Browsing Toxins By Category
Displaying toxin 1151 - 1175 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D0006 | Benzene 71-43-2 | C6H6 78.112 g/mol |  |
| The toxic agents of benzene are its metabolites. Benzene is able increase its toxicity by inducing cytochrome P450 2E1, its main metabolic enzyme. Benzene's primary to...more Number of Targets: 101 |
| T3D1692 | Benzeneacetonitrile 140-29-4 | C8H7N 117.148 g/mol |  |
| Organic nitriles decompose into cyanide ions both in vivo and in vitro. Consequently the primary mechanism of toxicity for organic nitriles is their production of toxi...more Number of Targets: 39 |
| T3D0310 | Benzenearsonic acid 98-05-5 | C6H7AsO3 202.040 g/mol |  |
| Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co...more Number of Targets: 52 |
| T3D1817 | Benzeneselenol 645-96-5 | C6H6Se 157.070 g/mol |  |
| Selenium readily substitutes for sulfur in biomolecules and in many biochemical reactions, especially when the concentration of selenium is high and the concentration ...more Number of Targets: 0 |
| T3D0026 | Benzidine 92-87-5 | C12H12N2 184.237 g/mol |  |
| N-acetylated benzidine metabolites are believed to form adducts with nucleic acids. Carcinogenesis is initiated when they are activated by peroxidation by prostaglandi...more Number of Targets: 13 |
| T3D2980 | Benzocaine 94-09-7 | C9H11NO2 165.189 g/mol |  |
| Benzocaine binds to sodium channels and reversibly stabilizes the neuronal membrane which decreases its permeability to sodium ions. Depolarization of the neuronal mem...more Number of Targets: 3 |
| T3D0070 | Benzofluoranthene 56832-73-6 | C20H12 252.309 g/mol |  |
| The ability of PAH's to bind to blood proteins such as albumin allows them to be transported throughout the body. Many PAH's induce the expression of cytochrome P450 e...more Number of Targets: 3 |
| T3D4785 | Benzoic acid 65-85-0 | C7H6O2 122.121 g/mol |  |
| Not Available Number of Targets: 5 |
| T3D4906 | Benzoin 119-53-9 | C14H12O2 212.244 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D1691 | Benzonitrile 100-47-0 | C7H5N 103.121 g/mol |  |
| Organic nitriles decompose into cyanide ions both in vivo and in vitro. Consequently the primary mechanism of toxicity for organic nitriles is their production of toxi...more Number of Targets: 39 |
| T3D3976 | Benzophenone 119-61-9 | C13H10O 182.218 g/mol |  |
| Benzophenone is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholines...more Number of Targets: 7 |
| T3D5003 | Benzoquinoneacetic acid 10275-07-7 | C8H6O4 166.131 g/mol |  | Not Available | Not Available Number of Targets: 0 |
| T3D0039 | Benzo[a]anthracene 56-55-3 | C18H12 228.288 g/mol |  |
| The ability of PAH's to bind to blood proteins such as albumin allows them to be transported throughout the body. Many PAH's induce the expression of cytochrome P450 e...more Number of Targets: 7 |
| T3D0009 | Benzo[a]pyrene 50-32-8 | C20H12 252.309 g/mol |  |
| The ability of PAH's to bind to blood proteins such as albumin allows them to be transported throughout the body. Many PAH's induce the expression of cytochrome P450 e...more Number of Targets: 9 |
| T3D0010 | Benzo[b]fluoranthene 205-99-2 | C20H12 252.309 g/mol |  |
| The ability of PAH's to bind to blood proteins such as albumin allows them to be transported throughout the body. Many PAH's induce the expression of cytochrome P450 e...more Number of Targets: 5 |
| T3D0226 | Benzo[e]pyrene 192-97-2 | C20H12 252.309 g/mol |  |
| The ability of PAH's to bind to blood proteins such as albumin allows them to be transported throughout the body. Many PAH's induce the expression of cytochrome P450 e...more Number of Targets: 3 |
| T3D0621 | Benzo[ghi]perylene 191-24-2 | C22H12 276.331 g/mol |  |
| The ability of PAH's to bind to blood proteins such as albumin allows them to be transported throughout the body. Many PAH's induce the expression of cytochrome P450 e...more Number of Targets: 3 |
| T3D0622 | Benzo[j]fluoranthene 205-82-3 | C20H12 252.309 g/mol |  |
| The ability of PAH's to bind to blood proteins such as albumin allows them to be transported throughout the body. Many PAH's induce the expression of cytochrome P450 e...more Number of Targets: 3 |
| T3D0062 | Benzo[k]fluoranthene 207-08-9 | C20H12 252.309 g/mol |  |
| The ability of PAH's to bind to blood proteins such as albumin allows them to be transported throughout the body. Many PAH's induce the expression of cytochrome P450 e...more Number of Targets: 3 |
| T3D2919 | Benzphetamine 156-08-1 | C17H21N 239.355 g/mol |  |
| Although the mechanism of action of the sympathomimetic appetite suppressants in the treatment of obesity is not fully known, these medications have pharmacological ef...more Number of Targets: 5 |
| T3D2825 | Benzthiazide 91-33-8 | C15H14ClN3O4S3 431.937 g/mol |  |
| As a diuretic, benzthiazide inhibits active chloride reabsorption at the early distal tubule via the Na-Cl cotransporter, resulting in an increase in the excretion of ...more Number of Targets: 7 |
| T3D3214 | Benzyl acetate 140-11-4 | C9H10O2 150.175 g/mol |  |
| Benzyl acetate is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholin...more Number of Targets: 1 |
| T3D1776 | Benzyl bromide 100-39-0 | C7H7Br 171.034 g/mol |  |
| Bromine is a powerful oxidizing agent and is able to release oxygen free radicals from the water in mucous membranes. These free radicals are also potent oxidizers and...more Number of Targets: 1 |
| T3D0195 | Benzyl butyl phthalate 85-68-7 | C19H20O4 312.360 g/mol |  |
| Phthalate esters are endocrine disruptors. They decrease foetal testis testosterone production and reduce the expression of steroidogenic genes by decreasing mRNA expr...more Number of Targets: 11 |
| T3D4897 | Benzyl cinnamate 103-41-3 | C16H14O2 238.281 g/mol |  |
| Not Available Number of Targets: 1 |