Browsing Toxins By Category
Displaying toxin 1076 - 1100 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D1302 | Arsole 287-77-4 | C4H5As 128.004 g/mol |  |
| Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co...more Number of Targets: 44 |
| T3D4912 | Ascorbyl palmitate 137-66-6 | C22H38O7 414.533 g/mol |  |
| Not Available Number of Targets: 2 |
| T3D2936 | Aspirin 50-78-2 | C9H8O4 180.157 g/mol |  |
| The analgesic, antipyretic, and anti-inflammatory effects of acetylsalicylic acid are due to actions by both the acetyl and the salicylate portions of the intact molec...more Number of Targets: 18 |
| T3D3749 | Asteltoxin 79663-49-3 | C23H30O7 418.480 g/mol |  |
| Asteltoxin inhibits mitochondrial respiration by affecting its energy transfer system. It does this by inhibiting Mg2+ and Na+/K+-ATPases. (A3002, A3003, A3031) Number of Targets: 8 |
| T3D2844 | Astemizole 68844-77-9 | C28H31FN4O 458.570 g/mol |  |
| Astemizole competes with histamine for binding at H1-receptor sites in the GI tract, uterus, large blood vessels, and bronchial muscle. This reversible binding of aste...more Number of Targets: 15 |
| T3D0923 | Asulam 3337-71-1 | C8H10N2O4S 230.241 g/mol |  |
| Asulam is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholinesterase...more Number of Targets: 6 |
| T3D0924 | Asulam, sodium salt 2302-17-2 | C8H10N2NaO4S 253.231 g/mol |  |
| Asulam, sodium salt is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylc...more Number of Targets: 2 |
| T3D4171 | Asymmetric dimethylarginine 30315-93-6 | C8H18N4O2 202.254 g/mol |  |
| Uremic toxins such as asymmetric dimethylarginine are actively transported into the kidneys via organic ion transporters (especially OAT3). Increased levels of uremic ...more Number of Targets: 5 |
| T3D3480 | Atenolol 29122-68-7 | C14H22N2O3 266.336 g/mol |  |
| Like metoprolol, atenolol competes with sympathomimetic neurotransmitters such as catecholamines for binding at beta(1)-adrenergic receptors in the heart and vascular ...more Number of Targets: 2 |
| T3D2737 | Atomoxetine 82248-59-7 | C17H21NO 255.355 g/mol |  |
| The precise mechanism by which atomoxetine produces its therapeutic effects in Attention-Deficit/Hyperactivity Disorder (ADHD) is unknown, but is thought to be related...more Number of Targets: 6 |
| T3D4980 | Atorvastatin 134523-00-5 | C33H34FN2O5 557.632 g/mol |  |
| Atorvastatin selectively and competitively inhibits the hepatic enzyme HMG-CoA reductase. As HMG-CoA reductase is responsible for converting HMG-CoA to mevalonate in t...more Number of Targets: 3 |
| T3D2495 | Atracotoxin, omega- (Hadronyche versuta) 193981-10-1 | Not Available 4055.410 g/mol |  |
| omega-Atracotoxins inhibit invertebrate voltage-gated calcium channel currents. (T170, L1812) Number of Targets: 0 |
| T3D4477 | Atrazine 1912-24-9 | C8H14ClN5 215.683 g/mol |  |
| Not Available Number of Targets: 15 |
| T3D3750 | Aurovertin B 55350-03-3 | C25H32O8 460.517 g/mol |  |
| Aurovertins are a mixed, noncompetitive inhibitors of both ATP hydrolysis and synthesis. They do this by inhibiting the proton-pumping F1F0-ATP synthase by binding to ...more Number of Targets: 3 |
| T3D3751 | Aurovertin D 65256-31-7 | C25H32O9 476.516 g/mol |  |
| Aurovertins are a mixed, noncompetitive inhibitors of both ATP hydrolysis and synthesis. They do this by inhibiting the proton-pumping F1F0-ATP synthase by binding to ...more Number of Targets: 1 |
| T3D1041 | Avermectin B1a 65195-55-3 | C48H72O14 873.077 g/mol |  |
| It has low solubility in water and extensive non-specific binding. It opens GABA-insensitive chloride channels, reducing membrane resistance and increasing conductance...more Number of Targets: 11 |
| T3D1042 | Avermectin B1b 65195-56-4 | C47H70O14 859.050 g/mol |  |
| It has low solubility in water and extensive non-specific binding. It opens GABA-insensitive chloride channels, reducing membrane resistance and increasing conductance...more Number of Targets: 11 |
| T3D4676 | Azacitidine 320-67-2 | C8H12N4O5 244.205 g/mol |  |
| Azacitidine (5-azacytidine) is a chemical analogue of the cytosine nucleoside used in DNA and RNA. Azacitidine is thought to induce antineoplastic activity via two mec...more Number of Targets: 3 |
| T3D3794 | Azamethiphos 35575-96-3 | C9H10ClN2O5PS 324.678 g/mol |  |
| Azamethiphos is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholines...more Number of Targets: 11 |
| T3D2672 | Azaspiracid 214899-21-5 | C47H71NO12 842.066 g/mol |  |
| Azaspiracid-4 dose-dependent inhibits the increase in cytosolic Ca2+ levels induced by thapsigargin (Tg) (A330). Azaspiracid-2 and Azaspiracid-3 clearly increase cytos...more Number of Targets: 1 |
| T3D4677 | Azathioprine 446-86-6 | C9H7N7O2S 277.263 g/mol |  |
| Azathioprine antagonizes purine metabolism and may inhibit synthesis of DNA, RNA, and proteins. It may also interfere with cellular metabolism and inhibit mitosis. Its...more Number of Targets: 1 |
| T3D4799 | Azelaic Acid 123-99-9 | C9H16O4 188.221 g/mol |  |
| The exact mechanism of action of azelaic acid is not known. It is thought that azelaic acid manifests its antibacterial effects by inhibiting the synthesis of cellular...more Number of Targets: 4 |
| T3D4558 | Azelastine 58581-89-8 | C22H24ClN3O 381.898 g/mol |  |
| Azelastine competes with histamine for the H1-receptor sites on effector cells and acts as an antagonist by inhibiting the release of histamine and other mediators inv...more Number of Targets: 7 |
| T3D1285 | Azocyclotin 41083-11-8 | C20H35N3Sn 436.220 g/mol |  |
| Organotin compounds produce neurotoxic and immunotoxic effects. Organotins may directly activate glial cells contributing to neuronal cell degeneration by local releas...more Number of Targets: 12 |
| T3D3795 | Azoxystrobin 131860-33-8 | C22H17N3O5 403.388 g/mol |  |
| Organic nitriles decompose into cyanide ions both in vivo and in vitro. Consequently the primary mechanism of toxicity for organic nitriles is their production of toxi...more Number of Targets: 17 |