Browsing Toxins By Category
Displaying toxin 2701 - 2725 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D1264 | Niobium tin 12035-04-0 | Nb3Sn 397.430 g/mol |  |
| Inorganic and organic tin compounds are weak inhibitors of alcohol dehydrogenase. (A183) Number of Targets: 7 |
| T3D1742 | Niobium(V) bromide 13748-45-0 | Br5H4Nb 496.458 g/mol |  |
| Bromine is a powerful oxidizing agent and is able to release oxygen free radicals from the water in mucous membranes. These free radicals are also potent oxidizers and...more Number of Targets: 6 |
| T3D0315 | Nitarsone 98-72-6 | C6H6AsNO5 247.037 g/mol |  |
| Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co...more Number of Targets: 44 |
| T3D3892 | Nitrapyrin 1929-82-4 | C6H3Cl4N 230.907 g/mol |  |
| Not Available Number of Targets: 5 |
| T3D0216 | Nitrate 14797-55-8 | NO3 62.005 g/mol |  |
| Nitrate's toxicity is a result of it's conversion to nitrite once in the body. Nitrite causes the autocatalytic oxidation of oxyhemoglobin to hydrogen peroxide and met...more Number of Targets: 16 |
| T3D3057 | Nitrazepam 146-22-5 | C15H11N3O3 281.266 g/mol |  |
| Nitrazepam belongs to a group of medicines called benzodiazepines. It acts on benzodiazepine receptors in the brain which are associated with the GABA receptors causin...more Number of Targets: 24 |
| T3D3571 | Nitric acid 7697-37-2 | HNO3 63.013 g/mol |  |
| Nitric acid is a corrosive acid and a powerful oxidizing agent. The major hazard posed by it is chemical burns as it carries out acid hydrolysis with proteins (amide) ...more Number of Targets: 16 |
| T3D0989 | Nitrilacarb 29672-19-3 | C9H15N3O2 197.234 g/mol |  |
| Nitrilacarb is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoylation of the active site...more Number of Targets: 2 |
| T3D4705 | Nitrilotriacetic Acid 139-13-9 | C6H9NO6 191.139 g/mol |  |
| Not Available Number of Targets: 2 |
| T3D0212 | Nitrite 14797-65-0 | NO2 46.006 g/mol |  |
| Nitrite causes the autocatalytic oxidation of oxyhemoglobin to hydrogen peroxide and methemoglobin. This elevation of methemoglobin levels is a condition known as meth...more Number of Targets: 9 |
| T3D1050 | Nitro-methylene-cyclopentane 27861-40-1 | C6H9NO2 127.141 g/mol |  |
| Acts as a neurotransmitter mimic , having both excitatory and depressant effects, eventually blocking postsynaptic nicotinic receptors. (T10) Number of Targets: 5 |
| T3D4216 | Nitrobenzene 98-95-3 | C6H5NO2 123.109 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D4752 | Nitrofural 59-87-0 | C6H6N4O4 198.136 g/mol |  |
| The exact mechanism of action is unknown. Nitrofurazone inhibits several bacterial enzymes, especially those involved in the aerobic and anaerobic degradation of gluco...more Number of Targets: 1 |
| T3D2679 | Nitrofurantoin 67-20-9 | C8H6N4O5 238.157 g/mol |  |
| Nitrofurantoin is activated by bacterial flavoproteins (nitrofuran reductase) to active reduced reactive intermediates that are thought to modulate and damage ribosoma...more Number of Targets: 4 |
| T3D1743 | Nitrogen tribromide 15162-90-0 | Br3N 253.719 g/mol |  |
| Bromine is a powerful oxidizing agent and is able to release oxygen free radicals from the water in mucous membranes. These free radicals are also potent oxidizers and...more Number of Targets: 6 |
| T3D1052 | Nitromethylidenecyclohexane 27861-39-8 | C7H11NO2 141.168 g/mol |  |
| Acts as a neurotransmitter mimic , having both excitatory and depressant effects, eventually blocking postsynaptic nicotinic receptors. (T10) Number of Targets: 5 |
| T3D1875 | Nitronium hexafluoroantimonate(V) 17856-92-7 | F6NO2Sb 281.760 g/mol |  |
| The inhalation data suggests that the myocardium is a target of antimony toxicity. It is possible that antimony affects circulating glucose by interfering with enzymes...more Number of Targets: 20 |
| T3D1876 | Nitrosonium (nitrosyl) hexafluoroantimonate 16941-06-3 | F6NOSb 265.760 g/mol |  |
| The inhalation data suggests that the myocardium is a target of antimony toxicity. It is possible that antimony affects circulating glucose by interfering with enzymes...more Number of Targets: 20 |
| T3D3549 | Nitrous acid 7782-77-6 | HNO2 47.013 g/mol |  |
| Nitrite causes the autocatalytic oxidation of oxyhemoglobin to hydrogen peroxide and methemoglobin. This elevation of methemoglobin levels is a condition known as meth...more Number of Targets: 9 |
| T3D3674 | Nivalenol 23282-20-4 | C15H20O7 312.315 g/mol |  |
| Unlike many other mycotoxins, trichothecenes do not require metabolic activation to exert their biological activity, instead directly reacting with cellular components...more Number of Targets: 2 |
| T3D3616 | Nodularin-R 118399-22-7 | C41H60N8O10 824.963 g/mol |  |
| The site of action of microcystins is the hepatocyte, the commonest cell type in the liver. They act by disrupting the cytoskeleton, the adaptable protein framework th...more Number of Targets: 23 |
| T3D2044 | Nonabromobiphenyl Ether 63936-56-1 | C12HBr9O 880.272 g/mol |  |
| Like other halogenated aromatic hydrocarbons, polybrominated diphenyl ethers bind to the cellular aryl hydrocarbon receptor (AhR), which regulates the synthesis of a v...more Number of Targets: 6 |
| T3D4192 | Nonanal 124-19-6 | C9H18O 142.239 g/mol |  |
| Uremic toxins such as nonanal are actively transported into the kidneys via organic ion transporters (especially OAT3). Increased levels of uremic toxins can stimulate...more Number of Targets: 3 |
| T3D4588 | Nordiazepam 1088-11-5 | C15H11ClN2O 270.714 g/mol |  |
| Benzodiazepines bind nonspecifically to benzodiazepine receptors BNZ1, which mediates sleep, and BNZ2, which affects affects muscle relaxation, anticonvulsant activity...more Number of Targets: 18 |
| T3D4154 | Norepinephrine 51-41-2 | C8H11NO3 169.178 g/mol |  |
| Uremic toxins such as noradrenalin are actively transported into the kidneys via organic ion transporters (especially OAT3). Increased levels of uremic toxins can stim...more Number of Targets: 19 |