Browsing Toxins By Category
Displaying toxin 776 - 800 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D2306 | 4-Bromo-2,3,7,8-tetrachlorodibenzofuran 115656-08-1 | C12H3BrCl4O 384.868 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2036 | 4-Bromobiphenyl Ether 101-55-3 | C12H9BrO 249.103 g/mol |  |
| Like other halogenated aromatic hydrocarbons, polybrominated diphenyl ethers bind to the cellular aryl hydrocarbon receptor (AhR), which regulates the synthesis of a v...more Number of Targets: 6 |
| T3D0392 | 4-Chlorobiphenyl 2051-62-9 | C12H9Cl 188.653 g/mol |  |
| The mechanism of action varies with the specific PCB. Dioxin-like PCBs bind to the aryl hydrocarbon receptor, which disrupts cell function by altering the transcriptio...more Number of Targets: 8 |
| T3D2307 | 4-Chlorodibenzofuran 74992-96-4 | C12H7ClO 202.636 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D0868 | 4-Chlorophenol 106-48-9 | C6H5ClO 128.556 g/mol |  |
| 4-chlorophenol works as a weak uncoupler of oxidative phosphorylation and inhibitors of cellular respiration. The ability of chlorophenols to uncouple oxidative phosph...more Number of Targets: 3 |
| T3D0910 | 4-Chlorophenyl-N-methylcarbamate 2620-53-3 | C8H8ClNO2 185.608 g/mol |  |
| 4-Chlorophenyl-N-methylcarbamate is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoylati...more Number of Targets: 2 |
| T3D4191 | 4-Decenal 30390-50-2 | C10H18O 154.249 g/mol |  |
| Uremic toxins such as 4-Decenal are actively transported into the kidneys via organic ion transporters (especially OAT3). Increased levels of uremic toxins can stimula...more Number of Targets: 3 |
| T3D3201 | 4-Ethylphenol 123-07-9 | C8H10O 122.164 g/mol |  |
| Metabolized to 1- and 2- phenylethanol (A622). Number of Targets: 2 |
| T3D0911 | 4-Ethylthiophenyl methylcarbamate 18809-57-9 | C10H13NO2S 211.281 g/mol |  |
| 4-Ethylthiophenyl methylcarbamate is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoylat...more Number of Targets: 2 |
| T3D4269 | 4-Hydroxybutyric acid 591-81-1 | C4H8O3 104.105 g/mol |  |
| GHB reaches much higher concentrations in the brain and activates GABAB receptors, which are primarily responsible for its sedative effects. GHB receptors are densely ...more Number of Targets: 2 |
| T3D4193 | 4-Hydroxydecenal 73529-64-3 | C10H18O2 170.249 g/mol |  |
| Uremic toxins such as 4-Hydroxydecenal are actively transported into the kidneys via organic ion transporters (especially OAT3). Increased levels of uremic toxins can ...more Number of Targets: 3 |
| T3D4194 | 4-Hydroxyhexanal 109710-36-3 | C6H10O2 114.142 g/mol |  |
| Uremic toxins such as 4-Hydroxyhexenall are actively transported into the kidneys via organic ion transporters (especially OAT3). Increased levels of uremic toxins can...more Number of Targets: 3 |
| T3D4180 | 4-Hydroxynonenal 75899-68-2 | C9H16O2 156.222 g/mol |  |
| Uremic toxins such as 4-Hydroxynonenal are actively transported into the kidneys via organic ion transporters (especially OAT3). Increased levels of uremic toxins can ...more Number of Targets: 16 |
| T3D4195 | 4-Hydroxyoctenal 17449-15-9 | C8H14O2 142.196 g/mol |  |
| Uremic toxins such as 4-Hydroxyoctenal are actively transported into the kidneys via organic ion transporters (especially OAT3). Increased levels of uremic toxins can ...more Number of Targets: 3 |
| T3D4413 | 4-Hydroxyproline 51-35-4 | C5H9NO3 131.130 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D4937 | 4-Hydroxytamoxifen 68047-06-3 | C26H29NO2 387.514 g/mol |  |
| Not Available Number of Targets: 22 |
| T3D4894 | 4-Methyl-3-penten-2-one, 9CI 141-79-7 | C6H10O 98.143 g/mol |  |
| Not Available Number of Targets: 2 |
| T3D0912 | 4-Methylformamido-3,5-xylyl methylcarbamate 10233-94-0 | C12H16N2O3 236.267 g/mol |  |
| 4-Methylformamido-3,5-xylyl methylcarbamate is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by c...more Number of Targets: 2 |
| T3D3443 | 4-Methylheptane 589-53-7 | C8H18 114.229 g/mol |  |
| Petroleum distillates are central nervous system depressants and cause pulmonary damage. (A600) Number of Targets: 0 |
| T3D2018 | 4-Monobromobiphenyl 92-66-0 | C12H9Br 233.104 g/mol |  |
| The exact mechanism of toxicty of PBBs varies depending on the specific congener. The predominant interaction is believed to involve the aryl hydrocarbon receptor (AhR...more Number of Targets: 1 |
| T3D0257 | 4-Nitrophenol 100-02-7 | C6H5NO3 139.109 g/mol |  |
| The nitrite in nitrophenols causes the autocatalytic oxidation of oxyhemoglobin to hydrogen peroxide and methemoglobin. This elevation of methemoglobin levels is a con...more Number of Targets: 12 |
| T3D4836 | 4-Nonylphenol 104-40-5 | C15H24O 220.351 g/mol |  |
| Not Available Number of Targets: 7 |
| T3D3949 | 4-Phenylphenol 92-69-3 | C12H10O 170.207 g/mol |  |
| Not Available Number of Targets: 8 |
| T3D4881 | 4-tert-Butylphenol 98-54-4 | C10H14O 150.218 g/mol |  |
| 4-Tert-butylphenol is structurally similar to the melanin precursor tyrosine, and acts as a substrate for tyrosinase. Tyrosinase oxidizes 4-tert-butylphenol to a quino...more Number of Targets: 3 |
| T3D4933 | 4-tert-Butylphenyl salicylate 87-18-3 | C17H18O3 270.323 g/mol |  |
| Not Available Number of Targets: 2 |