Browsing Toxins By Category
Displaying toxin 2651 - 2675 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D2855 | Nafarelin 76932-56-4 | C66H83N17O13 1322.471 g/mol |  |
| Like GnRH, initial or intermittent administration of nafarelin stimulates release of the gonadotropins luteinizing hormone (LH) and follicle-stimulating hormone (FSH) ...more Number of Targets: 2 |
| T3D2474 | Naftidrofuryl 31329-57-4 | C24H33NO3 383.524 g/mol |  |
| Naftidrofuryl blocks the type 2 serotonin (5-HT2) receptors and thereby inhibits the effects of serotonin-induced vasoconstriction
or platelet aggregation. It is also ...more Number of Targets: 3 |
| T3D2911 | Nalbuphine 20594-83-6 | C21H27NO4 357.443 g/mol |  |
| Receptor studies show that nalbuphine exerts its action via binding to mu, kappa, and delta receptors, but not to sigma receptors. Nalbuphine is primarily a kappa agon...more Number of Targets: 3 |
| T3D2864 | Naltrexone 16590-41-3 | C20H23NO4 341.401 g/mol |  |
| Naltrexone is a pure opiate antagonist and has little or no agonist activity. The mechanism of action of naltrexone in alcoholism is not understood; however, involveme...more Number of Targets: 7 |
| T3D4103 | Nantenine 2565-01-7 | C20H21NO4 339.385 g/mol |  |
| Nantenine is an antagonist at both the α1 adrenergic receptor and the 5-HT2A serotonin receptor, and blocks both the behavioural and physiological effects of MDMA in a...more Number of Targets: 37 |
| T3D0078 | Naphthalene 91-20-3 | C10H8 128.171 g/mol |  |
| PAH's such as naphthalene are transported throughout the body after binding blood proteins such as albumin. Binding to the aryl hydrocarbon receptor or glycine N-methy...more Number of Targets: 12 |
| T3D3890 | Napropamide 15299-99-7 | C17H21NO2 271.354 g/mol |  |
| Not Available Number of Targets: 26 |
| T3D2939 | Naratriptan 121679-13-8 | C17H25N3O2S 335.464 g/mol |  |
| Three distinct pharmacological actions have been implicated in the antimigraine effect of the triptans: (1) stimulation of presynaptic 5-HT1D receptors, which serves t...more Number of Targets: 4 |
| T3D2995 | Nefazodone 83366-66-9 | C25H32ClN5O2 470.007 g/mol |  |
| Within the serotonergic system, nefazodone acts as an antagonist at type 2 serotonin (5-HT2) post-synaptic receptors and, like fluoxetine-type antidepressants, inhibit...more Number of Targets: 14 |
| T3D2951 | Neomycin 1404-04-2 | C23H46N6O13 614.644 g/mol |  |
| Aminoglycosides like neomycin "irreversibly" bind to specific 30S-subunit proteins and 16S rRNA. Specifically neomycin binds to four nucleotides of 16S rRNA and a sing...more Number of Targets: 3 |
| T3D3430 | Neopentane 463-82-1 | C5H12 72.149 g/mol |  |
| Pentane is a central nervous system depressant. It affects the peripheral nervous system through demyelinization and axonal degeneration. (T29) Number of Targets: 0 |
| T3D4162 | Neopterin 2009-64-5 | C9H11N5O4 253.215 g/mol |  |
| Uremic toxins such as neopterin are actively transported into the kidneys via organic ion transporters (especially OAT3). Increased levels of uremic toxins can stimula...more Number of Targets: 3 |
| T3D4023 | Neosaxitoxin 64296-20-4 | C10H17N7O5 315.286 g/mol |  |
| Neosaxitoxin (NSTX) blocks the extracellular portion, the outer vestibule, of some voltage gated sodium channels in a very powerful and reversible manner, without affe...more Number of Targets: 0 |
| T3D3708 | Neosolaniol 36519-25-2 | C19H26O8 382.405 g/mol |  |
| Unlike many other mycotoxins, trichothecenes do not require metabolic activation to exert their biological activity, instead directly reacting with cellular components...more Number of Targets: 2 |
| T3D2648 | Neoverrucotoxin Not Available | Not Available 79669.850 g/mol |  |
| Neoverrucotoxin has hemolytic activities. (T170) Number of Targets: 0 |
| T3D0136 | Neptunium-237 13994-20-2 | Np 237.048 g/mol |  |
| The ionizing radiation produced by neptunium causes cellular damage that includes DNA breakage, accurate or inaccurate repair, apoptosis, gene mutations, chromosomal c...more Number of Targets: 1 |
| T3D4929 | Nerolidol 7212-44-4 | C15H26O 222.366 g/mol |  |
| Not Available Number of Targets: 2 |
| T3D4168 | Niacinamide 98-92-0 | C6H6N2O 122.125 g/mol |  |
| Uremic toxins such as nicotinamide are actively transported into the kidneys via organic ion transporters (especially OAT3). Increased levels of uremic toxins can stim...more Number of Targets: 10 |
| T3D0053 | Nickel 7440-02-0 | Ni 58.692 g/mol |  |
| Nickel is known to substitute for other essential elements in certain enzmes, such as calcineurin. It is genotoxic, and some nickel compounds have been shown to promot...more Number of Targets: 73 |
| T3D0684 | Nickel acetate 373-02-4 | C4H14NiO8 248.843 g/mol |  |
| Nickel is known to substitute for other essential elements in certain enzmes, such as calcineurin. It is genotoxic, and some nickel compounds have been shown to promot...more Number of Targets: 68 |
| T3D1414 | Nickel aluminide 12003-78-0 | AlNi 85.675 g/mol |  |
| Nickel is known to substitute for other essential elements in certain enzmes, such as calcineurin. It is genotoxic, and some nickel compounds have been shown to promot...more Number of Targets: 71 |
| T3D0685 | Nickel ammonium sulfate hexahydrate 15699-18-0 | H8N2NiO8S2 286.896 g/mol |  |
| Nickel is known to substitute for other essential elements in certain enzmes, such as calcineurin. It is genotoxic, and some nickel compounds have been shown to promot...more Number of Targets: 68 |
| T3D1409 | Nickel arsenate 13477-70-8 | AsH3NiO4 200.636 g/mol |  |
| Nickel is known to substitute for other essential elements in certain enzmes, such as calcineurin. It is genotoxic, and some nickel compounds have been shown to promot...more Number of Targets: 112 |
| T3D1416 | Nickel bis(dibutyldithiocarbamate) 13927-77-0 | C18H36N2NiS4 467.445 g/mol |  |
| Nickel is known to substitute for other essential elements in certain enzmes, such as calcineurin. It is genotoxic, and some nickel compounds have been shown to promot...more Number of Targets: 68 |
| T3D0691 | Nickel bromide 13462-88-9 | Br2Ni 218.501 g/mol |  |
| Nickel is known to substitute for other essential elements in certain enzmes, such as calcineurin. It is genotoxic, and some nickel compounds have been shown to promot...more Number of Targets: 74 |