Browsing Toxins By Category
Displaying toxin 2726 - 2750 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D4745 | Norethindrone 68-22-4 | C20H26O2 298.419 g/mol |  |
| Progestins diffuse freely into target cells and bind to the progesterone receptor. Target cells include the female reproductive tract, the mammary gland, the hypothala...more Number of Targets: 6 |
| T3D3893 | Norflurazon 27314-13-2 | C12H9ClF3N3O 303.668 g/mol |  |
| Not Available Number of Targets: 13 |
| T3D2818 | Nortriptyline 72-69-5 | C19H21N 263.377 g/mol |  |
| It is believed that nortriptyline either inhibits the reuptake of the neurotransmitter serotonin at the neuronal membrane or acts at beta-adrenergic receptors. Tricycl...more Number of Targets: 24 |
| T3D2638 | Notexin 37233-96-4 | Not Available 13593.310 g/mol |  |
| Notexin is myotoxic and inhibits neuromuscular transmission by blocking acetylcholine release from the nerve termini. (T170) Number of Targets: 0 |
| T3D4521 | Novaluron 116714-46-6 | C17H9ClF8N2O4 492.705 g/mol |  |
| Not Available Number of Targets: 6 |
| T3D2522 | Noxiustoxin 85205-49-8 | Not Available 4201.920 g/mol |  |
| Noxiustoxin blocks voltage-gated non-inactivating potassium channels and unblocks inactivating potassium channels blocked by alpha-dendrotoxin in synaptosomes. It also...more Number of Targets: 23 |
| T3D2847 | Nystatin 1400-61-9 | C47H75NO17 926.095 g/mol |  |
| Nystatin interacts with 14-α demethylase, a cytochrome P-450 enzyme necessary for the conversion of lanosterol to ergosterol. This results in inhibition of ergosterol ...more Number of Targets: 0 |
| T3D1468 | Nysted reagent 41114-59-4 | C6H12Br2OZn3 456.194 g/mol |  |
| Anaemia results from the excessive absorption of zinc suppressing copper and iron absorption, most likely through competitive binding of intestinal mucosal cells. Unba...more Number of Targets: 1 |
| T3D0151 | O,P'-DDD 53-19-0 | C14H10Cl4 320.041 g/mol |  |
| DDD toxicity occurs via at least four mechanisms, possibly all functioning simultaneously. DDD reduces potassium transport across the membrane. DDD inhibits the inacti...more Number of Targets: 43 |
| T3D0050 | O,P'-DDT 789-02-6 | C14H9Cl5 354.486 g/mol |  |
| DDT toxicity occurs via at least four mechanisms, possibly all functioning simultaneously. DDT reduces potassium transport across the membrane. DDT inhibits inactivati...more Number of Targets: 60 |
| T3D0990 | o-(2-Propynyloxy)phenyl methylcarbamate 3279-46-7 | C11H11NO3 205.210 g/mol |  |
| o-(2-Propynyloxy)phenyl methylcarbamate is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carba...more Number of Targets: 2 |
| T3D0196 | o-Cresol 95-48-7 | C7H8O 108.138 g/mol |  |
| Target organs of ingested cresols in humans are the blood, kidneys, lungs, liver, heart, and central nervous system. Cresols impair the stratum corneum and produce coa...more Number of Targets: 3 |
| T3D3965 | O-Desmethylangolensin 21255-69-6 | C15H14O4 258.269 g/mol |  |
| O-desmethylangolensin (ODMA) exerts androgen receptor antagonistic activity and agonistic activity towards estrogen receptor (ER)-α and ERβ. The structure of ODMA is s...more Number of Targets: 2 |
| T3D4217 | O-Toluidine 95-53-4 | C7H9N 107.153 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D0864 | o-Xylene 95-47-6 | C8H10 106.165 g/mol |  |
| o-Xylene is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholinestera...more Number of Targets: 4 |
| T3D1807 | o-Xylyl bromide 89-92-9 | C8H9Br 185.061 g/mol |  |
| Organobromide compounds such as o-Xylyl bromide are strong alkylating agents. Consequently they can readily modify free thiols (cysteines) and methionine residues of ...more Number of Targets: 1 |
| T3D3605 | Ochratoxin A 303-47-9 | C20H18ClNO6 403.813 g/mol |  |
| Ochratoxin A has been shown to be weakly mutagenic, possibly by induction of oxidative DNA damage. The nephrotoxin ochratoxin A (OTA) causes a reduction of glomerular ...more Number of Targets: 5 |
| T3D3606 | Ochratoxin B 4825-86-9 | C20H19NO6 369.368 g/mol |  |
| Ochratoxin B is thought to inhibit the accumulation of cartilage proteoglycans and general protein synthesis in a concentration-related manner. (A2872) Number of Targets: 0 |
| T3D3607 | Ochratoxin C 4865-85-4 | C22H22ClNO6 431.866 g/mol |  |
| Ochratoxin A, a metabolite of Ochratoxin C, has been shown to be weakly mutagenic, possibly by induction of oxidative DNA damage. The nephrotoxin ochratoxin A (OTA) ca...more Number of Targets: 3 |
| T3D1948 | Octabromobiphenyl 27858-07-7 | C12H2Br8 785.376 g/mol |  |
| The exact mechanism of toxicty of PBBs varies depending on the specific congener. The predominant interaction is believed to involve the aryl hydrocarbon receptor (AhR...more Number of Targets: 1 |
| T3D2118 | Octachlorodibenzo-p-dioxin 3268-87-9 | C12Cl8O2 459.751 g/mol |  |
| CDDs cause their toxic effects by binding to the aryl hydrocarbon receptor and subsequently altering the trascription of certain genes. The affinity for the Ah recepto...more Number of Targets: 4 |
| T3D3440 | Octane 111-65-9 | C8H18 114.229 g/mol |  |
| Petroleum distillates are central nervous system depressants and cause pulmonary damage. (A600) Number of Targets: 2 |
| T3D1706 | Octyl cyanoacrylate 6701-17-3 | C12H19NO2 209.285 g/mol |  |
| Organic nitriles decompose into cyanide ions both in vivo and in vitro. Consequently the primary mechanism of toxicity for organic nitriles is their production of toxi...more Number of Targets: 39 |
| T3D4831 | Octyl gallate 1034-01-1 | C15H22O5 282.332 g/mol |  |
| Not Available Number of Targets: 16 |
| T3D3083 | Oenanthotoxin 20311-78-8 | C17H22O2 258.355 g/mol |  |
| Oenanthotoxin is a central nervous system poison and acts as a non-competitive gamma-aminobutyric acid antagonist. (L1243) Number of Targets: 19 |