylation of the active sit...more
Number of Targets: 2
T3D2837Butorphanol
42408-82-2
C21H29NO2
327.461 g/mol
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  • Amine
  • Analgesic, Opioid
  • Antitussive Agent
  • Drug
  • Metabolite
  • Narcotic
  • Narcotic Antagonist
  • Organic Compound
  • Synthetic Compound
The exact mechanism of action is unknown, but is believed to interact with an opiate receptor site in the CNS (probably in or associated with the limbic system). The o...more
Number of Targets: 3
T3D0938Butoxycarboxim
34681-23-7
C7H14N2O4S
222.262 g/mol
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  • Amine
  • Carbamate
  • Ester
  • Ether
  • Organic Compound
  • Pesticide
  • Synthetic Compound
Butoxycarboxim is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoylation of the active s...more
Number of Targets: 2
T3D4480Butralin
33629-47-9
C14H21N3O4
295.334 g/mol
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  • Amine
  • Herbicide
  • Lachrymator
  • Organic Compound
  • Pesticide
  • Synthetic Compound
Not Available
Number of Targets: 14
T3D1695Butyl cyanoacrylate
6606-65-1
C8H11NO2
153.178 g/mol
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  • Cyanide Compound
  • Ether
  • Household Toxin
  • Industrial/Workplace Toxin
  • Nitrile
  • Organic Compound
  • Synthetic Compound
Organic nitriles decompose into cyanide ions both in vivo and in vitro. Consequently the primary mechanism of toxicity for organic nitriles is their production of toxi...more
Number of Targets: 39
T3D3639Butyl cyclohexyl phthalate
84-64-0
C18H24O4
304.381 g/mol
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  • Aromatic Hydrocarbon
  • Cosmetic Toxin
  • Ester
  • Ether
  • Food Toxin
  • Household Toxin
  • Industrial/Workplace Toxin
  • Organic Compound
  • Phthalate
  • Plasticizer
  • Synthetic Compound
Phthalate esters are endocrine disruptors. They decrease foetal testis testosterone production and reduce the expression of steroidogenic genes by decreasing mRNA expr...more
Number of Targets: 0
Displaying toxin 1276 - 1300 of 3678 in total